Detailed Information

Research Field/Keywords for Research Field

• Bioorganic chemistry

Education

• 1990/03, Graduated
• 1992/03, Master Course, Completed
• 1995/03, Doctor Course, Completed

Employment Experience

• 1995/04 - 1996/03
• 1996/04 - 2007/03 Research Associate, Faculty of Science and Engineering, Saga University
• 2007/04 - 2010/03 Assistant Professor, Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University
• 2010/04 - 2020/02 Associate Professor, Chemistry and Applied Chemistry, Graduate School of Science and Engineering, Saga University
• 2020/03 -  *  Professor, Faculty of Science and Engineering, Saga University

Field of Specialization

• Bio-related chemistry, Organic chemistry, Bioorganic chemistry, Drug development chemistry, Chemical pharmacy

Awards

• 有機合成化学協会九州山口支部奨励賞 （2007/11）

Themes for Ongoing Research

• Desgin and Synthesis of peptide deformylase inhibitors
• Modification of thiol-based histon deacetylase inhibitor
• Insight into the methionine side-chain interaction by fluorine scan
• Synthesis of new fluorine-containing building block and its application to the synthesis of biomolecule mimic
• Elucidation of recognition mechanism on N-terminal methionine residue by means of mimetic probe molecules and application to biological defense

Research Themes in the Past

• Elucidation of recognition mechanism on N-terminal methionine residue by means of mimetic probe molecules and application to biological defense

