Detailed Information

Research Field/Keywords for Research Field

• Hygiene, Public Health, Toxicology

Education

• 1999/03, Graduated

Employment Experience

• 1999/06 - 2000/05
• 2000/06 - 2002/11 Research Associate
• 2002/04 - 2007/03 Research Associate, Medicine, Faculty of Medicine, Saga University
• 2002/12 - 2003/09 Research Associate
• 2007/04 - 2009/12 Assistant Professor, Medicine, Faculty of Medicine, Saga University
• 2009/11 - 2010/11 Visiting research associate Molecular Toxicology Department of Pharmaceutical Science University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences
• 2011/12 -  *  Lecturer, Medicine, Faculty of Medicine, Saga University

Field of Specialization

• Hygiene and public health, Epidemiology and preventive medicine, Gastroenterology, Psychiatric science, Environmental and hygienic pharmacy

Themes for Ongoing Research

• Study on ALDH superfamily

Research Topics and Results

• Ethanol Metabolism and Melanoma  2023/02
• ALDH2 rs671 variant allele is associated with higher energy intake in middle-aged and elderly Japanese who routinely consume alcohol  2023
• Metabolic changes with ethanol and ALDH2 inhibition in human melanocytes 2022/12
• Acceptance of Booster COVID-19 Vaccine and Its Association with Components of Vaccination Readiness in the General Population: A Cross-Sectional Survey for Starting Booster Dose in Japan 2022/07
• Variant Allele of ALDH2, rs671, Associates with Attenuated Post-Vaccination Response in Anti-SARS-CoV-2 Spike Protein IgG: A Prospective Study in the Japanese General Population  2022/06
• 5G millimeter-wave exposure of rat dorsal skin regulates body temperature and distal blood flow 2022/06
• Effects of wide area exposure to 28 GHz-plane waves on back skin in human volunteer 2022/06
• Association of Vaccine Confidence and Hesitancy in Three Phases of COVID-19 Vaccine Approval and Introduction in Japan  2022/03
• Comparison of CLEIA and ELISA for SARS-CoV-2 Virus Antibodies after First and Second Dose Vaccinations with the BNT162b2 mRNA Vaccine  2022/03
• EL2-01.Importance of ALDH2 polymorphism rs671 in public health and medicine 2022
• [1P-763]Aldehyde dehydrogenase 2 deficiency affects epithelial barrier and airway hyper responsiveness in allergic asthma model mouse 2022
• Effects of high intensity local exposure to 26.5 GHz-millimeter-waves on neuronal cells in rat brain 2021/09
• Ethanol induces melanocyte proliferation, melanin pigmentation, and DNA damage in Aldh2 KO mice 2021/09
• ALDH2 polymorphism rs671 is a predictor of PD-1/PD-L1 inhibitor efficacy against thoracic malignancies  2021/05
• Perceived stress, depressive symptoms, and cortisol-to-cortisone ratio in spot urine in 6878 older adults 2021/03
• Whole-body insulin resistance and energy expenditure indices, serum lipids, and skeletal muscle metabolome in a state of lipoprotein lipase overexpression  2021/02
• Occupational exposure limits for acetaldehyde, 2-bromopropane, glyphosate, manganese and inorganic manganese compounds, and zinc oxide nanoparticle, and the biological exposure indices for cadmium and cadmium compounds and ethylbenzene, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications  2021/01
• Ethanol induces melanin pigmentation and cyclobutene pyrimidine dimers (CPD) in ALDH2 KO mice 2020/06
• The Bidirectional Effect of Defective ALDH2 Polymorphism and Disease Prevention. 2019/07
• Occupational exposure limits for cumene, 2,4-dichlorophenoxy acetic acid, silicon carbide whisker, benzyl alcohol, and methylamine, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications. 2019/07
• Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency. 2019/04
• The role of ethanol and ALDH2 in activating melanocytes. 2019
• Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency. 2019
• The role of ethanol and ALDH2 in activating melanocytes. 2019
• Acetaldehyde administration induces salsolinol formation in vivo in the dorsal striatum of Aldh2-knockout and C57BL/6N mice. 2018/10
• Occupational Exposure Limits for ethylidene norbornene, ethyleneimine, benomyl, and 2,3-epoxypropyl methacrylate, and classifications on carcinogenicity 2018/07
• Variability and reliability of POPs concentrations in multiple breast milk samples collected from the same mothers 2018/06
• Concentration determination of urinary metabolites of N,N-dimethylacetamide by high-performance liquid chromatography-tandem mass spectrometry 2018/03
• Award Article Importance of an Aldehyde Dehydrogenase 2 Polymorphism in Preventive Medicine 2018/01
• Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis. 2018
• A novel phenotype of ALDH2 polymorphism: alcohol-induced skin pigmentation 2018
• Alcohol-induced skin pigmentation: a novel phenotype of ALDH2 gene variant 2018
• Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant. 2017
• Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer. 2017
• Development of suitable method for large-scale urinary glucocorticoid analysis by liquid chromatography-mass spectrometry. 2017
• A novel phenotype of ALDH2 polymorphism: drinking-induced skin pigmentation 2017
• Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway. 2016
• Heme oxygenase 1 protects ethanol-administered liver tissue in Aldh2 knockout mice. 2016
• Roles of defective ALDH2 polymorphism on liver protection and cancer development. 2016
• Significance of defective polymorphism of aldehyde dehydrogenase 2 gene (ALDH2) in prenatal toxicology 2016
• ALDH1B1 links alcohol consumption and diabetes. 2015
• Ethanol reduces lifespan, body weight, and serum alanine aminotransferase level of aldehyde dehydrogenase 2 knockout mouse. 2014
• Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice. 2014
• Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity. 2014
• Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke‐induced DNA damage and cytotoxicity. 2013
• Simultaneous measurement of urinary total nicotine and cotinine as biomarkers of active and passive smoking among Japanese individuals. 2013
• Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress. 2013
• Increased formation of gastric N(2)-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanol. 2009/02
• Effects of 5-week ethanol feeding on the liver of aldehyde dehydrogenase 2 knockout mice. 2008/10
• Single-dose ethanol administration downregulates expression of cytochrome p450 2E1 mRNA in aldehyde dehydrogenase 2 knockout mice. 2008/10
• Single-dose ethanol administration downregulates expression of cytochrome p450 2E1 mRNA in aldehyde dehydrogenase 2 knockout mice. 2007
• Increased formation of hepatic N2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2-knockout mice treated with ethanol. 2007
• Analysis of urinary metabolites of polycyclic aromatic hydrocarbons in incineration workers. 2007
• Lack of aldehyde dehydrogenase ameliorates oxidative stress induced by single-dose ethanol administration in mouse liver. 2007
• ALDH2 transgenic knockout mice dislike alcohol drinking and receive more severe acetaldehyde toxicity. 2007
• Decreasing urinary PAH metabolites and 7-methylguanine after smoking cessation. 2006
• Hepatocyte necrosis is inhibited in ethanol administered transgenic mice lacking aldehyde dehydrogenase 2 activit 2006
• Urinary 8-hydoxydeoxyguanosine (8-OHdG) and plasma malondialdehyde (MDA) levels in Aldh2 knock-out mice under acetaldehyde exposure. 2005
• Identification of cytochrome P450 isoforms involved in 1-hydroxylation of pyrene. 2004

