Detailed Information

Research Field/Keywords for Research Field

• Diagnostic pathology, Cytology, Surgical pathology, Gastroenterology, Oncology, Liver cancer, Gallbladder cancer, Translational Reserch

Education

• 2000/03, Graduated
• 2009/03, Doctor Course, Completed

Employment Experience

• 2000/05 - 2001/05
• 2001/06 - 2002/05
• 2002/06 - 2003/05
• 2003/06 - 2004/03
• 2004/04 - 2005/03 University Hospital, Faculty of Medicine, Saga University
• 2008/04 - 2009/03 Assistant Professor, University Hospital, Faculty of Medicine, Saga University
• 2009/04 - 2011/03 Assistant Professor, Medicine, Faculty of Medicine, Saga University
• 2011/04 - 2012/02 Lecturer, Medicine, Faculty of Medicine, Saga University
• 2012/03 - 2013/11 Associate Professor, Medicine, Faculty of Medicine, Saga University
• 2013/12 -  *  Associate Professor, University Hospital, Faculty of Medicine, Saga University

Field of Specialization

• Human pathology, Digestive surgery, Gastroenterology, Pathological medical chemistry

Awards

• 佐賀大学大学院医学系研究科優秀論文奨励賞 （2008/03）

Research Topics and Results

• Collision tumor of a papillary and follicular thyroid carcinoma: a case report  2023/08
• Recurrent DLBCL Developing Small Bowel Lesion of Stenotic Type, Report of a Case 2023/07
• Suppression of NASH-Related HCC by Farnesyltransferase Inhibitor through Inhibition of Inflammation and Hypoxia-Inducible Factor-1α Expression 2023/07
• スライドカンファレンス　消化器・口腔 2023/07
• Decreased placental TLR3 is associated with hepatitis B virus vaccine responsiveness in infants born to HBsAg-positive mothers 2023/06
• Diffuse Large B-cell Lymphoma Involving an Abundant Infiltration of T Follicular Helper Cells: A Case Report 2023/05
• A case report of unclassified pediatric microcystic parenchymal maldevelopment of the lung 2023/05
• Risk Factors for Postoperative Paralytic Ileus in Advanced-age Patients after Laparoscopic Colorectal Surgery: A Retrospective Study of 124 Consecutive Patients  2023/01
• Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer  2023/01
• A HIF-1α inhibitor combined with palmitic acid and L-carnitine treatment can prevent the fat metabolic reprogramming under hypoxia and induce apoptosis in hepatocellular carcinoma cells 2023
• A Case of Multicystic Biliary Hamartoma with a Marked Peribiliary Gland Component Successfully Treated by Purely Laparoscopic Anatomical Liver Resection 2023
• Laparoscopic liver resection for local recurrence after carbon‑ion radiotherapy for hepatocellular carcinoma: A case report 2023
• 【消化管リンパ増殖性疾患の診断アプローチの基本】経過中に小腸に再発病変を来した狭窄型DLBCLの1例　小腸悪性腫瘍との鑑別を中心に 2023
• 穿刺吸引細胞診で悪性を疑った好酸性細胞型濾胞腺腫の一例 2023
• 病理診断に苦慮した右腋窩副乳癌の1例 2023
• 肺内Solitary fibrous tumorのMRI所見 2023
• Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease 2022/12
• A Case of Multicystic Biliary Hamartoma with a Marked Peribiliary Gland Component Successfully Treated by Purely Laparoscopic Anatomical Liver Resection  2022/11
• A case of congenital capillary proliferation of the kidney (CCPK)  2022/06
• ALK rearrangement-associated renal cell carcinoma morphologically mimicking mucinous tubular and spindle cell carcinoma: a case report 2022/06
• Cytological Comparison between Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Image Analysis Software Using Touch Smear Samples of Surgically Resected Specimens  2022/05
• A case of pulmonary mucosa-associated lymphoid tissue lymphoma transforming into diffuse large B-cell lymphoma 2022/01
• Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression 2021/12
• Fatal fat embolism syndrome during posterior spinal fusion surgery: A case report and literature review 2021/12
• Intracranial Mönckeberg's Atherosclerosis Is Frequently Found in Autopsy Cases of Advanced Stage Malignancy with Cerebral Infarction 2021/10
• Infiltration of CD1a-positive dendritic cells in advanced laryngeal cancer correlates with unfavorable outcomes post-laryngectomy  2021/08
• Recognition and pathological features of periampullary region adenocarcinoma with an indeterminable origin  2021/06
• Modification of the Thermal Spread by the Blade Shape of an Ultrasonically Activated Device  2021/06
• A deep learning model to detect pancreatic ductal adenocarcinoma on endoscopic ultrasound-guided fine-needle biopsy  2021/04
• Immunohistochemical analysis of the aggregation of CD1a-positive dendritic cells in resected specimens and its association with surgical outcomes for patients with gallbladder cancer 2021/01
• Cytological Appearances of Ovarian Seromucinous Borderline Tumor in Ascites: Presentation of 2 Cases 2021
• Accumulation of Astrocytic Aquaporin 4 and Aquaporin 1 in Prion Protein Plaques 2020/04
• The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients 2020/04
• Decreased cytokeratin 7 expression correlates with the progression of cervical squamous cell carcinoma and poor patient outcomes. 2019/11
• Frequent Detection of Pituitary-Derived PrPres in Human Prion Diseases. 2019/10
• Development and Validation of a Nomogram for Early Detection of Malignant Gallbladder Lesions. 2019/10
• Primary mucoepidermoid carcinoma of the liver with CRTC1-MAML2 fusion: a case report. 2019/07
• Primary Chest Wall MYC/BCL6 Double-hit Lymphoma with t (3;7) (q27;p12) and t (8;14) (q24;q32) Translocations. 2019/07
• Transferrin receptor 1 overexpression is associated with tumour de-differentiation and acts as a potential prognostic indicator of hepatocellular carcinoma. 2019/07
• Locally distributed multicentric plasmacytomas in the ileum secondary to lymphoma chemoimmunotherapy. 2019/06
• The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients. 2019/05
• Predictive value of the ratio of 8?hydroxydeoxyguanosine levels between cancerous and normal tissues in patients with stage II/III colorectal cancer. 2019/05
• Oral ulceration: an unusual manifestation of lymphomatoid granulomatosis. 2019/05
• Formalin fixation on HER-2 and PD-L1 expression in gastric cancer: A pilot analysis using the same surgical specimens with different fixation times. 2019/02
• Correlation between smoking habit and surgical outcomes on viral-associated hepatocellular carcinomas. 2018
• High-dose Factor XIII administration induces effective hemostasis for trauma-associated coagulopathy (TAC) both in vitro and in rat hemorrhagic shock in vivo models. 2018