Research Topics and Results

• Effective Position of Tryptophan Residues in Stabilization of Aib-Based Ion Channel Peptide Assemblies and Their Action to Membrane 2021/05
• Systematic Design and Validation of Ion Channel Stabilization of Amphipathic α-Helical Peptides Incorporating Tryptophan Residues 2020/12
• Comparison of Ion Channel Characteristics of Tryptophan-Incorporate Helical Peptides 2019/10
• Effect of tryptophan residues on the stability of ion channel formed by peptides 2019/10
• Can peptide deformylase produce methionine aminopeptidase inhibitors from their formylated-precursors? 2017/11
• Syntheses and biological activities of hetero dimeric formyl peptides cross-linked with amino acid residues 2016/11
• Effect of hinge sequence on the ion channel activity of Aib-containing synthetic peptides 2016/11
• Synthetic studies of monofluoroalkene-based mimetics of post-translationally modified lysine  2016/11
• Synthetic studies of post-translationally modified lysine mimetics consisting a mono-fluoroolefin unit. 2016/07
• Peptide Deformylase Processable Triazole-containing Formyl Peptide Mimetics 2016/03
• Agonistic and Antagonistic Properties of Triazole-containing Non-formyl Peptides against Formyl Peptide Receptors 2016/03
• Peptide deformylase processable triazole-containing formyl peptide mimetics 2015/11
• Synthesis and Biological Activity of Formyl Peptide Receptor 1 Agonist Dimer　with Disulfide Bond 2014/11
• Development of potent antagonists for formyl peptide receptor 1 based on Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH 2014/08
• Synthesis and Antagonist Activities of Formyl Peptide Receptor 1 Selective Antagonist Boc-FlFlF Analogs with Substitution in the First Phe Residue 2013/11
• Effects of E​/Z configuration of fluoroalkene-​containing HDAC inhibitors on selectivity for HDAC isoforms 2013/08
• Ion channel formation by charged cyclic peptides 2013/04
• Structure-activity relationship of a transmembrane peptide derived from formyl peptide receptor 1 2013/04
• A formyl peptide substituted with a conformationally constrained phenylalanine residue evokes a selective immune response in human neutrophils 2013/01
• 好中球走化性因子ホルミルペプチドfMLPの二量化におけるリンカー部位の影響 2012/11
• Investigation of the methionine side-chain recognition mechanism by a fluorine scan: The interactions at the P1’ site of E. Coli peptide deformylase 2012/07
• The cell adhesion and proliferation activities of a peptide derived from human tenascin-C are dependent on two Ile residues 2012/06
• Formation of ion-selective channel using cyclic tetrapeptides 2012/01
• Significance of Intermolecular Hydrogen-Bonding to Form Ion Channel by the Cyclic Tetrapeptide cyclo(D-Ala-Dap)2 2011/07
• Contribution of hydrophobic side-chain in cyclic tetrapeptide forming ion channel 2011/03
• Contribution of hydrophobic side-chain in cyclic tetrapeptide forming ion channel 2010/12
• The elucidation of the conformational requirements for methionine side-chain interaction with FPR by using fluorinated fMLP analogs 2010/12
• Synthesis and biological activity of short chain peptaibol cervinin A 2010/12
• Synthesis and biological activities of Cathelicidin pepties LL37 in human neutrophiles 2010/12
• Synthesis and biological activities of dimeric formyl peptide antagonists 2010/12
• Regulation of ion channel forming based on cyclic peptides 2010/12
• Synthesis and biological activity of fMLP analogs based on the 1st residue replacement by fluorine containing Met mimic 2010/12
• Hybrid inhibitors consisting of both thiol-based FTase and HDAC inhibitors 2010/12
• Peptaibol Derived Helix-Kink Motif Facilitates Channel Forming of the Artificial α-Aminoisobutyric Acid Rich Helices 2010/09
• Trans-bilayer ion conduction by proline containing cyclic hexapeptides and effects of amino acid substitutions on ion conducting properties 2010/05
• Methionine Analogs with the γ-Carbon and Sulfur Atoms Replaced by a Fluoroalkene Unit 2010/04
• Amino Acid Sequence Dependence of Ion Channel Activity by Cyclic Tetrapeptides 2010/04
• Receptor Subtype Selectivity of Dimeric Chemotactic Antagonists 2010/04
• Synthesis and Evaluation of HDAC Inhibitors Utilizing Intramolecular Acyl Transfer Activation 2010/03
• Fluoroalkene Modification of Mercaptoacetamide-based Histone Deacetylase Inhibitors 2010/01
• Methionine Analogues with the γ-Carbon and Sulfur Atoms Replaced by a Fluoroalkene Unit 2009/11
• Receptor Subtype Selectivity of Dimeric Chemotactic Antagonists 2009/11
• Amino Acid Sequence Dependence of Ion Channel Activity by Cyclic Tetrapeptides 2009/11
• Neutrophils Activation by Hymenamides from Marine Sponges 2009/05
• Synthesis and Biological Activity of Dimeric Chemotactic Peptide Antagonist 2009/03
• Insight into Methionine Side-Chain Recognition by the FPR Utilizing Sulfur Mimitics 2009/03
• Synthesis and Priming Activities of Cyclic Peptides, Hymenamides 2009/03
• Synthesis and Biological Activity of Alamethicin Analogs Enhanced by Electrostatic Interaction 2009/03
• Synthesis and Biological Activity of Transmembrane Peptides Derived from FPR Family Receptors 2009/03
• Synthesis and Biological Activity of Cyclic Peptide, Hymenamide Analogs 2009/03
• Transmembrane Peptides are Useful Tools for Study of Membrane Proteins Function 2008/08
• Neutrophil Priming with Transmembrane Peptides Derived from Formyl Peptide Receptor Subtypes 2008/07
• Synthesis and biological activity of transmembrane peptides derived from membrane proteins 2008/01
• Synthesis and biological activities of natural cyclic peptides 2008/01
• Synthesis of HDAC-FTase hybrid inhibitors and their HL60 cell growth-inhibitory activity 2008/01
• Ion-channel formation assisted by electrostatic interhelical interaction in covalently dimerized amphiphilic helical peptides 2008
• Synthesis and biological activity of synthetic peptide MMK-1 analogs 2008
• Synthesis and ion conductance of cervinin peptides 2008
• Enhancement of ion channel formation by electrostatic interaction incorporated in dimeric helical peptide 2008
• Differential Receptor Recognition by Dmt-Containing Enkephalin Dimers Cross-Linked by Phenylenediamines 2008
• Effects of subtype selective agonists for primed neutrophils by FPR transmembrane peptides 2007/12
• "Ion channel formation of dimeric peptide enhanced by electrostatic interaction " 2007/06
• Synthesis and biological activity of transmembrane peptides derived from FPR family receptors 2007/06
• Synthesis and biological activity of cyclic peptide, hymenamide analogs 2007/06
• Conformational effects of cyclic hexapeptides for ion channel properties 2007/05
• Comparison study of ion chanel activities of homo-dimerized and hetero-dimerized amphiphilic helical model peptides 2006/11
• Synthesis of FPR-derived transmembrane peptides containing photoaffinity amino acid 2006/11
• "Synthesis and Structural Properties of Cross-linked Amphiphilic Helix Peptides Containing Unusual Amino Acid" 2006/08
• イオンチャンネルペプチドデザインを目的とした機能性コア配列の検討 2006/07
• Effect of synthetic peptides derived from formyl peptide receptor on superoxide anion productionin human neutrophils 2006/06
• Facile synthesis of (S)-5,5-Difluoronorleucine and its incorporation in biologically active peptides as an methionine mimetic 2006
• Superoxide Production in Human Neutrophils Is Enhanced by Treatment with Transmembrane Peptides Derived from Human Formyl Peptide Receptor 2006
• Effect of Ring Size Alteration for Ion Channel Activities of Cyclic Peptides 2006
• Signal Transduction of Chemotactic Non-Formyl Peptide and Selective for Formyl Peptide Receptor 2006
• Synthesis of Transmembrane Peptides Derived from Human Formyl Peptide Receptor and Influence on Biological Activities of Human Neutrophils 2006
• CF2 substitution on sulfur atom in methionine residue: Distinct fMLP agonistic/antagonistic behavior by N-formyl/N-t-buthyloxycarbonyl switching 2005/12
• Fluoroolefin mimicking at acetyllysine side-chain amide: preparation of Boc- and Fmoc-protected 2-amino-8-fluoro-7-nonenic acid 2005/12
• Structures and Ion-Channel Activities of Cyclic Peptide Channel Nanotube 2005/12
• Synthesis and Elastase-Release Inhibition of Hymenamide B Analogs for Human Neutrophiles 2005/12
• Synthesis and Antagonistic Activities of fMLP Analogs Containing Conformationaly　Restricted Amino Acid Derivatives 2005/12
• Synthesis and Biological Properties of Transmembrane Peptides Derived from G Protein-Coupled Receptor 2005/11
• Effect of Anti-Parallel Dimerization for Ion Channel Properties of Helical Model Peptides 2005/11
• Synthesis of Cyclic Peptides Derived from Marine Sponges 2005/11
• Structure-Activity Relationships of Human Formyl Peptide Receptor Antagonist Containing Cycropropane Derivatives 2005/11
• Synthesis of Transmembrane Peptides Derived from Human Formyl Peptide Receptor and Influence on Biological Activities of Human Neutrophils 2005/10
• Effect of Ring Size Alteration for Ion Channel Activities of Cyclic Peptides 2005/10
• Signal Transduction of Chemotactic Non-Formyl Peptide and Selective for Formyl Peptide Receptor 2005/10
• Ion Channel Activities Effected by Alteration about Hydrophobicities and Ring Size of Cyclic Peptides 2005/10
• Enhancement of Chemotaxis for Human Neutrophils by Pretreatment with Porphyran 2005/10
• Ion Channel Activities and Mechanisms of Ion Conduction about Cyclic Hexapeptides 2005/06
• Synthesis and Biological Activities of Proline Rich Cyclic Heptapeptide Hymemanide B Analogs 2005/06
• Synthesis and Biological Activities of fMLP Analogs Containing 2,3-Cyclopropane Amino Acid Derivatives 2005/06
• Difluoromethylene group can act as a sulfur mimetic in methionine-containing chemotactic peptide 2005/04
• Structure-Activity Relationships of Channel Forming Cyclopeptides 2005/04
• Ion-Channel Properties of Cyclic Hexapeptide cyclo(Pro-Xxx-Yyy)2 2005
• Solid-Phase Synthesis of Tyrosine-Containing Cyclic Peptides 2005
• Synthesis and Biological Activity of Urease-related Peptides Generated from Helicobacter Pylori 2005
• L-5,5-Difluoronorleucine as an Oxidation-Resistant Methionine Mimic: Facile Synthesis and Its Application on Chemotactic Peptide, fMLP 2005
• Solid Phase Synthesis of Cyclic Peptides Containing Tyr Residue 2004/11
• Synthesis of Dimeric Tropoelastin Analogs, H-(Val-Pro-Gly-Val-Gly)n-Gly-Gly-Cys-NH2 2004/11
• Ion-channel properties of cyclic peptides 2004/11
• Synthesis of helical peptides containing Met residres 2004/11
• Application of Oxidation-Resistant Methionine Mimic on Chemotactic Formyl-Methionyl Peptide 2004/11
• Ion-Channel Properties of Cyclic Hexapeptide cyclo(Pro-Xxx-Yyy)2 2004/10
• Solid-Phase Synthesis of Tyrosine-Containing Cyclic Peptides 2004/10
• Synthesis and Biological Activity of Urease-related Peptides Generated from Helicobacter Pylori 2004/10
• L-5,5-Difluoronorleucine as an Oxidation-Resistant Methionine Mimic: Facile Synthesis and Its Application on Chemotactic Peptide, fMLP 2004/10
• Syhnthesis and biological activity of ion-channel peptides containing unusual amino acid 2004/10
• Synthesis and properties of Aib-peptide containing Met and Met(O) residues 2004/10
• Synthesis of a Fluoroalkene Isoster of Acetyllysine 2004
• Synthesis and Ion-Channel Activity of Assembled Aib-Model Peptides 2004
• Synthesis of Chemotactic Peptide Analogs with a Photoaffinity Cross-linker as New Probes for Analysis of Receptor-Ligand Interaction. 2003
• Synthesis and Chemotaxis of fMLP analogs and Nonformylated peptides 2003
• Effect of $\alpha$, $\alpha$-Dialkyl Amino Acids on the Protease Resistance of Peptides 2003
• Synthesis and Calcium Binding of Oligomeric Tropoelastion Analogs 2003

