Detailed Information

Research Field/Keywords for Research Field

• Animal Reproduction, Embryo Development, Somatic Cell Nuclear Transfer, Epigenetics

Education

• 2002/03, Graduated
• 2004/03, Master Course, Completed
• 2007/03, Doctor Course, Completed

Employment Experience

• 2004/04 - 2007/03 Research Fellow
• 2004/09 - 2004/12
• 2007/04 - 2011/03 Research Fellow
• 2011/04 -  *  Associate Professor, Applied Biological Sciences, Faculty of Agriculture, Saga University
• 2012/04 - 9999/99 Associate Professor

Field of Specialization

• Animal production science, Integrative animal science, Developmental biology

Awards

• 日本畜産学会奨励賞 （2012/03）

Research Topics and Results

• Attenuation of endoplasmic reticulum stress improves in vitro growth and subsequent maturation of bovine oocytes 2024/10
• Antioxidant sericin averts the disruption of oocyte-follicular cell communication triggered by oxidative stress 2024/02
• The strong anti-hyaluronidase effect of ellagic acid markedly decreases polyspermy during in vitro fertilization, resulting in sustainment of the developmental potency in porcine oocytes 2024/02
• Antifreeze protein type III addition to freezing extender comprehensively improves post-thaw sperm properties in Okinawan native Agu pig 2023/04
• Addition of l-carnitine to the freezing extender improves post-thaw sperm quality of Okinawan native Agu pig 2022/08
• Effect of E-64 supplementation during in vitro maturation on the developmental competence of bovine OPU-derived oocytes 2022/02
• Endoplasmic reticulum stress attenuation promotes bovine oocyte maturation in vitro 2020/04
• Role of endoplasmic reticulum stress on developmental competency and cryo-tolerance in bovine embryos 2020/01
• Efficient in vitro embryo production using in vivo-matured oocytes from superstimulated Japanese Black cows 2019/04
• Normal DNA methylation status in sperm from a somatic cell cloned bull and their fertilized embryos 2018/10
• Simple separation of good quality bovine oocytes by using a microfluidic device 2018/09
• 暑熱ストレスが経膣採卵により採取されたウシ卵丘－卵母細胞複合体の品質に及ぼす影響 2018/09
• Sericin enhances the developmental competence of heat-stressed bovine embryos 2018/08
• Heat-shock-induced cathepsin B activity during IVF and culture compromises the developmental competence of bovine embryos 2018/07
• Live births from artificial insemination of microfluidic-sorted bovine spermatozoa characterized by trajectories correlated with fertility 2018/04
• Different thermotolerance in in-vitro-produced embryos derived from different maternal and paternal genetic backgrounds 2017/12
• 沖縄在来ブタアグーの精液輸送時ならびに精子凍結時におけるトコフェロールとアスコルビン酸の同時処理による凍結融解精子性状の改善効果 2017/09
• Epigenetic analysis of bovine parthenogenetic embryonic fibroblasts 2017/08
• Comparing spatial expression dynamics of bovine blastocyst under three different procedures: in-vivo, in-vitro derived, and somatic cell nuclear transfer embryos 2015/11
• Heat stress during in vitro fertilization decreases fertilization success by disrupting anti-polyspermy systems of the oocytes 2015/01
• Cathepsin B activity has a crucial role in the developmental competence of bovine COCs exposed to heat-shock during in vitro maturation. 2013/10
• Transcriptional wiring for establishing cell lineage specification at the blastocyst stage in cattle. 2013/06
• Improvement of the post-thaw qualities of Okinawan native Agu pig spermatozoa frozen in an extender supplemented with anti-apoptotic PTD-FNK protein. 2012/10
• Effect of summer heat environment on body temperature, estrous cycles and blood antioxidant levels in Japanese Black cow 2012/05
• DNA methylation analysis on satellite I region in blastocysts obtained from somatic cell cloned cattle. 2011/08
• Effects of downregulating DNA methyltransferase 1 mRNA by RNA interference on DNA methylation status of satellite I region and in vitro development of bovine somatic cell nuclear transfer embryos. 2011/07
• Intracellular cathepsin B activity is inversely correlated with the quality and developmental competence of bovine preimplantation embryos. 2010/12
• Anomalous oxygen consumption in porcine somatic cell nuclear transfer embryos. 2010/08
• Cathepsin B activity is related to the quality of bovine cumulus oocyte complexes and its inhibition can improve their developmental competence. 2010/05
• Early metaphase II oocytes treated with dibutyryl cyclic adenosine monophosphate provide suitable recipient cytoplasm for the production of miniature pig somatic cell cloned embryos. 2010/02
• Gene Silencing of DNA Methyltransferases by RNA Interference in Bovine Fibroblast Cells. 2010/02
• Acetylation Level of Histone H3 in Early Embryonic Stages Affects Subsequent Development of Miniature Pig Somatic Cell Nuclear Transfer Embryos. 2009/12
• Difference in sensitivity to culture condition between in vitro fertilized and somatic cell nuclear transfer embryos in pigs. 2009/06
• Birth of somatic cell nuclear transfer (SCNT)-cloned miniature piglet following co-transfer of parthenogenetic embryos. 2009/03
• Heat shock-derived reactive oxygen species induce embryonic mortality in in vitro early stage bovine embryos. 2008/09
• Production of viable cloned miniature pig embryos using oocytes derived from domestic pig ovaries. 2008/06
• Effect of cytochalasins B and D on the developmental competence of somatic cell nuclear transfer embryos in miniature pigs. 2008/05
• Induction of estrus in pubertal miniature gilts. 2008/01
• Effect of activation treatments on actin filament distribution and in vitro development of miniature pig somatic cell nuclear transfer embryos. 2007/08
• Caffeine promotes premature chromosome condensation formation and in vitro development in porcine reconstructed embryos via a high level of maturation promoting factor activity during nuclear transfer. 2005/09

