1992/04, Doctor Course, Accomplished credits for doctoral program
Employment Experience
1992/04 - 1992/04 Postdoctoral Fellowships of Japan Society for the Promotion of Science
1992/05 - 1997/08 Research Associate, Faculty of Agriculture, Saga University
1993/04 - 1997/09 Research Associate
1997/09 - 2007/03 Associate Professor, Faculty of Agriculture, Saga University
1999/04 - 2007/03 Associate Professor
2007/04 - 2012/10 Associate Professor, Applied Biochemistry and Food Science, Faculty of Agriculture, Saga University
2008/04 - 2009/03 Associate Professor
2012/11 - * Professor, Applied Biochemistry and Food Science, Faculty of Agriculture, Saga University
2012/11 - 9999/99 Professor
Field of Specialization
Aquatic life science, Food science, Aquatic bioproduction science, Applied biochemistry
Research Topics and Results
A unique life cycle transition in the red seaweed Pyropia yezoensis depends on apospory. 2019/08
乾海苔に含まれる多糖含量とポルフィランの性質 2011
Selective Hydrolysis of the 3,6-Anhydrogalactosidic Linkage in Red Algal Galactan: A Combination of Reductive Acid Hydrolysis and Anhydrous Mercaptolysis 2010/09
Interanction of GM2 Activator Protein with Glycosphingolipids. 2003
Structural characterization of the trisaccharide chain from the skin mucus glycoprotein of the rainbow trout, Salmo gairdneri. 2002
Quantitative Anhydrous Mercaptolysis of Algal Galactans Followed by HPLC of Component Sugars. 1999
Anhydrous mercaptolysis of agar: an efficient preparation of 3,6-anhydro-L-galactose diethyl dithioacetal. 1999
A Gas Chromatographic Method for the Sugar Analysis of 3,6-Anhydrogalactose-Containing Algal Galactans. 1998
Interaction of GM2 Activator Protein with Glycosphingolipids. 1997
Characterization of a Deaminated Neuraminic Acid-containing Glycoprotein from the Skin Mucus of the Loach, Misgrunus anguillicaudatus. 1994
Prostaglandin-like Substances, Precursors of Red Pigment, Formed during Autoxidation of Methyl Arachidonate 1988
Original Articles
A unique life cycle transition in the red seaweed Pyropia yezoensis depends on apospory.; 2019/08 ANNOUNCEMENT INFO.; Commun. Biol., 2, 299 AUTHOR; K. Mikami, C. Li, R. Irie, Y. Hama
The fungal 9-methyl-sphingadiene is a novel ligand for both PPAR and GPR120; 2018/05 ANNOUNCEMENT INFO.; J. Food Biochem., e12624 AUTHOR; Esaki S., Nagasawa T., Tanaka T., Tominaga A., Mikami D., Usuki S., Hamajima H., Hanamatsu H., Sakai S., Hama Y., Igarashi Y., Kitagaki H., Mitsutake S.
Phytosphingosine is a novel activator of GPR120; 2018/01 ANNOUNCEMENT INFO.; J Biochem., 10, 1093 AUTHOR; Nagasawa T., Nakamichi H., Hama Y., Higashiyama S., Igarashi Y., Mitsutake S.