Original Articles

• Induction of cellular senescence in fibroblasts through β1-integrin activation by tenascin-C-derived peptide and its protumor effect;　2021/09
  ANNOUNCEMENT INFO.;　American Journal of Cancer Reserch, 11, 9, 4364-4379
  AUTHOR;　Motomichi Fujita, Manabu Sasada, Mayu Eguchi, Takuya Iyoda, Shin Okuyama, Takuro Osawa, Kenta Tsuzuranuki, Mamoru Sakamoto, Yu Hagihara, Masaki Matsumura, Satoshi Osada, Hiroaki Kodama, Yoshikazu Higami, Fumio Fukai
  
• Effective Position of Tryptophan Residues in Stabilization of Aib-Based Ion Channel Peptide Assemblies and Their Action to Membrane;　2021/05
  ANNOUNCEMENT INFO.;　, 71
  AUTHOR;　Keita Shigedomi, Kiyohiko Seki, Toshihisa Ueda, Satoshi Osada, Masoud Jelokhani-Niaraki, and Hiroaki Kodama
  
• Biofunctional Peptide FNIII14: Therapeutic Potential;　2021/04
  ANNOUNCEMENT INFO.;　Encyclopedia, 1, 350–35
  AUTHOR;　Motomichi Fujita, Manabu Sasada, Takuya Iyoda, Satoshi Osada, Hiroaki Kodama, Fumio Fukai
  
• Anoikis resistance conferred by tenascin-C-derived peptide TNIIIA2 and its disruption by integrin inactivation;　2021/01
  ANNOUNCEMENT INFO.;　Biochemical and Biophysical Research Communications, 536, 14-19
  AUTHOR;　Motomichi Fujita, Manabu Sasada, Takuya Iyoda, Reo Nagai, Chikako Kudo, Tetsuya Yamamoto, Satoshi Osada, Hiroaki Kodama, Fumio Fukai
  
• Systematic Design and Validation of Ion Channel Stabilization of Amphipathic α-Helical Peptides Incorporating Tryptophan Residues;　2020/12
  ANNOUNCEMENT INFO.;　ACS Omega, 6, 1, 723–732
  AUTHOR;　Keita Shigedomi, Satoshi Osada, Masoud Jelokhani-Niaraki, and Hiroaki Kodama
  
• Exposure of the cryptic de-adhesive site FNIII14 in fibronectin molecule and its binding to membrane-type eEF1A induce migration and invasion of cancer cells via β1-integrin inactivation;　2020/11
  ANNOUNCEMENT INFO.;　American Journal of Cancer Research, 10, 11, 3990-4004
  AUTHOR;　
  
• Peptide Deformylase Processable Triazole-containing Formyl Peptide Mimetics;　2016/03
  ANNOUNCEMENT INFO.;　Peptide Science 2015, 159-162
  AUTHOR;　H. Osako, J. Taira, Y. Higashimoto, H. Kodama, S. Osada
  
• Development of potent antagonists for formyl peptide receptor 1 based on Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH;　2014/08
  ANNOUNCEMENT INFO.;　Bioorg. Med. Chem., 22, 15, 3824-3828
  AUTHOR;　R. Hayashi, T. Kitajima, H. Mizugushi, M. Fujimoto, A. Yamaguchi, S. Koga, Y. Koga, S. Osada, H. Kodama
  
• Effects of E​/Z configuration of fluoroalkene-​containing HDAC inhibitors on selectivity for HDAC isoforms;　2013/08
  ANNOUNCEMENT INFO.;　Chemistry Letters, 42, 8, 833-835
  AUTHOR;　Y. Chuman, M. Ueyama, S. Sano, F. Wu, Y. Kiyota, T. Higashi, S. Osada, K. Sakaguchi
  
• Ion channel formation by charged cyclic peptides;　2013/04
  ANNOUNCEMENT INFO.;　Peptide Science 2012, 195-198
  AUTHOR;　T. Suga, S. Osada, H. Kodama
  
• Structure-activity relationship of a transmembrane peptide derived from formyl peptide receptor 1;　2013/04
  ANNOUNCEMENT INFO.;　Peptide Science 2012, 221-224
  AUTHOR;　R. Hayashi, R. Yamaguchi, Y. Koga, I. Fujita, S. Osada, Y. Hamasaki, H. Kodama
  
• A formyl peptide substituted with a conformationally constrained phenylalanine residue evokes a selective immune response in human neutrophils;　2013/01
  ANNOUNCEMENT INFO.;　Bioorg. Med. Chem., 21, 3, 668-675
  AUTHOR;　R. Hayashi, M. Miyazaki, S. Osada, H. Kawasaki, I. Fujita, Y. Hamasaki, H. Kodama
  
• The cell adhesion and proliferation activities of a peptide derived from human tenascin-C are dependent on two Ile residues;　2012/06
  ANNOUNCEMENT INFO.;　Bioorg. Med. Chem., 20, 15, 4608-4613
  AUTHOR;　R. Hayashi, S. Miura, Y. Saito, S. Osada, T. Iyoda, F. Fukai, H. Kodama
  
• Formation of ion-selective channel using cyclic tetrapeptides;　2012/01
  ANNOUNCEMENT INFO.;　Bioorg. Med. Chem., 20, 1, 42-46
  AUTHOR;　T. Suga, S. Osada, H. Kodama
  
• Significance of Intermolecular Hydrogen-Bonding to Form Ion Channel by the Cyclic Tetrapeptide cyclo(D-Ala-Dap)2;　2011/07
  ANNOUNCEMENT INFO.;　Peptides: Building Bridges, 156-157
  AUTHOR;　T. Suga, S. Osada, H. Kodama
  
