Quick and Spontaneous Transformation between [3Fe-4S] and [4Fe-4S] Iron-Sulfur Clusters in the tRNA-Thiolation Enzyme TtuA; 2023年01月 発表情報; International Jouranl of Molecular Science, in press 著者; Masato Ishizaka, Mihghao Chen, Shun Narai, Yoshikazu Tanaka, Toyoyuki Ose, Masaki Horitani*, and Min Yao*
Intermolecular Electron Transfer from Biopterin to FeII-O2 Complex in Nitric Oxide Synthases Occurs at very Different Rates Between Bacterial and Mammalian Enzymes: Direct Observation of a Catalytically Active Intermediate; 2023年01月 発表情報; Journal of Inorganic Biochemistry, 238, 112035 著者; Kazuo Kobayashi*, Yuko Tsutsui Ito, Yuri Kasu, Masaki Horitani, and Takahiro Kozawa
Trapping of Mono-Nitrosyl Non-Heme Intermediate of Nitric Oxide Reductase by Cryo-photolysis of Caged Nitric Oxide; 2023年00月 発表情報; Journal Physical Chemistry B, in press 著者; Hanae Takeda, Kanji Shimba, Masaki Horitani, Tetsunari Kimura, Takashi Nomura, Minoru Kubo, Yoshitsugu Shiro*, and Takehiko Tosha*
Heme Protein Identified from Scaly-Foot Gastropod can Synthesize Pyrite (FeS2) Nanoparticles; 2023年00月 発表情報; Acta Biomaterialia, in press 著者; Tatsuya Yamashita, Hiroki Matsuda, Kyohei Koizumi, Logu Thirumalaisamy, Myeongok Kim, Lumi Negishi, Hitoshi Kurumizaka, Yoriko Tominaga, Yoshihiro Takagi, Ken Takai, Taiga Okumura, Hidekazu Katayama, Masaki Horitani, Nazmul Ahsan, Yoshitaka Okada, Koji Nagata, Yohey Suzuki, Michio Suzuki*
The molecular mechanism of phytosphingosine binding to FFAR4/GPR120 differs from that of other fatty acids; 2021年11月 発表情報; FEBS open bio, 11, 11, 3081-3089 著者; Tomotaka Nagasawa, Masaki Horitani, Shin-ichi Kawaguchi, Shigeki Higashiyama, Yoichiro Hama, Susumu Mitsutake*
Biochemical Properties of CumA Multicopper Oxidase from Plant Pathogen, Pseudomonas syringae; 2021年07月 発表情報; Bioscience, Biotechnology, and Biochemistry, 85, 9, 1995-2002 著者; Konoan Ishida, Yuya Tsukamoto, Masaki Horitani*, Tomohisa Ogawa, and Yoshikazu Tanaka*
Timing of NO Binding and Protonation in the Catalytic Reaction of Bacterial Nitric Oxide Reductase as Established by Time-Resolved Spectroscopy; 2020年07月 発表情報; Bulletin of the Chemical Society of Japan, 93, 7, 825-833 著者; Hanae Takeda, Tetsunari Kimura, Takashi Nomura, Masaki Horitani, Azusa Yokota, Akiko Matsubayashi, Shoko Ishii, Yoshitsugu Shiro, Minoru Kubo*, Takehiko Tosha*
The [4Fe-4S] Cluster of Sulfurtransferase TtuA Desulfurizes TtuB during tRNA Modification in Thermus Thermophilus; 2020年04月 発表情報; Communications Biology, 3, 168, 1-9 著者; Minghao Chen, Masato Ishizaka, Shun Narai, Masaki Horitani, Naoki Shigi, Min Yao*, and Yoshikazu Tanaka*
X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy Reveal Active Site Rearrangement of Cold-Adapted Inorganic Pyrophosphatase; 2020年03月 発表情報; Scientific Reports, 10, 4368 著者; Masaki Horitani*, Kazuki Kusubayashi, Kyoka Oshima, Akane Yato, Hiroshi Sugimoto, and Keiichi Watanabe
An Ancient Type of MnmA Protein is an Iron-Sulfur Cluster-Dependent Sulfurtransferase for tRNA Anticodons; 2019年12月 発表情報; RNA, 25, 240-250 著者; Naoki Shigi*, Masaki Horitani, Kenjyo Miyauchi, Tsutomu Suzuki, and Misao Kuroki