• Occult HBV infection status and its impact on surgical outcomes in patients with curative resection for HCV-associated hepatocellular carcinoma. 2018
• Clear Cell Carcinoma of the Uterine Cervix Presented as a Submucosal Tumor Arising in a Background of Cervical Endometriosis. 2018
• A dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like features. 2018
• Synchronous mantle cell lymphoma and lung adenocarcinoma presenting in a pleural effusion: A rare tumour combination and a potential pitfall of cytodiagnosis. 2018
• Gastric adenocarcinoma of fundic gland type with signet-ring cell carcinoma component: A case report and review of the literature. 2018
• Primary Pulmonary Colloid Adenocarcinoma: How Can We Obtain a Precise Diagnosis? 2018
• A Rare Case of Kikuchi-Fujimoto Disease With Diffuse Lung Involvement Presenting a Lymphatic-like Distribution on Thin-section Computed Tomography. 2018
• Didactic surgical experience of thyroid metastasis from renal cell carcinoma: A case report. 2018
• A case of osimertinib-resistant lung adenocarcinoma responded effectively to alternating therapy. 2018
• Current smoking habit is a risk factor for poor surgical outcome of non-B, non-C hepatocellular carcinoma 2018
• Inverse correlation between CD8+ inflammatory cells and E-cadherin expression in gallbladder cancer: Tissue microarray and imaging analysis. 2017
• Impact of smoking habit on surgical outcomes in non-B non-C patients with curative resection for hepatocellular carcinoma. 2017
• Difficulty in the Cytodiagnosis of Mammary Analogue Secretory Carcinoma: Survey of 109 Cytologists with a Case Originating from a Minor Salivary Gland. 2017
• Haptoglobin Reduces Inflammatory Cytokine INF-γ and Facilitates Clot Formation in Acute Severe Burn Rat Model. 2017
• Occult hepatitis B virus infection and surgical outcomes in non-B, non-C patients with curative resection for hepatocellular carcinoma. 2017
• Autopsy case of systemic EBV-positive T-cell lymphoma of childhood with marked hepatomegaly in a middle-aged man. 2017
• Colonic poorly differentiated adenocarcinoma with abundant cancer-associated fibroblasts diagnosed by trans-gastric endoscopic ultrasound-guided fine needle aspiration cytology. 2017
• A Case of Signet Ring Cell Carcinoma of the Gallbladder Which Was Treated by Aggressive Surgery and Intensive Adjuvant Chemotherapy. 2017
• Nasal hemophilic pseudotumor in a patient with mild hemophilia A and allergic rhinitis. 2017
• Paraneoplastic Sarcoidosis in Multiple Myeloma. 2017
• Cytokeratin immunohistochemistry improves interobserver variability between unskilled pathologists in the evaluation of tumor budding in T1 colorectal cancer. 2016
• Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer. 2016
• Palsy of the recurrent laryngeal nerves in association with an ultrasonic activated device during thoracoscopic esophagectomy with three-field lymphadenectomy. 2016
• Organ-specific concept and controversy for premalignant lesions and carcinogenesis of gallbladder cancer. 2016
• Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report. 2016
• Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma with Cardiac Metastasis and Arterial Tumor Embolisms during First-Course Chemotherapy. 2016
• Cytological difference of nuclei between hepatocellular carcinoma and cholangiocellular carcinoma 2016
• A Case of Radical Resection for Small Cell Carcinoma of the Bile Duct 2015/09
• New molecular staging with G-factor supplements TNM classification in gastric cancer: a multicenter collaborative research by the Japan Society for Gastroenterological Carcinogenesis G-Project committee. 2015
• The value of trefoil factor 3 expression in predicting the long‑term outcome and early recurrence of colorectal cancer. 2015
• Granulomatous reaction in hepatic inflammatory angiomyolipoma after chemoembolization and spontaneous rupture. 2015
• A case of mucosa-associated lymphoid tissue lymphoma of the gastrointestinal tract showing extensive plasma cell differentiation with prominent Russell bodies. 2014
• Gallbladder cancer: Clinical and pathological approach.  2014
• Curative resection of gallbladder cancer with liver invasion and hepatic metastasis after chemotherapy with gemcitabine plus S-1: report of a case. 2014
• HIF-1αis a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer. 2014
• Usual and unusual gross appearance of hepatocellular carcinomas 2012
• Analysis of Extrahepatic Multiple Primary Malignancies in Patients with Hepatocellular Carcinoma according to Viral Infection Status. 2012
• Metachronous aortic aneurysms due to sarcoidosis. 2012
• Hepatoid carcinoma of the pancreas penetrating into the gastric cavity: A case report and literature review 2012
• A case of unclassified multicystic biliary tumor with biliary adenofibroma features 2012
• A unique case of gallbladder cancer arising in the neck side of segmental adenomyomatosis that mimicked hepatocellular carcinoma on contrast CT 2012
• Clinicopathologic features of advanced gallbladder cancer associated with adenomyomatosis. 2011/12
• Tumor budding and dedifferentiation in gallbladder carcinoma: potential for the prognostic factors in T2 lesions. 2011/10
• Fibroadenoma of the gallbladder with borderline malignancy: a poorly recognized gallbladder tumor. 2009/12
• Hypoxia-inducible factor-1alpha expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer. 2009/10
• Active neovascularization and possible vascular-centric development of gastric and periscapular elastofibromas 2009/02
• A long-time survivor of alpha-fetoprotein-producing gastric cancer successfully treated by fluoropyrimidine-based chemotherapy: a case study 2009
• Intrahepatic multicystic biliary hamartoma: report of a case. 2008/06
• Protein ratio of OPRT/TS or OPRT/(TS+DPD) evaluated by quantiative double fluorescence immunohistochemistry is a useful tool to predict drug efficacy of S-1 for gastric cancer. 2008/04
• An autopsy case of obstructive jaundice due to hepatic multiple peribiliary cysts accompanying hepatolithiasis 2008/02
• Quantitative double fluorescence immunohistochemistry (qDFIHC), a novel technology to assess protein expression: A pilot study analyzing 5-FU sensitive markers thymidylate synthase, dihydoropyrimidine dehydrogenase, and orotate phosphoribosyl transferase in gastric cancer tissue specimens. 2007/12