Books

• Bisphenol A;　2003
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  

Original Articles

• ALDH2 rs671 variant allele is associated with higher energy intake in middle-aged and elderly Japanese who routinely consume alcohol ;　2023
  ANNOUNCEMENT INFO.;　Environ Health Prev Med, 28, 29
  AUTHOR;　*Hayashida H, Matsumoto A, Nanri H, Nishida Y, Takagi Y, Hara M
  
• Acceptance of Booster COVID-19 Vaccine and Its Association with Components of Vaccination Readiness in the General Population: A Cross-Sectional Survey for Starting Booster Dose in Japan;　2022/07
  ANNOUNCEMENT INFO.;　Vaccines (Basel), 10, 7, 1102
  AUTHOR;　Mikiko Tokiya, Megumi Hara, Akiko Matsumoto, Mohammad Said Ashenagar, Takashi Nakano, Yoshio Hirota
  
• Variant Allele of ALDH2, rs671, Associates with Attenuated Post-Vaccination Response in Anti-SARS-CoV-2 Spike Protein IgG: A Prospective Study in the Japanese General Population ;　2022/06
  ANNOUNCEMENT INFO.;　Vaccines (Basel), 10, 7, 1035
  AUTHOR;　Akiko Matsumoto, Megumi Hara, Mohammad Said Ashenagar, Mikiko Tokiya, Takeshi Sawada, Chiharu Iwasaka, Takuma Furukawa, Kyoko Kitagawa, Yasunobu Miyake, Yoshio Hirota
  