The analysis of Δ12-fatty acid desaturase function revealed that two distinct pathways are active for the synthesis of polyunsaturated fatty acids in Thraustochytrium aureum ATCC34304; 2012/06 ANNOUNCEMENT INFO.; Journal of Lipid Research, 53, 6, 1210-1222 AUTHOR; T. Matsuda, K. Sakaguchi, R. Hamaguchi, T. Kobayashia, E. Abe, Y. Hama, M. Hayashi, D. Honda, Y. Okita, S. Sugimoto, N. Okino, M. Ito
Structural features of N-glycans of seaweed glycoproteins: predominant occurrence of high-mannose type N-glycans in marine plants; 2012/06 ANNOUNCEMENT INFO.; Biosci. Biotech. Biochem., 76, 10, 1996-1998 AUTHOR; T. Yoshiie, M. Maeda, M. Kimura, Y. Hama, M. Uchida, Y. Kimura
Inhibitory effect of sulphated polysaccharide porphyran on nitric oxide production in lipopolysaccharide-stimulated RAW264.7 macrophages; 2012 ANNOUNCEMENT INFO.; Journal of Biochemistry, 151, 1, 65-74 AUTHOR; Z. Jiang, Y. Hama, K. Yamaguchi, T. Oda
Increase of Eicosap;entaenoic Acid in Thraustochytrids through Thraustochytrid Ubiquitin Promoter-Driven Expression of a Fatty Acid delta-5 Desaturase Gene; 2011 ANNOUNCEMENT INFO.; Applied and Environmental Microbiology, 77, 11, 3870-3876 AUTHOR; T. Kobayashi, K. Sakaguchi, T. Matsuda, E. Abe, Y. Hama, M. Hayashi, D. Honda, Y. Okita, S. Sugimoto, N. Okino, M. Ito
Molecular cloning of a Pinguiochrysis pyriformis oleate-specific microsomal Δ12-fatty acid desaturase and functional analysis in yeasts and thraustochytrids; 2011 ANNOUNCEMENT INFO.; Journal of Biochemistry, 150, 4, 375-383 AUTHOR; T. Matsuda, K. Sakaguchi, T. Kobayashi, E. Abe, N. Kurano, A. Sato, Y. Okita, S. Sugimoto, Y. Hama, M. Hayashi, N. Okino, M. Ito
Selective Hydrolysis of the 3,6-Anhydrogalactosidic Linkage in Red Algal Galactan: A Combination of Reductive Acid Hydrolysis and Anhydrous Mercaptolysis; 2010/09 ANNOUNCEMENT INFO.; Biosci. Biotechnol. Biochem., 74, 9, 1895-1900 AUTHOR; Yoichiro Hama, Aya Tsuneoka, Ryoji Morita, Osamu Nomoto, Kenshi Yoshinaga, Hideo Hatate, Toshihisa Sumi, Hiroki Nakagawa
The Sulfated Polysaccharide Porphyran Reduces Apolipoprotein B100 Secretion and Lipid Synthesis in HepG2 Cells.; 2009/02 ANNOUNCEMENT INFO.; Biosci. Biotechnol. Biochem., 73, 2, 447-449 AUTHOR; N. Inoue, N. Yamano, K. Sakata, K. Nagao, Y. Hama, T. Yanagita.
Antioxidant property of polyhydroxylated naphthoquinone pigments from shells of purple sea urchin Anthocidaris crassispina.; 2009 ANNOUNCEMENT INFO.; Food Sci. Technol., 42, 1296-1300 AUTHOR; R. Kuwahara, H. Hatate, T. Yuki, H. Murata, R. Tanaka, Y. Hama
A novel fucosyl glycosphingolipid of brine shrimp that is highly sensitive to endoglycoceramidase.; 2009 ANNOUNCEMENT INFO.; Glycobiology, 19, 12, 1446-1451 AUTHOR; Xu, Xu; Horibata, Yasuhiro; Inagaki, Masanori; Hama, Yoichiro; Sakaguchi, Keishi; Goda, Hatsumi M.; Okino, Nozomu; Ito, Makoto.
Elastin peptide receptor-directed monocyte chemotactic polysaccharides derived from seaweed sporophyll and from infectious fungus.; 2008 ANNOUNCEMENT INFO.; Microbial Pathogenesis, 45, 423-424 AUTHOR; Y. Li, H. Nishiura, K. Tokita, Y. Kouike, C. Taniguchi, M. Iwahara, N. Nishino, Y. Hama, M. Asakawa, T. Yamamoto.
Antioxidant activities of phlorotannins isolated from Japanese Laminariaceae.; 2008 ANNOUNCEMENT INFO.; J. Appl. Phycol., 20, 5, 705-711 AUTHOR; T. Shibata, K. Ishimaru, S. Kawaguchi, H. Yoshikawa, Y. Hama.
Evidence for new b1-3 galactosyltransferase activity involved in biosynthesis of unusual N-glycan harboring T-antigen in Apis mellifera.; 2007 ANNOUNCEMENT INFO.; Biosci. Biotech. Biochem., 71, 1111-1114 AUTHOR; Y. Kimura, S. Sakamura, T. Ushijima, Y. Hama, H. Kajiura, K. Fujiyama, K. Okihara, K. Hashimoto, H. Sugimoto, H. Yamada.