Books

• Recurrent DLBCL Developing Small Bowel Lesion of Stenotic Type, Report of a Case;　2023/07
  ANNOUNCEMENT INFO.;　Stomach and Intestine, 58, 7, 929-935
  AUTHOR;　○Motohiro Esaki, Takashi Akutagawa, Ryo Shimoda, Takahiro Yukimoto, Takuya Shimamura, Hidekazu Itamura, Yukie Yoda, Keita Kai, Keisuke Kawasaki, Shinya Kimura, Hirokazu Noshiro
  
• A case of mucosa-associated lymphoid tissue lymphoma of the gastrointestinal tract showing extensive plasma cell differentiation with prominent Russell bodies.;　2014
  ANNOUNCEMENT INFO.;　World Clinical Case Report. , 1665-1669
  AUTHOR;　○Kai K, Miyahara M, Tokuda Y, Kido S, Masuda M, Takase Y, Tokunaga O.
  
• Usual and unusual gross appearance of hepatocellular carcinomas;　2012
  ANNOUNCEMENT INFO.;　Hepatocellular Carcinoma: Clinical Research. by Lau J.W.Y., INTEC, 155-180
  AUTHOR;　Kai K, Miyoshi A, Kitahara K, Miyazaki K, Noshiro H, Tokunaga O
  

Original Articles

• Suppression of NASH-Related HCC by Farnesyltransferase Inhibitor through Inhibition of Inflammation and Hypoxia-Inducible Factor-1α Expression;　2023/07
  ANNOUNCEMENT INFO.;　Int J Mol Sci, 24, 14, 11546
  AUTHOR;　○Yamada K, Tanaka T, Kai K, Matsufuji S, Ito K, Kitajima Y, Manabe T, Noshiro H
  
• Decreased placental TLR3 is associated with hepatitis B virus vaccine responsiveness in infants born to HBsAg-positive mothers;　2023/06
  ANNOUNCEMENT INFO.;　Transl Pediatr, 12, 6, 1204-1212
  AUTHOR;　*Wu L, Fu G, Xu X, Yi L, Yao T, Wan H, Li J, Wang B, Feng S, Feng Y, Wang H, Tacke F, Kwok R, Kai K, Wang S
  
• Diffuse Large B-cell Lymphoma Involving an Abundant Infiltration of T Follicular Helper Cells: A Case Report;　2023/05
  ANNOUNCEMENT INFO.;　Intern Med, 62, 9, 1335-1340
  AUTHOR;　○Keitaro Ishii, Kazuharu Kamachi, Sho Okamoto, Hiroo Katsuya, Mai Fujita, Toshiaki Nagaie, Atsujiro Nishioka, Mariko Yoshimura, Hiroshi Ureshino, Yasushi Kubota, Toshihiko Ando, Tatsuro Watanabe, Mai Takeuchi, Keita Kai, Koichi Ohshima, Shinya Kimura
  
• Risk Factors for Postoperative Paralytic Ileus in Advanced-age Patients after Laparoscopic Colorectal Surgery: A Retrospective Study of 124 Consecutive Patients ;　2023/01
  ANNOUNCEMENT INFO.;　J Anus Rectum Colon, 7, 1, 30-37
  AUTHOR;　*Fujimoto T, Manabe T, Yukimoto K, Tsuru Y, Kitagawa H, Okuyama K, Takesue S, Kai K, Noshiro H
  
• Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer ;　2023/01
  ANNOUNCEMENT INFO.;　BMC Cancer, 23, 1, 77
  AUTHOR;　○Harada Y, Sato A, Nakamura H, Kai K, Kitamura S, Nakamura T, Kurihara Y, Ikeda S, Sueoka E, Kimura S, Sueoka-Aragane N
  
• A HIF-1α inhibitor combined with palmitic acid and L-carnitine treatment can prevent the fat metabolic reprogramming under hypoxia and induce apoptosis in hepatocellular carcinoma cells;　2023
  ANNOUNCEMENT INFO.;　, 8, 11, 25
  AUTHOR;　〇Matsufuji S, Kitajima Y, Higure K, Kimura N, Maeda S, Yamada K, Ito K, Tanaka T, Kai K, Noshiro H.
  
• Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease;　2022/12
  ANNOUNCEMENT INFO.;　J Neuropathol Exp Neurol, 82, 1, 38-48
  AUTHOR;　*Noguchi H, Koyama S, Yagita K, Shijo M, Matsuzono K, Hamasaki H, Kanemaru T, Okamoto T, Kai K, Aishima S, Abe K, Sasagasako N, Honda H
  
• A Case of Multicystic Biliary Hamartoma with a Marked Peribiliary Gland Component Successfully Treated by Purely Laparoscopic Anatomical Liver Resection ;　2022/11
  ANNOUNCEMENT INFO.;　J Gastrointest Cancer
  AUTHOR;　Kai K, Ide T, Tanaka T, Yukimoto K, Irie H, Noshiro H, Aishima S
  
• Cytological Comparison between Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Image Analysis Software Using Touch Smear Samples of Surgically Resected Specimens ;　2022/05
  ANNOUNCEMENT INFO.;　Cancers (Basel), 14, 9, 2301
  AUTHOR;　○Sho Kitamura, Keita Kai, Mitsuo Nakamura, Tomokazu Tanaka, Takao Ide, Hirokazu Noshiro, Eisaburo Sueoka, Shinich Aishima
  
• Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression;　2021/12
  ANNOUNCEMENT INFO.;　Int J Oncol, 59, 6, 102
  AUTHOR;　○Kotaro Ito, Yoshihiko Kitajima, Keita Kai, Shohei Matsufuji, Kohei Yamada, Noriyuki Egawa, Hiroshi Kitagawa, Keiichiro Okuyama, Tomokazu Tanaka, Hirokazu Noshiro
  
• Intracranial Mönckeberg's Atherosclerosis Is Frequently Found in Autopsy Cases of Advanced Stage Malignancy with Cerebral Infarction;　2021/10
  ANNOUNCEMENT INFO.;　Cancers (Basel), 13, 20, 5234
  AUTHOR;　Chika Shichijo, Keita Kai, Kazuki Jinnouchi, Masashi Nishihara, Hideo Hara, Shinichi Aishima
  
• Infiltration of CD1a-positive dendritic cells in advanced laryngeal cancer correlates with unfavorable outcomes post-laryngectomy ;　2021/08
  ANNOUNCEMENT INFO.;　BMC Cancer, 21, 1, 973
  AUTHOR;　Akimichi Minesaki, Keita Kai, Yuichiro Kuratomi, Shinichi Aishima
  
• Recognition and pathological features of periampullary region adenocarcinoma with an indeterminable origin ;　2021/06
  ANNOUNCEMENT INFO.;　Cancer Med, 10, 11, 3499-3510
  AUTHOR;　*Ryuji Komine, Motohiro Kojima, Genichiro Ishi, Masashi Kudo, Motokazu Sugimoto, Shin Kobayashi, Shinichiro Takahashi, Masaru Konishi, Tatsushi Kobayashi, Tetsuo Akimoto, Ayumi Murakami, Motoko Sasaki, Mariko Tanaka, Akiko Matsuzaki, Nobuyuki Ohike, Katsunori Uchida, Tomoko Sugiyama, Kenichi Hirabayashi, Takuma Tajiri, Kazuyuki Ishida, Keita Kai, Yuko Omori, Kenji Notohara, Hiroshi Yamaguchi, Yoko Matsuda, Yoshiki Naito, Yuki Fukumura, Yoshihiro Hamada, Yumi Mihara, Yohei Masugi, Naoto Gotohda, Kenichi Harada, Noriyoshi Fukushima, Toru Furukawa
  
• Modification of the Thermal Spread by the Blade Shape of an Ultrasonically Activated Device ;　2021/06
  ANNOUNCEMENT INFO.;　World J Surg, 45, 6, 1698-1705
  AUTHOR;　*Shuhei Kajiwara, Hirokazu Noshiro, Hiroshi Kitagawa, Tomokazu Tanaka, Keita Kai
  
• A deep learning model to detect pancreatic ductal adenocarcinoma on endoscopic ultrasound-guided fine-needle biopsy ;　2021/04
  ANNOUNCEMENT INFO.;　Sci Rep, 11, 1, 8454
  AUTHOR;　*Yoshiki Naito, Masayuki Tsuneki, Noriyoshi Fukushima, Yutaka Koga, Michiyo Higashi, Kenji Notohara, Shinichi Aishima, Nobuyuki Ohike, Takuma Tajiri, Hiroshi Yamaguchi, Yuki Fukumura, Motohiro Kojima, Kenichi Hirabayashi, Yoshihiro Hamada, Tomoko Norose, Keita Kai, Yuko Omori, Aoi Sukeda, Hirotsugu Noguchi, Kaori Uchino, Junya Itakura, Yoshinobu Okabe, Yuichi Yamada, Jun Akiba, Fahdi Kanavati, Yoshinao Oda, Toru Furukawa, Hirohisa Yano
  
• Immunohistochemical analysis of the aggregation of CD1a-positive dendritic cells in resected specimens and its association with surgical outcomes for patients with gallbladder cancer;　2021/01
  ANNOUNCEMENT INFO.;　Transl Oncol, 14, 1, 100923
  AUTHOR;　Keita Kai, Tomokazu Tanaka, Takao Ide, Atsushi Kawaguchi, Hirokazu Noshiro, Shinichi Aishima
  