• Contribution of hydrophobic side-chain in cyclic tetrapeptide forming ion channel;　2011/03
  ANNOUNCEMENT INFO.;　Peptides Science 2010, 130
  AUTHOR;　T. Suga, J. Taira, S. Osada, H. Kodama
  
• Peptaibol Derived Helix-Kink Motif Facilitates Channel Forming of the Artificial α-Aminoisobutyric Acid Rich Helices;　2010/09
  ANNOUNCEMENT INFO.;　Int. J. Petp. Res. Ther., 16, 277-282
  AUTHOR;　J. Taira, M. Shibue, S. Osada, H. Kodama
  
• Trans-bilayer ion conduction by proline containing cyclic hexapeptides and effects of amino acid substitutions on ion conducting properties;　2010/05
  ANNOUNCEMENT INFO.;　Bull. Chem. Soc. Jpn., 83, 638-688
  AUTHOR;　J. Taira, S. Osada, R. Hayashi, T. Ueda, M. Jelokhani-Niaraki, H. Aoyagi, H. Kodama
  
• Methionine Analogs with the γ-Carbon and Sulfur Atoms Replaced by a Fluoroalkene Unit;　2010/04
  ANNOUNCEMENT INFO.;　Peptides Science 2009, 123-126
  AUTHOR;　S. Osada, R. Takabatake, D. Sugiyama, Y. Hamasaki, I. Fujita, and Hiroaki Kodama
  
• Amino Acid Sequence Dependence of Ion Channel Activity by Cyclic Tetrapeptides;　2010/04
  ANNOUNCEMENT INFO.;　Peptides Science 2009, 195-198
  AUTHOR;　T. Suga, J. Taira, S. Osada, H. Kodama
  
• Receptor Subtype Selectivity of Dimeric Chemotactic Antagonists;　2010/04
  ANNOUNCEMENT INFO.;　Peptides Science 2009, 199-202
  AUTHOR;　D. Sugiyama, Y. Hirakawa, H. Shinmachi, S. Osada, I. Fujita, Y. Hamasaki, and Hiroaki Kodama
  
• Fluoroalkene Modification of Mercaptoacetamide-based Histone Deacetylase Inhibitors;　2010/01
  ANNOUNCEMENT INFO.;　Bioorg. Med. Chem., 18, 2, 605-611
  AUTHOR;　S. Osada, S. Sano, M. Ueyama, Y. Chuman, H. Kodama, and K. Sakaguchi
  
• Synthesis and Biological Activity of Dimeric Chemotactic Peptide Antagonist;　2009/03
  ANNOUNCEMENT INFO.;　Peptides Science 2008, 253-256
  AUTHOR;　D. Sugiyama, Y. Hirakawa, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Insight into Methionine Side-Chain Recognition by the FPR Utilizing Sulfur Mimitics;　2009/03
  ANNOUNCEMENT INFO.;　Peptides Science 2008, 249-252
  AUTHOR;　S. Osada, D. Sugiyama, M. Sato, Y. Hamasaki, I. Fujita, and H. Kodama
  
• Synthesis and Priming Activities of Cyclic Peptides, Hymenamides;　2009/03
  ANNOUNCEMENT INFO.;　Peptides Science 2008, 239-242
  AUTHOR;　M. Onai, D. Sugiyama, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Synthesis and Biological Activity of Alamethicin Analogs Enhanced by Electrostatic Interaction;　2009/03
  ANNOUNCEMENT INFO.;　Peptides Science 2008, 245-248
  AUTHOR;　S. Imamura, J. Taira, T. Suga, S. Osada, and H. Kodama
  
• Synthesis and Biological Activity of Transmembrane Peptides Derived from FPR Family Receptors;　2009/03
  ANNOUNCEMENT INFO.;　Peptides, 2008, 331-332
  AUTHOR;　D. Sugiyama, R. Hayashi, S. Osada, Y. Hamasaki, I. Fujita, and H. Kodama
  
• Synthesis and Biological Activity of Cyclic Peptide, Hymenamide Analogs;　2009/03
  ANNOUNCEMENT INFO.;　Peptides, 2009, 323-324
  AUTHOR;　Y. Shiki, M. Onai, D. Sugiyama, S. Osada, I. Fujita, and H. Kodama
  
• Ion-channel formation assisted by electrostatic interhelical interaction in covalently dimerized amphiphilic helical peptides;　2008
  ANNOUNCEMENT INFO.;　Biochemistry, 47, 12, 3705-3714
  AUTHOR;　J. Taira, M. Jelokhani-Niaraki, S. Osada, F. Kato, and H. Kodama
  
• Synthesis and biological activity of synthetic peptide MMK-1 analogs;　2008
  ANNOUNCEMENT INFO.;　Peptides Science 2007, 269-272
  AUTHOR;　D. Sugiyama, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Synthesis and ion conductance of cervinin peptides;　2008
  ANNOUNCEMENT INFO.;　Peptides Science 2007, 277-280
  AUTHOR;　J. Ito, J. Taira, S. Osada, F. Kato, and H. Kodama
  
• Enhancement of ion channel formation by electrostatic interaction incorporated in dimeric helical peptide;　2008
  ANNOUNCEMENT INFO.;　Peptides Science 2007, 285-288
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, T. Ehara, and H. Kodama
  
• Differential Receptor Recognition by Dmt-Containing Enkephalin Dimers Cross-Linked by Phenylenediamines;　2008
  ANNOUNCEMENT INFO.;　Peptides Science 2007, 303-306
  AUTHOR;　N. Inokuchi, K. Isozaki, Y. Tsuda, Y. Okada, S. Osada, T. Nose, T. Costa, and Y. Shimohigashi
  
• Facile synthesis of (S)-5,5-Difluoronorleucine and its incorporation in biologically active peptides as an methionine mimetic;　2006
  ANNOUNCEMENT INFO.;　Heterocycles,, 67, 421-431
  AUTHOR;　S. Osada, T. Ishimaru, H. Kawasaki, H. Kodama
  
• Superoxide Production in Human Neutrophils Is Enhanced by Treatment with Transmembrane Peptides Derived from Human Formyl Peptide Receptor;　2006
  ANNOUNCEMENT INFO.;　J. Biochem., 139, 981-988
  AUTHOR;　R. Hayashi, S. Osada, M. Yoshiki, D. Sugiyama, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Effect of Ring Size Alteration for Ion Channel Activities of Cyclic Peptides;　2006
  ANNOUNCEMENT INFO.;　Peptides Science 2005, 245-248
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, T. Ehara, and H. Kodama
  