Original Articles

• Attenuation of endoplasmic reticulum stress improves in vitro growth and subsequent maturation of bovine oocytes;　2024/10
  ANNOUNCEMENT INFO.;　Theriogenology, 228, 54-63
  AUTHOR;　Md Nuronnabi Islam, Fumio Ebara, Kokoro Kawasaki, Toshihiro Konno, Hideki Tatemoto, Ken-Ichi Yamanaka
  
• Antioxidant sericin averts the disruption of oocyte-follicular cell communication triggered by oxidative stress;　2024/02
  ANNOUNCEMENT INFO.;　Molecular Human Reproduction, 30, 2, gaae001
  AUTHOR;　Khatun Hafiza, Ken-ichi Yamanaka, Satoshi Sugimura
  
• The strong anti-hyaluronidase effect of ellagic acid markedly decreases polyspermy during in vitro fertilization, resulting in sustainment of the developmental potency in porcine oocytes;　2024/02
  ANNOUNCEMENT INFO.;　Theriogenology, 215, 95-102
  AUTHOR;　Kawasaki K, Hirai M, Ishiki Y, Nagahama A, Konno T, Yamanaka K, Tatemoto H
  
• Antifreeze protein type III addition to freezing extender comprehensively improves post-thaw sperm properties in Okinawan native Agu pig;　2023/04
  ANNOUNCEMENT INFO.;　Animal Reproduction Science, 252, 107232
  AUTHOR;　Masuda Y, Kheawkanha T, Nagahama A, Kawasaki K, Konno T, Yamanaka K, Tatemoto H
  
• Addition of l-carnitine to the freezing extender improves post-thaw sperm quality of Okinawan native Agu pig;　2022/08
  ANNOUNCEMENT INFO.;　Theriogenology, 188, 1-7
  AUTHOR;　Hideki Tatemoto, Naoto Osokoshi, Moe Hirai, Yusuke Matsuda, Toshihiro Konno, Kenichi Yamanaka
  
• Effect of E-64 supplementation during in vitro maturation on the developmental competence of bovine OPU-derived oocytes;　2022/02
  ANNOUNCEMENT INFO.;　Genes, 13, 324
  AUTHOR;　Ahmed Z. Balboula, Mansour Aboelenain, Miki Sakatani, Ken-Ichi Yamanaka, Hanako Bai, Takahiro Shirozu, Manabu Kawahara, Abd Elraouf O. Hegab, Samy M. Zaabel, Masashi Takahashi
  
• Gene expression of bovine endometrial epithelial cells cultured in matrigel;　2021/04
  ANNOUNCEMENT INFO.;　Cell and Tissue Research, 385, 1, 265-275
  AUTHOR;　Daichi Nishino, Ai Kotake, Chi Sun Yun, Al‑Nur Md. Iftekhar Rahman, Mohamed El‑Sharawy, Ken‑ichi Yamanaka, M. A. M. Yahia Khandoker, Nobuhiko Yamauchi
  
• Endoplasmic reticulum stress attenuation promotes bovine oocyte maturation in vitro;　2020/04
  ANNOUNCEMENT INFO.;　Reproduction, 159, 4, 361-370
  AUTHOR;　Hafiza Khatun, Yasuhiko Wada, Toshihiro Konno, Hideki Tatemoto, Ken-ichi Yamanaka
  
