Detailed Information

Research Field/Keywords for Research Field

• Orthopaedics,Tissue Engineering, Regenerative medicine, Bio 3D Printing, BioFabrication

Education

• 1997/03, Kyushu university, Department of Medicine, School of Medicine, Graduated
• 2005/03, Graduate School, Kyushu university, Medical Science, Orthopedic Surgery, Doctor Course, Completed

Employment Experience

• 1997/05 - 1998/06 Fukuoka Red Cross hospital
• 1998/07 - 1999/05 Kyushu central hospital
• 1999/06 - 1999/11 Kyushu university hospital
• 1999/12 - 2000/06 Kyushu Medical Center
• 2000/07 - 2001/03 Miyazaki prefectural hospital
• 2005/04 - 2006/10 Kyushu university hospital
• 2006/10 - 2009/09 Assistant Professor Kyushu university hospital
• 2009/09 - 2010/03 Professor, Advanced Systems Control Engineering, Graduate School of Science and Engineering, Saga University
• 2010/04 - 2015/03 Professor, Advanced Technology Fusion, Graduate School of Science and Engineering, Saga University
• 2015/04 -  *  Professor, Department of Regenerative Medicine and Biomedical Engineering, Faculty of Medicine, Saga University
• 2019/04 -  Director in General, Center for Regenerative medicine resarch, Saga University

Field of Specialization

• Orthopaedic surgery, General surgery, Cardiovascular surgery, Biomedical engineering

Membership in Academic Societies

• International cartilage repair society, Tissue Engineering and Regenerative Medicine International Society

