Detailed Information

Themes for Ongoing Research

• Histological evaluation of atrial substrate in patients with atrial fibrillation
• Follow-up study of patients undergoing catheter ablation for atrial fibrillation: evaluation of long-term outcomes and predictive factors based on genetic predisposition

Research Topics and Results

• Histological validation of atrial structural remodelling in patients with atrial fibrillation  2023/06
• Interatrial conduction time is associated with left atrial low voltage area and predicts the recurrence after single atrial fibrillation ablation 2023/01
• Is hypertension a cause of atrial cardiomyopathy in patients with atrial fibrillation? -Evidence from atrial biopsy- 2022/10
• Hypertension is not a predictor of atrial fibrosis in patients with atrial fibrillation - evidence from atrial biopsy 2022/10
• Alcohol Consumption Is Associated With Postablation Recurrence but Not Changes in Atrial Substrate in Patients With Atrial Fibrillation: Insight from a High-Density Mapping Study  2022/07
• Atrial Structural Remodeling in Patients With Atrial Fibrillation Is a Diffuse Fibrotic Process: Evidence From High-Density Voltage Mapping and Atrial Biopsy  2022/03
• Serum Albumin and Bleeding Events After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction (from the HAGAKURE-ACS Registry)  2022/02
• Simple risk-score model for in-hospital major bleeding based on multiple blood variables in patients with acute myocardial infarction  2022/01
• Impact of Renal Dysfunction on Left Atrial Structural Remodeling and Recurrence After Catheter Ablation for Atrial Fibrillation - A Propensity Score Matching Analysis 2020/07
• Left atrial functional and structural changes associated with ablation of atrial fibrillation - Cardiac magnetic resonance study 2020/04
• Catheter ablation of atrial fibrillation reduces heart failure rehospitalization in patients with heart failure with preserved ejection fraction 2020/03
• De-HANNELING OF MRI DETECTED SCAR TO TREAT RECURRENT ARRHYTHMIAS POST-AF ABLATION 2020/02
• Late Gadolinium Enhancement Magnetic Resonance Imaging Guided Treatment of Post-Atrial Fibrillation Ablation Recurrent Arrhythmia. 2019/08
• Consider temporal aggressive rhythm control before ICD implantation in patients with heart failure with reduced ejection fraction. 2019/06
• 6. Towards Automated Quantification of Atrial Fibrosis in Images from Catheterized Fiber-Optics Confocal Microscopy Using Convolutional Neural Networks.  2019/06
• Bipolar Voltage Mapping for the Evaluation of Atrial Substrate: Can We Overcome the Challenge of Directionality?  2019/02
• Three Cases of Coil Embolization for Iatrogenic Pseudoaneurysm Following Femoral vein Puncture During Radiofrequency Catheter Ablation 2019
• De-Channeling of MRI detected scar to treat recurrent arrhythmias post-AF ablation 2019
• Comparison of Left Atrial Voltage Maps - Does Mapping Catheter Configuration Pattern Matter? 2019
• High Density Mapping Techniques in Complex Arrhythmia.  2019
• Association between local slow conduction and bipolar voltage ? an analysis using HD grid mapping catheter in atrial fibrillation patients 2019
• Does low voltage zone represent localized fibrosis? -an analysis using HD grid mapping catheter in atrial fibrillation patients  2019
• Gender differences in structural remodeling and clinical outcomes among patients undergoing atrial fibrillation ablation. 2018

Original Articles

• Histological validation of atrial structural remodelling in patients with atrial fibrillation ;　2023/06
  ANNOUNCEMENT INFO.;　Eur Heart J, ehad396
  AUTHOR;　○Takahashi Y, Yamaguchi T, Otsubo T, Nakashima K, Shinzato K, Osako R, Shichida S, Kawano Y, Fukui A, Kawaguchi A, Aishima S, Saito T, Takahashi N, Node K
  
• Interatrial conduction time is associated with left atrial low voltage area and predicts the recurrence after single atrial fibrillation ablation;　2023/01
  ANNOUNCEMENT INFO.;　J Arrhythm, 39, 2, 142-148
  AUTHOR;　*Hirota K, Fukui A, Yamaguchi T, Takahashi M, Kondo H, Akioka H, Shinohara T, Yufu K, Node K, Takahashi N
  
• Alcohol Consumption Is Associated With Postablation Recurrence but Not Changes in Atrial Substrate in Patients With Atrial Fibrillation: Insight from a High-Density Mapping Study ;　2022/07
  ANNOUNCEMENT INFO.;　J Am Heart Assoc, 11, 13, e025697
  AUTHOR;　*Sagawa Y, Nagata Y, Miwa N, Yamaguchi T, Watanabe K, Kaneko M, Nakamura T, Nozato T, Ashikaga T, Goya M, Sasano T
  