• Accumulation of Astrocytic Aquaporin 4 and Aquaporin 1 in Prion Protein Plaques;　2020/04
  ANNOUNCEMENT INFO.;　J Neuropathol Exp Neurol, 79, 4, 419-429
  AUTHOR;　*Shoko Sadashima, Hiroyuki Honda, Satoshi O Suzuki, Masahiro Shijo, Shinichi Aishima, Keita Kai, Junichi Kira, Toru Iwaki
  
• The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients;　2020/04
  ANNOUNCEMENT INFO.;　Rheumatology (Oxford), 59, 4, 918
  AUTHOR;　○Nobuyuki Ono, Keita Kai, Akihito Maruyama, Mariko Sakai, Yuri Sadanaga, Shuichi Koarada, Takuya Inoue, Yoshifumi Tada
  
• Decreased cytokeratin 7 expression correlates with the progression of cervical squamous cell carcinoma and poor patient outcomes.;　2019/11
  ANNOUNCEMENT INFO.;　J Obstet Gynaecol Res., 45, 11, 2228-2236
  AUTHOR;　Hashiguchi M, Masuda M, Kai K, Nakao Y, Kawaguchi A, Yokoyama M, Aishima S.
  
• Frequent Detection of Pituitary-Derived PrPres in Human Prion Diseases.;　2019/10
  ANNOUNCEMENT INFO.;　J Neuropathol Exp Neurol., 78, 10, 922-929
  AUTHOR;　*Honda H, Matsumoto M, Shijo M, Hamasaki H, Sadashima S, Suzuki SO, Aishima S, Kai K, Nakayama KI, Sasagasako N, Iwaki T.
  
• Development and Validation of a Nomogram for Early Detection of Malignant Gallbladder Lesions.;　2019/10
  ANNOUNCEMENT INFO.;　Clin Transl Gastroenterol., 10, 10, e00098
  AUTHOR;　*Chen M, Cao J, Bai Y, Tong C, Lin J, Jindal V, Barchi LC, Nadalin S, Yang SX, Pesce A, Panaro F, Ariche A, Kai K, Memeo R, Bekaii-Saab T, Cai X
  
• Transferrin receptor 1 overexpression is associated with tumour de-differentiation and acts as a potential prognostic indicator of hepatocellular carcinoma.;　2019/07
  ANNOUNCEMENT INFO.;　Histopathology., 75, 1, 63-73
  AUTHOR;　Adachi M, Kai K, Yamaji K, Ide T, Noshiro H, Kawaguchi A, Aishima S.
  
• The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients.;　2019/05
  ANNOUNCEMENT INFO.;　Rheumatology (Oxford). , 58, 5, 786-791
  AUTHOR;　○Ono N, Kai K, Maruyama A, Sakai M, Sadanaga Y, Koarada S, Inoue T, Tada Y.
  
• Predictive value of the ratio of 8?hydroxydeoxyguanosine levels between cancerous and normal tissues in patients with stage II/III colorectal cancer.;　2019/05
  ANNOUNCEMENT INFO.;　Oncol Rep., 41, 5, 3041-3050
  AUTHOR;　○Kitagawa H, Kitajima Y, Kai K, Komukai S, Tanaka T, Koga Y, Manabe T, Noshiro H.
  
• Formalin fixation on HER-2 and PD-L1 expression in gastric cancer: A pilot analysis using the same surgical specimens with different fixation times.;　2019/02
  ANNOUNCEMENT INFO.;　World J Clin Cases., 7, 4, 419-430
  AUTHOR;　Kai K, Yoda Y, Kawaguchi A, Minesaki A, Iwasaki H, Aishima S, Noshiro H.
  
• Correlation between smoking habit and surgical outcomes on viral-associated hepatocellular carcinomas.;　2018
  ANNOUNCEMENT INFO.;　World J Gastroenterol. , 24, 1, 58-68
  AUTHOR;　Kai K, Komukai S, Koga H, Yamaji K, Ide T, Kawaguchi A, Aishima S, Noshiro H.
  
• High-dose Factor XIII administration induces effective hemostasis for trauma-associated coagulopathy (TAC) both in vitro and in rat hemorrhagic shock in vivo models.;　2018
  ANNOUNCEMENT INFO.;　J Trauma Acute Care Surg. , 85, 3, 588-597
  AUTHOR;　○Nagashima F, Inoue S, Koami H, Miike T, Sakamoto Y, Kai K.
  
• Occult HBV infection status and its impact on surgical outcomes in patients with curative resection for HCV-associated hepatocellular carcinoma.;　2018
  ANNOUNCEMENT INFO.;　Hepatobiliary Surg Nutr. , 7, 6, 443-453
  AUTHOR;　Yamaji K, Kai K, Komukai S, Koga H, Ide T, Kawaguchi A, Noshiro H, Aishima S.
  
• Inverse correlation between CD8+ inflammatory cells and E-cadherin expression in gallbladder cancer: Tissue microarray and imaging analysis.;　2017
  ANNOUNCEMENT INFO.;　World J Clin Cases. , 5, 1, 1-8.
  AUTHOR;　Kai K, Masuda M, Aishima S.
  
• Impact of smoking habit on surgical outcomes in non-B non-C patients with curative resection for hepatocellular carcinoma.;　2017
  ANNOUNCEMENT INFO.;　World J Gastroenterol. , 23, 8, 1397-1405
  AUTHOR;　Kai K, Koga H, Aishima S, Kawaguchi A, Yamaji K, Ide T, Ueda J, Noshiro H.
  
• Difficulty in the Cytodiagnosis of Mammary Analogue Secretory Carcinoma: Survey of 109 Cytologists with a Case Originating from a Minor Salivary Gland.;　2017
  ANNOUNCEMENT INFO.;　Acta Cytol. , 61, 6, 469-476
  AUTHOR;　Kai K, Minesaki A, Suzuki K, Monji M, Nakamura M, Tsugitomi H, Kuratomi Y, Aishima S
  
• Haptoglobin Reduces Inflammatory Cytokine INF-γ and Facilitates Clot Formation in Acute Severe Burn Rat Model.;　2017
  ANNOUNCEMENT INFO.;　Nippon Med Sch. , 84, 2, 64-72
  AUTHOR;　〇Koami H, Sakamoto Y, Miyasho T, Noguchi R, Sato N, Kai K, Chris Yamada K, Inoue S.
  
• Occult hepatitis B virus infection and surgical outcomes in non-B, non-C patients with curative resection for hepatocellular carcinoma.;　2017
  ANNOUNCEMENT INFO.;　World J Hepatol. , 9, 35, 1286-1295
  AUTHOR;　Koga H, Kai K, Aishima S, Kawaguchi A, Yamaji K, Ide T, Ueda J, Noshiro H.
  
• Cytokeratin immunohistochemistry improves interobserver variability between unskilled pathologists in the evaluation of tumor budding in T1 colorectal cancer.;　2016
  ANNOUNCEMENT INFO.;　Pathol Int., 66, 2, 75-82
  AUTHOR;　Kai K, Aishima S, Aoki S, Takase Y, Uchihashi K, Masuda M, Nishijima-Matsunobu A, Yamamoto M, Ide K, Nakayama A, Yamasaki M, Toda S.
  
• Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer.;　2016
  ANNOUNCEMENT INFO.;　Oncol Lett., 11, 2, 1026-1034
  AUTHOR;　〇Kubo H, Kitajima Y, Kai K, Nakamura J, Miyake S, Yanagihara K, Morito K, Tanaka T, Shida M, Noshiro H.
  