• Association of Vaccine Confidence and Hesitancy in Three Phases of COVID-19 Vaccine Approval and Introduction in Japan ;　2022/03
  ANNOUNCEMENT INFO.;　Vaccines (Basel), 10, 3, 423
  AUTHOR;　*Mikiko Tokiya, Megumi Hara, Akiko Matsumoto, Mohammad Said Ashenagar, Takashi Nakano, Yoshio Hirota
  
• Comparison of CLEIA and ELISA for SARS-CoV-2 Virus Antibodies after First and Second Dose Vaccinations with the BNT162b2 mRNA Vaccine ;　2022/03
  ANNOUNCEMENT INFO.;　Vaccines (Basel), 10, 4, 487
  AUTHOR;　Mohammad Said Ashenagar, Akiko Matsumoto, Hironori Sakai, Mikiko Tokiya, Megumi Hara, Yoshio Hirota
  
• ALDH2 polymorphism rs671 is a predictor of PD-1/PD-L1 inhibitor efficacy against thoracic malignancies ;　2021/05
  ANNOUNCEMENT INFO.;　BMC Cancer, 21, 1, 584
  AUTHOR;　Akiko Matsumoto, Chiho Nakashima, Shinya Kimura, Eizaburo Sueoka, Naoko Aragane
  
• Perceived stress, depressive symptoms, and cortisol-to-cortisone ratio in spot urine in 6878 older adults;　2021/03
  ANNOUNCEMENT INFO.;　Psychoneuroendocrinology, 125, 105125
  AUTHOR;　○Shimanoe C, Matsumoto A, Hara M, Akao C, Nishida Y, Horita M, Nanri H, Higaki Y, Tanaka K
  
• Whole-body insulin resistance and energy expenditure indices, serum lipids, and skeletal muscle metabolome in a state of lipoprotein lipase overexpression ;　2021/02
  ANNOUNCEMENT INFO.;　Metabolomics, 17, 3, 26
  AUTHOR;　○Yuichiro Nishida, Kazutoshi Nishijima, Yosuke Yamada, Hiroaki Tanaka, Akiko Matsumoto, Jianglin Fan, Yoichi Uda, Hajime Tomatsu, Hiroyuki Yamamoto, Kenjiro Kami, Shuji Kitajima, Keitaro Tanaka
  
• Occupational exposure limits for acetaldehyde, 2-bromopropane, glyphosate, manganese and inorganic manganese compounds, and zinc oxide nanoparticle, and the biological exposure indices for cadmium and cadmium compounds and ethylbenzene, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications ;　2021/01
  ANNOUNCEMENT INFO.;　J Occup Health, 63, 1, e12294
  AUTHOR;　Committee for Recommendation of Occupational Exposure Limits, Japan Society for Occupational Health(Masayoshi Ichiba and Akiko Matsumoto et al)
  
• Occupational exposure limits for cumene, 2,4-dichlorophenoxy acetic acid, silicon carbide whisker, benzyl alcohol, and methylamine, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications.;　2019/07
  ANNOUNCEMENT INFO.;　J Occup Health. , 61, 4, 328-330
  AUTHOR;　＊Araki A, Azuma K, Endo G, Endo Y, Fukushima T, Hara K, Harada K, Hori H, Horie S, Ichiba M, Ichihara G, Ikeda M, Ito A, Ito Y, Iwasawa S, Kakumu T, Kamijima M, Karita K, Katoh T, Kawai T, Kawamoto T, Kumagai S, Kusaka Y, Matsumoto A, et al.
  
• Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency.;　2019/04
  ANNOUNCEMENT INFO.;　Chem Biol Interact. , 302, 61-66
  AUTHOR;　Matsumoto A, Ito S, Wakamatsu K, Ichiba M, Vasiliou V, Akao C, Song BJ, Fujita M.
  
• Acetaldehyde administration induces salsolinol formation in vivo in the dorsal striatum of Aldh2-knockout and C57BL/6N mice.;　2018/10
  ANNOUNCEMENT INFO.;　Neurosci Lett. , 685, 50-54
  AUTHOR;　＊Ito A, Jamal M, Ameno K, Tanaka N, Takakura A, Kawamoto T, Kitagawa K, Nakayama K, Matsumoto A, Miki T, Kinoshita H.
  
