Detailed Information

Research Field/Keywords for Research Field

• Neurology Rehabilitation science/

Education

• 1999/03, Graduated

Employment Experience

• 1999/05 - 2001/04
• 2001/04 - 2001/05
• 2001/06 - 2003/05
• 2003/06 - 2003/09
• 2003/10 - 2004/05 University Hospital, Faculty of Medicine, Saga University
• 2004/06 - 2005/05
• 2005/06 - 2006/04 University Hospital, Faculty of Medicine, Saga University
• 2006/05 - 2007/03 Research Associate, University Hospital, Faculty of Medicine, Saga University
• 2007/04 - 2012/07 Assistant Professor, University Hospital, Faculty of Medicine, Saga University
• 2012/07 -  *  Assistant Professor, University Hospital, Faculty of Medicine, Saga University

Field of Specialization

• Neurology

Research Topics and Results

• Painless thyroiditis-induced cerebral infarction in a case of Moyamoya syndrome 2023/04
• Intracranial Myeloid Sarcoma Mimicking Hypertensive Intracerebral Hemorrhage 2023/02
• CASE REPORT Immune dysregulation syndrome with CTLA4 mutation showing multiple central nervous system lesions 2022/05
• SARS-CoV-2-related Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease: A Case Report and Literature Review 2022/04
• Associations for progression of cerebral small vessel burden in healthy adults: Seven-year follow-up study of the Kashima Scan Study, 2022
• Associations for progression of cerebral small vessel burden in healthy adults: the Kashima Scan Study 2022
• Paradoxical brain embolism due to a popliteal venous aneurysm after minor orthopedic surgery in a 19-year-old man with patent foramen ovale: A case report  2021/07
• Meta-iodobenzylguanidine myocardial scintigraphy in Perry disease  2021/02
• Total small vessel disease score and cerebro-cardiovascular events in healthy adults: The Kashima scan study 2020/12
• Subclinical acute Ischemic lesions and cerebrospinal fluid profiles in intracerebral hemorrhage: HAGAKURE STUDY 2020/11
• Total Small Vessel Disease Score among Ischemic Stroke Subtypes: HAGAKURE study 2020/11
• Synergistic effect of hypertension and smoking on the total small vessel disease score in healthy individuals: the Kashima scan study. 2019/11
• Parkinsonism Relating to Intoxication with Glyphosate. 2019/07
• Total small vessel disease score in neurologically healthy Japanese adults in the Kashima Scan Study  2018
• Duplication and deletion upstream of LMNB1 in autosomal dominant adult-onset leukodystrophy. 2018
• Paradoxical brain embolism due to a popliteal venous aneurysm after minor orthopedic surgery in a 19-year-old man with patent foramen ovale: A case report. 2018
• Total small vessel disease score and subsequent crebrocardivasucular events in neurologically healthy adults: 6.5 years follow-up in the Kashima Scan Study  2018
• Hypertension, Amyloid, and aGe Associated Kaleidoscopic brain lesions on CT/MRI Undertaken with stroke REgistry (HAGAKURE): rationale and study protocol.  2018
• Total small vessel disease score and subsequent cerebrocardivasucular events in neurologically healthy adults: 6.5 years follow-up in the Kashima Scan Study  2018
• Thrombolysis-related multiple lobar hemorrhages in cerebral amyloid angiopathy with extensive strictly lobar cerebral microbleeds 2017
• Validation study for the Japanese version of the Informant Questionnaire on Cognitive Decline on the Elderly (IQCODE-J). 2017
• Investigation of clinical course in amyotrophic lateral sclerosis with surgical interventions to prevent aspiration pneumonia. 2017
• LMNB1-related autosomal dominant leukodystrophy: genetic and clinical studies of three Japanese families 2017
• Worsening cervical epidural hamatoma after tissue plasminogen activator administration for stroke like symptoms 2016
• Basal Ganglia Cerebral Microbleeds and Global Cognitive Function: The Kashima Scan Study. 2015
• The concept of “total small vessel disease score” in healthy adults: validation in the Kashima Scan Study. 2015
• Norms of the Mini-Mental state Examination for Japanese subjects that underwent comprehensive brian examinations: the Kashima Scan Study. 2014
• Topography and associations of perivascular spaces in healthy adults: the Kashima scan study.  2014
• Basal Ganglia Cerebral Microbleeds and Global Cognitive Function: The Kashima Scan Study. 2014
• Topography of enlarged Perivascular Spaces and Cerebral Microbleeds in adults without neurological disorder - the population-based Kashima Scan Study - 2014
• Topography of perivascular spaces in neurologically healthy adults: the Kashima scan study 2014
• Adult case with isolated complex III deficiency of the mitochondrial respiratory chain presenting acute encephalopathy 2014
• Immunopathological significance of ovarian teratoma in patients with anti-N-methyl-D-aspartate receptor encephalitis 2013
• Stroke scale items associated with neurologic deterioration within 24 hours after recombinant tissue plasminogen activator therapy. 2013
• Immunopathological significance of ovarian teratoma in patients with anti-N-methyl-D-aspartate receptor encephalitis 2013
• Is multiple sclerosis an autoimmune disease? 2012
• A cese of Marinesco-Sjogren syndrome: MRI observations of skeltal muscles, bone metabolism, and treatment with testosterone and risedronate. 2011
• Marked cerebral atrophy is correlated with kidney dysfunction in nondisabled adults. 2010
• Interferon therapy-responsive brain metabolic abnormalities in a case of adult-onset subacute sclerosing panencephalitis evaluated by1H-MRS analysis. 2003