• Role of endoplasmic reticulum stress on developmental competency and cryo-tolerance in bovine embryos;　2020/01
  ANNOUNCEMENT INFO.;　Theriogenology, 142, 131-137
  AUTHOR;　Hafiza Khatun, Yusuke Ihara, Kota Takakura, Junki Egashira,Yasuhiko Wada, Toshihiro Konno, Hideki Tatemoto, Ken-ichi Yamanaka
  
• Bovine sperm selection procedure prior to cryopreservation for improvement of post-thawed semen quality and fertility;　2019/11
  ANNOUNCEMENT INFO.;　Journal of Animal Science and Biotechnology, 10, 91
  AUTHOR;　Maria Portia B. Nagata, Junki Egashira, Naoto Katafuchi, Kenji Endo, Kazuko Ogata, Kenichi Yamanaka, Tadayuki Yamanouchi, Hideo Matsuda, Yutaka Hashiyada, Kenichi Yamashita
  
• Efficient in vitro embryo production using in vivo-matured oocytes from superstimulated Japanese Black cows;　2019/04
  ANNOUNCEMENT INFO.;　The Journal of Reproduction and Development, 65, 2, 183-190
  AUTHOR;　Junki Egashira, Yusuke Ihara, Hafiza Khatun, Yasuhiko Wada, Toshihiro Konno, Hideki Tatemoto, Ken-ichi Yamanaka
  
• Normal DNA methylation status in sperm from a somatic cell cloned bull and their fertilized embryos;　2018/10
  ANNOUNCEMENT INFO.;　Animal Science Journal, 89, 10, 1406-1414
  AUTHOR;　Ken-ichi Yamanaka, Kyoko Yamashita, Hafiza Khatun, Yasuhiko Wada, Hideki Tatemoto, Miki Sakatani, Naoki Takenouchi, Masashi Takahashi, Shinya Watanabe
  
• Simple separation of good quality bovine oocytes by using a microfluidic device;　2018/09
  ANNOUNCEMENT INFO.;　Scientific Reports, 8, 14273
  AUTHOR;　Wataru Iwasaki, Kenichi Yamanaka, Daisuke Sugiyama, Yuki Teshima, Maria Portia Briones-Nagata, Masatoshi Maeki, Kenichi Yamashita, Masashi Takahashi, Masaya Miyazaki
  
• 暑熱ストレスが経膣採卵により採取されたウシ卵丘－卵母細胞複合体の品質に及ぼす影響;　2018/09
  ANNOUNCEMENT INFO.;　, 62, 2, 111-119
  AUTHOR;　
  
• Sericin enhances the developmental competence of heat-stressed bovine embryos;　2018/08
  ANNOUNCEMENT INFO.;　Molecular Reproduction and Development, 85, 8-9, 696-708
  AUTHOR;　Hafiza Khatun, Junki Egashira, Miki Sakatani, Naoki Takenouchi, Hideki Tatemoto, Yasuhiko Wada, Ken-ichi Yamanaka
  
• Heat-shock-induced cathepsin B activity during IVF and culture compromises the developmental competence of bovine embryos;　2018/07
  ANNOUNCEMENT INFO.;　Theriogenology, 114, 293-300
  AUTHOR;　Ken-ichi Yamanaka, Hafiza Khatun, Junki Egashira, AhmedZ Balboula, Hideki Tatemoto, Miki Sakatani, Naoki Takenouchi, Yasuhiko Wada, Masashi Takahashi
  
• Live births from artificial insemination of microfluidic-sorted bovine spermatozoa characterized by trajectories correlated with fertility;　2018/04
  ANNOUNCEMENT INFO.;　Proceedings of the National Academy of Sciences of the United States of America, 115, 14, 3087-3096
  AUTHOR;　Maria Portia B. Nagata, Kenji Endo, Kazuko Ogata, Kenichi Yamanaka, Junki Egashira, Naoto Katafuchi, Tadayuki Yamanouchi, Hideo Matsuda, Yuki Goto, Miki Sakatani, Takuo Hojo, Hirofumi Nishizono, Kenji Yotsushima, Naoki Takenouchi, Yutaka Hashiyada, Kenichi Yamashita
  
• Different thermotolerance in in-vitro-produced embryos derived from different maternal and paternal genetic backgrounds;　2017/12
  ANNOUNCEMENT INFO.;　Animal Science Journal, 88, 12, 1934-1942
  AUTHOR;　M Sakatani, K Yamanaka, AZ Balboula, M Takahishi
  