• Signal Transduction of Chemotactic Non-Formyl Peptide and Selective for Formyl Peptide Receptor;　2006
  ANNOUNCEMENT INFO.;　Peptides Science 2005, 249-252
  AUTHOR;　M. Yoshiki, R. Hayashi, D. Sugiyama, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Synthesis of Transmembrane Peptides Derived from Human Formyl Peptide Receptor and Influence on Biological Activities of Human Neutrophils;　2006
  ANNOUNCEMENT INFO.;　Peptides Science 2005, 241-244
  AUTHOR;　R. Hayashi, D. Sugiyama, M. Yoshiki, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Ion-Channel Properties of Cyclic Hexapeptide cyclo(Pro-Xxx-Yyy)2;　2005
  ANNOUNCEMENT INFO.;　Peptides Science 2004 , 531-534
  AUTHOR;　J. Taira, S. Osada, R. Hayashi, M. Yoshiki, S. Tatebe, T. Ueda, T. Ehara, H. Kodama
  
• Solid-Phase Synthesis of Tyrosine-Containing Cyclic Peptides;　2005
  ANNOUNCEMENT INFO.;　Peptides Science 2004 , 535-538
  AUTHOR;　 A. Nakamura, S. Tatebe, J. Taira, S. Osada, H. Ooba, S. Yasuda, H. Kodama
  
• Synthesis and Biological Activity of Urease-related Peptides Generated from Helicobacter Pylori;　2005
  ANNOUNCEMENT INFO.;　Peptides Science 2004 , 573-576
  AUTHOR;　M. Yoshiki, K. Tsuge, T. Yoshimura, K. Koganemaru, I. Fujita, Y. Hamasaki, S. Osada, H. Kodama
  
• L-5,5-Difluoronorleucine as an Oxidation-Resistant Methionine Mimic: Facile Synthesis and Its Application on Chemotactic Peptide, fMLP;　2005
  ANNOUNCEMENT INFO.;　Peptides Science 2004, 641-645
  AUTHOR;　S. Osada, H. Kawasaki, T. Ishimaru, M. Yoshiki, Y. Hamasaki, I. Fujita, H. Kodama
  
• Synthesis of a Fluoroalkene Isoster of Acetyllysine;　2004
  ANNOUNCEMENT INFO.;　Peptides Science 2003 , 269-272
  AUTHOR;　S. Osada, H. Kodama
  
• Synthesis and Ion-Channel Activity of Assembled Aib-Model Peptides;　2004
  ANNOUNCEMENT INFO.;　Peptides Science 2003, 327-330
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, H. Kodama
  
• Synthesis of Chemotactic Peptide Analogs with a Photoaffinity Cross-linker as New Probes for Analysis of Receptor-Ligand Interaction.;　2003
  ANNOUNCEMENT INFO.;　Protein, Pept. Lett, 10, 147 - 153
  AUTHOR;　M. Shibue, M. Yoshiki, M. Miyazaki, I. Fujita, S. Osada, S. Yasuda, H. Nakamura, Y. Hamasaki, M. Kondo, H. Maeda, H. Kodama, H. Shimizu
  
• Synthesis and Chemotaxis of fMLP analogs and Nonformylated peptides;　2003
  ANNOUNCEMENT INFO.;　Peptides Science 2002, 269-272
  AUTHOR;　M. Yoshiki, H. Kawasaki, R. Hayashi, S. Osada, I. Fujita, Y. Hamasaki H. Kodama
  
• Effect of $\alpha$, $\alpha$-Dialkyl Amino Acids on the Protease Resistance of Peptides;　2003
  ANNOUNCEMENT INFO.;　Biosci. Biotechnol. Biochem., 67, 2269-2272
  AUTHOR;　H. Yamaguchi, H. Kodama, S. Osada, F. Kato, M. Jelokhani Niaraki, M. Kondo
  
• Synthesis and Calcium Binding of Oligomeric Tropoelastion Analogs;　2003
  ANNOUNCEMENT INFO.;　Biopolymers, Peptide Science, 71, 320
  AUTHOR;　H. Kodama, S. Ueno, S. Osada, I. Maeda, K. Okamoto, M. Kondo
  
• Photoaffinity Labeling of Formylpeptide Receptors by fMLP Analogs;　2002
  ANNOUNCEMENT INFO.;　Peptide Science 2001, 153-156
  AUTHOR;　M. Miyazaki, M. Shibue, M. Yoshiki, S. Osada, H. Kodama, I. Fujita, Y. Hamasaki, H. Maeda, M. Kondo
  

General Lectures

• Comparison of Ion Channel Characteristics of Tryptophan-Incorporate Helical Peptides;　2019/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Effect of tryptophan residues on the stability of ion channel formed by peptides;　2019/10
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Can peptide deformylase produce methionine aminopeptidase inhibitors from their formylated-precursors?;　2017/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Syntheses and biological activities of hetero dimeric formyl peptides cross-linked with amino acid residues;　2016/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Effect of hinge sequence on the ion channel activity of Aib-containing synthetic peptides;　2016/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Synthetic studies of monofluoroalkene-based mimetics of post-translationally modified lysine ;　2016/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Yusei Tokisada, Hiroaki Kodama, Satoshi Osada
  
• Synthetic studies of post-translationally modified lysine mimetics consisting a mono-fluoroolefin unit.;　2016/07
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Agonistic and Antagonistic Properties of Triazole-containing Non-formyl Peptides against Formyl Peptide Receptors;　2016/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　K. ARIMA, K. KURIHARA, Y. KATAFUCHI, H. KODAMA, S. OSADA
  
• Peptide deformylase processable triazole-containing formyl peptide mimetics;　2015/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Synthesis and Biological Activity of Formyl Peptide Receptor 1 Agonist Dimer　with Disulfide Bond;　2014/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Yuya Koga、Shuichiro Koga、 Ryo Hayashi、 Yukari Katafuchi、 Ichiro Fujita、Satoshi Osada、 Hiroaki Kodama
  
• Synthesis and Antagonist Activities of Formyl Peptide Receptor 1 Selective Antagonist Boc-FlFlF Analogs with Substitution in the First Phe Residue;　2013/11
  ANNOUNCEMENT INFO.;　4th Asia-Pacific International Peptide Symposium/50th Japanese Peptide Symposium
  AUTHOR;　Yuya Koga, Toshiki Kitajima, Ryo Hayashi, Satoshi Osada, Ichiro Fujita, Yuhei Hamasaki and Hiroaki Kodama
  