• Palsy of the recurrent laryngeal nerves in association with an ultrasonic activated device during thoracoscopic esophagectomy with three-field lymphadenectomy.;　2016
  ANNOUNCEMENT INFO.;　Esophagus, 13, 4, 351–360
  AUTHOR;　〇Noshiro H, Kai K, Yoda Y, Kono H, Uchiyama A
  
• New molecular staging with G-factor supplements TNM classification in gastric cancer: a multicenter collaborative research by the Japan Society for Gastroenterological Carcinogenesis G-Project committee.;　2015
  ANNOUNCEMENT INFO.;　Gastric Cancer., 18, 1, 119-28
  AUTHOR;　*Sawada T, Yashiro M, , Miyazaki K, Kai K, et al.
  
• The value of trefoil factor 3 expression in predicting the long‑term outcome and early recurrence of colorectal cancer.;　2015
  ANNOUNCEMENT INFO.;　Int J Oncol., 46, 2, 563-8
  AUTHOR;　○Morito K, Nakamura J, Kitajima Y, Kai K, Tanaka T, Kubo H, Miyake S, Noshiro H.
  
• Analysis of Extrahepatic Multiple Primary Malignancies in Patients with Hepatocellular Carcinoma according to Viral Infection Status.;　2012
  ANNOUNCEMENT INFO.;　Int J Hepatol., 2012, 495950
  AUTHOR;　Kai K, Miyoshi A, Kitahara K, Masuda M, Takase Y, Miyazaki K, Noshiro H, Tokunaga O.
  
• Clinicopathologic features of advanced gallbladder cancer associated with adenomyomatosis.;　2011/12
  ANNOUNCEMENT INFO.;　Virchows Arch. 2011;　, 459, 6, 573-580
  AUTHOR;　Kai K, Ide T, Masuda M, Kitahara K, Miyoshi A, Miyazaki K, Noshiro H, Tokunaga O.
  
• Tumor budding and dedifferentiation in gallbladder carcinoma: potential for the prognostic factors in T2 lesions.;　2011/10
  ANNOUNCEMENT INFO.;　Virchows Arch. 2011;　, 459, 4, 449-456
  AUTHOR;　Kai K, Kohya N, Kitahara K, Masuda M, Miyoshi A, Ide T, Tokunaga O, Miyazaki K, Noshiro H.
  
• Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer.;　2011/02
  ANNOUNCEMENT INFO.;　Am J Pathol. 2011;　, 178, 2, 515-524
  AUTHOR;　Nakamura J, Kitajima Y, Kai K, Hashiguchi K, Hiraki M, Noshiro H, Miyazaki K.
  
• A complete response in small cell carcinoma of the esophagus treated by S-1/Cisplatin combined chemotherapy and radiotherapy;　2010/12
  ANNOUNCEMENT INFO.;　J Gastrointest Cancer, 41, 275-280
  AUTHOR;　Hiraki M, Tanaka M, Sato S, Kai K, Morito K, Kobayashi K, Noshiro H, Tokunaga O, Miyazaki K
  
• Endoglin (CD105) expression and angiogenesis status in small cell lung cancer;　2010/11
  ANNOUNCEMENT INFO.;　Pathology – Research and Practice, 206, 725-730
  AUTHOR;　Takase Y, Kai K, Masuda M, Akashi M, Tokunaga O
  
• Ribonucleotide reductase subunit M1 assessed by quantitative double-fluorescence immunohistochemistry predicts the efficacy of gemcitabin in biliary tract carcinoma;　2010/10
  ANNOUNCEMENT INFO.;　Int J of Oncology, 37, 845-852
  AUTHOR;　Nakamura J, Kohya N, Kai K, Ohtaka K, Hashiguchi K, Hiraki M, Kitajima Y, Tokunaga O, Noshiro H, Miyazaki K
  
• Gallbladder carcinoma with a large monolocular cystic cancerous component;　2010/09
  ANNOUNCEMENT INFO.;　Oncology Letters, 1, 995-998
  AUTHOR;　Hiraki M, Yakushiji H, Hashiguchi K, Harada S, Kohya N, Kai K, Yamaguchi K, Mori D, Irie K, Tokunaga O, Noshiro H, Miyazaki K
  
• Immunohistochemical and molecular genetic analyses of multiple sporadic gastrointestinal stromal tumors;　2010/09
  ANNOUNCEMENT INFO.;　World J Gastrointest Oncol., 2, 364-368
  AUTHOR;　Hiraki M, Kitajima Y, Ohtsuka T, Kai K, Miyake S, Koga Y, Mori D, Noshiro H, Tokunaga O, Miyazaki K.
  
• HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy;　2010/09
  ANNOUNCEMENT INFO.;　Int J Cancer., 127, 1158-1171
  AUTHOR;　Nakamura J, Kitajima Y, Kai K, Hashiguchi K, Hiraki M, Noshiro H, Miyazaki K.
  
• A quantitative evaluation of the determinant proteins for S-1 responsiveness in a biopsy specimen assists in patient selection to neoadjuvant therapy in cases of advanced gastric cancer;　2010/08
  ANNOUNCEMENT INFO.;　Int J of Oncology, 37, 257-264
  AUTHOR;　Hashiguchi K, Kitajima Y, Kai K, Hiraki M, Nakamura J, Tokunaga O, Noshiro H, Miyazaki K
  
• A hepatocellular neoplasm accompanied with massive histiocyte infiltration;　2010/03
  ANNOUNCEMENT INFO.;　Clin J Gastroenterol, 3, 40-44
  AUTHOR;　Kai K, Miyoshi A, Tokunaga O, Kitahara K, Takahashi T, Miyake S, Egashira Y, Irie H, Noshiro H, Miyazaki K
  
• Tranilast strongly sensitizes pancreatic cancer cells to gemcitabine via decreasing protein expression of ribonucleotide reductase 1;　2010/02
  ANNOUNCEMENT INFO.;　Int J Oncol., 36, 341-349
  AUTHOR;　Mitsuno M, Kitajima Y, Ohtaka K, Kai K, Hashiguchi K, Nakamura J, Hiraki M, Noshiro H, Miyazaki K
  
• Fibroadenoma of the gallbladder with borderline malignancy: a poorly recognized gallbladder tumor.;　2009/12
  ANNOUNCEMENT INFO.;　J Hepatobiliary Pancreat Surg., 16, 6, 874-877
  AUTHOR;　Magata S, Kai K, Mori M, Edakuni G, Tokunaga O, Miyazaki K.
  
• Hypoxia-inducible factor-1alpha expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer.;　2009/10
  ANNOUNCEMENT INFO.;　Oncol Rep., 22, 4, 693-699
  AUTHOR;　Nakamura J, Kitajima Y, Kai K, Mitsuno M, Ide T, Hashiguchi K, Hiraki M, Miyazaki K.
  
• Fumagillin inhibits colorectal cancer growth and metastasis in mice: in vivo and in vitro study of anti-angiogenesis.;　2009/07
  ANNOUNCEMENT INFO.;　Pathol Int., 59, 7, 448-461
  AUTHOR;　Hou L, Mori D, Takase Y, Meihua P, Kai K, Tokunaga O.
  
• Anti-CD105 Inhibits Primary Cancer Growth and Secondary Hematogenous Metastasis in a Xenograft Model;　2009/06
  ANNOUNCEMENT INFO.;　, 6, 91-96
  AUTHOR;　Minhajat R, Hou L, Kai K, Takase Y, Mori D, Tokunaga O.
  