• 沖縄在来ブタアグーの精液輸送時ならびに精子凍結時におけるトコフェロールとアスコルビン酸の同時処理による凍結融解精子性状の改善効果;　2017/09
  ANNOUNCEMENT INFO.;　, 60, 2, 111-120
  AUTHOR;　
  
• Epigenetic analysis of bovine parthenogenetic embryonic fibroblasts;　2017/08
  ANNOUNCEMENT INFO.;　The Journal of Reproduction and Development, 63, 4, 359-363
  AUTHOR;　Masahiro Kaneda, Masashi Takahishi, Ken-ichi Yamanaka, Koji Saito, Masanori Taniguchi, Satoshi Akagi, Shinya Watanabe, Takashi Nagai
  
• 烏骨鶏選抜集団第５世代における８番染色体上のDNAマーカーと生産形質との関連性;　2016/10
  ANNOUNCEMENT INFO.;　, 53, J2, J45-J49
  AUTHOR;　
  
• Comparing spatial expression dynamics of bovine blastocyst under three different procedures: in-vivo, in-vitro derived, and somatic cell nuclear transfer embryos;　2015/11
  ANNOUNCEMENT INFO.;　The Japanese Journal of Veterinary Research, 63, 4, 159-171
  AUTHOR;　Nagatomo H, Akizawa H, Sada A, Kishi Y, Yamanaka K, Takuma T, Sasaki K, Yamauchi N, Yanagawa Y, Nagano M, Kono T, Takahashi M, Kawahara M
  
• Generation of aminoterminally truncated, stable types of bioactive bovine and porcine fibroblast growth factor 4 in Escherichia coli;　2015/04
  ANNOUNCEMENT INFO.;　Biotechnology and Applied Biochemistry, 62, 2, 164-172
  AUTHOR;　Sugawara S, Ito T, Sato S, Sato Y, Sasaki A, Fukuda T, Yamanaka K, Sakatani M, Takahashi M, Kobayashi M
  
• Heat stress during in vitro fertilization decreases fertilization success by disrupting anti-polyspermy systems of the oocytes;　2015/01
  ANNOUNCEMENT INFO.;　Molecular Reproduction and Development, 82, 1, 36-47
  AUTHOR;　Sakatani　M, Yamanaka K, Balboula AZ, Takenouchi N, Takahashi M
  
• Relationship between production traits and DNA markers on chromosome Z in the 5th generarion of selection program of Silky fowl;　2014/09
  ANNOUNCEMENT INFO.;　Journal of Warm Regional Society of Animal Science, 57, 2, 115-122
  AUTHOR;　Rahman MD, Nishiyama Y, Yamanaka K, Anann K, Wada Y
  
• Simple density-based particle separation in a microfluidic chip.;　2014
  ANNOUNCEMENT INFO.;　Anatical Methods, 6, 1, 308-311
  AUTHOR;　Sugiyama D, Teshima Y, Yamanaka K, Briones-Nagata M, Maeki M, Yamashita K, Takahashi M, Miyazaki M
  
• Expression and Regulation of Foxa2 in the Rat Uterus during Early Pregnancy;　2014
  ANNOUNCEMENT INFO.;　Journal of Reproduction and Development
  AUTHOR;　Yamagami K, Yamauchi N, Kubota K, Nishimura S, Chowdhury V, Yamanaka K, Takahashi M, Tabata S, Hattori M
  
• Cathepsin B activity has a crucial role in the developmental competence of bovine COCs exposed to heat-shock during in vitro maturation.;　2013/10
  ANNOUNCEMENT INFO.;　Reproduction, 146, 4, 407-417
  AUTHOR;　Balboula AZ, Yamanaka K, Sakatani M, Kawahara M, Hegab AE, Zaabel S, Takahashi M
  
• Transcriptional wiring for establishing cell lineage specification at the blastocyst stage in cattle.;　2013/06
  ANNOUNCEMENT INFO.;　Biology of Reproduction, 88, 6, 1-10
  AUTHOR;　Nagatomo H, Kagawa S, Kishi Y, Takuma T, Sada A, Yamanaka K, Abe Y, Wada Y, Takahashi M, Kono T, Kawahara M
  
• Production of bioactive bovine fibroblast growth factor 4 in E. coli.;　2013/03
  ANNOUNCEMENT INFO.;　Animal Sciecnce Journal, 84, 3, 275-280
  AUTHOR;　Sugawara S, Ito　T, Sato S, Yokoo M, Mori Y, Kasuga K, Kojima I, Fukuda T, Yamanaka K, Sakatani M, Takahashi M, Kobayashi M
  
• Improvement of the post-thaw qualities of Okinawan native Agu pig spermatozoa frozen in an extender supplemented with anti-apoptotic PTD-FNK protein.;　2012/10
  ANNOUNCEMENT INFO.;　Theriogenology, 78, 7, 1446-1455
  AUTHOR;　Shimokawa K, Oshiro R, Yamanaka K, Ashizawa K, Ohta S, Tatemoto H.
  