Monovalent Cation Activation of the Radical SAM Enzyme Pyruvate Formate-Lyase Activating Enzyme; 2017年08月 発表情報; Journal of the American Chemical Society, 139, 34, 11803-11813 著者; Krista A. Shisler, Rachel U. Hutcheson, Masaki Horitani, Kaitlin S. Duschene, Adam V. Crain, Amanda S. Byer, Eric M. Shepard, Ashley Rasmussen, Jian Yang, William E. Broderick, Jessica L. Vey, Catherine L. Drennan, Brian M. Hoffman, and Joan B. Broderick
ENDOR Characterization of an Iron-Alkene Complex Provides Insight into a Corresponding Organometallic Intermediate of Nitrogenase; 2017年06月 発表情報; Chemical Science, 8, 5941-5948 著者; Masaki Horitani, Katarzyna Grubel, Sean F. McWilliams, Bryan D. Stubbert, Brandon Q. Mercado, Ying Yu, Prabhuodeyara M. Gurubasavaraj, Nicholas S. Lees, Patrick L. Holland, and Brian M. Hoffman
Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis; 2017年04月 発表情報; Journal of the American Chemical Society, 139, 16, 5680-5683 著者; Dong, Min; Horitani, Masaki; Dzikovski, Boris; Freed, Jack H.; Ealick, Steven E.; Hoffman, Brian M.; Lin, Hening
13C ENDOR spectroscopy of lipoxygenase-substrate complexes reveals the structural basis for C-H activation by tunneling; 2017年02月 発表情報; Journal of the American Chemical Society, 139, 5, 1984-1997 著者; Horitani, Masaki; Offenbacher, Adam R.; Marcus Carr, Cody A.; Yu, Tao; Hoeke, Veronika; Cutsail, George E.; Cutsail, George E.; Hammes-Schiffer, Sharon; Klinman, Judith P.; Klinman, Judith P.; Hoffman, Brian M.
Negative cooperativity in the nitrogenase Fe protein electron delivery cycle; 2016年10月 発表情報; Proceedings of the National Academy of Sciences of the United States of America, 113, 40, E5783-E5791 著者; Danyal, Karamatullah; Shaw, Sudipta; Page, Taylor R.; Duval, Simon; Horitani, Masaki; Marts, Amy R.; Lukoyanov, Dmitriy; Dean, Dennis R.; Raugei, Simone; Hoffman, Brian M.; Seefeldt, Lance C.; Antony, Edwin
Organometallic Complex Formed by an Unconventional Radical S-Adenosylmethionine Enzyme; 2016年08月 発表情報; Journal of the American Chemical Society, 138, 31, 9755-9758 著者; Dong, Min; Horitani, Masaki; Dzikovski, Boris; Pandelia, Maria Eirini; Krebs, Carsten; Freed, Jack H.; Hoffman, Brian M.; Lin, Hening;
Metalloproteins: Radical SAM catalysis via an organometallic intermediate with an Fe-[5′-C]-deoxyadenosyl bond; 2016年05月 発表情報; Science, 352, 6287, 822-825 著者; Horitani, Masaki; Shisler, Krista; Broderick, William E.; Hutcheson, Rachel U.; Duschene, Kaitlin S.; Marts, Amy R.; Hoffman, Brian M.; Broderick, Joan B.
Investigating the position of the hairpin loop in New Delhi metallo-β-lactamase, NDM-1, during catalysis and inhibitor binding; 2016年03月 発表情報; Journal of Inorganic Biochemistry, 156, 35-39 著者; Aitha, Mahesh; Moller, Abraham J.; Sahu, Indra D.; Horitani, Masaki; Tierney, David L.; Crowder, Michael W.
Why Nature Uses Radical SAM Enzymes so Widely: Electron Nuclear Double Resonance Studies of Lysine 2,3-Aminomutase Show the 5′-dAdo• "free Radical" Is Never Free; 2015年06月 発表情報; Journal of the American Chemical Society, 137, 22, 7111-7121 著者; Horitani, Masaki; Byer, Amanda S.; Shisler, Krista A.; Chandra, Tilak; Broderick, Joan B.; Hoffman, Brian M.