Books

• alpha Pix enhances mutant huntingtin aggregation.;　2009
  ANNOUNCEMENT INFO.;　J Neurol Sci. 2010 Mar 15;290(1-2):80-5. Epub 2009 Dec 6.
  AUTHOR;　Eriguchi M, Mizuta H, Luo S, Kuroda Y, Hara H, Rubinsztein DC
  

Original Articles

• Meta-iodobenzylguanidine myocardial scintigraphy in Perry disease ;　2021/02
  ANNOUNCEMENT INFO.;　Parkinsonism Relat Disord, 83, 49-53
  AUTHOR;　*Takayasu Mishima, Shinsuke Fujioka, Kenya Nishioka, Yuanzhe Li, Kazunori Sato, Hideki Houzen, Ichiro Yabe, Kazutaka Shiomi, Makoto Eriguchi, Hideo Hara, Nobutaka Hattori, Yoshio Tsuboi
  
• Total small vessel disease score and cerebro-cardiovascular events in healthy adults: The Kashima scan study;　2020/12
  ANNOUNCEMENT INFO.;　Int J Stroke, 15, 9, 973-979
  AUTHOR;　Kohei Suzuyama, Yusuke Yakushiji, Atsushi Ogata, Masashi Nishihara, Makoto Eriguchi, Atsushi Kawaguchi, Tomoyuki Noguchi, Junko Nakajima, Hideo Hara
  
• Synergistic effect of hypertension and smoking on the total small vessel disease score in healthy individuals: the Kashima scan study.;　2019/11
  ANNOUNCEMENT INFO.;　Hypertens Res. , 42, 11, 1738-1744
  AUTHOR;　○Hara M, Yakushiji Y, Suzuyama K, Nishihara M, Eriguchi M, Noguchi T, Nishiyama M, Nanri Y, Tanaka J, Hara H
  
• Total small vessel disease score in neurologically healthy Japanese adults in the Kashima Scan Study ;　2018
  ANNOUNCEMENT INFO.;　Intern Med. , 57, 2, 189-196
  AUTHOR;　Yakushiji Y, Charidimou A, Noguchi T, Nishihara M, Eriguchi M, Nanri Y, Kawaguchi A Hirotsu T, Werring DJ, Hara H
  
• Duplication and deletion upstream of LMNB1 in autosomal dominant adult-onset leukodystrophy.;　2018
  ANNOUNCEMENT INFO.;　Neurol Genet. , 4, 6, e292
  AUTHOR;　*Mezaki N, Miura T, Ogaki K, Eriguchi M, Mizuno Y, Komatsu K, Yamazaki H, Suetsugi N, Kawajiri S, Yamasaki R, Ishiguro T, Konno T, Nozaki H, Kasuga K, Okuma Y, Kira JI, Hara H, Onodera O, Ikeuchi T.
  