• Active neovascularization and possible vascular-centric development of gastric and periscapular elastofibromas;　2009/02
  ANNOUNCEMENT INFO.;　Virchows Arch., 454, 2, 181-188
  AUTHOR;　Kai K, Kusano K, Sakai M, Tabuchi M, Yunotani S, Miyazaki K, Tokunaga O.
  
• A long-time survivor of alpha-fetoprotein-producing gastric cancer successfully treated by fluoropyrimidine-based chemotherapy: a case study;　2009
  ANNOUNCEMENT INFO.;　Clin J Gastroenterol., 2, 331-337
  AUTHOR;　Hiraki M, Sato S, Kai K, Ohtsuka T, Kohya N, Kitajima Y, Nakafusa Y, Tokunaga O, Miyazaki K.
  
• Hypoxia-inducible factor-1alpha expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer.;　2009
  ANNOUNCEMENT INFO.;　Oncol Rep. 22:693-699., 22, 693-699
  AUTHOR;　○Nakamura J, Kitajima Y, Kai K, Mitsuno M, Ide T, Hashiguchi K, Hiraki M, Miyazaki K.
  
• Intrahepatic multicystic biliary hamartoma: report of a case.;　2008/06
  ANNOUNCEMENT INFO.;　Hepatology Research, 38, 629-634
  AUTHOR;　Kai K, Takahashi T, Miyoshi A, Yasui T, Tokunaga O, Miyazaki K.
  
• An autopsy case of obstructive jaundice due to hepatic multiple peribiliary cysts accompanying hepatolithiasis;　2008/02
  ANNOUNCEMENT INFO.;　Hepatology Research, 38, 211-216
  AUTHOR;　Kai K, Eguchi Y, Kumagai T, Sugita Y, Tokunaga O
  
• Quantitative double fluorescence immunohistochemistry (qDFIHC), a novel technology to assess protein expression: A pilot study analyzing 5-FU sensitive markers thymidylate synthase, dihydoropyrimidine dehydrogenase, and orotate phosphoribosyl transferase in gastric cancer tissue specimens.;　2007/12
  ANNOUNCEMENT INFO.;　Cancer Lett., 258, 1, 45-54
  AUTHOR;　Kai K, Kitajima Y, Hiraki M, Satoh S, Tanaka M, Nakafusa Y, Tokunaga O, Miyazaki K.
  
• Multiple inflammatory pseudotumor of the liver, mimicking cholangiocarcinoma with tumor embolus in the hepatic vein: report of a case.;　2007/06
  ANNOUNCEMENT INFO.;　Surg Today., 37, 6, 530-533
  AUTHOR;　Kai K, Matsuyama S, Ohtsuka T, Kitahara K, Mori D, Miyazaki K.
  
• Ethanol injection for ablation of an intractable digestive tract fistula: report of a case.;　2006/08
  ANNOUNCEMENT INFO.;　Surg Today., 36, 8, 744-746
  AUTHOR;　Matsuyama S, Sato S, Yoda Y, Kai K, Mitsuno M, Nakafusa Y, Miyazaki K.
  

Material, Commentary, Editorials, Research Report, A Comprehensive Journal Articles

• Collision tumor of a papillary and follicular thyroid carcinoma: a case report ;　2023/08
  ANNOUNCEMENT INFO.;　Thyroid Res, 16, 1, 24
  AUTHOR;　Kawasaki K, Kai K, Tanaka N, Kido S, Ibi A, Minesaki A, Yamauchi M, Kuratomi Y, Aishima S, Nakashima M, Ito M
  
• A case report of unclassified pediatric microcystic parenchymal maldevelopment of the lung;　2023/05
  ANNOUNCEMENT INFO.;　, 37, 4, 205-209
  AUTHOR;　
  
• A case of congenital capillary proliferation of the kidney (CCPK) ;　2022/06
  ANNOUNCEMENT INFO.;　Abdom Radiol (NY), 47, 6, 1961-1967
  AUTHOR;　○Ken Yamaguchi, Takahiko Nakazono, Shuichi Fukui, Takaharu Yamada, Mitsuru Noguchi, Keita Kai, Hiroyuki Irie
  
• ALK rearrangement-associated renal cell carcinoma morphologically mimicking mucinous tubular and spindle cell carcinoma: a case report;　2022/06
  ANNOUNCEMENT INFO.;　Diagn Pathol, 17, 1, 52
  AUTHOR;　Keita Kai, Shohei Tobu, Shinichi Kido, Shuji Mikami, Kengo Takeuchi, Akito Dobashi, Yuki Togashi, Mitsuru Noguchi, Shinichi Aishima
  
• A case of pulmonary mucosa-associated lymphoid tissue lymphoma transforming into diffuse large B-cell lymphoma;　2022/01
  ANNOUNCEMENT INFO.;　Japanese Journal of Clinical Radiology, 67, 1, 49-54
  AUTHOR;　*Mizuki Iyadomi, Takahiko Nagazono, Ryoko Egashira, Ken Yamaguchi, Chiho Nakashima, Keita kai, Hiroyuki Irie
  
• Fatal fat embolism syndrome during posterior spinal fusion surgery: A case report and literature review;　2021/12
  ANNOUNCEMENT INFO.;　Medicine (Baltimore), 100, 51, e28381
  AUTHOR;　○Morimoto T, Kobayashi T, Yoshihara T, Tsukamoto M, Kai K, Mawatari M
  
• Cytological Appearances of Ovarian Seromucinous Borderline Tumor in Ascites: Presentation of 2 Cases;　2021
  ANNOUNCEMENT INFO.;　Acta Cytol, 65, 5, 440-447
  AUTHOR;　Keita Kai, Mariko Hashiguchi, Makiko Kurihara, Yuya Tanaka, Sho Kitamura, Mitsuo Nakamura, Chika Shichijo, Mihoko Yamamoto-Rikitake, Ryoichi Okuma, Takako Hikari, Emi Okuma, Michiko Uchiyama, Shigehisa Aoki, Yoshifumi Nakao, Masatoshi Yokoyama, Shinichi Aishima
  
• Primary mucoepidermoid carcinoma of the liver with CRTC1-MAML2 fusion: a case report.;　2019/07
  ANNOUNCEMENT INFO.;　Diagn Pathol., 14, 1, 84
  AUTHOR;　＊Watanabe J, Kai K, Tanikawa K, Hiraki M, Mizukami N, Aishima S, Nakano T, Yamamoto H.
  
• Primary Chest Wall MYC/BCL6 Double-hit Lymphoma with t (3;7) (q27;p12) and t (8;14) (q24;q32) Translocations.;　2019/07
  ANNOUNCEMENT INFO.;　Intern Med., 58, 14, 2073-2077
  AUTHOR;　○Kamachi K, Kubota Y, Nagaie T, Yamaguchi K, Ogusu S, Kidoguchi K, Kusaba K, Kizuka-Sano H, Nishioka A, Yoshimura M, Yokoo M, Ando T, Kai K, Kojima K, Ohshima K, Sueoka E, Kimura S.
  
• Locally distributed multicentric plasmacytomas in the ileum secondary to lymphoma chemoimmunotherapy.;　2019/06
  ANNOUNCEMENT INFO.;　Ann Hematol., 98, 6, 1501-1503
  AUTHOR;　○Yokoo M, Kojima K, Sano H, Kai K, Arakawa F, Ohshima K, Matsunaga T, Kimura S.
  