• Atrial Structural Remodeling in Patients With Atrial Fibrillation Is a Diffuse Fibrotic Process: Evidence From High-Density Voltage Mapping and Atrial Biopsy ;　2022/03
  ANNOUNCEMENT INFO.;　J Am Heart Assoc, 11, 6, e024521
  AUTHOR;　Takanori Yamaguchi, Toyokazu Otsubo, Yuya Takahashi, Kana Nakashima, Akira Fukui, Kei Hirota, Yumi Ishii, Kodai Shinzato, Ryosuke Osako, Mai Tahara, Yuki Kawano, Atsushi Kawaguchi, Shinichi Aishima, Naohiko Takahashi, Koichi Node
  
• Serum Albumin and Bleeding Events After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction (from the HAGAKURE-ACS Registry) ;　2022/02
  ANNOUNCEMENT INFO.;　Am J Cardiol, 165, 19-26
  AUTHOR;　○Goro Yoshioka, Masahiro Natsuaki, Yuhei Goriki, Kodai Shinzato, Kensaku Nishihira, Nehiro Kuriyama, Mitsuhiro Shimomura, Yohei Inoue, Toshiyuki Nishikido, Hiroshi Hongo, Tetsuya Kaneko, Kohei Kamishita, Kensuke Yokoi, Ayumu Yajima, Yoshiko Sakamoto, Motoko Tago, Atsushi Kawaguchi, Takanori Yamaguchi, Machiko Asaka, Norihiko Kotooka, Shinjo Sonoda, Yutaka Hikichi, Yoshisato Shibata, Koichi Node
  
• Simple risk-score model for in-hospital major bleeding based on multiple blood variables in patients with acute myocardial infarction ;　2022/01
  ANNOUNCEMENT INFO.;　Int J Cardiol, 346, 1-7
  AUTHOR;　○Yuhei Goriki, Goro Yoshioka, Masahiro Natsuaki, Kodai Shinzato, Kensaku Nishihira, Nehiro Kuriyama, Mitsuhiro Shimomura, Yohei Inoue, Toshiyuki Nishikido, Tetsuya Kaneko, Kensuke Yokoi, Ayumu Yajima, Yoshiko Sakamoto, Motoko Tago, Atsushi Kawaguchi, Fumi Yamamoto, Atsushi Tanaka, Takanori Yamaguchi, Aya Shiraki, Machiko Asaka, Norihiko Kotooka, Shinjo Sonoda, Yutaka Hikichi, Yoshisato Shibata, Koichi Node
  
• Impact of Renal Dysfunction on Left Atrial Structural Remodeling and Recurrence After Catheter Ablation for Atrial Fibrillation - A Propensity Score Matching Analysis;　2020/07
  ANNOUNCEMENT INFO.;　Circ J, 84, 8, 1254-1260
  AUTHOR;　*Yuya Takahashi, Takanori Yamaguchi, Akira Fukui, Toyokazu Otsubo, Kei Hirota, Yuki Kawano, Kana Nakashima, Mai Tahara, Takayuki Kitai, Atsushi Kawaguchi, Naohiko Takahashi, Koichi Node
  
• Left atrial functional and structural changes associated with ablation of atrial fibrillation - Cardiac magnetic resonance study;　2020/04
  ANNOUNCEMENT INFO.;　Int J Cardiol ., 305, 154-160
  AUTHOR;　*Ibolya Csécs, Takanori Yamaguchi, Mobin Kheirkhahan, Csilla Czimbalmos, Franziska Fochler, Eugene G Kholmovski, Alan K Morris, Gagandeep Kaur, Hajnalka Vago, Bela Merkely, Mihail G Chelu, Nassir F Marrouche, Brent D Wilson
  
• Catheter ablation of atrial fibrillation reduces heart failure rehospitalization in patients with heart failure with preserved ejection fraction;　2020/03
  ANNOUNCEMENT INFO.;　J Cardiovasc Electrophysiol, 31, 3, 682-688
  AUTHOR;　*Akira Fukui, Tomomi Tanino, Takanori Yamaguchi, Kei Hirota, Shotaro Saito, Norihiro Okada, Hidefumi Akioka, Tetsuji Shinohara, Kunio Yufu, Naohiko Takahashi
  
• Late Gadolinium Enhancement Magnetic Resonance Imaging Guided Treatment of Post-Atrial Fibrillation Ablation Recurrent Arrhythmia.;　2019/08
  ANNOUNCEMENT INFO.;　Circ Arrhythm Electrophysiol. , 12, 8, e007174
  AUTHOR;　*Fochler F, Yamaguchi T, Kheirkahan M, Kholmovski EG, Morris AK, Marrouche NF.
  
• Consider temporal aggressive rhythm control before ICD implantation in patients with heart failure with reduced ejection fraction.;　2019/06
  ANNOUNCEMENT INFO.;　Europace. , 21, 6, 835-837
  AUTHOR;　Yamaguchi T, Marrouche NF.
  