• Effect of summer heat environment on body temperature, estrous cycles and blood antioxidant levels in Japanese Black cow;　2012/05
  ANNOUNCEMENT INFO.;　Animal Scicence Journal, 83, 5, 394-402
  AUTHOR;　Sakatani M, Balboula A, Yamanaka K, Takahashi M
  
• DNA methylation analysis on satellite I region in blastocysts obtained from somatic cell cloned cattle.;　2011/08
  ANNOUNCEMENT INFO.;　Animal Science Journal, 82, 4, 523-530
  AUTHOR;　Yamanaka K, Kaneda M, Inaba Y, Saito K, Kubota K, Sakatani M, Sugimura S, Imai K, Watanabe S, Takahashi M.
  
• Effects of downregulating DNA methyltransferase 1 mRNA by RNA interference on DNA methylation status of satellite I region and in vitro development of bovine somatic cell nuclear transfer embryos.;　2011/07
  ANNOUNCEMENT INFO.;　Journal of Reproduction and Development, 57, 3, 393-402
  AUTHOR;　Yamanaka K, Sakatani M, Balboula AZ, Sawai K, Takahashi M.
  
• Intracellular cathepsin B activity is inversely correlated with the quality and developmental competence of bovine preimplantation embryos.;　2010/12
  ANNOUNCEMENT INFO.;　Molecular Reproduction and Development, 77, 12, 1031-1039
  AUTHOR;　Balboula AZ, Yamanaka K, Sakatani M, Hegab AE, Zaabel S, Takahashi M.
  
• Anomalous oxygen consumption in porcine somatic cell nuclear transfer embryos.;　2010/08
  ANNOUNCEMENT INFO.;　 Cellular Reprogramming, 12, 4, 463-474
  AUTHOR;　Sugimura S, Yokoo M, Yamanaka K, Kawahara M, Moriyasu S, Wakai T, Nagai T, Abe H, Sato E.
  
• Cathepsin B activity is related to the quality of bovine cumulus oocyte complexes and its inhibition can improve their developmental competence.;　2010/05
  ANNOUNCEMENT INFO.;　Molecular Reproduction and Development, 77, 5, 439-448
  AUTHOR;　Balboula AZ, Yamanaka K, Sakatani M, Hegab AE, Zaabel S, Takahashi M.
  
• Steroidal regulation of Ihh and Gli1 expression in the rat uterus.;　2010/05
  ANNOUNCEMENT INFO.;　Cell and Tissue Research, 340, 2, 389-395
  AUTHOR;　Kubota K, Yamauchi N, Yamagami K, Nishimura S, Goubaru T, Yamanaka K, Woods C, Soh T, Takahashi M, Hattori MA.
  
• Early metaphase II oocytes treated with dibutyryl cyclic adenosine monophosphate provide suitable recipient cytoplasm for the production of miniature pig somatic cell cloned embryos.;　2010/02
  ANNOUNCEMENT INFO.;　Animal Science Journal, 81, 1, 48-57
  AUTHOR;　Sugimura S, Yamanaka K, Wakai T, Kawahara M, Sato E.
  
• Gene Silencing of DNA Methyltransferases by RNA Interference in Bovine Fibroblast Cells.;　2010/02
  ANNOUNCEMENT INFO.;　Journal of Reproduction and Development, 56, 1, 60-67
  AUTHOR;　Yamanaka K, Balboula AZ, Sakatani M, Takahashi M.
  
• Acetylation Level of Histone H3 in Early Embryonic Stages Affects Subsequent Development of Miniature Pig Somatic Cell Nuclear Transfer Embryos.;　2009/12
  ANNOUNCEMENT INFO.;　 Journal of Reproduction and Development, 55, 6, 638-644
  AUTHOR;　Yamanaka K, Sugimura S, Wakai T, Kawahara M, Sato E.
  
• Difference in sensitivity to culture condition between in vitro fertilized and somatic cell nuclear transfer embryos in pigs.;　2009/06
  ANNOUNCEMENT INFO.;　 Journal of Reproduction and Development, 55, 3, 299-304
  AUTHOR;　Yamanaka K, Sugimura S, Wakai T, Kawahara M, Sato E.
  