• 好中球走化性因子ホルミルペプチドfMLPの二量化におけるリンカー部位の影響;　2012/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Investigation of the methionine side-chain recognition mechanism by a fluorine scan: The interactions at the P1’ site of E. Coli peptide deformylase;　2012/07
  ANNOUNCEMENT INFO.;　
  AUTHOR;　S. Osada, H. Kitamura, M. Okitani, R. Hayashi, J. Taira, Y. Higashimoto, H. Kodama
  
• Contribution of hydrophobic side-chain in cyclic tetrapeptide forming ion channel;　2010/12
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Torao Suga, Satoshi Osada, Hiroaki Kodama
  
• The elucidation of the conformational requirements for methionine side-chain interaction with FPR by using fluorinated fMLP analogs;　2010/12
  ANNOUNCEMENT INFO.;　5th International Peptide Symposium/47th Japanese Peptide Symposium
  AUTHOR;　R. Takabatake, Ryo Yamaguchi, Satoshi Osada, Hiroaki Kodama
  
• Synthesis and biological activity of short chain peptaibol cervinin A;　2010/12
  ANNOUNCEMENT INFO.;　The 2010 International Chemical Congress of Pacific Basin Societies (2010 PacifiChem)
  AUTHOR;　Y. Kuriyama, T. Suga, S. Osada, H. Kodama
  
• Synthesis and biological activities of Cathelicidin pepties LL37 in human neutrophiles;　2010/12
  ANNOUNCEMENT INFO.;　The 2010 International Chemical Congress of Pacific Basin Societies (2010 PacifiChem)
  AUTHOR;　H. Shinmachi, R. Yamaguchi, D. Sugiyama, S. Osada, I. Fujita, Y. Hamasaki, H. Kodama
  
• Synthesis and biological activities of dimeric formyl peptide antagonists;　2010/12
  ANNOUNCEMENT INFO.;　The 2010 International Chemical Congress of Pacific Basin Societies (2010 PacifiChem)
  AUTHOR;　R. Yamaguchi, D. Sugiyama, S. Osada, I. Fujita, Y. Hamasaki, H. Kodama
  
• Regulation of ion channel forming based on cyclic peptides;　2010/12
  ANNOUNCEMENT INFO.;　The 2010 International Chemical Congress of Pacific Basin Societies (2010 PacifiChem)
  AUTHOR;　T. Suga, S. Osada, H. Kodama
  
• Synthesis and biological activity of fMLP analogs based on the 1st residue replacement by fluorine containing Met mimic;　2010/12
  ANNOUNCEMENT INFO.;　The 2010 International Chemical Congress of Pacific Basin Societies (2010 PacifiChem)
  AUTHOR;　R. Takabatake, D. Sugiyama, S. Osada, Y. Hamasaki, I. Fujita, H. Kodama
  
• Hybrid inhibitors consisting of both thiol-based FTase and HDAC inhibitors;　2010/12
  ANNOUNCEMENT INFO.;　The 2010 International Chemical Congress of Pacific Basin Societies (2010 PacifiChem)
  AUTHOR;　S. Osada, S. Sano, K. Sakaguchi, H. Kodama
  
• Synthesis and Evaluation of HDAC Inhibitors Utilizing Intramolecular Acyl Transfer Activation;　2010/03
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Methionine Analogues with the γ-Carbon and Sulfur Atoms Replaced by a Fluoroalkene Unit;　2009/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　S. Osada, R. Takabatake, D. Sugiyama, Y. Hamasaki, I. Fujita, and H. Kodama
  
• Receptor Subtype Selectivity of Dimeric Chemotactic Antagonists;　2009/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　D. Sugiyama, Y. Hirakawa, H. Shinmachi, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Amino Acid Sequence Dependence of Ion Channel Activity by Cyclic Tetrapeptides;　2009/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　T. Suga, J. Taira, S. Osada, and H. Kodama
  
• Neutrophils Activation by Hymenamides from Marine Sponges;　2009/05
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Transmembrane Peptides are Useful Tools for Study of Membrane Proteins Function;　2008/08
  ANNOUNCEMENT INFO.;　17th Meeting of Methods in Protein Structure Analysis (Sapporo, Japan)
  AUTHOR;　Daisuke Sugiyama, Satoshi Osada, Ryo Hayashi, Hiroshi Yamaguchi, Masoud Jelokhani-Niaraki, Ichiro Fujita and Hiroaki Kodama
  
• Neutrophil Priming with Transmembrane Peptides Derived from Formyl Peptide Receptor Subtypes;　2008/07
  ANNOUNCEMENT INFO.;　22nd Annual Symposium of The Protein Society (San Diego, CA, U.S.A)
  AUTHOR;　Daisuke Sugiyama, Satoshi Osada, Ichiro Fujita, Yuhei Hamasaki and Hiroaki Kodama
  
• Synthesis and biological activity of transmembrane peptides derived from membrane proteins;　2008/01
  ANNOUNCEMENT INFO.;　
  AUTHOR;　D. Sugiyama, D. Shibata, S. Osada, I. Fujita, Y. Hamasaki, H. Kodama
  
• Synthesis and biological activities of natural cyclic peptides;　2008/01
  ANNOUNCEMENT INFO.;　The 1st Saga University and Daegu University Joint Seminar(佐賀大学（佐賀）)
  AUTHOR;　M. Onai, D. Sugiyama, D. Shibata, S. Osada, I. Fujita, Y. Hamasaki, H. Kodama
  
• Synthesis of HDAC-FTase hybrid inhibitors and their HL60 cell growth-inhibitory activity;　2008/01
  ANNOUNCEMENT INFO.;　The 1st Saga University and Daegu University Joint Seminar(佐賀大学（佐賀）)
  AUTHOR;　S. Sano, D. Sugiyama, S. Osada, H. Kodama
  
• Effects of subtype selective agonists for primed neutrophils by FPR transmembrane peptides;　2007/12
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• "Ion channel formation of dimeric peptide enhanced by electrostatic interaction ";　2007/06
  ANNOUNCEMENT INFO.;　20th American Peptide Society Symposium(Palais des congres de Montreal (Montreal))
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, T. Ehara, H. Kodama
  
• Synthesis and biological activity of transmembrane peptides derived from FPR family receptors;　2007/06
  ANNOUNCEMENT INFO.;　20th American Peptide Society Symposium(Palais des congres de Montreal (Montreal))
  AUTHOR;　D. Sugiyama, R. Hayashi, S. Osada, Y. Hamasaki, I. Fujita, H. Kodama
  
• Synthesis and biological activity of cyclic peptide, hymenamide analogs;　2007/06
  ANNOUNCEMENT INFO.;　20th American Peptide Society Symposium(Palais des congres de Montreal (Montreal))
  AUTHOR;　Y. Shiki, M. Onai, D. Sugiyama, S. Osada, I. Fujita, H. Kodama
  