• 6. Towards Automated Quantification of Atrial Fibrosis in Images from Catheterized Fiber-Optics Confocal Microscopy Using Convolutional Neural Networks. ;　2019/06
  ANNOUNCEMENT INFO.;　Funct Imaging Model Heart. , 11504, 168-176
  AUTHOR;　*Huang C, Wasmund SL, Yamaguchi T, Knighton N, Hitchcock RW, Polejaeva IA, White KL, Marrouche NF, Sachse FB
  
• Bipolar Voltage Mapping for the Evaluation of Atrial Substrate: Can We Overcome the Challenge of Directionality? ;　2019/02
  ANNOUNCEMENT INFO.;　J Atr Fibrillation. , 11, 5, 2116
  AUTHOR;　Yamaguchi T, Fukui A, Node K.
  

Material, Commentary, Editorials, Research Report, A Comprehensive Journal Articles

• Three Cases of Coil Embolization for Iatrogenic Pseudoaneurysm Following Femoral vein Puncture During Radiofrequency Catheter Ablation;　2019
  ANNOUNCEMENT INFO.;　The Official Journal of the Japanese Society of Interventional Radiology, 33, 4, 385-389
  AUTHOR;　*Yoshitomo Kikuchi, Yunosuke Nishihara, Shinya Azama, Daisuke Okamoto, Hitoshi Aibe, Takanori Yamaguchi, Kenichi Eshima, Hiroshi Honda
  

General Lectures

• Is hypertension a cause of atrial cardiomyopathy in patients with atrial fibrillation? -Evidence from atrial biopsy-;　2022/10
  ANNOUNCEMENT INFO.;　JSH2022/ISH2022 KYOTO/APSH2022 同時開催, 2022,10,12-16
  AUTHOR;　○Yuya Takahashi, Takanori Yamaguchi, Toyokazu Otsubo, Kana Nakashima, Kodai Shinzato, Ryosuke Osako, Shigeki Shichida, Koichi Node
  
• Hypertension is not a predictor of atrial fibrosis in patients with atrial fibrillation - evidence from atrial biopsy;　2022/10
  ANNOUNCEMENT INFO.;　JSH2022/ISH2022 KYOTO/APSH2022 同時開催, 2022,10,12-16
  AUTHOR;　○Yuya Takahashi, Takanori Yamaguchi, Toyokazu Otsubo, Kana Nakashima, Kodai Shinzato, Ryosuke Osako, Shigeki Shichida, Koichi Node
  
• Comparison of Left Atrial Voltage Maps - Does Mapping Catheter Configuration Pattern Matter?;　2019
  ANNOUNCEMENT INFO.;　40th Annual Heart Rhythm Scientific Sessions, 2019, 5, 8-11
  AUTHOR;　Takanori Yamaguchi, Kana Nakashima, Toyokazu Otsubo, Yuya Takahashi, and Koichi Node
  
• Does low voltage zone represent localized fibrosis? -an analysis using HD grid mapping catheter in atrial fibrillation patients ;　2019
  ANNOUNCEMENT INFO.;　APHRS 2019-12th Asia Pacific Heart Rhythm Society Scientific Session, 2019, 10, 24-27
  AUTHOR;　Otsubo T, Yamaguchi T, Nakashima K, Tahara M, Fukui A, Hirota K, Takahashi Y, Kitai T, Takahashi N, Node K.
  
• Gender differences in structural remodeling and clinical outcomes among patients undergoing atrial fibrillation ablation.;　2018
  ANNOUNCEMENT INFO.;　APHRS 2018-11th Asia Pacific Heart Rhythm Society Scientific Session, 2018.10.17-20
  AUTHOR;　Yamaguchi T, Node K, Tsuchiya T, Otsubo T, Takahashi Y, Fukui A, Hirota K, Takahashi N, Kwano Y, Eshima K.
  

Invited Lecture, Special Lecture

• De-HANNELING OF MRI DETECTED SCAR TO TREAT RECURRENT ARRHYTHMIAS POST-AF ABLATION;　2020/02
  ANNOUNCEMENT INFO.;　13th Annual Western AF Symposium, 2020, 2, 27-28
  AUTHOR;　Yamaguchi T
  
• De-Channeling of MRI detected scar to treat recurrent arrhythmias post-AF ablation;　2019
  ANNOUNCEMENT INFO.;　12th Annual Western Atrial Fibrillation Symposium, 2019, 2, 22-23
  AUTHOR;　Takanori Yamaguchi
  
• High Density Mapping Techniques in Complex Arrhythmia. ;　2019
  ANNOUNCEMENT INFO.;　APHRS 2019-12th Asia Pacific Heart Rhythm Society Scientific Session, 2019, 10, 24-27
  AUTHOR;　Takanori Yamaguchi
  
• Association between local slow conduction and bipolar voltage ? an analysis using HD grid mapping catheter in atrial fibrillation patients;　2019
  ANNOUNCEMENT INFO.;　APHRS 2019-12th Asia Pacific Heart Rhythm Society Scientific Session, 2019, 10, 24-27
  AUTHOR;　Yamaguchi T, Otsubo T, Nakashima K Tahara M, Fukui A, Hirota K, Takahashi Y, Kitai T, Takahashi N, Node K