• Oral ulceration: an unusual manifestation of lymphomatoid granulomatosis.;　2019/05
  ANNOUNCEMENT INFO.;　Ann Hematol., 98, 5, 1305-1307
  AUTHOR;　○Kidoguchi K, Yoshimura M, Kojima K, Ureshino H, Egashira R, Yokoo M, Kai K, Egashira Y, Ohshima K, Ando T, Kimura S.
  
• Clear Cell Carcinoma of the Uterine Cervix Presented as a Submucosal Tumor Arising in a Background of Cervical Endometriosis.;　2018
  ANNOUNCEMENT INFO.;　Int J Gynecol Pathol. , 37, 1, 88-92
  AUTHOR;　Hashiguchi M, Kai K, Nishiyama S, Nakao Y, Yokoyama M, Aishima S.
  
• A dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like features.;　2018
  ANNOUNCEMENT INFO.;　Pathol Int. , 68, 4, 262-264
  AUTHOR;　Kai K, Udo K, Yamaguchi K, Tobu S, Noguchi M, Aishima S.
  
• Synchronous mantle cell lymphoma and lung adenocarcinoma presenting in a pleural effusion: A rare tumour combination and a potential pitfall of cytodiagnosis.;　2018
  ANNOUNCEMENT INFO.;　Cytopathology. , 29, 4, 400-402
  AUTHOR;　Kai K, Ryu Y, Kamochi K, Nishioka A, Kubota Y, Nakamura M, Kimura S, Sueoka E, Aishima S.
  
• Gastric adenocarcinoma of fundic gland type with signet-ring cell carcinoma component: A case report and review of the literature.;　2018
  ANNOUNCEMENT INFO.;　World J Gastroenterol. , 24, 26, 2915-2920
  AUTHOR;　Kai K, Satake M, Tokunaga O.
  
• Primary Pulmonary Colloid Adenocarcinoma: How Can We Obtain a Precise Diagnosis?;　2018
  ANNOUNCEMENT INFO.;　Intern Med. , 57, 24, 3637-3641
  AUTHOR;　○Ogusu S, Takahashi K, Hirakawa H, Tanaka M, Komiya K, Nakamura T, Egashira R, Kai K, Takeda Y, Kimura S, Sueoka-Aragane N.
  
• A Rare Case of Kikuchi-Fujimoto Disease With Diffuse Lung Involvement Presenting a Lymphatic-like Distribution on Thin-section Computed Tomography.;　2018
  ANNOUNCEMENT INFO.;　J Thorac Imaging. , 33, 6, W51-W53
  AUTHOR;　○Egashira R, Nakazono T, Yamaguchi K, Kai K, Ono N, Yoshimura M, Irie H.
  
• Didactic surgical experience of thyroid metastasis from renal cell carcinoma: A case report.;　2018
  ANNOUNCEMENT INFO.;　World J Clin Cases. , 6, 15, 1018-1023
  AUTHOR;　○Yamauchi M, Kai K, Shibamiya N, Shimazu R, Monji M, Suzuki K, Kakinoki H, Tobu S, Kuratomi Y.
  
• A case of osimertinib-resistant lung adenocarcinoma responded effectively to alternating therapy.;　2018
  ANNOUNCEMENT INFO.;　Ann Transl Med. , 6, 23, 464
  AUTHOR;　○Hirakawa H, Komiya K, Nakashima C, Ogusu S, Nakamura T, Tanaka M, Takahashi K, Egashira Y, Kai K, Kimura S, Sueoka-Aragane N.
  
• Autopsy case of systemic EBV-positive T-cell lymphoma of childhood with marked hepatomegaly in a middle-aged man.;　2017
  ANNOUNCEMENT INFO.;　Pathol Int. , 67, 8, 431-433
  AUTHOR;　Kai K, Koga F, Araki N, Shindo T, Eguchi Y, Toda S, Aishima S.
  
• Colonic poorly differentiated adenocarcinoma with abundant cancer-associated fibroblasts diagnosed by trans-gastric endoscopic ultrasound-guided fine needle aspiration cytology.;　2017
  ANNOUNCEMENT INFO.;　Cytopathology. , 28, 5, 442-444
  AUTHOR;　Yamasaki M, Kai K, Nomura A, Kono H, Kawakubo H, Sakata Y, Mizuguchi M, Aishima S.
  
• A Case of Signet Ring Cell Carcinoma of the Gallbladder Which Was Treated by Aggressive Surgery and Intensive Adjuvant Chemotherapy.;　2017
  ANNOUNCEMENT INFO.;　J Gastrointest Cancer. , 48, 1, 83-86
  AUTHOR;　〇Hiraki M, Ueda J, Kai K, Ide T, Asai M, Ohtsuka T, Kohya N, Mukai S, Kitahara K, Noshiro H.
  
• Nasal hemophilic pseudotumor in a patient with mild hemophilia A and allergic rhinitis.;　2017
  ANNOUNCEMENT INFO.;　Pediatr Int. , 59, 2, 237-239
  AUTHOR;　〇Ogata Y, Monji M, Kai K, Matsuo M.
  
• Paraneoplastic Sarcoidosis in Multiple Myeloma.;　2017
  ANNOUNCEMENT INFO.;　Intern Med. , 56, 15, 2049-2051
  AUTHOR;　〇Kusaba K, Kojima K, Naito S, Taba M, Kai K, Ureshino H, Nishida Y, Kimura S.
  
• Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report.;　2016
  ANNOUNCEMENT INFO.;　Mol Clin Oncol., 4, 5, 695-698
  AUTHOR;　〇Nakamura J, Okuyama K, Sato H, Yoda Y, Kai K, Noshiro H.
  
• Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma with Cardiac Metastasis and Arterial Tumor Embolisms during First-Course Chemotherapy.;　2016
  ANNOUNCEMENT INFO.;　Case Rep Oncol., 9, 2, 440-446
  AUTHOR;　〇Nagai K, Suyama Y, Koga D, Nishi M, Iida C, Tashiro K, Danjo A, Kai K, Matsuo M.
  
• A Case of Radical Resection for Small Cell Carcinoma of the Bile Duct;　2015/09
  ANNOUNCEMENT INFO.;　, 76, 9, 2293-2298
  AUTHOR;　○Hirofumi SATO, Takao IDE, Keita KAI, Kenji KITAHARA, Junji UEDA, Hirokazu NOSHIRO
  
• Granulomatous reaction in hepatic inflammatory angiomyolipoma after chemoembolization and spontaneous rupture.;　2015
  ANNOUNCEMENT INFO.;　World J Gastroenterol., 21, 32, 9675-82
  AUTHOR;　Kai K, Miyosh A, Aishima S, Wakiyama K, Nakashita S, Iwane S, Azama S, Irie H, Noshiro H.
  
• Curative resection of gallbladder cancer with liver invasion and hepatic metastasis after chemotherapy with gemcitabine plus S-1: report of a case.;　2014
  ANNOUNCEMENT INFO.;　World J Surg Oncol. , 12, 326
  AUTHOR;　○Okumura T, Nakamura J, Kai K, Ide Y, Nakamura H, Koga H, Ide T, Miyoshi A, Kitahara K, Noshiro H.
  