• Conformational effects of cyclic hexapeptides for ion channel properties;　2007/05
  ANNOUNCEMENT INFO.;　20th American Peptide Society Symposium(Palais des congres de Montreal (Montreal))
  AUTHOR;　J. Taira, S. Imamura, S. Osada, M. Jelokhani-Niaraki, T. Ehara, H. Kodama
  
• Comparison study of ion chanel activities of homo-dimerized and hetero-dimerized amphiphilic helical model peptides;　2006/11
  ANNOUNCEMENT INFO.;　International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting(パシフィコ横浜（横浜）)
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, T. Ehara and H. Kodama
  
• Synthesis of FPR-derived transmembrane peptides containing photoaffinity amino acid;　2006/11
  ANNOUNCEMENT INFO.;　International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting(パシフィコ横浜（横浜）)
  AUTHOR;　D. Sugiyama, R. Hayashi, S. Osada, I. Fujita, Y. Hamasaki and H. Kodama
  
• "Synthesis and Structural Properties of Cross-linked Amphiphilic Helix Peptides Containing Unusual Amino Acid";　2006/08
  ANNOUNCEMENT INFO.;　"20th Symposium of The Protein Society"(Manchester Grand Hyatt Hotel (San Diego, CA))
  AUTHOR;　"H. Kodama, J. Taira, S. Osada, T. Ehara"
  
• イオンチャンネルペプチドデザインを目的とした機能性コア配列の検討;　2006/07
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  
• Effect of synthetic peptides derived from formyl peptide receptor on superoxide anion productionin human neutrophils;　2006/06
  ANNOUNCEMENT INFO.;　20th IUBMB International Congress of Biochemistry and Molecular Biology, and 11th FAOBMB Congress(国立京都国際会館（京都）)
  AUTHOR;　R. Hayashi, D. Sugiyama, M. Yoshiki, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• CF2 substitution on sulfur atom in methionine residue: Distinct fMLP agonistic/antagonistic behavior by N-formyl/N-t-buthyloxycarbonyl switching;　2005/12
  ANNOUNCEMENT INFO.;　Pacifichem 2005(ハワイ)
  AUTHOR;　S. Osada, D. Sugiyama, H. Kawasaki, Y. Hamasaki, I. Fujita, and H. Kodama
  
• Fluoroolefin mimicking at acetyllysine side-chain amide: preparation of Boc- and Fmoc-protected 2-amino-8-fluoro-7-nonenic acid;　2005/12
  ANNOUNCEMENT INFO.;　Pacifichem 2005(ハワイ)
  AUTHOR;　S. Osada, A. Soichi, K. Sakaguchi. C. W. Anderson, and H. Kodama
  
• Structures and Ion-Channel Activities of Cyclic Peptide Channel Nanotube;　2005/12
  ANNOUNCEMENT INFO.;　Pacifichem 2005(ハワイ)
  AUTHOR;　J. Taira, R. Hayashi, S. Osada, T. Ehara, and H. Kodama
  
• Synthesis and Elastase-Release Inhibition of Hymenamide B Analogs for Human Neutrophiles;　2005/12
  ANNOUNCEMENT INFO.;　Pacifichem 2005(ハワイ)
  AUTHOR;　Y. Shiki, J. Taira, A. Nakamura, S. Osada, and H. Kodama
  
• Synthesis and Antagonistic Activities of fMLP Analogs Containing Conformationaly　Restricted Amino Acid Derivatives;　2005/12
  ANNOUNCEMENT INFO.;　Pacifichem 2005(ハワイ)
  AUTHOR;　D. Sugiyama, R. Hayashi, M. Yoshiki, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Synthesis and Biological Properties of Transmembrane Peptides Derived from G Protein-Coupled Receptor;　2005/11
  ANNOUNCEMENT INFO.;　The 17th Japan-Korea Joint seminar for young Organic Chemists(長崎)
  AUTHOR;　R. Hayashi, D. Sugiyama, M. Yoshiki, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Effect of Anti-Parallel Dimerization for Ion Channel Properties of Helical Model Peptides;　2005/11
  ANNOUNCEMENT INFO.;　The 17th Japan-Korea Joint seminar for young Organic Chemists(長崎)
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, and H. Kodama
  
• Synthesis of Cyclic Peptides Derived from Marine Sponges;　2005/11
  ANNOUNCEMENT INFO.;　The 17th Japan-Korea Joint seminar for young Organic Chemists(長崎)
  AUTHOR;　Y. Shiki, J. Taira, A. Nakamura, S. Osada, and H. Kodama
  
• Structure-Activity Relationships of Human Formyl Peptide Receptor Antagonist Containing Cycropropane Derivatives;　2005/11
  ANNOUNCEMENT INFO.;　The 17th Japan-Korea Joint seminar for young Organic Chemists(長崎)
  AUTHOR;　D. Sugiyama, R. Hayashi, H. Kawasaki, H. Kodama, S. Osada, M. Zaitsu, and I. Fujita
  
• Synthesis of Transmembrane Peptides Derived from Human Formyl Peptide Receptor and Influence on Biological Activities of Human Neutrophils;　2005/10
  ANNOUNCEMENT INFO.;　第42回ペプチド討論会(大阪市)
  AUTHOR;　R. Hayashi, D. Sugiyama, M. Yoshiki, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Effect of Ring Size Alteration for Ion Channel Activities of Cyclic Peptides;　2005/10
  ANNOUNCEMENT INFO.;　第42回ペプチド討論会(大阪市)
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, T. Ehara, and H. Kodama
  
• Signal Transduction of Chemotactic Non-Formyl Peptide and Selective for Formyl Peptide Receptor;　2005/10
  ANNOUNCEMENT INFO.;　第42回ペプチド討論会(大阪市)
  AUTHOR;　M. Yoshiki, R. Hayashi, D. Sugiyama, S. Osada, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Ion Channel Activities Effected by Alteration about Hydrophobicities and Ring Size of Cyclic Peptides;　2005/10
  ANNOUNCEMENT INFO.;　第78回日本生化学会大会(神戸)
  AUTHOR;　J. Taira, S. Osada, M. Jelokhani-Niaraki, T. Ehara, and H. Kodama
  
• Enhancement of Chemotaxis for Human Neutrophils by Pretreatment with Porphyran;　2005/10
  ANNOUNCEMENT INFO.;　第78回日本生化学会大会(神戸)
  AUTHOR;　M. Yoshiki, K. Tsuge, T. Yoshimura, K. Koganemaru, I. Fujita, Y. Hamasaki, and H. Kodama
  