Research Topics and Results

• Scaffold-free bone-like 3D structure established through osteogenic differentiation from human gingiva-derived stem cells 2024/07
• Creating 3D constructs with cranial neural crest-derived cell lines using a bio-3D printer 2024/06
• Xenograft of bio-3D printed scaffold-free cartilage constructs for regeenration of articular cartilage in immunodeficient pigs 2024/06
• Scaffold-free constructs comprising adipose tissue-derived mesenchymal stem cells produced by a bio-3D printer promote bone-tendon healing after anterior cruciate ligament reconstruction in rabbit models. 2024/06
• Regeneration of the patellar tendon using scaffold-free 3D constructs consisted of adipose tissue-derived mesenchymal stem cells in rabbits 2024/06
• Three-Dimensional Bio-Printed Tubular Tissue Using Dermal Fibroblast Cells as a New Tissue-Engineered Vascular Graft for Venous Replacement 2024/05
• Scaffold-free cartilage constructs for large chondral defects fabricated using bio-3D printer 2023/11
• Scaffold-free 3D osteogenic construct composed of human bone marrow-derived mesenchymal stem cells and human umbilical vein endothelial cells 2023/11
• Scaffold-free Bio-3D Printing for Solid organ fabrication 2023/11
• バイオ3Ｄプリンタを用いた臓器再生への取り組み 2023/11
• 臓器再生を目指したバイオ3Dプリンタの開発とその応用 2023/11
• バイオ3Ｄプリンタを用いた臓器再生への取り組み 2023/10
• バイオ３Dプリンタを用いた臓器再生 2023/09
• Special Issue: Biofabrication with Spheroid and Organoid Materials 2023/07
• Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique 2023/07
• Editorial Board, Special Issue: Biofabrication with Spheroid and Organoid Materials, Engineered biomaterials to guide spheroid formation, function, and fabrication into 3D tissue constructs, 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration, 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration, Bioprinting of hair follicle germs for hair regenerative medicine, All-aqueous printing of viscoelastic droplets in yield-stress fluids, Hybrid spheroid microscaffolds as modular tissue units to build macro-tissue assemblies for tissue engineering, Hyaluronic acid methacrylate/pancreatic extracellular matrix as a potential 3D printing bioink for constructing islet organoids, Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique, Engineering bone-forming biohybrid sheets through the integration of melt electrowritten membranes and cartilaginous microspheroids, Mathematical and computational models in spheroid-based biofabrication, Building a tissue: Mesenchymal and epithelial cell spheroids mechanical properties at micro- and nanoscale, 3D microengineered vascularized tumor spheroids for drug delivery and efficacy testing, Bone beads enveloped with vascular endothelial cells for bone regenerative medicine, Bone beads enveloped with vascular endothelial cells for bone regenerative medicine, Corrigendum to ‘3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration’ [Acta Biomaterialia (2022)] 2023/07
• Scaffold-free human vascular calcification model using a bio-three-dimensional printer 2023/07
• Special Issue: Biofabrication with Spheroid and Organoid Materials 2023/07
• Scaffold-free human vascular calcification model using a bio-three-dimensional printer 2023/06
• Enhanced chondrogenic differentiation of iPS cell-derived mesenchymal stem/stromal cells via neural crest cell induction for hyaline cartilage repair 2023/05
• バイオ３Dプリンタを用いた骨/軟骨組織再生の試み 2023/05
• CULTURE APPARATUS FOR USE IN STUDIES ON DRUG DEVELOPMENT 2023/02
• Development of Beat Analysis Software for the Non-invasive Evaluation of Cardiac Constructs Fabricated with a Three-dimensional Bioprinter 2023
• 人工血管－TEVGの臨床開発－ 2023
• Nerve regeneration using the Bio 3D nerve conduit fabricated with spheroids  2022/12
• 3D Printing in Nephrology 2022/10
• Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique  2022/10
• The Kenzan Method: from Bench to Bedside 2022/09
• Kenzan Method from Academia to Industry 2022/09
• Involvement of the PI3K/AKT Pathway in the Formation and Fusion of Spheroids Derived from Human Dermal Fibroblast for Tissue Engineering Technology 2022/08
• METHOD FOR MANUFACTURING LUMINAL STRUCTURE 2022/08
• Regeneration of Trachea and Esophagus by Scaffold-Free Structure, Using Bio-3D Printer 2022/04
• Successful use of bio plugs for delayed bronchial closure after pneumonectomy in experimental settings 2022/03
• Bio-3D printing of scaffold-free osteogenic and chondrogenic constructs using rat adipose-derived stromal cells  2022/02
• Osteochondral regeneration of the femoral medial condyle by using a scaffold-free 3D construct of synovial membrane-derived mesenchymal stem cells in horses  2022/01
• Scaffold-Free Tubular Engineered Heart Tissue From Human Induced Pluripotent Stem Cells Using Bio-3D Printing Technology in vivo 2022/01
• PROGRESS AND FUTURE PROSPECTS OF CLINICAL RESEARCH ON SCAFFOLD-FREE BIOFABRICATION BY THE KENZAN METHOD 2022
• Establishment of large canine hepatocyte spheroids by mixing vascular endothelial cells and canine adipose-derived mesenchymal stem cells 2021/12
• Bio-3D printing iPSCs-derived human chondrocytes for articular cartilage regeneration 2021/08
• Scaffold-based and scaffold-free cardiac constructs for drug testing  2021/07
• History of the Kenzan method:from bemch to bedside 2021/06
• Mechanism of Peripheral Nerve Regeneration Using a Bio 3D Conduit Derived from Normal Human Dermal Fibroblasts  2021/05
• Bile duct reconstruction using scaffold-free tubular constructs created by Bio-3D printer  2021/02
• Regular Papers Study on Pipetting Motion Optimization of Automatic Spheroid Culture System for Spheroid Formation 2021/02
• Kenzan Method for Scaffold-Free Biofabrication 2021
• Long-Term Outcome of Sciatic Nerve Regeneration Using Bio3D Conduit Fabricated from Human Fibroblasts in a Rat Sciatic Nerve Model  2021
• Fabrication of Cardiac Constructs Using Bio-3D Printer  2021
• Progress and future prospects of clinical research on scaffold-free Biofabricantion by the Kenzan method 2021
• The early effects of scaffold-free constructs of adipose tissue-derived mesenchymal stem cells on tendon-bone healing after anterior cruciate ligament reconstruction in a rabbit model 2021
• Tendon/ligament regeneration using a scaffold-free biofabricated 3D construct of Autologous adipose tissue-derived mesenchymal stem cells in rabbits 2021
• Correction: Cryopreservation method for spheroids and fabrication of scaffold-free tubular constructs  2020/11
• Correction: Fabrication of scaffold-free tubular cardiac constructs using a Bio-3D printer 2020/11
• Mechanism of Peripheral Nerve Regeneration Using a Bio 3D Conduit Derived from Normal Human Dermal Fibroblasts 2020/09
• Scaffold-Free Bio-3D Printing Using Spheroids as "Bio-Inks" for Tissue (Re-)Construction and Drug Response Tests. 2020/08
• Osteochondral regeneration using scaffold-free constructs of adipose tissue-derived mesenchymal stem cells made by a bio three-dimensional printer with a needle-array in rabbits 2020/07
• Pre-clinical study of human cell-based vascular graft using a novel operational immunodeficient pig model 2020/07
• Pro-angiogenic scaffold-free Bio three-dimensional conduit developed from human induced pluripotent stem cell–derived mesenchymal stem cells promotes peripheral nerve regeneration 2020/07
• Drug Response Analysis for Scaffold-Free Cardiac Constructs Fabricated Using bio-3D Printer 2020/06
• Osteochondral Regeneration Using Adipose TissueDerived Mesenchymal Stem Cells 2020/05
• Human lung microvascular endothelial cells as potential alternatives to human umbilical vein endothelial cells in bio-3D-printed trachea-like structures. 2020/04
• Cryopreservation method for spheroids and fabrication of scaffold-free tubular constructs.　 2020/04
• A scaffold-free Bio 3D nerve conduit for repair of a 10-mm peripheral nerve defect in the rats 2020/02
• Bio 3D Conduits Derived from Bone Marrow Stromal Cells Promote Peripheral Nerve Regeneration 2020
• CULTURE APPARATUS FOR USE IN STUDIES ON DRUG DEVELOPMENT 2020
• METHOD FOR MANUFACTURING LUMINAL STRUCTURE 2020
• Ligament reconstruction using Scaffold-free Cell Construct produced by Bio Three-dimensional Printer. 2019/10
• Drug response of scaffold-free cardiac constructs fabricated using bio-3D printing 2019/10
• 2-Cl-C.OXT-A stimulates contraction through the suppression of phosphodiesterase activity in human induced pluripotent stem cell-derived cardiac organoids. 2019/07
• Scaffold-free Bio-3D printing for Solid organ fabricatio 2019/07
• Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes. 2019/05
• Histological evaluation of tendon formation using a scaffold-free three-dimensional-bioprinted construct of human dermal fibroblasts under in vitro static tensile culture  2019/05
• Correction: Regeneration of esophagus using a scaffold-free biomimetic structure created with bio-three-dimensional printing 2019/04
• Replacement of Rat Tracheas by Layered, Trachea-like, Scaffold-free Structures of Human Cells Using Bio-3D Printing System. 2019/04
• Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED):a promising new treatment in pediatric surgery  2019/04
• Regeneration of esophagus using a scaffold-free biomimetic structure created with bio-three-dimensional printing 2019/03
• A Scaffold-Free Allogeneic Construct From Adipose-Derived Stem Cells　Regenerates an Osteochondral Defect in a Rabbit Model 2019/02
• The Efficacy of a Scaffold-free Bio 3D Conduit Developed from Autologous Dermal Fibroblasts on Peripheral Nerve Regeneration in a Canine Ulnar Nerve Injury Model: A Preclinical Proof-of-Concept Study. 2019
• Scaffold-free ligament structures produced by using bio three-dimensional printer 2018/10
• Scaffold-free bio-3D printing for solid organ fabrication 2018/10
• Bioassembly of cell spheroids: moving towards the clinic. 2018/10
• Toward in vitro construction of iPSC-derived human heart-like tissus 2018/09
• Drug response of scaffold-free cardiac constructs fabricated using bio-3D printing 2018/09
• Ligament structures produced by using bio three-dimensional printer 2018/09
• Artificial trachea and esophagus using bio 3D printer 2018/09
• The efficacy of a Scaffold-free Bio 3D conduit developed from dermal fibroblasts on periheral nerve regeneration in a canine ulnar injury model 2018/09
• The KenZan method：from bench to bedside 2018/09
• Regeneration of diaphragm with bio-3D cellular patch 2018/06
• Osteochondral Regeneration Using A Scaffold-Free 3D-Construct of SM -Mscs In Horse 2018/04
• Scaffold-free trachea regeneration by tissue engineering with bio-three- dimensional printing 2018/04
• Scaffold-Free Bio-3D Printing for Solid Organ Fabrication 2018/03
• A definition of bioinks and their distinction from biomaterial inks 2018
• Fabrication of scaffold-free tubular cardiac constructs using a bio-3D printer. 2018
• The addition of human iPS cell-derived neural progenitors changes the contraction of human iPS cell-derived cardiac spheroids　 2018
• Osteochondral regeneration with a scaffold-free three-dimensional construct of adipose tissue-derived mesenchymal stromal cells in pigs. 2018
• Introduction of Scaffold-Free Bio 3D Printer for Organ Regeneration. 2017/11
• Scaffold-free Bio-3D Printing for Solid organ fabrication 2017/10
• Regenerative Medicine 2017/10
• In vivo and ex vivo methods of growing a liver bud through tissue connection 2017/10
• Development and therapeutic application of Scaffold-free 3D tissue and Organ fabrication by Bio-3D printer 2017/09
• 3D bioprinted scaffold-free blood vessels for clinical and research applications 2017/06
• Scaffold-Free Biofabrication 2017/06
• Principles of the ‘Kenzan’ method for robotic cell spheroid-based three-dimensional bioprinting. 2017/06
• Scaffold-free bio-3D printing for solid organ fabrication. 2017/05
• The efficacy of a scaffold-free bio 3D conduit developed from human fibroblasts on peripheral nerve regeneration in a rat sciatic nerve model. 2017/02
• Scaffold-free tissue-engineered allogenic adipose-derived stem cells promote meniscus healing. 2017/02
• Osteochondral regeneration using a scaffold-free construct of adipose tissue-derived mesenchymal stem cells made by bio three-dimensional printer with needle-array in pigs 2017
• Bio 3D printing scaffold-free blood vessels. 2016/12
• Scaffold-free bio-3D printing for solid organ fabrication. 2016/11
• Scaffold-free bio-3D printing for solid organ fabrication. 2016/11
• Fabrication of scaffold-free cardiac construct by bio ３D-printer. 2016/10
• Addition of human iPS-derived neural progenitors influences the contractile function of cardiac spheroids. 2016/10
• Bio 3D printed solid cartilage from iPSC-derived chondrocyte. 2016/09
• Osteochondral regeneration of the loading-bearing site using a scaffold-free 3D construct of swine AT-MSCs. 2016/09
• Osteochondral regeneration by implanting a scaffold-free construct of swine AT-MSCs using a bio 3D printer. 2016/09
• Scaffold-free Bio-3D printing for solid organ fabrication. 2016/06
• Scaffold-free 3D tissue & organ fabrication by bio-3D printer. 2016/03
• Scaffold-free 3D tissue & organ fabrication by bio-3D printer. 2016/03
• Scaffold-free 3D tissue & organ fabrication by bio-3D printer. 2016/03
• A new strategy for liver tissue fabrication and transplantation. 2016/02
• Development of a three-dimensional pre-vascularized scaffold-free contractile cardiac patch for treating heart disease. 2016/01
• The fabrication of scaffold free cardiomyocytes constructs by using Bio-3D printer. 2015/11
• Development of scaffold free 3D tissue & organ fabrication by bio-3D printer. 2015/11
• The effectiveness of using a bio-3D printer in the development of a scaffold-free regenerative vascular graft. 2015/09
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery. 2015/09
• Osteochondral regeneration using a scaffold free three-dimensional construct of swine adipose tissue-derived mesenchymal stem cells. 2015/09
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery. 2015/08
• Development of scaffold-free 3D tissue & organ fabrication by bio-3D printer. 2015/08
• MP19-17 Human urethra-engineered with human mesenchymal stem cell with maturation by rearrangement of cells for self-organization -newly developed scaffold-free three-dimensional bio-printer. 2015/04
• A preliminary study of osteochondral regeneration using a scaffold-free three-dimensional construct of porcine adipose tissue-derived mesenchymal stem cells. 2015/03
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery 2015/02
• Correction: Scaffold-Free Tubular Tissues Created by a Bio-3D Printer Undergo Remodeling and Endothelialization when Implanted in Rat Aortae. 2015
• 細胞培養用治具 2015
• Implantation of scaffold-free tubular tissue using a bio-3D printer augments vascular remodeling and endothelialization. 2014/11
• A new approach for 3D tissue & organ fabricatoin inspired from orthopedic surgery. 2014/11
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery. 2014/11
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery 2014/10
• Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells. 2014/10
• Multipotency of equine mesenchymal stem cells derived from synovial fluid. 2014/10
• In vitro fabrication of scaffold-free meniscus-like constructs using bio-3D Printer. 2014/07
• Three dimensional construct fabrication and mechanical pressure culture enhance. 2014/07
• A New Approach for 3D Tissue & Organ Fabrication Inspired from Orthopedic Surgery. 2014/07
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery. 2014/05
• Liver Tissue Spheroid 2014/03
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery 2013/11
• Construction of scaffold-free three dimensional liver tissue by spheroid fusion using the bio 3D printer. 2013/09
• Construction of scaffold-free three dimensional liver tissue by spheroid fusion using the bio 3D printer. 2013/09
• Osteochondral regeneration with scaffold free 3D-structure of swine adipose tissue-derived mesenchymal stem cells. 2013/09
• Construction of scaffold-free three dimensional liver tissue by spheroid fusion using the bio 3D printer. 2013/09
• Bio rapid prototyping project: Development of spheroid formation system for regenerative medicine. 2013/07
• Development of 3-dimensional prevascularized scaffold-free contractile cardiac patch for heart regeneration. 2013/04
• Development of 3-dimensional prevascularized scaffold-free contractile cardiac patch for heart regeneration. 2013/04
• Spheroid based cardiovascular regeneration using robotics engineering. 2013/03
• Osteochondral regeneration with scaffold free 3D-structure of swine adipose tissue-derived mesenchymal stem cells. 2013/03
• Cardiac or Vascular Tissue Spheroid 2013
• In Vitro Biofabrication of Tissues and Organs 2013
• Spheroids based scaffold-free tissue engineering for cardiovascular regeneration. 2012/10
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery. 2012/09
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery. 2012/09
• Building of HD MACs using cell processing robot for cartilage regeneration. 2012/04
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery. 2012/01
• Debubbling Device in Automated Cell Handling Robot 2012
• Development of scaffold-free bio rapid prototyping system 2011/10
• Development of scaffold-free bio rapid prototyping system. 2011/10
• Osteo-chondral regeneration by Adipose derived High Density Mesenchymal stem cell scaffold free Autologous Constructs 2011/09
• Fabrication of tissue engineered pulsatile 3-dimensional scaffold-free cardiac tissue from embryonic stem cells. 2011/04
• Osteo-Chondral regeneration by High Density Adipose Derived Mesenchymal stem cell scaffold free Autologous constructs 2011/03
• Cell Structure Production Device 2011
• Device for Manufacturing Supporting Body for Cell Structure 2011
• Transplant Guiding Part and Transplant Tool 2011
• Bio-rapd prototyping project: A simple method to build living 3 D micro patterned cell construct ex vivo without scaffold. 2010/10
• Osteo-chondral regeneration by High Density Mesenchymal stem cell scaffold free Autologous Constructs 2010/10
• Recent developments in mesenchymal stem cell growth and applications 2010/09
• Recent developments in mesenchymal stem cell growth and applications. 2010/09
• Bio-rapid prototyping project: A simple method to build living 3D micro patterned cell construct ex vivo without scaffold. 2010/01
• Establishment of an animal model of a pasteurized bone graft, with a preliminary analysis of muscle coverage or FGF-2 administration to the graft. 2009/08
• Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation. 2009/02
• Therapeutic Agent for Arthropathy for Intraarticular Administration 2009
• Method for Production of Three-Dimensional Structure of Cells 2009
• Overview of cartilage tissue engineering. 2007/09
• Depth Adjusting Drill 2007
• Device for Cell Transplantation 2006
• Contact stress at the post-cam mechanism in posterior-stabilised total knee arthroplasty. 2005/04
• Method of Constructing Artificial Joint 2005
• Plate for Recovering Biomaterial 2004

Books

• 人工血管－TEVGの臨床開発－;　2023
  ANNOUNCEMENT INFO.;　, 52, 3
  AUTHOR;　
  
• 3D Printing in Nephrology;　2022/10
  ANNOUNCEMENT INFO.;　Innovations in Nephrology, 141–156
  AUTHOR;　Nonaka T, Nagaishi Y, Murata D, Hara H, Nakayama K
  