Fucosyl-GM1a, an endoglycoceramidase-resistant ganglioside of porcine brain.; 2007 ANNOUNCEMENT INFO.; J. Biochem., 141, 1-7 AUTHOR; X. Xu, H. Monjusho, M. Inagaki, Y. Hama, K. Kuniko; K. Sakaguchi, M. Iwamori, N. Okino, M. Ito
Occurrence of a nonsulfated chondroitin proteoglycan in the dried saliva of Collocalia swiftlets (edible bird's-nest).; 2007 ANNOUNCEMENT INFO.; Glycobiology, 17, 157-164 AUTHOR; H. Nakagawa, Y. Hama, T. Sumi, S.-C. Li, K. Maskos, K. Kalayanamitra, S. Mizumoto, K. Sugahara, Y.-T. Li
Fucosyl-GM1a, an endoglycoceramidase-resistant ganglioside of porcine brain.; 2007 ANNOUNCEMENT INFO.; J. Biochem. (Tokyo), 141, 1, 1-7 AUTHOR; X. Xu, H. Monjusho, M. Inagaki, Y. Hama, K. Kuniko; K. Sakaguchi, M. Iwamori, N. Okino, M. Ito:
Evidence for new b1-3 galactosyltransferase activity involved in biosynthesis of unusual N-glycan harboring T-antigen in Apis mellifera.; 2007 ANNOUNCEMENT INFO.; Biosci. Biotech. Biochem., 71, 4, 1111-1114 AUTHOR; Y. Kimura, S. Sakamura, T. Ushijima, Y. Hama, H. Kajiura, K. Fujiyama, K. Okihara, K. Hashimoto, H. Sugimoto, H. Yamada.
Antioxidant and radical scavenging activities of brown algal phlorotannins.; 2006 ANNOUNCEMENT INFO.; ITE Letters, 7, 69-72 AUTHOR; T. Shibata, K. Nagayama, S. Kawaguchi, Y.Hama
Extracellular secretion of phenolic substances from living brown algae.; 2006 ANNOUNCEMENT INFO.; J. Appl. Phycol., 18, 787-794 AUTHOR; T. Shibata, Y. Hama, T. Miyasaki, T. Nakamura
A Novel Phosphatidylcholine Which Contains Pentadecanoic Acid at sn-1 and Docosahexaenoic Acid at sn-2 in Schizochytrium sp. F26-b.; 2006 ANNOUNCEMENT INFO.; J. Biochem., 147, 247-253 AUTHOR; E. Abe, Y. Hayashi, Y. Hama, M. Hayashi, M. Inagaki, M. Ito
Structure of b-1,3-Xylooligosaccharides Generated from Caulerpa racemosa var. laete-virens b-1,3-Xylan by the Action of b-1,3-Xylanase.; 2006 ANNOUNCEMENT INFO.; J. Biochem., 140, 369-373 AUTHOR; M. Kiyohara, Y. Hama, K. Yamaguchi, M. Ito
Tumor Antigen Occurs in N-Glycan of Royal Jelly Glycoproteins: Honeybee Cells Synthesize T-antigen Unit in N-Glycan Moiety.; 2006 ANNOUNCEMENT INFO.; Biosci. Biotechnol. Bicohem, 70, 2583-2587 AUTHOR; Y. Kimura, T. Ushijima, M, Maeda, Y. Hama, M. Kimura, K. Okihara, H. Sugimoto, H. Yamada
The glycosphingolipid receptor for Vibrio trachuri in the red sea bream intestine is a GM4 ganglioside which contains 2-hydroxy fatty acids; 2005 ANNOUNCEMENT INFO.; BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 333, 2, 367-373 AUTHOR; Chisada, S. i / Horibata, Y / Hama, Y / Inagaki, M / Furuya, N / Okino, N / Ito, M
Distribution of Digestive Enzymes in the Rabbitfish Siganus fuscescens.; 2005 ANNOUNCEMENT INFO.; ITE Letters, 6, 64-67 AUTHOR; Shibata T.,Motomura J.,Yamaguchi K.,Kiriyama T.,Fujii A.,Hama Y.,Nakamura T.