Characterization of the Fe-H bond in a three-coordinate terminal hydride complex of iron(I); 2012年04月 発表情報; Angewandte Chemie - International Edition, 51, 15, 3658-3662 著者; Chiang, Karen P.; Scarborough, Christopher C.; Horitani, Masaki; Lees, Nicholas S.; Ding, Keying; Dugan, Thomas R.; Brennessel, William W.; Bill, Eckhard; Hoffman, Brian M.; Holland, Patrick L.
Low-lying electronic states of the ferrous high-spin (S = 2) heme in deoxy-Mb and deoxy-Hb studied by highly-sensitive multi-frequency EPR; 2011年12月 発表情報; Journal of Inorganic Biochemistry, 105, 12, 1596-1602 著者; Hori, Hiroshi; Yashiro, Haruhiko; Ninomiya, Kenta; Horitani, Masaki; Kida, Takanori; Hagiwara, Masayuki
Resonance Raman study on the oxygenated and the ferryl-oxo species of indoleamine 2,3-dioxygenase during catalytic turnover; 2011年12月 発表情報; Faraday Discussions, 148, 239-247 著者; Yanagisawa, Sachiko; Horitani, Masaki; Sugimoto, Hiroshi; Shiro, Yoshitsugu; Okada, Norihiro; Ogura, Takashi
Resonance Raman identification of a FeIV=O type reaction intermediate during indoleamine 2, 3-dioxygenase reaction; 2010年12月 発表情報; AIP Conference Proceedings, 1267, 892-893 著者; Ogura, Takashi; Yanagisawa, Sachiko; Okada, Norihiro; Horitani, Masaki; Sugimoto, Hiroshi; Shiro, Yoshitsugu; Appelman, Evan H.
Identification of the Fe-O 2 and the Fe=O heme species for indoleamine 2,3-dioxygenase during catalytic turnover; 2010年02月 発表情報; Chemistry Letters, 39, 1, 36-37 著者; Yanagisawa, Sachiko; Yotsuya, Keiko; Hashiwaki, Yumi; Horitani, Masaki; Sugimoto, Hiroshi; Shiro, Yoshitsugu; Appelman, Evan H.; Ogura, Takashi
Multi-frequency and high-field EPR study of manganese(III) protoporphyrin IX reconstituted myoglobin with an S = 2 integer electron spin; 2008年04月 発表情報; Journal of Inorganic Biochemistry, 102, 4, 781-788 著者; Horitani, Masaki; Yashiro, Haruhiko; Hagiwara, Masayuki; Hori, Hiroshi
Development of a multi-frequency ESR system with high sensitivity; 2006年12月 発表情報; Journal of Physics: Conference Series, 51, 1, 576-579 著者; Yashiro, H.; Kashiwagi, T.; Horitani, M.; Hobo, F.; Hori, H.; Hagiwara, M.
EPR Spectroscopy Reveals the Differences of Active Site Structure for Di-Mn Enzymes from Mesophillic and Psychrophillic Bacteria; 2022年09月 発表情報; 第60回生物物理学会第60回年会 著者; Masaki Horitani
X-ray Crystallography and Spin-Labeling ESR Reveal Cold Adaptation and High Thermal Stability Mechanism of Cold-Adapted Glucokinase; 2022年09月 発表情報; 第60回生物物理学会第60回年会 著者; Akane Yato, Rio Asaka, Hiroshi Sugimoto, Keiichi Watanabe, Masaki Horitani
Crystal Structure of Soluble Family II Inorganic Pyrophosphatase Revealed the Mechanism of
Catalysis and Structure Dynamics; 2021年11月 発表情報; 第59回日本生物物理学会年会 著者; Kantaro Sakamoto, Hiroshi Sugimoto, Masaki Horitani
Analysis on Cold Adaptation Mechanism of Metalloenzyme by X-ray Crystallography and EPR Spectroscopy Combined with Rapid Freeze-Quench; 2021年08月 発表情報; 22nd International Society of Magnetic Resonance, 9th Asia-Pacific NMR Symposium (APNMR9), 60th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan (2021), 60th Annual Meeting of the Society of Electron Spin Science and Technology (SEST2021) 著者; Masaki Horitani, Yuri Kasu, Hiroshi Sugimoto, Keiichi Watanabe