• Involvement of the PI3K/AKT Pathway in the Formation and Fusion of Spheroids Derived from Human Dermal Fibroblast for Tissue Engineering Technology;　2022/08
  ANNOUNCEMENT INFO.;　Cell Tiss Biol, 16, 4, 312-329
  AUTHOR;　Amamoto S, Itoh M, Takahashi B, Kitsuka T, Uchihashi K, Muratad D, Node K, Nakayama K, Kamohara K
  
• Regeneration of Trachea and Esophagus by Scaffold-Free Structure, Using Bio-3D Printer;　2022/04
  ANNOUNCEMENT INFO.;　Nihon Kikan Shokudoka Gakkai Kaiho, Workshop3: Regenerative Medicine in Broncho-Esophagology, 73, 2, 179-180
  AUTHOR;　*R. Machino, K. Matsumoto, D. Taniguchi, F. Uchida, R. Hara, S. Oyama, M. Moriyama, T. Tsuchiya, T. Miyazaki, K. Tomoshige, R. Doi, S. Mizoguchi, T. Matsumoto, K. Nakayama, T. Nagayasu
  
• Kenzan Method for Scaffold-Free Biofabrication;　2021
  ANNOUNCEMENT INFO.;　Kenzan Method for Scaffold-Free Biofabrication, Editor:Koichi Nakayama
  AUTHOR;　Koichi Nakayama
  
• In Vitro Biofabrication of Tissues and Organs;　2013
  ANNOUNCEMENT INFO.;　Biofabrication: Micro-and Nano-fabrication. Printing Patterning and Assemblies, 1, 1-16
  AUTHOR;　Nakayama K
  

Original Articles

• Scaffold-free bone-like 3D structure established through osteogenic differentiation from human gingiva-derived stem cells;　2024/07
  ANNOUNCEMENT INFO.;　Biochemistry and Biophysics ReportsVolume, 38, July 2024
  AUTHOR;　Toyoda M, Fukuda T, Fujimoto R, Kawakami K, Hayashi C, Nakao Y, Watanabe Y, Aoki T,Shida M, Sanui T, Taguchi M, Yamamichi K, Okabe A, Okada T, Oka K, Nakayama K,Nishimura F, Kajioka S
  
• Creating 3D constructs with cranial neural crest-derived cell lines using a bio-3D printer;　2024/06
  ANNOUNCEMENT INFO.;　Journal of Oral Biosciences, 66(2): 339-348, June 2024
  AUTHOR;　Taguchi M, Yoshimoto S, Suyama K, Sumi S, Ohki S, Ogata K, Fujimoto R, Murata D, Nakayama K, Oka K
  
• Three-Dimensional Bio-Printed Tubular Tissue Using Dermal Fibroblast Cells as a New Tissue-Engineered Vascular Graft for Venous Replacement;　2024/05
  ANNOUNCEMENT INFO.;　ASAIO J. 2024 May 3
  AUTHOR;　Hayasaka, M, Kokudo T, Kaneko J, Chiyoda T, Nakamura A, Itoh M, Endo K, Nakayama K, Hasegawa K
  
• Special Issue: Biofabrication with Spheroid and Organoid Materials;　2023/07
  ANNOUNCEMENT INFO.;　Acta Biomater, 165, 1-3
  AUTHOR;　*Skylar-Scott M, Declercq H, Nakayama K
  
• Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique;　2023/07
  ANNOUNCEMENT INFO.;　Acta Biomater, 165, 102-110
  AUTHOR;　*Takagi K, Matsumoto K, Taniguchi D, Machino R, Uchida F, Hara R, Oishi K, Yamane Y, Iwatake M, Eguchi M, Mochizuki Y, Nakayama K, Nagayasu T
  
• Scaffold-free human vascular calcification model using a bio-three-dimensional printer;　2023/07
  ANNOUNCEMENT INFO.;　Biofabrication, 15, 4
  AUTHOR;　Nagaishi Y, Murata D, Yoshizato H, Nonaka T, Itoh M, Hara H, Nakayama K
  
• Special Issue: Biofabrication with Spheroid and Organoid Materials;　2023/07
  ANNOUNCEMENT INFO.;　, 165, 1-3
  AUTHOR;　Skylar-Scott M, Declercq H, Nakayama K
  
• Scaffold-free human vascular calcification model using a bio-three-dimensional printer;　2023/06
  ANNOUNCEMENT INFO.;　, 15, 4
  AUTHOR;　Nagaishi Y, Murata D, Yoshizato H, Nonaka T, Itoh M, Hara H, Nakayama K
  
• Enhanced chondrogenic differentiation of iPS cell-derived mesenchymal stem/stromal cells via neural crest cell induction for hyaline cartilage repair;　2023/05
  ANNOUNCEMENT INFO.;　Front Cell Dev Biol, 11, 1140717
  AUTHOR;　*Zujur D, Al-Akashi Z, Nakamura A, Zhao C, Takahashi K, Aritomi S, Theoputra W, Kamiya D, Nakayama K, Ikeya M
  
• Development of Beat Analysis Software for the Non-invasive Evaluation of Cardiac Constructs Fabricated with a Three-dimensional Bioprinter;　2023
  ANNOUNCEMENT INFO.;　Advanced Biomedical Engineering, 12, 138-146
  AUTHOR;　*Shimoto T, Arai K, Ichimura K, Nakayama K
  
• Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique ;　2022/10
  ANNOUNCEMENT INFO.;　Acta Biomater
  AUTHOR;　*Takagi K, Matsumoto K, Taniguchi D, Machino R, Uchida F, Hara R, Oishi K, Yamane Y, Iwatake M, Eguchi M, Mochizuki Y, Nakayama K, Nagayasu T
  
• Successful use of bio plugs for delayed bronchial closure after pneumonectomy in experimental settings;　2022/03
  ANNOUNCEMENT INFO.;　Interact Cardiovasc Thorac Surg, 34, 4, 660-667
  AUTHOR;　*Masaaki Moriyama, Keitaro Matsumoto, Daisuke Taniguchi, Ryusuke Machino, Tomoshi Tsuchiya, Koichi Nakayama, Takeshi Nagayasu
  
• Bio-3D printing of scaffold-free osteogenic and chondrogenic constructs using rat adipose-derived stromal cells ;　2022/02
  ANNOUNCEMENT INFO.;　Front Biosci (Landmark Ed), 27, 2, 52
  AUTHOR;　Ryota Fujimoto, Daiki Murata, Koichi Nakayama
  
• Osteochondral regeneration of the femoral medial condyle by using a scaffold-free 3D construct of synovial membrane-derived mesenchymal stem cells in horses ;　2022/01
  ANNOUNCEMENT INFO.;　BMC Vet Res, 18, 1, 53
  AUTHOR;　Daiki Murata, Shingo Ishikawa, Takafumi Sunaga, Yasuo Saito, Takeshi Sogawa, Koichi Nakayama, Seiji Hobo, Takashi Hatazoe
  
• Scaffold-Free Tubular Engineered Heart Tissue From Human Induced Pluripotent Stem Cells Using Bio-3D Printing Technology in vivo;　2022/01
  ANNOUNCEMENT INFO.;　Front Cardiovasc Med, 8, 806215
  AUTHOR;　*Yujiro Kawai, Shugo Tohyama, Kenichi Arai, Tadashi Tamura, Yusuke Soma, Keiichi Fukuda, Hideyuki Shimizu, Koichi Nakayama, Eiji Kobayashi
  
• Establishment of large canine hepatocyte spheroids by mixing vascular endothelial cells and canine adipose-derived mesenchymal stem cells;　2021/12
  ANNOUNCEMENT INFO.;　Regen Ther, 19, 1-8
  AUTHOR;　*Akito Ichikawa, Sakurako Neo, Ryouhei Nukui, Yoko Yamada, Suguru Nitta, Hidetoshi Iwaki, Yusuke Yanagi, Koichi Nakayama, Shoichi Sato, Satoko Tateishi, Masaharu Hisasue
  
• Bio-3D printing iPSCs-derived human chondrocytes for articular cartilage regeneration;　2021/08
  ANNOUNCEMENT INFO.;　Biofabrication, 13, 4
  AUTHOR;　Nakamura A, Murata D, Fujimoto R, Tamaki S, Nagata S, Ikeya M, Toguchida J, Nakayama K
  
• Mechanism of Peripheral Nerve Regeneration Using a Bio 3D Conduit Derived from Normal Human Dermal Fibroblasts ;　2021/05
  ANNOUNCEMENT INFO.;　J Reconstr Microsurg, 37, 4, 357-364
  AUTHOR;　*Hirofumi Yurie, Ryosuke Ikeguchi, Tomoki Aoyama, Akira Ito, Mai Tanaka, Takashi Noguchi, Hiroki Oda, Hisataka Takeuchi, Sadaki Mitsuzawa, Maki Ando, Koichi Yoshimoto, Shizuka Akieda, Koichi Nakayama, Shuichi Matsuda
  
• Bile duct reconstruction using scaffold-free tubular constructs created by Bio-3D printer ;　2021/02
  ANNOUNCEMENT INFO.;　Regen Ther, 16, 81-89
  AUTHOR;　*Takashi Hamada, Anna Nakamura, Akihiko Soyama, Yusuke Sakai, Takayuki Miyoshi, Shun Yamaguchi, Masaaki Hidaka, Takanobu Hara, Tota Kugiyama, Mitsuhisa Takatsuki, Akihide Kamiya, Koichi Nakayama, Susumu Eguchi
  
• Regular Papers Study on Pipetting Motion Optimization of Automatic Spheroid Culture System for Spheroid Formation;　2021/02
  ANNOUNCEMENT INFO.;　J Robot Mechatron, 33, 1, 78-87
  AUTHOR;　*Shimoto T, Teshima C, Watanabe T, Xiu-Ying Zhang, Ishikawa A, Higaki H, Nakayama K
  
• Long-Term Outcome of Sciatic Nerve Regeneration Using Bio3D Conduit Fabricated from Human Fibroblasts in a Rat Sciatic Nerve Model ;　2021
  ANNOUNCEMENT INFO.;　Cell Transplant, 30, 9636897211021357
  AUTHOR;　*Maki Ando, Ryosuke Ikeguchi, Tomoki Aoyama, Mai Tanaka, Takashi Noguchi, Yudai Miyazaki, Shizuka Akieda, Koichi Nakayama, Shuichi Matsuda
  
• Fabrication of Cardiac Constructs Using Bio-3D Printer ;　2021
  ANNOUNCEMENT INFO.;　Methods Mol Biol, 2320, 53-63
  AUTHOR;　*Kenichi Arai, Daiki Murata, Shoko Takao, Koichi Nakayama
  