Antioxidative Activity of Philippine Salt-Fermented Shrimp and Variation of Its Constituents during Fermentation; 2005 ANNOUNCEMENT INFO.; JOURNAL OF OLEO SCIENCE, 54, 10, 553-558 AUTHOR; Peralta, E. M / Hatate, H / Watanabe, D / Kawabe, D / Murata, H / Hama, Y / Tanaka, R
Purification and further characterization of a glycoprotein from the skin mucus of Japanese eels; 2004 ANNOUNCEMENT INFO.; JOURNAL OF FISH BIOLOGY, 64, 1, 100-115 AUTHOR; Sumi, T / Hama, Y / Nakagawa, H / Maruyama, D / Asakawa, M
Unique Catabolic Pathway of Glycosphingolipids in a Hydrozoan, Hydra magnipapillata, Involving Endoglycoceramidase; 2004 ANNOUNCEMENT INFO.; JOURNAL OF BIOLOGICAL CHEMISTRY, 279, 32, 33379-33389 AUTHOR; Horibata, Y / Sakaguchi, K / Okino, N / Iida, H / Inagaki, M / Fujisawa, T / Hama, Y / Ito, M
Local and chemical distribution of phlorotannins in brown algae; 2004 ANNOUNCEMENT INFO.; JOURNAL OF APPLIED PHYCOLOGY, 16, 4, 291-296 AUTHOR; Shibata, T / Kawaguchi, S / Hama, Y / Hama, Y / Inagaki, M / Yamaguchi, K / Nakamura, T
Antioxidative Activity of Lipophilic and Hydrophilic Extracts from Marine Algae.; 2004 ANNOUNCEMENT INFO.; ITE Letters, 5, 483-486 AUTHOR; Hatate H.,Murata H,, Shiomori K.,Hama Y.,Tanaka R., Suzuki N.
Interanction of GM2 Activator Protein with Glycosphingolipids.; 2003 ANNOUNCEMENT INFO.; Methods Enzymol., 363, 230-241 AUTHOR; Li S.-C.,Hama Y.,Li Y.-T.
Association of GM4 ganglioside with the membrane surrounding lipid droplets in shark liver.; 2002 ANNOUNCEMENT INFO.; J. Lipid Res., 43, 1019-1025 AUTHOR; Li Y.-T.,Sugiyama E.,Ariga T.,Nakayama J.,Hayama M.,Hama Y.,Nakagawa H.,Tai T., Maskos K., Li S.-C., Kasama T.
Structural characterization of the trisaccharide chain from the skin mucus glycoprotein of the rainbow trout, Salmo gairdneri.; 2002 ANNOUNCEMENT INFO.; Fish Physiol. Biochem., 25, 1, 11-17 AUTHOR; Sumi T.,Hama Y.,Nakagawa H.,Maruyama D.,Asakawa M.
