Detailed Information

Research Field/Keywords for Research Field

• Infectious disease medicine

Education

• 1984/03, Graduated

Employment Experience

• 1984/06 - 1986/02
• 1986/03 - 1987/06
• 1987/06 - 1988/05
• 1988/06 - 1988/11
• 1988/12 - 1990/05
• 1990/06 - 1996/02 Research Associate
• 1996/03 - 1997/03
• 1997/04 - 1998/04 Research Associate
• 1998/05 - 2003/06 Lecturer
• 2003/07 - 2003/09 Associate Professor
• 2003/10 - 2007/03 Associate Professor, Medicine, Faculty of Medicine, Saga University
• 2005/04 - 2007/03 University Hospital, Faculty of Medicine, Saga University
• 2007/04 - 2009/03 University Hospital, Faculty of Medicine, Saga University
• 2007/04 - 2011/09 Associate Professor, Medicine, Faculty of Medicine, Saga University
• 2011/10 - 2011/09 Professor, Medicine, Faculty of Medicine, Saga University
• 2011/10 -  *  Professor, Medicine, Faculty of Medicine, Saga University
• 2013/04 -  *  University Hospital, Faculty of Medicine, Saga University

Field of Specialization

• Infectious disease medicine, Respiratory organ internal medicine, Laboratory medicine, Medical sociology, Foreign language education

Research Topics and Results

• Cognitive pitfall in diagnostic reasoning 2023/03
• On-site Gram staining that increases a post-test probability of an ominous infection: a case of necrotizing fasciitis caused by Vibrio vulnificus: a case report  2023/01
• Usefulness of the Legionella Score for differentiating from COVID-19 pneumonia to legionella pneumonia  2022/10
• 9.How to improve real-world speaking ability within conference and clinical settings 2022/07
• COVID19 fundamentals : What determines how it spreads? 2022/07
• Avoid Problems Before You Have to Solve Them: PCV13 2022/03
• Is trimethoprim/sulfamethoxazole-associated increase in serum creatinine a pseudo-elevation or true nephrotoxicity?  2021/08
• Impact of health policy on structural requisites for antimicrobial stewardship: A nationwide survey conducted in Japanese hospitals after enforcing the revised reimbursement system for antimicrobial stewardship programs  2021/01
• Treatment strategy for influenza viral infection in adolescent: What is the current adolescent treatment ? 2020/11
• Early prophylaxis of central venous catheter-related thrombosis using 1% chlorhexidine gluconate and chlorhexidine-gel-impregnated dressings: a retrospective cohort study 2020/09
• Distribution of Legionella species and serogroups in patients with culture-confirmed Legionella pneumonia 2020/03
• Essential human resources for antimicrobial stewardship teams in Japan: Estimates from a nationwide survey conducted by the Japanese Society of Chemotherapy 2019/09
• Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for clinical microbiology in 2014: General view of the pathogens' antibacterial susceptibility 2019/09
• Validation of a diagnostic score model for the prediction of Legionella pneumophila pneumonia 2019/06
• Clinical pharmacokinetic and pharmacodynamic analysis of daptomycin and the necessity of high-dose regimen in Japanese adult patients. 2019/06
• The first nationwide survey of antimicrobial stewardship programs conducted by the Japanese Society of Chemotherapy 2019/02
• Clinical utility of direct application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry and rapid disk diffusion test in presumptive antimicrobial therapy for bacteremia 2018
• How to Manage Antimicrobial resistance (Co-chair) 2018
• Ceftolozan /Tazobactam - Pneumonia 2018
• Infectious disease during hospitalization is the major causative factor for prolonged hospitalization: multivariate analysis of diagnosis procedure combination (DPC) data of 20,876 cases in Japan. 2016
• Clinical features of enterococcal bacteremia due to ampicillin-susceptible and ampicillin-resistant enterococci: An eight-year retrospective comparison study 2015
• Staphylococcus saprophyticus native valve endocarditis in a diabetic patient with neurogenic bladder: A case report 2015
• Prudent Antimirobial Use in Critically Ill Infections 2015
• Enterococcal endocarditis complicated with ruptured infected-intracranial aneurysm: With pharmacokinetic-pharmacodynamic documentation in proof of the successful antimicrobial treatment 2014
• 市中肺炎 2014
• Teaching and Learning Medicine in English 2014
• Dissociation of pharmacokinetic-pharmacodynamic success and clinical failure of Tazobactam/ Piperacillin in Escherichia coli bacteremia: A Case Report 2013
• Quality improvements in clinical practice of community-acquired bacteremia with marked reduction in mortality, A-10-year experience 2013
• A proposal for therapeutic drug monitoring (TDM)-guided therapy with beta-lactams. 2013
• Application of Beta-lactam Therapeutic Drug Monitoring in Clinical Practice Using HPLC. 2011
• Nationwid surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2008: 2011
• Aeromonas hydrophila菌血症を発症した肝硬変，糖尿病患者の一例 2010/11
• The importance of pharmacokinetic consultation of cefepime treatment for Pseudomonas aeruginosa bacteremia: a case report of severe thermal burn injury. 2010