• Correction: Cryopreservation method for spheroids and fabrication of scaffold-free tubular constructs ;　2020/11
  ANNOUNCEMENT INFO.;　PLoS One , 15, 11, e0243249
  AUTHOR;　*Kenichi Arai, Daiki Murata, Shoko Takao, Ana Raquel Verissiomo, Koichi Nakayama
  
• Correction: Fabrication of scaffold-free tubular cardiac constructs using a Bio-3D printer;　2020/11
  ANNOUNCEMENT INFO.;　PLoS One, 15, 11, e0243244
  AUTHOR;　*Kenichi Arai, Daiki Murata, Ana Raquel Verissimo, Yosuke Mukae, Manabu Itoh, Anna Nakamura, Shigeki Morita, Koichi Nakayama
  
• Mechanism of Peripheral Nerve Regeneration Using a Bio 3D Conduit Derived from Normal Human Dermal Fibroblasts;　2020/09
  ANNOUNCEMENT INFO.;　J Reconstr Microsurg
  AUTHOR;　*Hirofumi Yurie, Ryosuke Ikeguchi, Tomoki Aoyama, Akira Ito, Mai Tanaka, Takashi Noguchi, Hiroki Oda, Hisataka Takeuchi, Sadaki Mitsuzawa, Maki Ando, Koichi Yoshimoto, Shizuka Akieda, Koichi Nakayama, Shuichi Matsuda
  
• Scaffold-Free Bio-3D Printing Using Spheroids as "Bio-Inks" for Tissue (Re-)Construction and Drug Response Tests.;　2020/08
  ANNOUNCEMENT INFO.;　Adv Healthc Mater, 9, 15, e1901831
  AUTHOR;　Murata D, Arai K, Nakayama K
  
• Osteochondral regeneration using scaffold-free constructs of adipose tissue-derived mesenchymal stem cells made by a bio three-dimensional printer with a needle-array in rabbits;　2020/07
  ANNOUNCEMENT INFO.;　Regen Ther, 15, 77-89
  AUTHOR;　Murata D, Kunitomi Y, Harada K, Tokunaga S, Takao S, Nakayama K
  
• Pro-angiogenic scaffold-free Bio three-dimensional conduit developed from human induced pluripotent stem cell–derived mesenchymal stem cells promotes peripheral nerve regeneration;　2020/07
  ANNOUNCEMENT INFO.;　Sci Rep, 10, 1, 12034
  AUTHOR;　*Mitsuzawa S, Zhao C, Ikeguchi R, Aoyama T, Kamiya D, Ando M, Takeuchi H, Akieda S, Nakayama K, Matsuda S, Ikeya M
  
• Drug Response Analysis for Scaffold-Free Cardiac Constructs Fabricated Using bio-3D Printer;　2020/06
  ANNOUNCEMENT INFO.;　Sci Rep, 10, 1, 8972
  AUTHOR;　*Arai K, Murata D, Takao S, Nakamura A, Itoh M, Kitsuka T, Nakayama K
  
• Osteochondral Regeneration Using Adipose TissueDerived Mesenchymal Stem Cells;　2020/05
  ANNOUNCEMENT INFO.;　Int J Mol Sci ., 21, 10, E3589
  AUTHOR;　Murata D, Fujimoto R, Nakayama K
  
• Human lung microvascular endothelial cells as potential alternatives to human umbilical vein endothelial cells in bio-3D-printed trachea-like structures.;　2020/04
  ANNOUNCEMENT INFO.;　Tissue Cell., 63, 101321
  AUTHOR;　*Taniguchi D, Matsumoto K, Machino R, Takeoka Y, Elgalad A, Taura Y, Oyama S, Tetsuo T, Moriyama M, Takagi K, Kunizaki M, Tsuchiya T, Miyazaki T, Hatachi G, Matsuo N, Nakayama K, Nagayasu T
  
• Cryopreservation method for spheroids and fabrication of scaffold-free tubular constructs.　;　2020/04
  ANNOUNCEMENT INFO.;　PLoS One., 15, 4, e0230428
  AUTHOR;　*Arai K, Murata D, Takao S, Verissiomo AR, Nakayama K
  
• A scaffold-free Bio 3D nerve conduit for repair of a 10-mm peripheral nerve defect in the rats;　2020/02
  ANNOUNCEMENT INFO.;　Microsurgery., 40, 2, 207-216
  AUTHOR;　*Takeuchi H, Ikeguchi R, Aoyama T, Oda H, Yurie H, Mitsuzawa S, Tanaka M, Ohta S, Akieda S, Miyazaki Y, Nakayama K, Matsuda S
  
• Bio 3D Conduits Derived from Bone Marrow Stromal Cells Promote Peripheral Nerve Regeneration;　2020
  ANNOUNCEMENT INFO.;　Cell Transplant, 29, 963689720951551
  AUTHOR;　*Hirofumi Yurie, Ryosuke Ikeguchi, Tomoki Aoyama, Mai Tanaka, Hiroki Oda, Hisataka Takeuchi, Sadaki Mitsuzawa, Maki Ando, Koichi Yoshimoto, Takashi Noguchi, Shizuka Akieda, Koichi Nakayama, Shuichi Matsuda
  
• 2-Cl-C.OXT-A stimulates contraction through the suppression of phosphodiesterase activity in human induced pluripotent stem cell-derived cardiac organoids.;　2019/07
  ANNOUNCEMENT INFO.;　PLoS One., 14, 7, e0213114
  AUTHOR;　〇Kitsuka T, Itoh M, Amamoto S, Arai K, Oyama J, Node K, Toda S, Morita S, Nishida T, Nakayama K.
  
• Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes.;　2019/05
  ANNOUNCEMENT INFO.;　Nat Commun., 10, 1, 2244
  AUTHOR;　〇Itoh M, Mukae Y, Kitsuka T, Arai K, Nakamura A, Uchihashi K, Toda S, Matsubayashi K, Oyama J, Node K, Kami K, Gojo S, Morita S, Nishida T, Nakayama K, Kobayashi E.
  
• Histological evaluation of tendon formation using a scaffold-free three-dimensional-bioprinted construct of human dermal fibroblasts under in vitro static tensile culture ;　2019/05
  ANNOUNCEMENT INFO.;　Regenerative Therapy, 11, 47–55
  AUTHOR;　*Nakanishi Y, Okada T, Takeuchi N,Kozono N, Senjyu T, Nakayama K, Nakashima Y
  
• Correction: Regeneration of esophagus using a scaffold-free biomimetic structure created with bio-three-dimensional printing;　2019/04
  ANNOUNCEMENT INFO.;　PLoS One, 14, 4, e0216174
  AUTHOR;　*Yosuke Takeoka, Keitaro Matsumoto, Daisuke Taniguchi, Tomoshi Tsuchiya, Ryusuke Machino, Masaaki Moriyama, Shosaburo Oyama, Tomoyuki Tetsuo, Yasuaki Taura, Katsunori Takagi, Takuya Yoshida, Abdelmotagaly Elgalad, Naoto Matsuo, Masaki Kunizaki, Shuichi Tobinaga, Takashi Nonaka, Shigekazu Hidaka, Naoya Yamasaki, Koichi Nakayama, Takeshi Nagayasu
  
• Replacement of Rat Tracheas by Layered, Trachea-like, Scaffold-free Structures of Human Cells Using Bio-3D Printing System.;　2019/04
  ANNOUNCEMENT INFO.;　Adv Healthc Mater. , 8, 7, e1800983
  AUTHOR;　*Machino R, Matsumoto K, Taniguchi D, Tsuchiya T, Takeoka Y, Taura Y, Moriyama M, Tetsuo T, Oyama S, Takagi K, Miyazaki T, Hatachi G, Doi R, Shimoyama K, Matsuo N, Yamasaki N, Nakayama K, Nagayasu T
  
• Regeneration of esophagus using a scaffold-free biomimetic structure created with bio-three-dimensional printing;　2019/03
  ANNOUNCEMENT INFO.;　PLoS One. , 14, 3, e0211339
  AUTHOR;　*Takeoka Y, Matsumoto K, Taniguchi D, Tsuchiya T, Machino R, Moriyama M, Oyama S, Tetsuo T, Taura Y, Takagi K, Yoshida T, Abdelmotagaly Elgalad, Matuo N, Kunizaki M, Tobinaga S, Nonaka T, Hidaka S, Yamasaki N, Nakayama K, Nagayasu T
  
• A Scaffold-Free Allogeneic Construct From Adipose-Derived Stem Cells　Regenerates an Osteochondral Defect in a Rabbit Model;　2019/02
  ANNOUNCEMENT INFO.;　Arthroscopy. , 35, 2, 583-593
  AUTHOR;　*Oshima T, Nakase J, Toratani T, Numata H, Takata Y, Nakayama K, Tsuchiya H.
  
• The Efficacy of a Scaffold-free Bio 3D Conduit Developed from Autologous Dermal Fibroblasts on Peripheral Nerve Regeneration in a Canine Ulnar Nerve Injury Model: A Preclinical Proof-of-Concept Study.;　2019
  ANNOUNCEMENT INFO.;　Cell Transplant.
  AUTHOR;　*Mitsuzawa S, Ikeguchi R, Aoyama T, Takeuchi H, Yurie H, Oda H, Ohta S, Ushimaru M, Ito T, 　Tanaka M, Kunitomi Y, Tsuji M, Akieda S, Nakayama K, Matsuda S.
  
• Regeneration of diaphragm with bio-3D cellular patch;　2018/06
  ANNOUNCEMENT INFO.;　Biomaterials, 167, 1-14
  AUTHOR;　Xiu-Ying Zhang,Yanagi Y,Zijing Sheng,Nagata K,Nakayama K,Taguchi T.
  
• Scaffold-free trachea regeneration by tissue engineering with bio-three- dimensional printing;　2018/04
  ANNOUNCEMENT INFO.;　Interact Cardiovasc Thorac Surg., 26, 5, 745-752
  AUTHOR;　Taniguchi D, Matsumoto K, Tsuchiya T, Machino R, Takeoka Y, Elgalad A, Gunge K, Takagi K, Taura Y, Hatachi G, Matsuo N, Yamasaki N, Nakayama K, Nagayasu T.
  
• Fabrication of scaffold-free tubular cardiac constructs using a bio-3D printer.;　2018
  ANNOUNCEMENT INFO.;　PLoS One., 13, 12, e0209162
  AUTHOR;　Arai K, Murata D, Verissimo AR, Mukae Y, Itoh M, Nakamura A, Morita S, Nakayama K (8)
  
• The addition of human iPS cell-derived neural progenitors changes the contraction of human iPS cell-derived cardiac spheroids　;　2018
  ANNOUNCEMENT INFO.;　Tissue and Cell, 53, 61-67
  AUTHOR;　Mukae Y，Itoh M，Noguchi R，Furukawa K，Arai K，Oyama J，Toda S，Nakayama K，Node K，Morita S
  
• Osteochondral regeneration with a scaffold-free three-dimensional construct of adipose tissue-derived mesenchymal stromal cells in pigs.;　2018
  ANNOUNCEMENT INFO.;　Tissue Engineering and Regenerative Medicine, 15, 1, 101-113
  AUTHOR;　Murata D, Akieda S, Misumi K, Nakayama K.
  