• Ion Channel Activities and Mechanisms of Ion Conduction about Cyclic Hexapeptides;　2005/06
  ANNOUNCEMENT INFO.;　19th American peptide symposium(San Diego, CA, U.S.A.)
  AUTHOR;　J. Taira, R. Hayashi, S. Osada, T. Ehara, and H. Kodama
  
• Synthesis and Biological Activities of Proline Rich Cyclic Heptapeptide Hymemanide B Analogs;　2005/06
  ANNOUNCEMENT INFO.;　19th American peptide symposium(San Diego, CA, U.S.A.)
  AUTHOR;　Y. Shiki, J. Taira, A. Nakamura, S. Osada, and H. Kodama
  
• Synthesis and Biological Activities of fMLP Analogs Containing 2,3-Cyclopropane Amino Acid Derivatives;　2005/06
  ANNOUNCEMENT INFO.;　19th American peptide symposium(San Diego, CA, U.S.A.)
  AUTHOR;　D. Sugiyama, R. Hayashi, H. Kawasaki, H. Kodama, S. Osada, M. Zaitsu, and I. Fujita
  
• Difluoromethylene group can act as a sulfur mimetic in methionine-containing chemotactic peptide;　2005/04
  ANNOUNCEMENT INFO.;　2nd Workshop on New Trends in Supramolecular Chemsitry(佐賀大学)
  AUTHOR;　S. Osada, H. Kawasaki, T. Ishimaru, M. Yoshiki, Y. Hamasaki, I. Fujita, and H Kodama
  
• Structure-Activity Relationships of Channel Forming Cyclopeptides;　2005/04
  ANNOUNCEMENT INFO.;　2nd Workshop on New Trends in Supramolecular Chemsitry(佐賀大学)
  AUTHOR;　J. Taira, R. Hayashi, S. Osada, T. Ehara, and H. Kodama
  
• Solid Phase Synthesis of Cyclic Peptides Containing Tyr Residue;　2004/11
  ANNOUNCEMENT INFO.;　16th Japan-Korea Joint Seminar for Young Organic Chemists(佐賀)
  AUTHOR;　Aya Nakamura, Satoshi Tatebe, Junichi Taira, Satoshi Osada, Hideki Ooba, Seiji Yasuda, Hiroaki Kodama
  
• Synthesis of Dimeric Tropoelastin Analogs, H-(Val-Pro-Gly-Val-Gly)n-Gly-Gly-Cys-NH2;　2004/11
  ANNOUNCEMENT INFO.;　16th Japan-Korea Joint Seminar for Young Organic Chemists(佐賀)
  AUTHOR;　Hiroaki Kodama, Satoshi Osada, Iori Maeda, Koji Okamoto
  
• Ion-channel properties of cyclic peptides;　2004/11
  ANNOUNCEMENT INFO.;　16th Japan-Korea Joint Seminar for Young Organic Chemists(佐賀)
  AUTHOR;　Junichi Taira, Ryo Hayashi, Masahiro Yoshiki, Satoshi Osada, Hiroaki Kodama
  
• Synthesis of helical peptides containing Met residres;　2004/11
  ANNOUNCEMENT INFO.;　16th Japan-Korea Joint Seminar for Young Organic Chemists(佐賀)
  AUTHOR;　Kanako Oku, Junichi Taira, Satoshi Osada, and Hiroaki Kodama
  
• Application of Oxidation-Resistant Methionine Mimic on Chemotactic Formyl-Methionyl Peptide;　2004/11
  ANNOUNCEMENT INFO.;　16th Japan-Korea Joint Seminar for Young Organic Chemists(佐賀)
  AUTHOR;　Satoshi Osada, Hiroshi Kawasaki, Takako Ishimaru, Masahiro Yoshiki, Yuhei Hamasaki, Ichiro Fujita, Hiroaki Kodama
  
• Ion-Channel Properties of Cyclic Hexapeptide cyclo(Pro-Xxx-Yyy)2;　2004/10
  ANNOUNCEMENT INFO.;　The First Asia-Pacific International Peptide Symposium and the 41st Japanese Peptide Symposium (APIPS/JPS) (福岡)
  AUTHOR;　Junichi Taira, Satoshi Osada, Ryo Hayashi, Masahiro Yoshiki, Satoshi Tatebe, Toshihisa Ueda, Tuguhisa Ehara, Hiroaki Kodama
  
• Solid-Phase Synthesis of Tyrosine-Containing Cyclic Peptides;　2004/10
  ANNOUNCEMENT INFO.;　The First Asia-Pacific International Peptide Symposium and the 41st Japanese Peptide Symposium (APIPS/JPS) (福岡)
  AUTHOR;　Aya Nakamura, Satoshi Tatebe, Junichi Taira, Satoshi Osada, Hideki Ooba, Seiji Yasuda, Hiroaki Kodama
  
• Synthesis and Biological Activity of Urease-related Peptides Generated from Helicobacter Pylori;　2004/10
  ANNOUNCEMENT INFO.;　The First Asia-Pacific International Peptide Symposium and the 41st Japanese Peptide Symposium (APIPS/JPS) (福岡)
  AUTHOR;　Masahiro Yoshiki, Keisuke Tsuge, Takashi Yoshimura, Kazuyoshi Koganemaru, Ichiro Fujita, Yuhei Hamasaki, Satoshi Osada, Hiroaki Kodama
  
• L-5,5-Difluoronorleucine as an Oxidation-Resistant Methionine Mimic: Facile Synthesis and Its Application on Chemotactic Peptide, fMLP;　2004/10
  ANNOUNCEMENT INFO.;　The First Asia-Pacific International Peptide Symposium and the 41st Japanese Peptide Symposium (APIPS/JPS) (福岡)
  AUTHOR;　Satoshi Osada, Hiroshi Kawasaki, Takako Ishimaru, Masahiro Yoshiki, Yuhei Hamasaki, Ichiro Fujita, Hiroaki Kodama
  
• Syhnthesis and biological activity of ion-channel peptides containing unusual amino acid;　2004/10
  ANNOUNCEMENT INFO.;　The 77th Annual Meeting of the Japanese Biochemical Society(Yokohama)
  AUTHOR;　Junichi Taira, Satoshi Osada, Tsuguhisa Ehara and Hiroaki Kodama
  
• Synthesis and properties of Aib-peptide containing Met and Met(O) residues;　2004/10
  ANNOUNCEMENT INFO.;　The 77th Annual Meeting of the Japanese Biochemical Society(Yokohama)
  AUTHOR;　Kanako Oku, Junichi Taira, Satoshi Osada, Fumio Kato and Hiroaki Kodama