• Occupational Exposure Limits for ethylidene norbornene, ethyleneimine, benomyl, and 2,3-epoxypropyl methacrylate, and classifications on carcinogenicity;　2018/07
  ANNOUNCEMENT INFO.;　J Occup Health. , 60, 4, 333-335
  AUTHOR;　Committee for Recommendation of Occupational Exposure Limits, Japan Society for Occupational Health, Araki A, Azuma K, Endo G, Endo Y, Fukushima T, Hara K, Hori H, Horie S, Horiguchi H, Ichiba M, Ichihara G, Ikeda M, Ishitake T, Ito A, Ito Y, Iwasawa S, Kakumu T, Kamijima M, Karita K, Katoh T, Kawai T, Kawamoto T, Kumagai S, Kusaka Y, Matsumoto A, et al
  
• Variability and reliability of POPs concentrations in multiple breast milk samples collected from the same mothers;　2018/06
  ANNOUNCEMENT INFO.;　Environ Sci Pollut Res Int. , 25, 17, 16309-16315
  AUTHOR;　〇Kakimoto R, Ichiba M, Matsumoto A, Nakai K, Tatsuta N, Iwai-Shimada M, Ishiyama M, Ryuda N, Someya T, Tokumoto I, Ueno D
  
• Concentration determination of urinary metabolites of N,N-dimethylacetamide by high-performance liquid chromatography-tandem mass spectrometry;　2018/03
  ANNOUNCEMENT INFO.;　J Occup Health. , 60, 2, 140-147
  AUTHOR;　Yamamoto S, Matsumoto A, Yui Y, Miyazaki S, Kumagai S, Hori H, Ichiba M
  
• Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant.;　2017
  ANNOUNCEMENT INFO.;　J Occup Health. , 59, 4, 364-366
  AUTHOR;　*Azuma K, Endo G, Endo Y, Fukushima T, Hara K, Hori H, Horie S, Horiguchi H, Ichiba M, Ichihara G, Ikeda M, Ishitake T, Ito A, Ito Y, Iwasawa S, Kamijima M, Karita K, Katoh T, Kawai T, Kawamoto T, Kishi R, Kumagai S, Kusaka Y, Matsumoto A, Miyagawa M, Miyauchi H, Morimoto Y, Nagano K, Naito H, Nakajima T, Nomiyama T, Okuda H, Omae K, Sakurai H, Sato K, Sobue T, Suwazono Y, Takebayashi T, Takeshita T, Takeuchi A, Takeuchi A, Tanaka M, Tanaka S, Tsukahara T, Tsunoda M, Ueno S, Ueyama J, Umeda Y, Yamano Y, Yamauchi T, Yano E.
  
• Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer.;　2017
  ANNOUNCEMENT INFO.;　Br J Cancer. , 117, 10, 1537-1543
  AUTHOR;　Matsumoto A, Arcaroli J, Chen Y, Gasparetto M, Neumeister V, Thompson DC, Singh S, Smith C, Messersmith W, Vasiliou V.
  
• Development of suitable method for large-scale urinary glucocorticoid analysis by liquid chromatography-mass spectrometry.;　2017
  ANNOUNCEMENT INFO.;　J Chromatogr B Analyt Technol Biomed Life Sci. , 1057, 62-69
  AUTHOR;　Matsumoto A, Shimanoe C, Tanaka K, Ichiba M, Hara M.
  
• Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway.;　2016
  ANNOUNCEMENT INFO.;　Sci Rep., 6, 29743
  AUTHOR;　* Chen Y, Singh S, Matsumoto A, Manna SK, Abdelmegeed MA, Golla S, Murphy RC, Dong H, Song BJ, Gonzalez FJ, Thompson DC, Vasiliou V.
  
• Heme oxygenase 1 protects ethanol-administered liver tissue in Aldh2 knockout mice.;　2016
  ANNOUNCEMENT INFO.;　Alcohol, 52, 49-54
  AUTHOR;　Matsumoto A, Thompson DC, Chen Y, Vasiliou V, Kawamoto T, Ichiba M
  
• ALDH1B1 links alcohol consumption and diabetes.;　2015
  ANNOUNCEMENT INFO.;　Biochem Biophys Res Commun., 463, 4, 768-73
  AUTHOR;　*Singh S, Chen Y, Matsumoto A, Orlicky DJ, Dong H, Thompson DC, Vasiliou V.
  