• Metachronous aortic aneurysms due to sarcoidosis.;　2012
  ANNOUNCEMENT INFO.;　Pathol Int., 62, 5, 335-338
  AUTHOR;　Hou L, Masuda M, Akashi1 M, Kido1 S, Takase Y, Kai K, Tokunaga O
  
• Hepatoid carcinoma of the pancreas penetrating into the gastric cavity: A case report and literature review;　2012
  ANNOUNCEMENT INFO.;　Pathol Int., 62, 7, 485-490
  AUTHOR;　Kai K, Nakamura J, Ide T, Masuda M, Kitahara K, Miyoshi A, Noshiro H, Tokunaga O
  
• A case of unclassified multicystic biliary tumor with biliary adenofibroma features;　2012
  ANNOUNCEMENT INFO.;　Pathol Int., 62, 7, 506-510
  AUTHOR;　Kai K, Yakabe T, Kohya N, Miyoshi A, Iwane S, Mizuta T, Miyazaki K, Tokunaga O
  
• A unique case of gallbladder cancer arising in the neck side of segmental adenomyomatosis that mimicked hepatocellular carcinoma on contrast CT;　2012
  ANNOUNCEMENT INFO.;　Oncol. Gastroenterol. Hepatol. Reports 2012, 1, 1, 33-36
  AUTHOR;　Kai K, Ide T, Egashira R, Koga Y, Wakiyama K, Kitahara K, Irie H, Noshiro H, Tokunaga O
  
• Fibroadenoma of the gallbladder with borderline malignancy: a poorly recognized gallbladder tumor.;　2009
  ANNOUNCEMENT INFO.;　J Hepatobiliary Pancreat Surg. 16:874-877., 16, 874-877
  AUTHOR;　○Magata S, Kai K, Mori M, Edakuni G, Tokunaga O, Miyazaki K.
  
• A long-time survivor of alpha-fetoprotein-producing gastric cancer successfully treated by fluoropyrimidine-based chemotherapy: a case study;　2009
  ANNOUNCEMENT INFO.;　Clin J Gastroenterol. 2:331–337, 2, 331-337
  AUTHOR;　○Hiraki M, Sato S, Kai K, Ohtsuka T, Kohya N, Kitajima Y, Nakafusa Y, Tokunaga O, Miyazaki K.
  

General Lectures

• スライドカンファレンス　消化器・口腔;　2023/07
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Current smoking habit is a risk factor for poor surgical outcome of non-B, non-C hepatocellular carcinoma;　2018
  ANNOUNCEMENT INFO.;　AACR Annual Meeting 2018, April. 14-18
  AUTHOR;　Keita Kai, Hiroki Koga, Shinichi Aishima, Atsushi Kawaguchi, Koutaro Yamaji, Takao Ide, Junji Ueda, Hirokazu Noshiro
  
• Cytological difference of nuclei between hepatocellular carcinoma and cholangiocellular carcinoma;　2016
  ANNOUNCEMENT INFO.;　ICC2016 -19th International Congress of Cytology-, 2016, 5,28-6,1
  AUTHOR;　Kai K, Nakamura M, Aishima S
  
• HIF-1αis a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer.;　2014
  ANNOUNCEMENT INFO.;　AACR American Association for Cancer Research annual meeting, 2014.4.5-9
  AUTHOR;　○Shuusuke Miyake, Yoshiko kitajima, Jun Nakamura, Keita Kai, Kazuyoshi Yanagihara, Tomokazu Tanaka, Masatsugu Hiraki, Kohji miyazaki, Hirokazu Noshiro
  
• The attempt of tailor-made chemotherapy from biopsy specimens;　2010/08
  ANNOUNCEMENT INFO.;　9th International Conference of The Ajian Clinical Oncology Society　2010.8.25-27
  AUTHOR;　Kai K, Kitajima Y, Tokunaga O, Nakamura J, Hashiguchi K, Noshiro H, Miyazaki K
  
• Expression of carbonic anhydrase IX is predominantly regulated by site-specific DNA methylation rather than hypoxia in gastric cancer and affects the gastric carcinogenesis;　2010/08
  ANNOUNCEMENT INFO.;　9th International Conference of The Ajian Clinical Oncology Society　2010.8.25-27
  AUTHOR;　Nakamura J, Kitajima Y, Kai K, Hashiguchi K, Hiraki M, Noshiro H, Miyazaki K.
  
• A case of the invasive ductal carcinoma with reduced E-cadherin;　2010/07
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• The ribonucleotide reductase subunit M1 expression assessed by quantitative double-fluorescence immunohistochemistry is a useful chemo-resistant marker of gemcitabine in biliary tract carcinoma;　2010/02
  ANNOUNCEMENT INFO.;　8th Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association　2010,2,5-9
  AUTHOR;　Kai K, Kohya N, Nakamura J, Ohtaka K, Hashiguchi K, Hiraki M, Kitajima Y, Tokunaga O, Noshiro H, Miyazaki K.
  
• Hepatolithiasis with biliary intraductal neoplasm (BilIN);　2009/09
  ANNOUNCEMENT INFO.;　第311回九州・沖縄スライドコンファレンス　2009.9.26
  AUTHOR;　甲斐敬太
  
• Protein ratio of OPRT/TS or OPRT/(TS+DPD) evaluated by quantiative double fluorescence immunohistochemistry is a useful tool to predict drug efficacy of S-1 for gastric cancer.;　2008/04
  ANNOUNCEMENT INFO.;　American Association of Cancer Reserch annual meeting 2008, 363-363
  AUTHOR;　Kai K, Kitajima Y, Hashiguchi K ,Tokunaga O , Miyazaki K
  

Others

• A Case of Multicystic Biliary Hamartoma with a Marked Peribiliary Gland Component Successfully Treated by Purely Laparoscopic Anatomical Liver Resection;　2023
  ANNOUNCEMENT INFO.;　, 54, 996-999
  AUTHOR;　Kai K, Ide T, Tanaka T, Yukimoto K, Irie H, Noshiro H, Aishima S.
  
• Laparoscopic liver resection for local recurrence after carbon‑ion radiotherapy for hepatocellular carcinoma: A case report;　2023
  ANNOUNCEMENT INFO.;　, 28, 27, 78
  AUTHOR;　〇Tanaka T, Ide T, Itoh K, Kai K, Noshiro H.
  
• 【消化管リンパ増殖性疾患の診断アプローチの基本】経過中に小腸に再発病変を来した狭窄型DLBCLの1例　小腸悪性腫瘍との鑑別を中心に;　2023
  ANNOUNCEMENT INFO.;　, 58, 7, 929-935
  AUTHOR;　
  
• 穿刺吸引細胞診で悪性を疑った好酸性細胞型濾胞腺腫の一例;　2023
  ANNOUNCEMENT INFO.;　, 54, 49-53
  AUTHOR;　
  
• 病理診断に苦慮した右腋窩副乳癌の1例;　2023
  ANNOUNCEMENT INFO.;　, 54, 61-64
  AUTHOR;　
  
• 肺内Solitary fibrous tumorのMRI所見;　2023
  ANNOUNCEMENT INFO.;　, 50, 2, 39-43
  AUTHOR;　
  

Review Articles

• Organ-specific concept and controversy for premalignant lesions and carcinogenesis of gallbladder cancer.;　2016
  ANNOUNCEMENT INFO.;　Hepatobiliary Surg Nutr., 5, 1, 85-7
  AUTHOR;　Kai K
  
• Gallbladder cancer: Clinical and pathological approach. ;　2014
  ANNOUNCEMENT INFO.;　World J. Clin. Cases. , 2, 10, 515-21
  AUTHOR;　○Kai K, Aishima S, Miyazaki K.