• Basal Ganglia Cerebral Microbleeds and Global Cognitive Function: The Kashima Scan Study.;　2015
  ANNOUNCEMENT INFO.;　J Stroke Cerebrovasc Dis., 24, 2, 431-9
  AUTHOR;　Yakushiji Y, Noguchi T, Charidimou A, Eriguchi M, Nishihara M, Hara M, Nanri Y, Horikawa E, Nishiyama M, Werring DJ, Hara H.
  
• Norms of the Mini-Mental state Examination for Japanese subjects that underwent comprehensive brian examinations: the Kashima Scan Study.;　2014
  ANNOUNCEMENT INFO.;　Intern Med. , 53, 21, 2447-53
  AUTHOR;　Yakushiji Y, Horikawa E, Eriguchi M, Nanri Y, Nishihara M, Hirotsu T, Hara H.
  
• Topography and associations of perivascular spaces in healthy adults: the Kashima scan study. ;　2014
  ANNOUNCEMENT INFO.;　Neurology. , 83, 23, 2116-23
  AUTHOR;　Yakushiji Y, Charidimou A, Hara M, Noguchi T, Nishihara M, Eriguchi M, Nanri Y, Nishiyama M, Werring DJ, Hara H.
  
• Basal Ganglia Cerebral Microbleeds and Global Cognitive Function: The Kashima Scan Study.;　2014
  ANNOUNCEMENT INFO.;　J Stroke Cerebrovasc Dis., 24, 2, 431-9
  AUTHOR;　Yakushiji Y, Noguchi T, Charidimou A, Eriguchi M, Nishihara M, Hara M, Nanri Y, Horikawa E, Nishiyama M, Werring DJ, Hara H.
  
• Immunopathological significance of ovarian teratoma in patients with anti-N-methyl-D-aspartate receptor encephalitis;　2013
  ANNOUNCEMENT INFO.;　Europian neurology, 71, 1-2, 42-48
  AUTHOR;　Emi Tabata, Masanori Masuda,Makoto Eriguchi, Masatoshi Yokoyama, Yoshiyuki Takahashi, Keiko Tanaka, Motohiro Yukitake, Etuo Horikawa,Hideo Hara, MD, PhD.
  
• Stroke scale items associated with neurologic deterioration within 24 hours after recombinant tissue plasminogen activator therapy.;　2013
  ANNOUNCEMENT INFO.;　J Stroke Cerebrovasc Dis., 22, 7, 1117-1124
  AUTHOR;　〇Nanri Y, Yakushiji Y, Hara M, Eriguchi M, Okada R, Yukitake M, Hara H.
  
• A cese of Marinesco-Sjogren syndrome: MRI observations of skeltal muscles, bone metabolism, and treatment with testosterone and risedronate.;　2011
  ANNOUNCEMENT INFO.;　Intern Med　, 50, 2, 145-149
  AUTHOR;　Fujitake J, Komatsu Y, Hataya Y, Nishikawa A, Eriguchi M, Mizuta H, Hayashi M
  
• Marked cerebral atrophy is correlated with kidney dysfunction in nondisabled adults.;　2010
  ANNOUNCEMENT INFO.;　Hypertens Res　, 33, 12, 1232-1237
  AUTHOR;　Yakushiji Y, Nanri Y, Hirotsu T, Nishihara M, Hara M, Nakajima J,Eriguchi M, Nishiyama M, Hara H, Node K
  
• Identification of a new homozygous frameshift insertion mutation in　the SIL1 gene in 3 Japanese patients with Marinesco-Sjogren syndrome. 　　;　2008
  ANNOUNCEMENT INFO.;　J Neurol Sci., 270, 197-200
  AUTHOR;　Eriguchi M○, Mizuta H, Kurohara K, Fujitake J, Kuroda Y.
  
• Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness;　2008
  ANNOUNCEMENT INFO.;　Annals of neurology, 60, 5, 597-602
  AUTHOR;　Murakami T,Hayashi YK,Noguchi S,Ogawa M,Nonaka I,Tanabe Y,Ogino M,Takada F,Kotooka N,Campbell KP,Osawa M,Nishino I
  
• Interferon therapy-responsive brain metabolic abnormalities in a case of adult-onset subacute sclerosing panencephalitis evaluated by1H-MRS analysis.;　2003
  ANNOUNCEMENT INFO.;　J Neurol Sci, 207, 59-63
  AUTHOR;　Takashima H,Eriguchi M,Nakamura T,Satoh J,Kuroda Y,Udono H,Uchino A
  

Material, Commentary, Editorials, Research Report, A Comprehensive Journal Articles

• Painless thyroiditis-induced cerebral infarction in a case of Moyamoya syndrome;　2023/04
  ANNOUNCEMENT INFO.;　Acta Neurol Belg
  AUTHOR;　Ikeda S, Tsutsumi M, Hisatomi A, Takayanagi H, Eriguchi M
  
• Intracranial Myeloid Sarcoma Mimicking Hypertensive Intracerebral Hemorrhage;　2023/02
  ANNOUNCEMENT INFO.;　Intern Med
  AUTHOR;　Ikeda S, Tsutsumi M, Fujita M, Okamoto S, Eriguchi M, Hara H
  
• CASE REPORT Immune dysregulation syndrome with CTLA4 mutation showing multiple central nervous system lesions;　2022/05
  ANNOUNCEMENT INFO.;　Clin Exp Neuroimmunol, 13, 2, 116-120
  AUTHOR;　Makoto Eriguchi, Hiroo Katsuya, Keisuke Kidoguchi, Hiroshi Ureshino, Nishi Masanori, Masashi Nishihara, Motoshi Sonoda, Masataka Ishimura, Shinya Kimura, Hideo Hara
  
• Paradoxical brain embolism due to a popliteal venous aneurysm after minor orthopedic surgery in a 19-year-old man with patent foramen ovale: A case report ;　2021/07
  ANNOUNCEMENT INFO.;　J Orthop Sci, 26, 4, 714-718
  AUTHOR;　○Motoki Sonohata, Makoto Eriguchi, Atsushi Ogata, Kazuki Muranaka, Masaaki Mawatari
  
• Parkinsonism Relating to Intoxication with Glyphosate.;　2019/07
  ANNOUNCEMENT INFO.;　Intern Med. , 58, 13, 1935-1938
  AUTHOR;　Eriguchi M, Iida K, Ikeda S, Osoegawa M, Nishioka K, Hattori N, Nagayama H, Hara H.
  
• Paradoxical brain embolism due to a popliteal venous aneurysm after minor orthopedic surgery in a 19-year-old man with patent foramen ovale: A case report.;　2018
  ANNOUNCEMENT INFO.;　J Orthop Sci.
  AUTHOR;　○Sonohata M, Eriguchi M, Ogata A, Muranaka K, Mawatari M.
  
• Thrombolysis-related multiple lobar hemorrhages in cerebral amyloid angiopathy with extensive strictly lobar cerebral microbleeds;　2017
  ANNOUNCEMENT INFO.;　Intern Med., 56, 14, 1907-1910
  AUTHOR;　Makoto Eriguchi, Yusuke Yakushiji, Jun Tanaka Masashi Nishihara, Hideo Hara
  
• Worsening cervical epidural hamatoma after tissue plasminogen activator administration for stroke like symptoms;　2016
  ANNOUNCEMENT INFO.;　Spine (Phila Pa 1976)., 41, 7, E437-40
  AUTHOR;　○Morimoto T, Yoshihara T, Yakushiji Y, Eriguchi M, Hara H, Sonohata M, Mawatari M
  
• Is multiple sclerosis an autoimmune disease?;　2012
  ANNOUNCEMENT INFO.;　Autoimmune Dis.
  AUTHOR;　Wootla B, Eriguchi M, Rodriguez M
  
• Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness;　2007
  ANNOUNCEMENT INFO.;　Annals of neurology, 60, 5
  AUTHOR;　Mizuta H,Kurohara K,Kosugi M,Yakushiji Y,Okada R, Yukitake M, Hasegawa Y,Yamaguchi S,Kuroda Y
  
• 3-Methylglutaconic aciduria typeI causes leukoencephalopathy of adult onset;　2006
  ANNOUNCEMENT INFO.;　, 67, 10
  AUTHOR;　Mizuta H,Kurohara K,Kosugi M,Yakushiji Y,Okada R, Yukitake M, Hasegawa Y,Yamaguchi S,Kuroda Y
  