X-ray Crystallography and Site-Directed Spin-Labeling ESR Reveal Cold Adaptation and High Thermal Stability Mechanisms of Cold-Adapted Glucokinase; 2021年08月 発表情報; 22nd International Society of Magnetic Resonance, 9th Asia-Pacific NMR Symposium (APNMR9), 60th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan (2021), 60th Annual Meeting of the Society of Electron Spin Science and Technology (SEST2021) 著者; Akane Yato, Rio Asaka, Hiroshi Sugimoto, Keiichi Watanabe, Masaki Horitani
Cold Adaptation and High Thermal Stability Mechanism of Glucokinase from psychrophillic bacteria are revealed by spin-labeling ESR; 2020年09月 発表情報; 第58回日本生物物理学会 著者; 矢垰 紅音, 堀谷 正樹
Substrate Positioning for H-Atom Abstraction in Soybean Lipoxygenase by ENDOR Crystallography; 2017年06月 発表情報; 第17回日本蛋白質科学会年会 著者; Masaki Horitani, Adam R. Offenbacher, Cody A. Marcus Carr, Tao Yu, Veronika Heke, George E. Cutsail III, Sharon Hammes-Schiffer, Judith P. Klinman, Brian M. Hoffman
ラジカルSAM酵素における有機金属反応中間体の観測; 2016年06月 発表情報; 第43回生体分子討論会 著者; 堀谷 正樹、Krista Shisler, William E. Broderick, Rachel U. Hatcheson, Kaitlin S. Duschene, Amy R. Marts, Brian M. Hoffman, Joan B. Broderick
New Approach to ENDOR Analysis for Manganese(II)-Substituted Soybean Lipoxygenase with A Non-Coordinated Substrate; 2014年11月 発表情報; Joint Conference of 9th Asia-Pacific EPR/ESR Society Symposium, 1st International EPR (ESR) Society Symposium, 53rd SEST Annual Meeting 著者; Masaki Horitani, George Cutsail III, Cody A. Marcus Carr, Adam R. Offenbacher, Judith P. Klinman, and Brian M. Hoffman
The Structural Analysis for Reaction Intermediate of Lysine 2,3-Aminomutase by ENDOR Spectroscopy; 2012年08月 発表情報; 神戸大学分子創成セミナー 著者; 堀谷 正樹
Elucidation of the tRNAsulfurationmechanism of TtuA involved inFe-S cluster; 2018年09月 発表情報; 第56回日本生物物理学会 著者; Masato Ishizaka, Minghao Chen, Syun Narai, Masaki Horitani, Seiko Oka, YoshikzauTanaka, and Min Yao
1P164 Analysis of Multi-Frequency and High-Field EPR Spectra for Powder and Single-Crystal of Mn(III)Mb with Integer Spin (S=2)(5. Heme protein,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006); 2006年10月 発表情報; 生物物理, 46, 2 著者; Horitani Masaki;Yashiro Haruhiko;Hagiwara Masayuki;Hori Hiroshi
1P515 Development of a High-Sensitivitive, Multi-Frequency EPR system as a New Tool for Research on Metalloproteins with Integer Electron Spin(25. New methods and tools (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006); 2006年10月 発表情報; 生物物理, 46, 2 著者; Yashiro Haruhiko;Kashiwagi Takanari;Horitani Masaki;Hori Hiroshi;Hagiwara Masayuki
EPR Spectroscopy and X-ray Crystallography Revealed Rearrangements of Di-Mn Active Site by Substrate Binding in Inorganic Pyrophosphatase; 2023年11月 発表情報; 10th Asian Biological Inorganic Chemistry Conference 著者; Masaki Horitani
EPR Spectroscopy Reveals Active Site Rearrangements of Di-Mn Center in Inorganic Pyrophosphatase; 2022年09月 発表情報; 錯体化学会第72回討論会 著者; Masaki Horitani
X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy Reveal Active Site Rearrangement of Cold Adaptation Enzyme; 2021年12月 発表情報; The Internatinal Chemical Congress of Pacific Basin Societies 2021 (Pacifichem 2021) 著者; Masaki Horitani, Hiroshi Sugimoto, Keiichi Watanabe
Advanced High Field and THz ESR Spectroscopic Studies on Heme Proteins with Integer Spin System; 2021年03月 発表情報; The 8th International Workshop on Far-Infrared Technologies 著者; Masaki Horitani, Haruna Ninomiya, Hideyuki Takahashi, Tsubasa Okamoto, Kana Nishikawa, Susumu Okubo, Eiichi Omichi, Hitoshi Ohta
