日本語フィールド
著者：Yanagisawa, Sachiko; Yotsuya, Keiko; Hashiwaki, Yumi; Horitani, Masaki; Sugimoto, Hiroshi; Shiro, Yoshitsugu; Appelman, Evan H.; Ogura, Takashi題名：Identification of the Fe-O 2 and the Fe=O heme species for indoleamine 2,3-dioxygenase during catalytic turnover発表情報：Chemistry Letters 巻: 39 号: 1 ページ: 36-37キーワード：概要：Resonance Raman spectroscopy has been applied to two distinct temporal species of indoleamine 2,3-dioxygenase during catalytic turnover. We have identified two oxygen-isotopesensitive Raman modes at 569 and 798 cm -1 for the two respective species. The 16O 18O analysis of the 798 cm -1 band indicates the existence of a ferryl-oxo heme, which is inconsistent with the previously proposed reaction mechanism. The present study thus provides a physical basis for the structures of the possible reaction intermediates. © 2010 The Chemical Society of Japan.抄録：英語フィールド
Author：Yanagisawa, Sachiko; Yotsuya, Keiko; Hashiwaki, Yumi; Horitani, Masaki; Sugimoto, Hiroshi; Shiro, Yoshitsugu; Appelman, Evan H.; Ogura, TakashiTitle：Identification of the Fe-O 2 and the Fe=O heme species for indoleamine 2,3-dioxygenase during catalytic turnoverAnnouncement information:Chemistry Letters Vol: 39 Issue: 1 Page: 36-37An abstract：Resonance Raman spectroscopy has been applied to two distinct temporal species of indoleamine 2,3-dioxygenase during catalytic turnover. We have identified two oxygen-isotopesensitive Raman modes at 569 and 798 cm -1 for the two respective species. The 16O 18O analysis of the 798 cm -1 band indicates the existence of a ferryl-oxo heme, which is inconsistent with the previously proposed reaction mechanism. The present study thus provides a physical basis for the structures of the possible reaction intermediates. © 2010 The Chemical Society of Japan.