• Gyral abnormalities in the early stage of superior sagittal sinus thrombosis;　2005
  ANNOUNCEMENT INFO.;　European radiology, 15, 8
  AUTHOR;　Uchino A,Sawada A,Takase Y,Nishihara M,Kurohara K,Kuroda Y,Kudo S
  

General Lectures

• Associations for progression of cerebral small vessel burden in healthy adults: Seven-year follow-up study of the Kashima Scan Study,;　2022
  ANNOUNCEMENT INFO.;　The 10th Korea-Japan Joint Stroke Conference (KJJSC2022 Osaka)(VIRTUAL), 2022, 9,17-18(Live streaming), 2022, 9,17-10,31(On-demand)
  AUTHOR;　Toshihiro Ide, Yusuke Yakushiji, Kohei Suzuyama, Atsushi Ogata, Masashi Nishihara, Makoto Eriguchi, Akiko Matsumoto, Megumi Hara, Hideo Hara
  
• Associations for progression of cerebral small vessel burden in healthy adults: the Kashima Scan Study;　2022
  ANNOUNCEMENT INFO.;　ESOC 2022(hybrid event), 2022, 5, 4-6(On-site+On-line), 2022, 5, 4-8, 5(on-demand)
  AUTHOR;　Toshihiro Ide, Yusuke Yakushiji, Kohei Suzuyama, Atsushi Ogata, Masashi Nishihara, Makoto Eriguchi, Akiko Matsumoto, Hideo Hara
  
• Subclinical acute Ischemic lesions and cerebrospinal fluid profiles in intracerebral hemorrhage: HAGAKURE STUDY;　2020/11
  ANNOUNCEMENT INFO.;　ESO-WSO Conference 2020 (Virtual Conference), 2020,11, 7-9
  AUTHOR;　Yoshikawa M, Yakushiji Y, Tanaka J, Ogata A, Nishihara M, Eriguchi M, Suzuyama K, Nagaishi Y, Mizoguchi M, Shichijo C, Ide T, Katsuki Y, Kawamoto K, Abe T, Hara H
  
• Total Small Vessel Disease Score among Ischemic Stroke Subtypes: HAGAKURE study;　2020/11
  ANNOUNCEMENT INFO.;　ESO-WSO Conference 2020 (Virtual Conference), 2020,11, 7-9
  AUTHOR;　Iida K, Yakushiji Y, Tanaka J, Nishihara M, Eriguchi M, Suzuyama K, Shichijo C, Nagaishi Y, Megumi M, Suetsugu N, Ide T, Yoshikawa M, Hoshino Y, Katsuki Y, Hideo H
  
• Total small vessel disease score and subsequent crebrocardivasucular events in neurologically healthy adults: 6.5 years follow-up in the Kashima Scan Study ;　2018
  ANNOUNCEMENT INFO.;　ESOC 2018 -4th European Stroke Organization Conference, 2018, 5,16-18
  AUTHOR;　Suzuyama K, Yakushiji Y, Nishihara M, Eriguchi M, Noguchi T, Nakajima J, Nanri Y, Tanaka J, Hara H
  
• Hypertension, Amyloid, and aGe Associated Kaleidoscopic brain lesions on CT/MRI Undertaken with stroke REgistry (HAGAKURE): rationale and study protocol. ;　2018
  ANNOUNCEMENT INFO.;　ESOC 2018 -4th European Stroke Organization Conference, 2018, 5,16-18
  AUTHOR;　Yakushiji Y, Tanaka J, Nishihara M, Ogata A, Suzuyama K, Eriguchi M, Irie H, Abe T, Hara H, on behalf of the HAGAKURE Investigators.
  