• Ethanol reduces lifespan, body weight, and serum alanine aminotransferase level of aldehyde dehydrogenase 2 knockout mouse.;　2014
  ANNOUNCEMENT INFO.;　Alcohol Clin Exp Res. , 38, 7, 1883-93
  AUTHOR;　Matsumoto A, Vasiliou V, Kawamoto T, Tanaka K, Ichiba M.
  
• Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.;　2014
  ANNOUNCEMENT INFO.;　Hepatology. , 60, 1, 146-57
  AUTHOR;　*Kwon HJ, Won YS, Park O, Chang B, Duryee MJ, Thiele GE, Matsumoto A, Singh S, Abdelmegeed MA, Song BJ, Kawamoto T, Vasiliou V, Thiele GM, Gao B.
  
• Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.;　2014
  ANNOUNCEMENT INFO.;　Free Radic Biol Med. , 68, 80-6
  AUTHOR;　*Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T.
  
• Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke‐induced DNA damage and cytotoxicity.;　2013
  ANNOUNCEMENT INFO.;　Free Radic Biol Med. Epub ahead of print
  AUTHOR;　*Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T.
  
• Simultaneous measurement of urinary total nicotine and cotinine as biomarkers of active and passive smoking among Japanese individuals.;　2013
  ANNOUNCEMENT INFO.;　Environ Health Prev Med., 18, 3, 244-250
  AUTHOR;　Matsumoto A, Matsumoto A, Ichiba M, Payton NM, Oishi H, Hara M.
  
• Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress.;　2013
  ANNOUNCEMENT INFO.;　Free Radic Biol Med., 56, 89-101
  AUTHOR;　*Singh S, Brocker C, Koppaka V, Chen Y, Jackson BC, Matsumoto A, Thompson DC, Vasiliou V.
  
• Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer.;　2011
  ANNOUNCEMENT INFO.;　, 405, 2, 173-9
  AUTHOR;　Chen Y, Orlicky DJ, Matsumoto A, Singh S, Thompson DC, Vasiliou V.
  
• Increased formation of gastric N(2)-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanol.;　2009/02
  ANNOUNCEMENT INFO.;　Mutat Res., 673, 1, 74-77
  AUTHOR;　Nagayoshi H, Matsumoto A, Nishi R, Kawamoto T, Ichiba M, Matsuda T.
  
• Effects of 5-week ethanol feeding on the liver of aldehyde dehydrogenase 2 knockout mice.;　2008/10
  ANNOUNCEMENT INFO.;　Pharmacogenet Genomics., 18, 10, 847-852
  AUTHOR;　Matsumoto A, Kawamoto T, Mutoh F, Isse T, Oyama T, Kitagawa K, Nakayama KI, Ichiba M.
  
• Single-dose ethanol administration downregulates expression of cytochrome p450 2E1 mRNA in aldehyde dehydrogenase 2 knockout mice.;　2007
  ANNOUNCEMENT INFO.;　Alcohol, 41, 8, 587-589
  AUTHOR;　Matsumoto A, Kawamoto T, Horita M, Takahashi T, Isse T, Oyama T, Ichiba M.
  
• Increased formation of hepatic N2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2-knockout mice treated with ethanol.;　2007
  ANNOUNCEMENT INFO.;　Carcinogenesis, 28, 11, 2363-2366
  AUTHOR;　Matsuda T, Matsumoto A, Uchida M, Kanaly RA, Misaki K, Shibutani S, Kawamoto T, Kitagawa K, Nakayama KI, Tomokuni K, Ichiba M.
  
• Analysis of urinary metabolites of polycyclic aromatic hydrocarbons in incineration workers.;　2007
  ANNOUNCEMENT INFO.;　J Occup Health, 49, 2, 159-164
  AUTHOR;　Ichiba M, Ogawa Y, Mohri I, Kondoh T, Horita M, Matsumoto A, Yoshida R, Matsumoto Y, Saito H, Ohba K, Yamashita Z, Tomokuni K.
  
• Lack of aldehyde dehydrogenase ameliorates oxidative stress induced by single-dose ethanol administration in mouse liver.;　2007
  ANNOUNCEMENT INFO.;　Alcohol, 41, 1, 57-59
  AUTHOR;　Matsumoto A, Ichiba M, Horita M, Yamashita Z, Takahashi T, Isse T, Oyama T, Kawamoto T, Tomokuni K.
  
• Decreasing urinary PAH metabolites and 7-methylguanine after smoking cessation.;　2006
  ANNOUNCEMENT INFO.;　Int Arch Occup Environ Health., 79, 7, 545-549
  AUTHOR;　Ichiba M, Matsumoto A, Kondoh T, Horita M, Tomokuni K.
  