• Birth of somatic cell nuclear transfer (SCNT)-cloned miniature piglet following co-transfer of parthenogenetic embryos.;　2009/03
  ANNOUNCEMENT INFO.;　Tohoku Journal of Agricultural Research, 59, 3, 51-61
  AUTHOR;　Sugimura S, Yamanaka K, Wakai T, Kawahara M, Tanaka H, Kobayashi J, Kobayashi E, Sato E.
  
• Heat shock-derived reactive oxygen species induce embryonic mortality in in vitro early stage bovine embryos.;　2008/09
  ANNOUNCEMENT INFO.;　 Journal of Reproduction and Development, 54, 6, 496-501
  AUTHOR;　Sakatani M, Yamanaka K, Kobayashi S, Takahashi M.
  
• Production of viable cloned miniature pig embryos using oocytes derived from domestic pig ovaries.;　2008/06
  ANNOUNCEMENT INFO.;　Cloning and Stem Cells, 10, 2, 249-262
  AUTHOR;　Wakai T, Sugimura S, Yamanaka K, Kawahara M, Sasada H, Tanaka H, Ando A, Kobayashi E, Sato E.
  
• Effect of cytochalasins B and D on the developmental competence of somatic cell nuclear transfer embryos in miniature pigs.;　2008/05
  ANNOUNCEMENT INFO.;　 Zygote, 16, 2, 153-159
  AUTHOR;　Sugimura S, Kawahara M, Wakai T, Yamanaka K, Sasada H, Sato E.
  
• Induction of estrus in pubertal miniature gilts.;　2008/01
  ANNOUNCEMENT INFO.;　Animal Reproduction Science, 103, 193-198
  AUTHOR;　Wakai T, Tanaka H, Yamanaka K, Sugimura S, Sasada H, Kawahara M, Kobayashi E, Sato E.
  
• Effect of activation treatments on actin filament distribution and in vitro development of miniature pig somatic cell nuclear transfer embryos.;　2007/08
  ANNOUNCEMENT INFO.;　Journal of Reproduction and Development, 53, 4, 791-800
  AUTHOR;　Yamanaka K, Sugimura S, Wakai T, Shoji T, Kobayashi J, Sasada H, Sato E.
  
• Morphological aspects of porcine embryos reconstructed by somatic cell nuclear transfer;　2007/04
  ANNOUNCEMENT INFO.;　Morphology, 2, 1, 23-27
  AUTHOR;　Wakai T, Kawahara M, Yamanaka K, Hoshino Y, Tomioka I, Sugimura S, Sugawara A, Sato E
  
• Caffeine promotes premature chromosome condensation formation and in vitro development in porcine reconstructed embryos via a high level of maturation promoting factor activity during nuclear transfer.;　2005/09
  ANNOUNCEMENT INFO.;　Reproduction, 130, 3, 351-357
  AUTHOR;　Kawahara M, Wakai T, Yamanaka K, Kobayashi J, Sugimura S, Shimizu T, Matsumoto H, Kim JH, Sasada H, Sato E.
  

Material, Commentary, Editorials, Research Report, A Comprehensive Journal Articles

• ウシ精子における暑熱ストレス耐性に関与する要因解析;　2015/11
  ANNOUNCEMENT INFO.;　, 33, 258-263
  AUTHOR;　
  
• ウシ胚発生過程におけるリソソーム機能に関する研究;　2015/04
  ANNOUNCEMENT INFO.;　, 5, 37-47
  AUTHOR;　
  
• リソソーム酵素活性制御による高温ストレス下でのウシ胚発生改善に関する研究;　2014/11
  ANNOUNCEMENT INFO.;　, 32, 142-147
  AUTHOR;　
  
• 牛における核移植胚作出と胚の品質評価のためのマニュアル：胚の品質評価法;　2011/03
  ANNOUNCEMENT INFO.;　, 9, 28-48
  AUTHOR;　
  
• 体細胞クローン家畜の生産効率の向上につながる基礎的知見 体細胞クローン胚におけるDNAのメチル化制御機構の解明とその評価;　2010/07
  ANNOUNCEMENT INFO.;　, 10, 33-38
  AUTHOR;　
  
• 蛍光試薬を用いた胚盤胞の簡便な染色法;　2010/01
  ANNOUNCEMENT INFO.;　, 32, 1, 13-17
  AUTHOR;　
  

General Lectures

• ER stress inhibitor supports in vitro growth and maturation of bovine oocytes;　2024/01
  ANNOUNCEMENT INFO.;　50th Annual Conference of the International Embryo Technology Society
  AUTHOR;　Md Nuronnabi Islam, M. Moniruzzaman, Ken-ichi Yamanaka
  