• Total small vessel disease score and subsequent cerebrocardivasucular events in neurologically healthy adults: 6.5 years follow-up in the Kashima Scan Study ;　2018
  ANNOUNCEMENT INFO.;　ESOC 2018 -4th European Stroke Organization Conference, 2018, 5,16-18
  AUTHOR;　Suzuyama Kohei, Yusuke Yakushiji, Masashi Nishihara, Makoto Eriguchi, Tomoyuki Noguchi, Junko Nakajima, Yusuke Nanri, Jun Tanaka, and Hideo Hara
  
• Validation study for the Japanese version of the Informant Questionnaire on Cognitive Decline on the Elderly (IQCODE-J).;　2017
  ANNOUNCEMENT INFO.;　XXIII World Congress of Neurology (WCN2017), 2017. 9.16-21
  AUTHOR;　Mizoguchi M, Yakushiji Y, Eriguchi M, Kosugi M, Sakamoto M, Horikawa E, Hara H
  
• Investigation of clinical course in amyotrophic lateral sclerosis with surgical interventions to prevent aspiration pneumonia.;　2017
  ANNOUNCEMENT INFO.;　XXIII World Congress of Neurology (WCN2017), 2017. 9.16-21
  AUTHOR;　Eriguchi M, Yakushiji Y, Suzuyama K, Maeda K, Mizoguchi M, Tanaka J, Monji M, Kuratomi Y, Hara H
  
• LMNB1-related autosomal dominant leukodystrophy: genetic and clinical studies of three Japanese families;　2017
  ANNOUNCEMENT INFO.;　2017 AAN Annual Meeting, 2017.4.22-28
  AUTHOR;　*N. Mezaki, T. Miura, K. Ogaki, M.Eriguchi, H. Yamazaki, Y.Komatsu, N. Ono, S.Kawajiri, H. Nozaki, K. Kasuga, Y. Okuma, H. Hara, O. Onodera, T. Ikeuchi
  
• The concept of “total small vessel disease score” in healthy adults: validation in the Kashima Scan Study.;　2015
  ANNOUNCEMENT INFO.;　The European Stroke Organisation Conference 2015 (ESOC2015), 2015 4. 17-19
  AUTHOR;　Yakushiji Y, Charidimou A, Hara M, Eriguchi M, Noguchi T, Nishihara M, Nanri Y, MD, Nishiyama M, Werring D.J., Horikawa E, Hara H
  
• Topography of enlarged Perivascular Spaces and Cerebral Microbleeds in adults without neurological disorder - the population-based Kashima Scan Study -;　2014
  ANNOUNCEMENT INFO.;　The 23rd European Stroke Conference., 2014, 5, 6-9
  AUTHOR;　Yakushiji　Y, Charidimou A, Werring D.J, Noguchi T, Nishihara M, Nanri Y, Eriguchi M, Nakajima J, Hara H
  
• Topography of perivascular spaces in neurologically healthy adults: the Kashima scan study;　2014
  ANNOUNCEMENT INFO.;　4th International CAA Conference in London, 2014, 9, 18-20
  AUTHOR;　Yakushiji Y, Charidimou A, Hara M, Noguchi T, Nishihara M, Eriguchi M, Nanri Y, MD, Nishiyama M, Werring D.J., Hara H
  
• Adult case with isolated complex III deficiency of the mitochondrial respiratory chain presenting acute encephalopathy;　2014
  ANNOUNCEMENT INFO.;　Joint Congress of European Neurology, 2014.5.31-6.3
  AUTHOR;　M Eriguchi, M.Yukitake, T.Oka, Y.Shigematu, H.Sugie, I.Nishino, K.Murayama, H.Hara
  
• Immunopathological significance of ovarian teratoma in patients with anti-N-methyl-D-aspartate receptor encephalitis;　2013
  ANNOUNCEMENT INFO.;　World Congress of Neurology - Wien 2013, Saturday 21st September 2013 to Thursday 26th September 2013
  AUTHOR;　Emi Tabata, Masanori Masuda,Makoto Eriguchi, Masatoshi Yokoyama, Yoshiyuki Takahashi, Keiko Tanaka, Motohiro Yukitake, Etuo Horikawa,Hideo Hara, MD, PhD.
  
• New concept of walker for walking disorders in Parkinson’s disease patients.;　2008
  ANNOUNCEMENT INFO.;　th Mediterranean Congress of Physical and Rehabilitation Medicine.
  AUTHOR;　○Asami T. Eriguch M Akiyama N, Kodama K, Yamanouchi N. and Asami A
  

Review Articles

• SARS-CoV-2-related Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease: A Case Report and Literature Review;　2022/04
  ANNOUNCEMENT INFO.;　Intern Med, 61, 8, 1253-1258
  AUTHOR;　Toshihiro Ide, Takeru Kawanami, Makoto Eriguchi, Hideo Hara