• Urinary 8-hydoxydeoxyguanosine (8-OHdG) and plasma malondialdehyde (MDA) levels in Aldh2 knock-out mice under acetaldehyde exposure.;　2005
  ANNOUNCEMENT INFO.;　Ind Health, 44, 1, 179-183
  AUTHOR;　Ogawa M, Isse T, Oyama T, Kunugita N, Yamaguchi T, Kinaga T, Narai R, Matsumoto A, Kim YD, Kim H, Uchiyama I, Kawamoto T.
  
• Identification of cytochrome P450 isoforms involved in 1-hydroxylation of pyrene.;　2004
  ANNOUNCEMENT INFO.;　Environ Res., 94, 3, 262-266
  AUTHOR;　Kim YD,Todoroki H,Oyama T,Isse T,Matsumoto A,Yamaguchi T,Kim H,Uchiyama I,Kawamoto T
  
• Identification of cytochrome P450 isoforms involved in 1-hydroxylation of pyrene.;　2004
  ANNOUNCEMENT INFO.;　Environ Res., 94, 3, 262-266
  AUTHOR;　Kim YD,Todoroki H,Oyama T,Isse T,Matsumoto A,Yamaguchi T,Kim H,Uchiyama I,Kawamoto T
  
• Effects of Genetic Polymorphism of Drug Metabolizing Enzymes on Smoking and Drinking.;　2003
  ANNOUNCEMENT INFO.;　J. UOEH., 25, Suppl, 97-106
  AUTHOR;　Kawamoto T, Isse T, Kunugita N, Yang M, Kitagawa K, Suenaga R, Matsumoto A, Oyama T
  
• Bisphenol A levels in human urine.;　2003
  ANNOUNCEMENT INFO.;　Environ. Health Perspect., 111, 1, 101-104
  AUTHOR;　Matsumoto A, Kunugita N, Kitagawa K, Isse T, Oyama T, Foureman GL, Morita M, Kawamoto T
  
• Lung Cancer and CYP1A1 or GSTM1 Polymorphisms.;　2003
  ANNOUNCEMENT INFO.;　Environmental Health and Preventive Medidne., 7, 6, 230-234
  AUTHOR;　Oyama T, Kagawa N, Kim YD, Matsumoto A, Isse T, Kawamoto T
  
• A case-case study comparing the usefulness of serum trace elements (Cu,Zn and Se)and tumor markers (CEA,SCC and SLX) in non-small cell lung cancer patients.;　2003
  ANNOUNCEMENT INFO.;　Anticancer Res., 23, 1B, 605-612
  AUTHOR;　Oyama T, Kawamoto T, Matsuno K, Osaki T, Matsumoto A, Isse T, Nakata S, Ozaki S, Sugaya M, Yasuda M, Yamashita T, Takenoyama M, Sugio K, Yasumoto K
  
• Evidence based prevention (EBP):evidence-based approach to prevention of lung cancer by application of cytochrome 2E1 polymorphism.;　2003
  ANNOUNCEMENT INFO.;　Anticancer Res., 23, 1731-1738
  AUTHOR;　Oyama T, Matsumoto A, Isse T, Kim YD, Ozaki S, Ozaki T, Sugio K, Yasumoto K, Kawamoto T
  

Material, Commentary, Editorials, Research Report, A Comprehensive Journal Articles

• Evolutionary divergence and functions of the human interleukin (IL) gene family.;　2010
  ANNOUNCEMENT INFO.;　, 5, 1, 30-55
  AUTHOR;　
  
• Approach to sick building problem in schools: a workshop "saga forum on environment" project.;　2009/01
  ANNOUNCEMENT INFO.;　Nippon Eiseigaku Zasshi., 64, 1, 26-31
  AUTHOR;　Ichiba M, Takahashi T, Yamashita Z, Takaishi K, Nishimura K, Kamachi M, Kondoh T, Matsumoto A, Ueno D, Miyajima T.
  