• In vivo and ex vivo methods of growing a liver bud through tissue connection;　2017/10
  ANNOUNCEMENT INFO.;　Sci Rep., 7, 1, 14085
  AUTHOR;　Yanagi Y, Nakayama K, Taguchi T, Enosawa S, Tamura T, Yoshimaru K, Matsuura T, Hayashida M, Kohashi K, Oda Y, Yamaza T, Kobayashi E.
  
• Principles of the ‘Kenzan’ method for robotic cell spheroid-based three-dimensional bioprinting.;　2017/06
  ANNOUNCEMENT INFO.;　Tissue Engineering Part B:Reviews, 23, 3, 237-244
  AUTHOR;　Moldovan NI, Hibino N, Nakayama K
  
• The efficacy of a scaffold-free bio 3D conduit developed from human fibroblasts on peripheral nerve regeneration in a rat sciatic nerve model.;　2017/02
  ANNOUNCEMENT INFO.;　PLoS One, 12, 2, e0171448
  AUTHOR;　Yurie H, Ikeguchi R, Aoyama T, Kaizawa Y, Tajino J, Ito A, Ohta S, Oda H, Takeuchi H, Akieda S, Tsuji M, Nakayama K, Matsuda S.
  
• Scaffold-free tissue-engineered allogenic adipose-derived stem cells promote meniscus healing.;　2017/02
  ANNOUNCEMENT INFO.;　Arthroscopy: The Journal of Arthroscopic and Related Surgery, 33, 2, 346-354
  AUTHOR;　Toratani T, Nakase J, Numata H, Oshima T, Takata Y, Tsuchiya H,Nakayama K.
  
• Development of a three-dimensional pre-vascularized scaffold-free contractile cardiac patch for treating heart disease.;　2016/01
  ANNOUNCEMENT INFO.;　The Journal of Heart and Lung Transplantation, 35, 1, 137-145
  AUTHOR;　Noguchi R, Nakayama K, Itoh M, Kamohara K, Furukawa K, Oyama J, Node K, Morita S.
  
• MP19-17 Human urethra-engineered with human mesenchymal stem cell with maturation by rearrangement of cells for self-organization -newly developed scaffold-free three-dimensional bio-printer.;　2015/04
  ANNOUNCEMENT INFO.;　The Journal of Urology April 2015, 193, 4 Supplement, e221-e222
  AUTHOR;　Yamamoto T, Funahashi Y, Mastukawa Y, Tsuji Y, Mizuno H, Nakayama K, Gotoh M.
  
• A preliminary study of osteochondral regeneration using a scaffold-free three-dimensional construct of porcine adipose tissue-derived mesenchymal stem cells.;　2015/03
  ANNOUNCEMENT INFO.;　Journal of Orthopaedic Surgery and Research 2015 March, 10, 35
  AUTHOR;　Murata D, Tokunaga S, Tamura T, Kawaguchi H, Miyoshi N, Fujiki M, Nakayama K, Misumi K
  
• Correction: Scaffold-Free Tubular Tissues Created by a Bio-3D Printer Undergo Remodeling and Endothelialization when Implanted in Rat Aortae.;　2015
  ANNOUNCEMENT INFO.;　PLoS One., 10, 12, e0145971
  AUTHOR;　Itoh M, Nakayama K, Noguchi R, Kamohara K, Furukawa K, Uchihashi K, Toda S, Oyama J, Node K, Morita S.
  
• Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells.;　2014/10
  ANNOUNCEMENT INFO.;　Journal of Orthopaedic Surgery and Research 2014 October, 14, 9, 98
  AUTHOR;　Ishihara K, Nakayama K, Akieda S, Matsuda S, Iwamoto Y.
  
• Multipotency of equine mesenchymal stem cells derived from synovial fluid.;　2014/10
  ANNOUNCEMENT INFO.;　The Veterinary Journal 2014 October, 202, 1, 53-61
  AUTHOR;　Murata D, Miyakoshi D, Hatazoe T, Miura N, Tokunaga S, Fujiki M, Nakayama K, Misumi K
  
• Bio rapid prototyping project: Development of spheroid formation system for regenerative medicine.;　2013/07
  ANNOUNCEMENT INFO.;　Information Technology Convergence, Lecture Notes in Electrical Engineering, 253, 855-862
  AUTHOR;　Shimoto T, Hidaka N, Sasaki H, Nakayama K, Akieda S, Matsuda S, Miura H, Iwamoto Y.
  
• Development of 3-dimensional prevascularized scaffold-free contractile cardiac patch for heart regeneration.;　2013/04
  ANNOUNCEMENT INFO.;　The Journal of Heart and Lung Transplantation April 2013, 32, 4 Supplement, S46
  AUTHOR;　Noguchi R, Nakayama K, Itoh M, Kamohara K, Furukawa K, Oyama J, Node K, Morita S
  
• Building of HD MACs using cell processing robot for cartilage regeneration.;　2012/04
  ANNOUNCEMENT INFO.;　Journal of Robotics and Mechatronics., 24, 2, 347-353
  AUTHOR;　Shimoto T, Nakayama K, Matsuda S, Iwamoto Y
  
• Establishment of an animal model of a pasteurized bone graft, with a preliminary analysis of muscle coverage or FGF-2 administration to the graft.;　2009/08
  ANNOUNCEMENT INFO.;　Journal of Orthopaedic Surgery and Research 2009 Aug, 4, 31
  AUTHOR;　Yoshida T, Sakamoto A, Tsukamoto N, Nakayama K, Iwamoto Y
  
• Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation.;　2009/02
  ANNOUNCEMENT INFO.;　Osteoarthritis Cartilage 2009 Feb., 17, 2, 235-243
  AUTHOR;　Akasaki Y, Matsuda S, Nakayama K, Fukagawa S, Miura H, Iwamoto Y.
  
• Contact stress at the post-cam mechanism in posterior-stabilised total knee arthroplasty.;　2005/04
  ANNOUNCEMENT INFO.;　Journal of Bone and Joint Surgery British Volume 2005 April, 87-B, 4, 483-488
  AUTHOR;　Nakayama K, Matsuda S, Miura H, Iwamoto Y, Higaki H, Otsuka K
  

Material, Commentary, Editorials, Research Report, A Comprehensive Journal Articles

• Construction of scaffold-free three dimensional liver tissue by spheroid fusion using the bio 3D printer.;　2013/09
  ANNOUNCEMENT INFO.;　The 24th Fukuoka International Symposium on Pediatric/Maternal-Child Health research. (Sept., 2013 Fukuoka)
  AUTHOR;　Yanagi Y, Hayashida M, Yoshimaru K, Nakayama K, Taguchi T.
  

General Lectures

• Xenograft of bio-3D printed scaffold-free cartilage constructs for regeenration of articular cartilage in immunodeficient pigs;　2024/06
  ANNOUNCEMENT INFO.;　7th Tissue Engineering and Regenerative Medicine International Society World Congress(Jun.25-28,2024 USA)
  AUTHOR;　Nonaka T, Murata D, Nakamura A, Yoshizato H, Kashimoto S, Itoh M, Ikeya M, Toguchida J, Mawatari M, Nakayama K
  
• Scaffold-free constructs comprising adipose tissue-derived mesenchymal stem cells produced by a bio-3D printer promote bone-tendon healing after anterior cruciate ligament reconstruction in rabbit models.;　2024/06
  ANNOUNCEMENT INFO.;　7th Tissue Engineering and Regenerative Medicine International Society World Congress(Jun.25-28,2024 USA)
  AUTHOR;　Higa K, Yabiku H, Uehara F, Toma T, Azuma C, Murata D, Nakayama K, Nishida K
  
• Regeneration of the patellar tendon using scaffold-free 3D constructs consisted of adipose tissue-derived mesenchymal stem cells in rabbits;　2024/06
  ANNOUNCEMENT INFO.;　7th Tissue Engineering and Regenerative Medicine International Society World Congress(Jun.25-28,2024 USA)
  AUTHOR;　Kashimoto S, Murata D, Yoshizato H, Nonaka T, Nakamura A, Mawatari M, Nakayama K
  
• Scaffold-free cartilage constructs for large chondral defects fabricated using bio-3D printer;　2023/11
  ANNOUNCEMENT INFO.;　14th ACTO Annual Meeting, 2023,11,6-8
  AUTHOR;　Nakamura A, Nonaka T, Murata D, Ikeya M, Toguchida J, Nakayama K
  
• Scaffold-free 3D osteogenic construct composed of human bone marrow-derived mesenchymal stem cells and human umbilical vein endothelial cells;　2023/11
  ANNOUNCEMENT INFO.;　14th ACTO Annual Meeting, 2023,11,6-8
  AUTHOR;　Yoshizato H, Murata D, Nonaka T, Nakayama K, Mawatari M
  
• The early effects of scaffold-free constructs of adipose tissue-derived mesenchymal stem cells on tendon-bone healing after anterior cruciate ligament reconstruction in a rabbit model;　2021
  ANNOUNCEMENT INFO.;　2021 6th TERMIS World Congress, 2021,11,15-19
  AUTHOR;　*Higa K, Matsuda H, Uehara F, Toma T, Azuma C, Murata D, Nakayama K, Nishida K
  
• Tendon/ligament regeneration using a scaffold-free biofabricated 3D construct of Autologous adipose tissue-derived mesenchymal stem cells in rabbits;　2021
  ANNOUNCEMENT INFO.;　2021 6th TERMIS World Congress, 2021,11,15-19
  AUTHOR;　Murata D, Fujimoto R, Takao S, Miyake M, Nakamura A, Nakayama K
  
• Ligament reconstruction using Scaffold-free Cell Construct produced by Bio Three-dimensional Printer.;　2019/10
  ANNOUNCEMENT INFO.;　BioFabrication2019, 2019.10.20-22
  AUTHOR;　Murata D, Miyake M, Takao S, Nakamura A, Arai K, Nakayama K.
  
• Drug response of scaffold-free cardiac constructs fabricated using bio-3D printing;　2019/10
  ANNOUNCEMENT INFO.;　BioFabrication2019, 2019.10.20-22
  AUTHOR;　Arai K, Murata D, Nakayama K.
  