• 黒毛和種牛の体内成熟卵子を用いた体外受精において発生培地にタウロウルソデオキシコール酸を添加することで胚盤胞発生率が向上する;　2023/12
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Effect of polysaccharide from Flammulina velutipes on the vitrification of bovine oocytes;　2020/01
  ANNOUNCEMENT INFO.;　46th International Embryo Technology Society
  AUTHOR;　Yusuke Ihara, Kota Takakura, Yasuhiko Wada, Hidehisa Kawahara, Ken-ichi Yamanaka
  
• Inhibition of endoplasmic reticulum stress during in vitro maturation improves the developmental competence of bovine COCs;　2020/01
  ANNOUNCEMENT INFO.;　46th International Embryo Technology Society
  AUTHOR;　Hafiza Khatun, Yusuke Ihara, Kota Takakura, Yasuhiko Wada, Ken-ichi Yamanaka
  
• 魚類由来不凍タンパク質がウシ卵母細胞のガラス化保存成績に及ぼす影響;　2019/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• マイクロ流体デバイスで選別したウシ精子の運動特性と人工授精後の受胎性との関連;　2019/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• エノキタケ由来多糖がウシ卵母細胞ガラス化成績に及ぼす影響;　2019/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• ウシ体外生産胚のガラス化成績向上を目的としたエノキタケ由来不凍多糖添加の検討;　2019/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 体内成熟卵母細胞を用いた体外受精胚の発生動態解析;　2019/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• ウシ初期胚発生過程におけるオートファジー制御が発生能に及ぼす影響;　2019/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Efficient in vitro embryo production system using in vivo matured oocytes from superstimulated Japanese black cows;　2019/01
  ANNOUNCEMENT INFO.;　45th International Embryo Technology Society
  AUTHOR;　
  
• 高品質卵子の簡便で高速な分離デバイス開発;　2018/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 烏骨鶏飼料への乾燥オリーブ葉の添加;　2018/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Inhibition of Endoplasmic Reticulum Stress Improves Developmental Competency and Cryotolerance of Bovine Blastocysts Produced In Vitro;　2018/08
  ANNOUNCEMENT INFO.;　18th Asian Australasian Animal Production Congress
  AUTHOR;　Khatun Hafiza, Yasuhiko Wada, Kenichi Yamanaka
  
• 黒毛和種におけるOPU由来体内成熟卵子を用いた効率的な体外胚生産系の検討;　2017/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• ウシ初期胚発生過程におけるオートファジー解析;　2017/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 乳酸菌製剤添加資料で飼育した白色レグホーンにおける空腸と回腸の遺伝子発現;　2016/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Sericin Supplementation during In Vitro Culture Enhances the Developmental Competence of Heat Stressed Bovine Embryos;　2016/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Khatun Hafiza, Yasuhiko Wada, Kenichi Yamanaka
  
• 鈍性発情牛における行動量、体温測定を用いた発情検出の可能性;　2016/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 乳酸菌製剤入り飼料で飼育したブロイラー小腸のRNA-Seq解析;　2015/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 黒毛和種における発情時の乗駕許容、歩数および体温の様相;　2015/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• ブロイラー飼料への乳酸菌資材の添加が小腸の遺伝子発現に及ぼす影響;　2015/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• CIITA 遺伝子発現の抑制がウシ初期胚発生に与える影響;　2015/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 体外発生時の暑熱ストレスがウシ胚のカテプシンB活性に及ぼす影響;　2014/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 烏骨鶏選抜集団第５世代における８番染色体上のDNAマーカーと生産形質との関連性;　2014/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Relationship between production traits and DNA markers on chromosome Z in the 5th generarion of selection program of Silky fowl;　2013/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Rahman MD. M, Nishiyama Y, Yamanaka K, Anann K, Wada Y
  
• 暑熱ストレスがウシ体外受精胚のカテプシンB活性および発生能に及ぼす影響;　2013/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Effect of RNAi mediated knockdown of Xist on preimplantation and full-term development of bovine cloned embryos.;　2013/07
  ANNOUNCEMENT INFO.;　the Society for the Study of Reproduction
  AUTHOR;　Sawai K, Sakurai N, Inoue K, Fujii T, Hirayama H, Kageyama S, Hashizume T, Yamanaka K, Takahashi M, Ogura A
  
• RNA干渉法を用いたウシ体細胞クローン胚のXist遺伝子発現抑制とその体外発生能;　2013/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 3種のウシに共通する線維芽細胞増殖因子4構造遺伝子の塩基配列の決定，および大腸菌によるウシFGF4タンパク質の生産;　2013/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Density-based particle separation using a microfluidic device;　2012/12
  ANNOUNCEMENT INFO.;　European Conference on Microfluidics
  AUTHOR;　Sugiyama D, Teshima Y, Briones-Nagata MP, Yamanaka K, Takahashi M, Miyazaki M
  