Occurrence of GalNAcbeta1-4GlcNAc Unit in N-Glycan of Royal Jelly Glycoprotein; 2002 ANNOUNCEMENT INFO.; BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 66, 9, 1985-1989 AUTHOR; Kimura, M / Hama, Y / Tsumura, K / Okihara, K / Sugimoto, H / Yamada, H / Kimura, Y
KDN-Containing Glycoprotein from Loach Skin Mucus.; 2001 ANNOUNCEMENT INFO.; Advances in Experimental Medicine and Biology, 491, 171-184 AUTHOR; H. Nakagawa, Y. Hama, T. Sumi, S.-C. Li, and Y.-T. Li
Comparison of Protease Activity in Liver among Several Species of Squids and Cuttlefish.; 2000 ANNOUNCEMENT INFO.; Fisheries Sci., 66, 182-183 AUTHOR; H. Hatate, R. Tanaka, N. Suzuki, and Y. Hama
Stereochemical Assignment of Conjugated Carbonyls with a Prostaglandin-like Ring Structure Formed During Autoxidation of Linolenate.; 2000 ANNOUNCEMENT INFO.; J. Jpn. Oil Chem. Soc., 49, 831-837 AUTHOR; Y. Hama, T. Matsui, H. Hatate, and T. Nakamura
Quantitative Anhydrous Mercaptolysis of Algal Galactans Followed by HPLC of Component Sugars.; 1999 ANNOUNCEMENT INFO.; J. Biochem., 125, 160-165 AUTHOR; Y. Hama, H. Nakagawa, K. Mochizuki, T. Sumi, and H. Hatate
Anhydrous mercaptolysis of agar: an efficient preparation of 3,6-anhydro-L-galactose diethyl dithioacetal.; 1999 ANNOUNCEMENT INFO.; Carbohydr. Res., 318, 154-156 AUTHOR; Y. Hama, H. Nakagawa, T. Sumi, X. Xia, and K. Yamaguchi:
Coexpression of Trypsin Inhibitory and Acceleratory Substances during Autoxidation of Methyl Linolenate: Confirmation of Trypsin Inhibitory Substances.; 1999 ANNOUNCEMENT INFO.; J. Jpn. Oil Chem. Soc., 48, 917-921 AUTHOR; H. Hatate, Y. Hama, R. Tanaka, N. Suzuki, Y. Hatate, and Y. Kawano
A New Red Coloration Induced by the Reaction of Oxidized Lipids with Amino Acids.; 1998 ANNOUNCEMENT INFO.; J. Agr. Food Chem., 46, 1316-1320 AUTHOR; T. Nakamura, Y. Hama, R. Tanaka, K. Taira, and H. Hatate
A Gas Chromatographic Method for the Sugar Analysis of 3,6-Anhydrogalactose-Containing Algal Galactans.; 1998 ANNOUNCEMENT INFO.; Anal. Biochem., 265, 42-48 AUTHOR; Y. Hama, H. Nakagawa, M. Kurosawa, T. Sumi, X. Xia, and H. Hatate
Interaction of GM2 Activator Protein with Glycosphingolipids.; 1997 ANNOUNCEMENT INFO.; J. Biol. Chem., 272, 2828-2833 AUTHOR; Y. Hama, Y.-T. Li, and S.-C. Li
Enhancement of Antioxidative Activity of a-Tocopherol and Sodium Ascorbate Using Tetrapeptide Prepared from Bovine Serum Albumin Hydrolyzates.; 1997 ANNOUNCEMENT INFO.; Food Sci. Technol. Int. Tokyo, 3, 46-48 AUTHOR; H. Hatate, Y. Hama, T. Araki, and N. Suzuki
Purification and Characterization of Glycoprotein from the Skin Mucus of the Rainbow Trout, Salmo gairdceri.; 1997 ANNOUNCEMENT INFO.; Biosci. Biotech. Biochem., 61, 675-683 AUTHOR; T. Sumi, Y. Hama, D. Maruyama, M. Asakawa, and H. Nakagawa
Isolation and Properties of a Sialoglycoprotein from the Skin Mucus of the Stingray Dasyatis akajei.; 1997 ANNOUNCEMENT INFO.; Fish. Sci., 63, 453-458 AUTHOR; T. Sumi, Y. Hama, D. Maruyama, M. Asakawa, and H. Nakagawa
Structural Characterization of the Carbohydrate Chains from the Skin Mucus Sialoglycoprotein of the Stingray, Dasyatis akajei.; 1997 ANNOUNCEMENT INFO.; Fisheries Sci., 63, 779-783 AUTHOR; T. Sumi, Y. Hama, D. Maruyama, M. Asakawa, and H. Nakagawa:
Characterization of a Deaminated Neuraminic Acid-containing Glycoprotein from the Skin Mucus of the Loach, Misgrunus anguillicaudatus.; 1994 ANNOUNCEMENT INFO.; J. Biol. Chem., 269, 32138-32143 AUTHOR; M. Kimura, Y. Hama, T. Sumi, M. Asakawa, B. N. N. Rao, A. P. Hornet, S.-C. Li, Y.-T. Li, and H. Nakagawa
Conjugated Carbonyl Compounds with a Hydroxycyclopentanone Ring Formed During Autoxidation of Methyl Docosahexaenoate; 1992 ANNOUNCEMENT INFO.; J. Jpn. Oil Chem. Soc., 41, 1111-1114 AUTHOR; Y. Hama, T. Itagaki, and T. Nakamura
Conjugated Carbonyls with a Hydroxypentanone Ring in Autoxidized Methyl g-Linolenate; 1991 ANNOUNCEMENT INFO.; J. Jpn. Oil Chem. Soc, 40, 639-642 AUTHOR; Y. Hama and T. Nakamura
Determination of Conjugated Carbonyls with a Prostaglandin-like Ring Structure in Autoxidized Lipids; 1990 ANNOUNCEMENT INFO.; Nippon Suisan Gakkaishi, 56, 147-152 AUTHOR; Y. Hama, H. Maeda, and T. Nakamura
Inevitable Generation of Primary Alcohols During Reduction of Oxidized Lipids with Sodium Borohydride; 1990 ANNOUNCEMENT INFO.; Lipids, 25, 578-580 AUTHOR; T. Nakamura, H. Maeda, Y. Takahashi, and Y. Hama
Prostaglandin-like Substances, Precursors of Red Pigment, Formed during Autoxidation of Methyl Arachidonate; 1988 ANNOUNCEMENT INFO.; , 36, 15-18 AUTHOR; T. Nakamura, Y. Hama
Conjugated Carbonyls with a Prostaglandin-Like Structure Formed by Autoxidation of Eicosapentaenoate; 1988 ANNOUNCEMENT INFO.; Nippon Suisan Gakkaishi, 54, 271-275 AUTHOR; T. Nakamura, Y. Hama
Identification of a New Conjugated Carbonyl in Autoxidied Tuna Liver Oil; 1988 ANNOUNCEMENT INFO.; Nippon Suisan Gakkaishi, 54, 1669 AUTHOR; Y. Hama, T. Nakamura
General Lectures
Meiosis-independent transition from sporophyte to gametophyte in the red seaweed Pyropia yezoensis; 2018/03 ANNOUNCEMENT INFO.; AUTHOR; Koji Mikami, Chengze Li, and Yoichiro Hama
CHEMICAL ECOLOGY OF EXTRACELLULAR SECRETIONS FROM LIVING BROWN ALGAE; 2009/08 ANNOUNCEMENT INFO.; AUTHOR; Toshiyuki Shibata, Yoichiro Hama, Taiko Miyasaki, Shigeo Kawaguchi
Antioxidative Activity and Nutritional Components in Philippine: Salt-fermented shrimp paste and their variation with prolonged fermentation; 2006/11 ANNOUNCEMENT INFO.; 2006 Japan/Taiwan/korea Chemical Engineering Conference(鹿児島) AUTHOR; H. Hatate1, E. M. Peralta, H. Murata1, Y. Hama,
R. Tanaka, Y. Hatate
A novel phosphatidylcholine containing pentadecanoic acid at sn-1 and docosahexaenoic acid at sn-2 in Schizochytrium sp. F26-b; 2006/06 ANNOUNCEMENT INFO.; 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (京都) AUTHOR; E. Abe, Y. Hayashi, Y. Hama, M. Hayashi, M. Inagaki, M. Ito
Unique catabolic pathway of glycosphingolipidds in a Hydrozoan, Hydra magnipapillata, involving endoglycoceramidase.; 2004/11 ANNOUNCEMENT INFO.; US/JAPAN Glyco 2004(Honolulu, USA) AUTHOR; Y. Horibata, K. Sakaguchi, N. Okino, H. Iida, M. Inagaki, T. Fujiwara, Y. Hama M. Ito
Glycosphingolipid receptor for fish pathogen, Vibrio trachuri; 2004/11 ANNOUNCEMENT INFO.; US/JAPAN Glyco 2004(Honolulu, USA) AUTHOR; S. Chisada, Y. Horibata, M. Inagaki, Y. Hama, N. Okino, M. Ito
A fish pathogen, Vibrio trachuri, binds to GM4 ganglioside from the intesitine of red sea bream; 2004/10 ANNOUNCEMENT INFO.; AUTHOR;