• Scaffold-free ligament structures produced by using bio three-dimensional printer;　2018/10
  ANNOUNCEMENT INFO.;　International Conference on Biofabrication 2018, 2018.10.28-31
  AUTHOR;　Murata D, Nakamura A, Takao S, Arai K, Nakayama K
  
• Toward in vitro construction of iPSC-derived human heart-like tissus;　2018/09
  ANNOUNCEMENT INFO.;　5th TERMIS World Congress - 2018 Kyoto, JAPAN, 2018.9.4-7
  AUTHOR;　Julia Junghof，Nakayama K，Yoshida Y　
  
• Drug response of scaffold-free cardiac constructs fabricated using bio-3D printing;　2018/09
  ANNOUNCEMENT INFO.;　5th TERMIS World Congress - 2018 Kyoto, JAPAN, 2018.9.4-7
  AUTHOR;　Arai K,VerissimoA.R,Nakayama K
  
• Ligament structures produced by using bio three-dimensional printer;　2018/09
  ANNOUNCEMENT INFO.;　5th TERMIS World Congress - 2018 Kyoto, JAPAN, 2018.9.4-7
  AUTHOR;　Murata D,Nakamura A,Arai K,Nakayama K
  
• Artificial trachea and esophagus using bio 3D printer;　2018/09
  ANNOUNCEMENT INFO.;　5th TERMIS World Congress - 2018 Kyoto, JAPAN, 2018.9.4-7
  AUTHOR;　Matsumoto K，Taniguchi D，Takeoka Y，Machino R，Taura Y，Takagi K，Oyama S，Tetsuo T，Moriyama M，Matsuo N，Kunizaki M，Hidaka S，Tsuchiya T，Nakayama K
  
• The efficacy of a Scaffold-free Bio 3D conduit developed from dermal fibroblasts on periheral nerve regeneration in a canine ulnar injury model;　2018/09
  ANNOUNCEMENT INFO.;　5th TERMIS World Congress - 2018 Kyoto, JAPAN, 2018.9.4-7
  AUTHOR;　Mituzawa S，Ikeguchi R，Aoyama T，Takeuchi H，Yurie H，Oda H，Ohta S，Tsuji M，Akieda S，Nakayama K，Matsuda S
  
• The KenZan method：from bench to bedside;　2018/09
  ANNOUNCEMENT INFO.;　5th TERMIS World Congress - 2018 Kyoto, JAPAN, 2018.9.4-7
  AUTHOR;　Nakayama K
  
• Osteochondral Regeneration Using A Scaffold-Free 3D-Construct of SM -Mscs In Horse;　2018/04
  ANNOUNCEMENT INFO.;　ICRS(International Cartilage Repair Society) 2018-14th World Congress Macau (April 09-12, 2018, China)　
  AUTHOR;　Murata D, Ishikawa S, Saito Y, Sunaga T, Sagawa T, Fujiki M, Misumi K, Nakayama K, Hobo S, Hatazoe T.
  
• Scaffold-free Bio-3D Printing for Solid organ fabrication;　2017/10
  ANNOUNCEMENT INFO.;　ACTO 2017-The 8th meeting of Asian Cellular Therapy Organization, 2017, 10, 27-29
  AUTHOR;　Nakayama K
  
• Regenerative Medicine;　2017/10
  ANNOUNCEMENT INFO.;　ACTO(Asian Cellular Therapy Organization Secretariat)2017 (Oct.27-29 2017,Japan)
  AUTHOR;　Sawa Y,Kojima H,Nakayama K,Jay L,Michael M.
  
• 3D bioprinted scaffold-free blood vessels for clinical and research applications;　2017/06
  ANNOUNCEMENT INFO.;　TERMIS European Chapter Meeting 2017 (Jun.26-30,2017,Switzerland)
  AUTHOR;　VerissimoA.R,Nakamura A,Matsubayashi K,Mukae Y,Itoh M,Nakayama K.
  
• Osteochondral regeneration using a scaffold-free construct of adipose tissue-derived mesenchymal stem cells made by bio three-dimensional printer with needle-array in pigs;　2017
  ANNOUNCEMENT INFO.;　ICRS Heritage Summit Gothenburg 2017, 2017, 6, 29 - 7, 1
  AUTHOR;　Murata D, Kunitomi Y, Harada K, Song D, Sunaga T, Nakayama K, Sogawa T, Fujiki M, Misumi K
  
• Bio 3D printing scaffold-free blood vessels.;　2016/12
  ANNOUNCEMENT INFO.;　2016 Joint Annual Scientific Meeting of The Australian Atherosclerosis Society, (AAS), High Blood Pressure Research Council of Australia, (HBPRCA), and Australian Vascular Biology Society, (AVBS) (Dec.7-11, 2016,Australia)
  AUTHOR;　Verissimo A.R, Nakamura A, Matsubayashi K, Itoh M, Nakayama K.
  
• Scaffold-free bio-3D printing for solid organ fabrication.;　2016/11
  ANNOUNCEMENT INFO.;　The 7th meeting of Asian Cellular Therapy Organization(ACTO)(Nov.11-13,2016,China)
  AUTHOR;　Nakayama K.
  
• Scaffold-free bio-3D printing for solid organ fabrication.;　2016/11
  ANNOUNCEMENT INFO.;　2016 The 7th Annual Meeting of Asian Cellular Therapy Organization (Nov. 11-13, 2016 China)
  AUTHOR;　Nakayama K.
  
• Fabrication of scaffold-free cardiac construct by bio ３D-printer.;　2016/10
  ANNOUNCEMENT INFO.;　International Conference on Biofabrication (Oct. 29-31, 2016 U.S.A)
  AUTHOR;　Arai K, Ojima A, Mukae Y, Morita S, Nakayama K.
  
• Addition of human iPS-derived neural progenitors influences the contractile function of cardiac spheroids.;　2016/10
  ANNOUNCEMENT INFO.;　International Conference on Biofabrication (Oct. 29-31, 2016 U.S.A.) Poster
  AUTHOR;　Mukae Y, Itoh M, Furukawa K, Kitsuka T, Arai K, Oyama J, Nakayama K, Node K, Morita S.
  
• Bio 3D printed solid cartilage from iPSC-derived chondrocyte.;　2016/09
  ANNOUNCEMENT INFO.;　ICRS 2016 - 13th World Congress (Sep. 24-27, 2016 Italy)
  AUTHOR;　Komoda H, Tanaka M, Nagaike M, Nagata S, Toguchida J, Nakayama K.
  
• Osteochondral regeneration of the loading-bearing site using a scaffold-free 3D construct of swine AT-MSCs.;　2016/09
  ANNOUNCEMENT INFO.;　ICRS 2016 - 13th World Congress (Sep.24-27, 2016 Italy)
  AUTHOR;　Murata D, Tokunaga S, Akieda S, Nakayama K, Setoyama K, Fujiki M, Misumi K.
  
• Osteochondral regeneration by implanting a scaffold-free construct of swine AT-MSCs using a bio 3D printer.;　2016/09
  ANNOUNCEMENT INFO.;　ICRS 2016 - 13th World Congress (Sep. 24-27, 2016 Italy) 　
  AUTHOR;　Yamasaki A, Matsuzaki S, Murata D, Sunaga T, Tantan S, Kunitomi Y, Harada K, Nakayama K, Misumi K.
  
• Scaffold-free Bio-3D printing for solid organ fabrication.;　2016/06
  ANNOUNCEMENT INFO.;　European Chapter Meeting of the Tissue Engineering and Regenerative International Society 2016(TERMIS) (June 28-July 1, 2016 Sweden)
  AUTHOR;　Nakayama K.
  
• Scaffold-free 3D tissue & organ fabrication by bio-3D printer.;　2016/03
  ANNOUNCEMENT INFO.;　The 19th US-Japan Cellular and Gene Therapy Conference. 3D Modeling and Printing of Tissues and Organs. (Mar.9, 2016,U.S.A.)
  AUTHOR;　Nakayama K.
  
• A new strategy for liver tissue fabrication and transplantation.;　2016/02
  ANNOUNCEMENT INFO.;　The 25th conference of APASL(Asian Pacific Association for the study of the liver)(Feb.20-24,2016 Tokyo)
  AUTHOR;　Yanagi Y, Kobayashi E, Nakayama K, Enosawa S, Kohashi K, Yoshimaru K, Matsuura T, Yamaza T, Taguchi T.
  
• The fabrication of scaffold free cardiomyocytes constructs by using Bio-3D printer.;　2015/11
  ANNOUNCEMENT INFO.;　Biofabrication 2015 (Nov. 7-11, 2015 Utrecht, Netherlands)
  AUTHOR;　Arai K, Ojima A, Matsubayashi K, Nakayama K
  
• The effectiveness of using a bio-3D printer in the development of a scaffold-free regenerative vascular graft.;　2015/09
  ANNOUNCEMENT INFO.;　2015 4th TERMIS World Congress (Sept. 8 - 11, 2015 Boston, U.S.A.) Poster
  AUTHOR;　Itoh M, Mukae Y, Matsubayashi K, Kawakatsu M, Furukawa K, Uchihashi K, Toda S, Oyama J, Node K, Nakayama K, Morita S.
  
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery.;　2015/09
  ANNOUNCEMENT INFO.;　2015 4th TERMIS World Congress (Sept. 8 - 11, 2015 Boston, U.S.A.) Poster
  AUTHOR;　Nakayama K.
  
• Osteochondral regeneration using a scaffold free three-dimensional construct of swine adipose tissue-derived mesenchymal stem cells.;　2015/09
  ANNOUNCEMENT INFO.;　2015 4th TERMIS World Congress (Sept. 8 - 11, 2015 Boston, U.S.A.)
  AUTHOR;　Murata D, Tokunaga S, Akieda S, Fujiki M, Nakayama K, Misumi K.
  
• Implantation of scaffold-free tubular tissue using a bio-3D printer augments vascular remodeling and endothelialization.;　2014/11
  ANNOUNCEMENT INFO.;　American Heart Association SCIENTIFIC SESSIONS 2014 (Nov. 15-19, 2014)
  AUTHOR;　Itoh M, Nakayama K, Noguchi R, Kamohara K, Furukawa K, Uchihashi K, Toda S, Oyama J. Node K, Morita S.
  