• マイクロ流体デバイスを用いたウシ卵子の密度差分別と品質評価;　2012/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• マイクロ流体デバイスを用いた粒子の密度差分別と卵子分別への応用;　2012/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• 黒毛和種牛，日本短角種牛およびホルスタイン種牛に共通して見い出され，しかも新規な塩基配列を示すウシ線維芽細胞増殖因子4構造遺伝子とその応用;　2012/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Design of microfluidic device for cell sorting and separation of model particles;　2012/06
  ANNOUNCEMENT INFO.;　International Symposium on Microchemistry and Microsystems
  AUTHOR;　Sugiyama D, Teshima Y, Maeki M, Yamanaka K, Takahashi M, Miyazaki M, Maeda H
  
• マイクロ流体デバイスを用いた粒子の密度分別とその応用;　2012/06
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• マイクロ流路デバイスを用いた密度の異なる粒子の低刺激分別と応用;　2012/05
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• ウシ胚盤胞期胚における内部細胞塊および栄養外胚葉の遺伝子発現解析;　2011/09
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• ウシ単為発生胚由来線維芽細胞を用いたマイクロアレイによる新規インプリント遺伝子の探索;　2011/05
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  

Application of Intellectual Property Rights

• 制限酵素の認識配列に依存したDNA部位の検出法;　2009/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  

Review Articles

• 牛胚の初期発生に及ぼす暑熱ストレスの影響;　2009/02
  ANNOUNCEMENT INFO.;　, 645, 2, 2-9
  AUTHOR;　
  
• 牛繁殖性に及ぼす暑熱ストレス;　2009/01
  ANNOUNCEMENT INFO.;　, 21, 1, 9-17
  AUTHOR;　
  
• 体細胞クローン作出におけるエピジェネティクス研究の現状について;　2008/05
  ANNOUNCEMENT INFO.;　, 30, 2, 99-105
  AUTHOR;　
  
• Cryopreservation and in vitro maturation of germinal vesicle stage oocytes of animals for application in assisted reproductive technology.;　2007/08
  ANNOUNCEMENT INFO.;　Reproductive Medicine and Biology, 6, 61-68
  AUTHOR;　Yamanaka K, Aono N, Yoshida H, Sato E.
  
• ミニブタ体細胞クローン個体作出成功に関わる要因解析;　2007/01
  ANNOUNCEMENT INFO.;　, 29, 1, 10-13
  AUTHOR;　
  
• 体の大きさ・顔面形成に関わる遺伝子と新品種開発への応用;　2006/07
  ANNOUNCEMENT INFO.;　, 60, 7, 767-770
  AUTHOR;　
  
• 性格関連遺伝子とイヌにおける性格の人為的制御の可能性;　2006/07
  ANNOUNCEMENT INFO.;　Animal world, 7, 3-5
  AUTHOR;　
  
• 寿命関連遺伝子とイヌにおける寿命操作の可能性;　2006/04
  ANNOUNCEMENT INFO.;　, 60, 4, 449-452
  AUTHOR;　
  
• ヒトES細胞の樹立とその意義;　2005/12
  ANNOUNCEMENT INFO.;　HORMONE FRONTIER IN GYNECOLOGY, 12, 4, 315-326
  AUTHOR;　
  
• Molecular Basis of Meiotic Maturation and Apoptosis of Oocytes, Sperm-Oocyte Interactions and Early Cleavage of Embryos in Mice, Role of Phosphatidylinositol 3-kinase, Mos, Fas-Fas Ligand, Integrin-α6 and MAP Kinase.;　2005/07
  ANNOUNCEMENT INFO.;　YAKHTEH Medical Journal, 7, 2, 98-114
  AUTHOR;　Hoshino Y, Yamanaka K, Tomioka I, Fukunaga N, Abbasi M, Sato E.
  

Invited Lecture, Special Lecture

• Age-dependent changed in DNA methylation levels of spermatozoa and the relationship to their motility and fertility in Japanese Black bulls;　2024/01
  ANNOUNCEMENT INFO.;　50th Annual Conference of the International Embryo Technology Society
  AUTHOR;　Masaya Iwamoto, Kazuki Ohta, Md Nuronnabi Islam, Ken-ichi Yamanaka
  
• 体外生産胚の高品質化に向けた取り組み;　2014/12
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  

Translation and Introduction of Academic Books, Work Overseas

• スキッロ　動物生殖生理学;　2011/04
  ANNOUNCEMENT INFO.;　
  AUTHOR;