X-ray Crystallography and EPR Spectroscopy Reveal Active Site Rearrangement of Cold-Adapted Inorganic Pyrophosphatase; 2020年09月 発表情報; 第58回日本生物物理学会年会 著者; Masaki Horitani, Hiroshi Sugimoto, Keiichi Watanabe
Cold Adaption Inorganic Pyrophosphatase from Shewanella sp. AS-11 was Investigated the Reaction Mechanism by X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy; 2019年08月 発表情報; International Congress on Pure & Applied Chemistry (ICPAC) Yangon 2019 著者; Masaki Horitani, Hiroshi Sugimoto, Keiichi Watanabe
EPR Spectroscopy Reveals the Active Site Rearrangement of Di-Mn2+ Center by Substrate Binding in Inorganic Pyrophosphatase from Shewanella sp. AS-11; 2019年06月 発表情報; Awaji Island Conference on Electron Spin Science & Technology 著者; Masaki Horitani, Hiroshi Sugimoto, Keiichi Watanabe
Electron Paramagnetic Resonance Spectroscopy Investigates Di-Manganese(II) Active Site of Inorganic Pyrophosphate from Shewanella sp. AS-11; 2018年10月 発表情報; 19th Malaysian International Chemistry Congress and International Congress on Pure & Applied Chemistry Langkawi 2018 著者; Masaki Horitani
EPR Studies Reveal Mn(II)-Mn(II) Distance in the Active Site of Inorganic Pyrophosphatase from Shewanella sp. AS-11; 2018年09月 発表情報; The Third Joint Conference of the Asia-Pacific EPR/ESR Society and The International EPR (ESR) Society 著者; Masaki Horitani
New ENDOR Analysis Reveals the Structural Basis for C-H Activation by Biological Tunneling in Soybean Lipoxygenase; 2017年06月 発表情報; The 5th Awaji International Workshop on Electron Spin Science & Technology: Biological and Materials Science Oriented Applications (AWEST) 著者; Masaki Horitani, Adam R. Offenbacher, Cody A. Marcus Carr, Tao Yu, Veronika Heke, George E. Cutsail III, Sharon Hammes-Schiffer, Judith P. Klinman, Brian M. Hoffman
ENDOR reveals how radical SAM enzymes tame highly reactive radical; 2016年11月 発表情報; Molecular Photoscience Research Center International Workshop “Novel Magnetic Resonance Techniques in Millimeter and Terahertz Waves and their Applications to Bioscience” (MR-THz2016) 著者; Masaki Horitani, Krista Shisler, William E. Broderick, Rachel U. Hatcheson, Kaitlin S. Duschene, Amy R. Marts, Brian M. Hoffman, Joan B. Broderick
Radical SAM Catalysis via an Organometallic Intermediate with an Fe-[5’C-Deoxyadenosyl] Bond; 2016年06月 発表情報; The 4th Awaji International Workshop on Electron Spin Science & Technology: Biological and Materials Science Oriented Applications (AWEST) 著者; Masaki Horitani, Krista Shisler, William E. Broderick, Rachel U. Hatcheson, Kaitlin S. Duschene, Amy R. Marts, Brian M. Hoffman, Joan B. Broderick
なぜラジカルSAM酵素は生物界に幅広く受け入れられてきたか
~ラジカルSAM酵素の持つラジカル反応機構の解明~; 2015年12月 発表情報; BMB2015 著者; Masaki Horitani, Amanda S. Byer, Krista A. Shisler, Tilak Chandra, Joan B. Broderick, and Brian M. Hoffman
Why Nature Uses Radical SAM Enzymes so Widely ~ENDOR Studies on Lysine 2,3-Aminomutase Show the 5’-dAdo• ‘Free Radical’ is Never Free~; 2015年06月 発表情報; The 3rd Awaji International Workshop on Electron Spin Science & Technology: Biological and Materials Science Oriented Applications (AWEST) 著者; Masaki Horitani, Amanda S. Byer, Krista A. Shisler, Tilak Chandra, Joan B. Broderick, and Brian M. Hoffman