• A new approach for 3D tissue & organ fabricatoin inspired from orthopedic surgery.;　2014/11
  ANNOUNCEMENT INFO.;　The 1st International Conference & Exhibition for Nanopia (Nov. 13-14, 2014 Korea)
  AUTHOR;　Nakayama K
  
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery.;　2014/11
  ANNOUNCEMENT INFO.;　The 5th meeting of Asian Cellular Therapy Organization (Nov. 10-12, 2014 Osaka)
  AUTHOR;　Nakayama K
  
• In vitro fabrication of scaffold-free meniscus-like constructs using bio-3D Printer.;　2014/07
  ANNOUNCEMENT INFO.;　ICJR Pan Pacific Orthopaedic Congress (July 16-18, 2014 Hawaii, U.S.A.)
  AUTHOR;　Oshima T, Iwasaki R, Kawakatsu M, Tanaka M, Nakayama K
  
• Three dimensional construct fabrication and mechanical pressure culture enhance.;　2014/07
  ANNOUNCEMENT INFO.;　ICJR Pan Pacific Orthopaedic Congress (July 16-18, 2014 Hawaii, U.S.A.)
  AUTHOR;　Iwasaki R, Oshima T, Kawakatsu M, Tanaka M, Nakayama K
  
• Construction of scaffold-free three dimensional liver tissue by spheroid fusion using the bio 3D printer.;　2013/09
  ANNOUNCEMENT INFO.;　The 24th Fukuoka International Symposium on Pediatric/Maternal-Child Health research. (Sep.2013,Japan)
  AUTHOR;　Nakayama K.
  
• Osteochondral regeneration with scaffold free 3D-structure of swine adipose tissue-derived mesenchymal stem cells.;　2013/09
  ANNOUNCEMENT INFO.;　ICRS2013 (Sep, 2013 Izmir, Turkey) Poster
  AUTHOR;　Murata D, Tokunaga S, Tamura T, Kawaguchi H, Fujiki M, Miyoshi N, Nakayama K, Misumi K.
  
• Development of 3-dimensional prevascularized scaffold-free contractile cardiac patch for heart regeneration.;　2013/04
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Noguchi R, Nakayama K, Itoh M, Kamohara K, Furukawa K, Oyama J, Node K, Morita S
  
• Spheroid based cardiovascular regeneration using robotics engineering.;　2013/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Noguchi R, Nakayama K, Node K, Morita S
  
• Osteochondral regeneration with scaffold free 3D-structure of swine adipose tissue-derived mesenchymal stem cells.;　2013/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Murata D, Tokunaga S, Tamura T, Kawaguchi H, Fujiki M, Miyoshi N, Nakayama K, Misumi K
  
• Spheroids based scaffold-free tissue engineering for cardiovascular regeneration.;　2012/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Noguchi R, Nakayama K, Tamura T, Syomura M, Kamohara K, Furukawa K, Oyama J, Node K, Morita S
  
• Fabrication of tissue engineered pulsatile 3-dimensional scaffold-free cardiac tissue from embryonic stem cells.;　2011/04
  ANNOUNCEMENT INFO.;　International society for Heart Lung Transplanation 31st Annual Meeting and Scientific Sessions (April 13-16, 2011 San Diego, U.S.A.)
  AUTHOR;　Noguchi R, Nakayama K, Ishihara K, Murata Y, Node K, Morita S
  
• Osteo-Chondral regeneration by High Density Adipose Derived Mesenchymal stem cell scaffold free Autologous constructs;　2011/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Nakayama K
  

Other Lectures

• Scaffold-free 3D tissue & organ fabrication by bio-3D printer.;　2016/03
  ANNOUNCEMENT INFO.;　Seminar at Indiana University-Purdue University & Indiana University School of Medicine (Mar.8, 2016,U.S.A.)
  AUTHOR;　Nakayama K.
  
• Scaffold-free 3D tissue & organ fabrication by bio-3D printer.;　2016/03
  ANNOUNCEMENT INFO.;　International Seminar at Colorado State University (Mar. 7, 2016 ,U.S.A.)
  AUTHOR;　Nakayama K.
  
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery;　2015/02
  ANNOUNCEMENT INFO.;　Cleveland Clinic, Ohio, U.S.A.
  AUTHOR;　Nakayama K
  

Application of Intellectual Property Rights

• CULTURE APPARATUS FOR USE IN STUDIES ON DRUG DEVELOPMENT;　2023/02
  ANNOUNCEMENT INFO.;　Pat.No.: P7227653, Application No: P2021-507437, Registration date: 2/14/2023, Issue date:2/22/2023
  AUTHOR;　NAKAYAMA Koichi
  
• METHOD FOR MANUFACTURING LUMINAL STRUCTURE;　2022/08
  ANNOUNCEMENT INFO.;　Pat.No.: P7126732, Application No: P2021-507436, Registration date: 8/19/2022, Issue date: 8/29/2022
  AUTHOR;　NAKAYAMA Koichi
  
• CULTURE APPARATUS FOR USE IN STUDIES ON DRUG DEVELOPMENT;　2020
  ANNOUNCEMENT INFO.;　International Applicaion No.:PCT/JP2014/058152, International Pub.No.WO/2014/148647, Filing date: 3/13/2020, International publication date: 9/24/2020
  AUTHOR;　NAKAYAMA Koichi
  
• METHOD FOR MANUFACTURING LUMINAL STRUCTURE;　2020
  ANNOUNCEMENT INFO.;　International Applicaion No.:PCT/JP2020/012567, International Pub.No.: WO/2020/189792, Filing date: 3/13/2020, International publication date: 9/24/2020
  AUTHOR;　NAKAYAMA Koichi
  
• 細胞培養用治具;　2015
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Liver Tissue Spheroid;　2014/03
  ANNOUNCEMENT INFO.;　Application No. 2013-56835(P2013-56835) dated 2013/3/19 International Applicaion No.PCT/JP2014/058152 Pub.No.WO/2014/148647
  AUTHOR;　Yanagi Y, Tamura T, Nakayama K, Taguchi T
  
• Cardiac or Vascular Tissue Spheroid;　2013
  ANNOUNCEMENT INFO.;　International Application No. PCT/JP2013/079478 Pub. No. WO/2014/141528 USA Application No.14/776,101 Europe Application No.13878105.9 　China Application No.201380074463.6
  AUTHOR;　Noguchi R, Tamura T, Nakayama K, Morita S, Node K
  
• Debubbling Device in Automated Cell Handling Robot;　2012
  ANNOUNCEMENT INFO.;　Application No. 2012-557979 (dated 2012/2/15) Registered Patent Number 5999646 International Application No. PCT/JP2012/053460 Pub. No. WO/2012/111684
  AUTHOR;　Nakayama K, Shimoto K
  
• Cell Structure Production Device;　2011
  ANNOUNCEMENT INFO.;　Application No. 2011-140111 Pub. No.2013-005751 Registered No. 5896104 on 2016/3/11 Expired on 2031/6/24 International Application No.PCT/JP2012/065568 Pub No. WO/2012/176751
  AUTHOR;　Nakayama K, Yoneda K, Sakamoto M, Koshida I, Shomura M, Fukamura I
  
• Device for Manufacturing Supporting Body for Cell Structure;　2011
  ANNOUNCEMENT INFO.;　Application No.2013-544343 International Application No.PCT/JP2012/079800 Pub. No.WO2013/073672
  AUTHOR;　Nakayama K
  
• Transplant Guiding Part and Transplant Tool;　2011
  ANNOUNCEMENT INFO.;　Application No. 2011-023348 Registered Patent No.5769334 Pub No.2012-161433 International Application No. PCT/JP2012/052475 Pub. No. WO/2012/105680
  AUTHOR;　Nakayama K
  
• Therapeutic Agent for Arthropathy for Intraarticular Administration;　2009
  ANNOUNCEMENT INFO.;　Application No.2009-509313 International Application No.PCT/JP2008/056736 Pub. No.WO2008/123602
  AUTHOR;　Iwamoto Y, Matsuda S, Nakayama K, Akasaki Y, Fukagawa S
  
• Method for Production of Three-Dimensional Structure of Cells;　2009
  ANNOUNCEMENT INFO.;　Application No.2009-509335 International application No.PCT/JP2008/056826 International Pub. No.WO2008/123614
  AUTHOR;　Koga T, Nagasato S, Iwamoto Y, Nakayama K
  
• Depth Adjusting Drill;　2007
  ANNOUNCEMENT INFO.;　Application No.2007-045972 Pub. No. 2008-207276
  AUTHOR;　Iwamoto Y, Nakayama K, Okada T
  
• Device for Cell Transplantation;　2006
  ANNOUNCEMENT INFO.;　Application No.2006-172069 Pub.No.2008-000301 International Application No.PCT/JP2007/075343 Pub.No.WO2009/081503　
  AUTHOR;　Iwamoto Y, Miura H, Tanaka K, Matsuda S, Nakayama K
  
• Method of Constructing Artificial Joint;　2005
  ANNOUNCEMENT INFO.;　Application No.2005-512607 International Application No.PCT/JP2004/011391 Pub. No.WO2005/011765
  AUTHOR;　Iwamoto Y, Nakayama K, Tanaka K, Matsuda S
  
• Plate for Recovering Biomaterial;　2004
  ANNOUNCEMENT INFO.;　Application No.2004-081577 Pub.No.2005-261365
  AUTHOR;　Iwamoto Y, Tanaka K, Matsuda S, Nakayama K
  

Dictionary of Compilation, Creating Database

• Editorial Board, Special Issue: Biofabrication with Spheroid and Organoid Materials, Engineered biomaterials to guide spheroid formation, function, and fabrication into 3D tissue constructs, 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration, 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration, Bioprinting of hair follicle germs for hair regenerative medicine, All-aqueous printing of viscoelastic droplets in yield-stress fluids, Hybrid spheroid microscaffolds as modular tissue units to build macro-tissue assemblies for tissue engineering, Hyaluronic acid methacrylate/pancreatic extracellular matrix as a potential 3D printing bioink for constructing islet organoids, Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique, Engineering bone-forming biohybrid sheets through the integration of melt electrowritten membranes and cartilaginous microspheroids, Mathematical and computational models in spheroid-based biofabrication, Building a tissue: Mesenchymal and epithelial cell spheroids mechanical properties at micro- and nanoscale, 3D microengineered vascularized tumor spheroids for drug delivery and efficacy testing, Bone beads enveloped with vascular endothelial cells for bone regenerative medicine, Bone beads enveloped with vascular endothelial cells for bone regenerative medicine, Corrigendum to ‘3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration’ [Acta Biomaterialia (2022)];　2023/07
  ANNOUNCEMENT INFO.;　Biofabrication with Spheroid and Organoid Materials Edited by Mark Skylar-Scott, Heidi Declercq, Koichi Nakayama, 165, 1-200
  AUTHOR;　Koichi Nakayama
  