General Lectures

• Metabolic changes with ethanol and ALDH2 inhibition in human melanocytes;　2022/12
  ANNOUNCEMENT INFO.;　Toxic Metabolites in the Biology of Ageing and Cancer (Hybrid event), 2022, 12, 4-7 (On-site+On-line)
  AUTHOR;　*Yamauchi T, Zhai Z, Nguyen K, Matsumoto A, Bergman B, D’Alessandro A, Fujita M
  
• 5G millimeter-wave exposure of rat dorsal skin regulates body temperature and distal blood flow;　2022/06
  ANNOUNCEMENT INFO.;　BioEM 2022(Hybrid event), 2022, 6,19-24(On-site+On-line)
  AUTHOR;　*Ijima E, Ishitake T, Hirata A, Kodera S, Matsumoto A, Hikage T, Masuda H
  
• Effects of wide area exposure to 28 GHz-plane waves on back skin in human volunteer;　2022/06
  ANNOUNCEMENT INFO.;　BioEM 2022(Hybrid event), 2022, 6,19-24(On-site+On-line)
  AUTHOR;　*Inoue M, Ijima E, Ishitake T, Matsumoto A, Hikage T, Hirata A, Kodera S, Masuda H
  
• [1P-763]Aldehyde dehydrogenase 2 deficiency affects epithelial barrier and airway hyper responsiveness in allergic asthma model mouse;　2022
  ANNOUNCEMENT INFO.;　MBSJ2022 Cooperated by the Biophysical Society of Japan(Hybrid event), 2022,11,30-12, 2(On-site+On-line)
  AUTHOR;　○Takeshi Sawada, Reiko U. Yoshimoto, Akiko Matsumoto, Masanori Makino, Weiqi Gao, Ailin Cao, Teppei Fukuyama, Ryunosuke Koga, Muzuho A. Kido
  
• Effects of high intensity local exposure to 26.5 GHz-millimeter-waves on neuronal cells in rat brain;　2021/09
  ANNOUNCEMENT INFO.;　BioEM2021(hybrid model), 2021, 9, 26-30
  AUTHOR;　*Ijima E, Ishitake T, Hirata A, Kodera S, Matsumoto A, Hikage T, Masuda H
  
• Ethanol induces melanocyte proliferation, melanin pigmentation, and DNA damage in Aldh2 KO mice;　2021/09
  ANNOUNCEMENT INFO.;　PASPCR 2021 Annual Meeting(hybrid event), 2021, 9, 22-25
  AUTHOR;　*Yamauchi T, Matsumoto A, Zhai Z, Gao B, Song BJ, Ito S, Wakamatsu K, Brash DE, Fujita M
  
• Ethanol induces melanin pigmentation and cyclobutene pyrimidine dimers (CPD) in ALDH2 KO mice;　2020/06
  ANNOUNCEMENT INFO.;　24th The International Pigment Cell Conference (IPCC2020) （On program booklet）, 2020, 6, 18-21
  AUTHOR;　*Yamauchi T, Matsumoto A, Ito S, Wakamatsu K, Suzuki T, Zhai Z, Fujita M
  
• The role of ethanol and ALDH2 in activating melanocytes.;　2019
  ANNOUNCEMENT INFO.;　4th Alcohol and Cancer Conference, 2019, 4, 14-18
  AUTHOR;　*Yamauchi T, Matsumoto A, Ito S, Wakamatsu K, Suzuki T, Zhai Z, Fujita M.
  
• Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency.;　2019
  ANNOUNCEMENT INFO.;　77th Annual SID Meeting, 2019, 5, 8-11
  AUTHOR;　*Yamauchi T, Matsumoto A, Ito S, Wakamatsu K, Suzuki T, Fujita M.
  
• The role of ethanol and ALDH2 in activating melanocytes.;　2019
  ANNOUNCEMENT INFO.;　PASPCR Annual Meeting 2019, 2019, 10, 2-4
  AUTHOR;　*Yamauchi T, Matsumoto A, Ito S, Wakamatsu K, Suzuki T, Zhai Z, Fujita M.
  
• A novel phenotype of ALDH2 polymorphism: alcohol-induced skin pigmentation;　2018
  ANNOUNCEMENT INFO.;　AIRIG2018 - 2018 Alcohol and Immunology Research Interest Group (AIRIG) meeting, 2018, 1, 26
  AUTHOR;　Matsumoto A, Hara T, Shimanoe C, Yuzuriha T, Yoshimori C, Muto T, Endo K, Hara M, Ichiba M, Konakahara T, Yajima I, Vasiliou V, Song BJ, Fujita M
  