Review Articles

• Nerve regeneration using the Bio 3D nerve conduit fabricated with spheroids ;　2022/12
  ANNOUNCEMENT INFO.;　J Artif Organs, 25, 4, 289-297
  AUTHOR;　*Ryosuke Ikeguchi, Tomoki Aoyama, Mai Tanaka, Takashi Noguchi, Maki Ando, Koichi Yoshimoto, Daichi Sakamoto, Terunobu Iwai, Yudai Miyazaki, Shizuka Akieda, Makoto Ikeya, Koichi Nakayama, Shuichi Matsuda
  
• Scaffold-based and scaffold-free cardiac constructs for drug testing ;　2021/07
  ANNOUNCEMENT INFO.;　Biofabrication, 13, 4
  AUTHOR;　*Kenichi Arai, Takahiro Kitsuka, Koichi Nakayama
  
• Pre-clinical study of human cell-based vascular graft using a novel operational immunodeficient pig model;　2020/07
  ANNOUNCEMENT INFO.;　Organ Biology, 27, 2, 141-148
  AUTHOR;　○Manabu Itoh, Kumika Matsubayashi, Koichi Nakayama, Eiji Kobayashi
  
• Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED):a promising new treatment in pediatric surgery ;　2019/04
  ANNOUNCEMENT INFO.;　Surg Today. , 49, 4, 316-322
  AUTHOR;　*Taguchi T, Yanagi Y, Yoshimaru K, Xiu-Ying Zhang, Matsuura T, Nakayama K, Kobayashi E, Yamaza H, Nonaka K, Ohga S,Yamaza T
  
• A definition of bioinks and their distinction from biomaterial inks;　2018
  ANNOUNCEMENT INFO.;　Biofabrication, 11, 1
  AUTHOR;　J Groll,、JA Burdick、D-W Cho、B Derby、M Gelinsky、SC Heilshorn、T Jungst, J Malda,、VA Mironov、K Nakayama, A Ovsianikov, W Sun, S Takeuchi, J J Yoo andT B F Woodfield
  
• Scaffold-Free Biofabrication;　2017/06
  ANNOUNCEMENT INFO.;　LIVE 3D Printing and Biofabrication, 1-20
  AUTHOR;　Verissimo A.R, Nakayama K.
  

Invited Lecture, Special Lecture

• Scaffold-free Bio-3D Printing for Solid organ fabrication;　2023/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Nakayama K
  
• バイオ3Ｄプリンタを用いた臓器再生への取り組み;　2023/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 臓器再生を目指したバイオ3Dプリンタの開発とその応用;　2023/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• バイオ3Ｄプリンタを用いた臓器再生への取り組み;　2023/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• バイオ３Dプリンタを用いた臓器再生;　2023/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• バイオ３Dプリンタを用いた骨/軟骨組織再生の試み;　2023/05
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• The Kenzan Method: from Bench to Bedside;　2022/09
  ANNOUNCEMENT INFO.;　ACTO2022 Congress (Hybrid format), 2022, 9,22-24(onsite and online), Keynote Speech 2
  AUTHOR;　Nakayama K
  
• Kenzan Method from Academia to Industry;　2022/09
  ANNOUNCEMENT INFO.;　Biofabrication2022, 2022, 9,25-28
  AUTHOR;　Nakayama K
  
• PROGRESS AND FUTURE PROSPECTS OF CLINICAL RESEARCH ON SCAFFOLD-FREE BIOFABRICATION BY THE KENZAN METHOD;　2022
  ANNOUNCEMENT INFO.;　3DBB II INTERNATIONAL DIGITAL CONGRESS ON BIOFABRICATION AND 3D BIOPRINTING,2022, 3,23-25
  AUTHOR;　Nakayama K
  
• History of the Kenzan method:from bemch to bedside;　2021/06
  ANNOUNCEMENT INFO.;　Biofabrication seminar series(WEB holding), 2021, 6,17
  AUTHOR;　Nakayama K
  
• Progress and future prospects of clinical research on scaffold-free Biofabricantion by the Kenzan method;　2021
  ANNOUNCEMENT INFO.;　2021 6th TERMIS World Congress, 2021,11,15-19
  AUTHOR;　Nakayama K
  
• Scaffold-free Bio-3D printing for Solid organ fabricatio;　2019/07
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Scaffold-free bio-3D printing for solid organ fabrication;　2018/10
  ANNOUNCEMENT INFO.;　The 9th Asian Cellular Therapy Organization Meeting (ACTO 2018), 2018.10.26-28
  AUTHOR;　Koichi Nakayama
  
• Bioassembly of cell spheroids: moving towards the clinic.;　2018/10
  ANNOUNCEMENT INFO.;　Biofabrication 2018 Wurzburg, 2018.10.28-31
  AUTHOR;　Koichi Nakayama
  
• Scaffold-Free Bio-3D Printing for Solid Organ Fabrication;　2018/03
  ANNOUNCEMENT INFO.;　2018 PPSSC (11th Pan Pacific Symposium on Stem Cells and Cancer Research) (March 23-25, 2018, HUARIEN, TAIWAN)
  AUTHOR;　Nakayama K.
  
• Introduction of Scaffold-Free Bio 3D Printer for Organ Regeneration.;　2017/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Nakayama K.
  
• Development and therapeutic application of Scaffold-free 3D tissue and Organ fabrication by Bio-3D printer;　2017/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Scaffold-free bio-3D printing for solid organ fabrication.;　2017/05
  ANNOUNCEMENT INFO.;　Printing the future of therapeutics in 3D(May.03-05,2017,Canada)
  AUTHOR;　Nakayama K.
  
• Development of scaffold free 3D tissue & organ fabrication by bio-3D printer.;　2015/11
  ANNOUNCEMENT INFO.;　Biofabrication 2015 (Nov. 7 - 11, 2015 Utrecht, Netherlands)
  AUTHOR;　Nakayama K
  
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery.;　2015/08
  ANNOUNCEMENT INFO.;　2015 Fourteenth Wu Ta-You Science Camp (Aug.3 - 7, 2015 Taiwan)
  AUTHOR;　Nakayama K
  
• Development of scaffold-free 3D tissue & organ fabrication by bio-3D printer.;　2015/08
  ANNOUNCEMENT INFO.;　6th Meeting of Asian Cellular Therapy Organization (Aug. 20 - 22, 2015 Korea)
  AUTHOR;　Nakayama K
  
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery;　2014/10
  ANNOUNCEMENT INFO.;　International Conference on Bioprinting and Biofabrication (Oct.21-22, 2014 Moscow, Russian Federation)
  AUTHOR;　Nakayama K
  
• A New Approach for 3D Tissue & Organ Fabrication Inspired from Orthopedic Surgery.;　2014/07
  ANNOUNCEMENT INFO.;　International Bioprinting Congress, Singapore (2014 July Singapore)
  AUTHOR;　Nakayama K
  
• A new approach for 3D tissue & organ fabrication inspired from orthopedic surgery.;　2014/05
  ANNOUNCEMENT INFO.;　Jikei symposium for Frontier in Cardiovascular Regulation and Regeneration 2014.5 Tokyo)
  AUTHOR;　Ｎakayama K
  
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery;　2013/11
  ANNOUNCEMENT INFO.;　MHS2013& Micro-Nano Excellent Graduate School (November 12, 2013 Nagoya）
  AUTHOR;　Nakayama K
  
• Construction of scaffold-free three dimensional liver tissue by spheroid fusion using the bio 3D printer.;　2013/09
  ANNOUNCEMENT INFO.;　The 24th Fukuoka International Symposium on Pediatric/Maternal-Child Health research. (Sep., 2013 Fukuoka, Japan)
  AUTHOR;　Nakayama K
  
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery.;　2012/09
  ANNOUNCEMENT INFO.;　TERMIS WC　 (September 5, 2012 Wien, Austria)
  AUTHOR;　Nakayama K
  
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery.;　2012/09
  ANNOUNCEMENT INFO.;　IBS 2012 (September 20, 2012 Tegu, Korea)
  AUTHOR;　Nakayama K
  
• A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery.;　2012/01
  ANNOUNCEMENT INFO.;　The 100th iCeMS Seminar (January 17, 2012 Kyoto, Japan)
  AUTHOR;　Nakayama K
  
• Development of scaffold-free bio rapid prototyping system;　2011/10
  ANNOUNCEMENT INFO.;　Pusan cell therapy symposium (October 18, 2011 Pusan Korea)
  AUTHOR;　Nakayama K
  
• Development of scaffold-free bio rapid prototyping system.;　2011/10
  ANNOUNCEMENT INFO.;　International Conference on Biofabrication 2011 (October 5-8, 2011 Toyama, Japan) Keynote Lecture
  AUTHOR;　Nakayama K
  
• Osteo-chondral regeneration by Adipose derived High Density Mesenchymal stem cell scaffold free Autologous Constructs;　2011/09
  ANNOUNCEMENT INFO.;　1st Seoul St. Mary Hospital Cell Therapy Center Symposium (September 2-3, 2011 Seoul, Korea)
  AUTHOR;　Nakayama K
  
• Bio-rapd prototyping project: A simple method to build living 3 D micro patterned cell construct ex vivo without scaffold.;　2010/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Nakayama Koichi
  
• Osteo-chondral regeneration by High Density Mesenchymal stem cell scaffold free Autologous Constructs;　2010/10
  ANNOUNCEMENT INFO.;　International Society for Cellular Therapy (October 17-20, 2010 Miyazaki)
  AUTHOR;　Nakayama K
  
• Recent developments in mesenchymal stem cell growth and applications;　2010/09
  ANNOUNCEMENT INFO.;　Swiss Institute of Cell Therapies, Geneve, Switzerland
  AUTHOR;　Nakayama K
  
• Recent developments in mesenchymal stem cell growth and applications.;　2010/09
  ANNOUNCEMENT INFO.;　Swiss Institute of Cell Therapies, Geneve, Switzerland
  AUTHOR;　Nakayama K
  
• Bio-rapid prototyping project: A simple method to build living 3D micro patterned cell construct ex vivo without scaffold.;　2010/01
  ANNOUNCEMENT INFO.;　JUMBA　(January 9-15, 2010 San Francisco, CA USA)
  AUTHOR;　Nakayama K
  
• Overview of cartilage tissue engineering.;　2007/09
  ANNOUNCEMENT INFO.;　The 15th Triennial Congress of Asia Pacific Orthopaedic Association (Sept. 9-13, 2007, Seoul, Korea)
  AUTHOR;　Nakayama K, Matsuda S, Iwamoto Y.