• Alcohol-induced skin pigmentation: a novel phenotype of ALDH2 gene variant;　2018
  ANNOUNCEMENT INFO.;　Carbonyl 2018 Meeting, 2018, 7, 17-20
  AUTHOR;　Matsumoto A, Ito S, Hara T, Wakamatsu K, Suzuki T, Abe Y, Shimanoe C, Yuzuriha t, Yoshimori C, Muto T, Endo K, Hara M, Ichiba M, Vasiliou V, Song BJ, Fujita M
  
• A novel phenotype of ALDH2 polymorphism: drinking-induced skin pigmentation;　2017
  ANNOUNCEMENT INFO.;　IPCC(The International Pigment Cell Conference )2017, 2017, 8, 26-30
  AUTHOR;　Matsumoto A, Hara T, Shimanoe C, Yuzuriha T, Yoshimori C, Muto T, Endo K, Hara M, Ichiba M, Konakahara T, Yajima Y, Vasiliou V, Song BJ, Fujita M
  
• Significance of defective polymorphism of aldehyde dehydrogenase 2 gene (ALDH2) in prenatal toxicology;　2016
  ANNOUNCEMENT INFO.;　5th Conference on Prenatal Programming and Toxicity (pptoxV), 2016, 11, 13-16
  AUTHOR;　Matsumoto A
  
• Single-dose ethanol administration downregulates expression of cytochrome p450 2E1 mRNA in aldehyde dehydrogenase 2 knockout mice.;　2008/10
  ANNOUNCEMENT INFO.;　2nd World Conference on Magic Bullets (Ehrlich II). N�rnberg, Germany.
  AUTHOR;　Matsumoto A, Kawamoto T, Isse T, Oyama T, Ichiba M.
  
• ALDH2 transgenic knockout mice dislike alcohol drinking and receive more severe acetaldehyde toxicity.;　2007
  ANNOUNCEMENT INFO.;　11th congress of Eueopean Society for Biomedical Research on Alcoholism
  AUTHOR;　Isse T, Kitagawa K, Matsuda T, Matsumoto A, Oyama T, Kawamoto T
  

Review Articles

• Ethanol Metabolism and Melanoma ;　2023/02
  ANNOUNCEMENT INFO.;　Cancers (Basel), 15, 4, 1258
  AUTHOR;　*Zhai Z, Yamauchi T, Shangraw S, Hou V, Matsumoto A, Fujita M
  
• The Bidirectional Effect of Defective ALDH2 Polymorphism and Disease Prevention.;　2019/07
  ANNOUNCEMENT INFO.;　Adv Exp Med Biol. , 1193, 69-87
  AUTHOR;　Matsumoto A.
  
• Award Article Importance of an Aldehyde Dehydrogenase 2 Polymorphism in Preventive Medicine;　2018/01
  ANNOUNCEMENT INFO.;　Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 73, 1, 9-20
  AUTHOR;　Akiko MATSUMOTO
  
• Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis.;　2018
  ANNOUNCEMENT INFO.;　Adv Exp Med Biol. , 1032, 37-53
  AUTHOR;　*Chen Y, Han M, Matsumoto A, Wang Y, Thompson DC, Vasiliou V.
  
• Roles of defective ALDH2 polymorphism on liver protection and cancer development.;　2016
  ANNOUNCEMENT INFO.;　Environ Health Prev Med, 21, 6, 395-402
  AUTHOR;　Matsumoto A, Thompson DC, Chen Y, Kitagawa K and Vasiliou V
  
• Expression of cytochrome P450 in non-small cell lung cancer.;　2008/05
  ANNOUNCEMENT INFO.;　Front Biosci., 1, 13, 5787-5793
  AUTHOR;　Oyama T, Sugio K, Isse T, Matsumoto A, Nose N, Uramoto H, Nozoe T, Morita M, Kagawa N, Osaki T, Muto M, Yasumoto K, Kawamoto T.
  

Invited Lecture, Special Lecture

• EL2-01.Importance of ALDH2 polymorphism rs671 in public health and medicine;　2022
  ANNOUNCEMENT INFO.;　The 92nd Annual Meeting of the Japanese Society for Hygiene, 2022, 3,21-23(Live streaming), 2022, 3,21- 4,19(On-demand), Educational Lecture 2
  AUTHOR;　Akiko Matsumoto
  
• Hepatocyte necrosis is inhibited in ethanol administered transgenic mice lacking aldehyde dehydrogenase 2 activit;　2006
  ANNOUNCEMENT INFO.;　the 8th International Symposium of Aldh2 Knockout Mouse Research
  AUTHOR;　Akiko Matsumoto, Masayoshi Ichiba, Katsumaro Tomokouni