Books

• Cognitive pitfall in diagnostic reasoning;　2023/03
  ANNOUNCEMENT INFO.;　Nihon Naika Gakkai Zasshi, 112, 3, 422-426
  AUTHOR;　Aoki Y
  
• Avoid Problems Before You Have to Solve Them: PCV13;　2022/03
  ANNOUNCEMENT INFO.;　Japanese Journal of Chemotherapy, 70, 2, 269
  AUTHOR;　Yosuke Aoki
  
• Treatment strategy for influenza viral infection in adolescent: What is the current adolescent treatment ?;　2020/11
  ANNOUNCEMENT INFO.;　Influenza : Advances in Diagnosis and Management (Respiratory Disease: Diagnostic Tools and Disease Managements), Chapter14, 137 - 146
  AUTHOR;　Yosuke Aoki
  

Original Articles

• Usefulness of the Legionella Score for differentiating from COVID-19 pneumonia to legionella pneumonia ;　2022/10
  ANNOUNCEMENT INFO.;　J Infect Chemother, 28, 10, 1353-1357
  AUTHOR;　*Naoyuki Miyashita, Futoshi Higa, Yosuke Aoki, Toshiaki Kikuchi, Masafumi Seki, Kazuhiro Tateda, Nobuko Maki, Kazuhiro Uchino, Hiroshi Kiyota, Akira Watanabe
  
• Is trimethoprim/sulfamethoxazole-associated increase in serum creatinine a pseudo-elevation or true nephrotoxicity? ;　2021/08
  ANNOUNCEMENT INFO.;　J Infect Chemother, 27, 8, 1193-1197
  AUTHOR;　Toshiharu Urakami, Yohei Hamada, Yusuke Oka, Mikinori Kannae, Tomohide Okinaka, Ayaka Sanada, Chisato Shimanoe, Yosuke Aoki
  
• Impact of health policy on structural requisites for antimicrobial stewardship: A nationwide survey conducted in Japanese hospitals after enforcing the revised reimbursement system for antimicrobial stewardship programs ;　2021/01
  ANNOUNCEMENT INFO.;　J Infect Chemother, 27, 1, 1-6
  AUTHOR;　*Masayuki Maeda, Yuichi Muraki, Tadashi Kosaka, Takehiro Yamada, Yosuke Aoki, Mitsuo Kaku, Masafumi Seki, Yoshinari Tanabe, Naohisa Fujita, Yoshihito Niki, Kunihiko Morita, Katsunori Yanagihara, Koichiro Yoshida, Tatsuya Kawaguchi
  
• Early prophylaxis of central venous catheter-related thrombosis using 1% chlorhexidine gluconate and chlorhexidine-gel-impregnated dressings: a retrospective cohort study;　2020/09
  ANNOUNCEMENT INFO.;　Sci Rep, 10, 1, 15952
  AUTHOR;　○Tomoko Yamashita, Ayako Takamori, Akira Nakagawachi, Yoshinori Tanigawa, Yohei Hamada, Yosuke Aoki, Yoshiro Sakaguchi
  
• Distribution of Legionella species and serogroups in patients with culture-confirmed Legionella pneumonia;　2020/03
  ANNOUNCEMENT INFO.;　J Infect Chemother, 26, 5, 411-417
  AUTHOR;　*Naoyuki Miyashita, Futoshi Higa, Yosuke Aoki, Toshiaki Kikuchi, Masafumi Seki, Kazuhiro Tateda, Nobuko Maki, Kazuhiro Uchino, Kazuhiko Ogasawara, Hiroshi Kiyota, Akira Watanabe
  
• Essential human resources for antimicrobial stewardship teams in Japan: Estimates from a nationwide survey conducted by the Japanese Society of Chemotherapy;　2019/09
  ANNOUNCEMENT INFO.;　J Infect Chemother, 25, 9, 653-656
  AUTHOR;　*Masayuki Maeda, Yuichi Muraki, Tadashi Kosaka, Takehiro Yamada, Yosuke Aoki, Mitsuo Kaku, Masafumi Seki, Yoshinari Tanabe, Naohisa Fujita, Yoshihito Niki, Kunihiko Morita, Katsunori Yanagihara, Koichiro Yoshida, Tatsuya Kawaguchi
  
• Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for clinical microbiology in 2014: General view of the pathogens' antibacterial susceptibility;　2019/09
  ANNOUNCEMENT INFO.;　J Infect Chemother, 25, 9, 657-668
  AUTHOR;　*Katsunori Yanagihara, Tetsuya Matsumoto, Nobuki Aoki, Junko Sato, Tomotaro Wakamura, Hiroshi Kiyota, Kazuhiro Tateda, Hideaki Hanaki, Yoshinobu Ohsaki, Satoru Fujiuchi, Manabu Takahashi, Yuji Akiba, Shingo Masunaga, Kenichi Takeuchi, Hiroaki Takeda, Makoto Miki, Toshio Kumagai, Hiroshi Takahashi, Mutsuko Utagawa, Hajime Nishiya, Sayoko Kawakami, Shinobu Ishigaki, Nobuyuki Kobayasi, Jin Takasaki, Kazuhisa Mezaki, Satoshi Iwata, Yasuhiro Katouno, Rika Inose, Yoshihito Niki, Akihiko Kawana, Yuji Fujikura, Makoto Kudo, Tomo Hirano, Masaki Yamamoto, Naoki Miyazawa, Hiroki Tsukada, Sakura Aso, Yoshihiro Yamamoto, Yoshitsugu Iinuma, Hiroshige Mikamo, Yuka Yamagishi, Atsushi Nakamura, Minoru Ohashi, Atsushi Kawabata, Yoshiko Sugaki, Masafumi Seki, Shigeto Hamaguchi, Masahiro Toyokawa, Hiroshi Kakeya, Yasunori Fujikawa, Noriko Mitsuno, Akira Ukimura, Takayuki Miyara, Michio Hayasi, Keiichi Mikasa, Kei Kasahara, Akira Koizumi, Nobuyoshi Korohasi, Takashi Matumoto, Yutaka Yosimura, Yuichi Katanami, Yoshio Takesue, Yasunao Wada, Keisuke Sugimoto, Tsuyoshi Yamamoto, Masao Kuwabara, Masao Doi, Satomi Simizu, Hirokazu Tokuyasu, Satoshi Hino, Kiyoshi Negayama, Hiroshi Mukae, Toshinori Kawanami, Kazuhiro Yatera, Masaki Fujita, Junichi Kadota, Kazufumi Hiramatsu, Yosuke Aoki, Hiroki Magarifuchi, Megumi Oho, Yoshitomo Morinaga, Moritaka Suga, Hiroyuki Muranaka, Jiro Fujita, Futoshi Higa, Masao Tateyama
  
• Validation of a diagnostic score model for the prediction of Legionella pneumophila pneumonia;　2019/06
  ANNOUNCEMENT INFO.;　J Infect Chemother, 25, 6, 407-412
  AUTHOR;　*Naoyuki Miyashita, Nobuyuki Horita, Futoshi Higa, Yosuke Aoki, Toshiaki Kikuchi, Masafumi Seki, Kazuhiro Tateda, Nobuko Maki, Kazuhiro Uchino, Kazuhiko Ogasawara, Hiroshi Kiyota, Akira Watanabe
  
• Clinical pharmacokinetic and pharmacodynamic analysis of daptomycin and the necessity of high-dose regimen in Japanese adult patients.;　2019/06
  ANNOUNCEMENT INFO.;　J Infect Chemother. , 25, 6, 437-443
  AUTHOR;　Urakami T, Hamada Y, Oka Y, Okinaka T, Yamakuchi H, Magarifuchi H, Aoki Y
  
• The first nationwide survey of antimicrobial stewardship programs conducted by the Japanese Society of Chemotherapy;　2019/02
  ANNOUNCEMENT INFO.;　J Infect Chemother, 25, 2, 83-88
  AUTHOR;　*Masayuki Maeda, Yuichi Muraki, Tadashi Kosaka, Takehiro Yamada, Yosuke Aoki, Mitsuo Kaku, Tatsuya Kawaguchi, Masafumi Seki, Yoshinari Tanabe, Naohisa Fujita, Kunihiko Morita, Katsunori Yanagihara, Koichiro Yoshida, Yoshihito Niki
  
• Clinical utility of direct application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry and rapid disk diffusion test in presumptive antimicrobial therapy for bacteremia;　2018
  ANNOUNCEMENT INFO.;　J Infect Chemother. , 24, 11, 881-886
  AUTHOR;　Magarihuchi H, Hamada Y, Oho M, Kusaba K, Urakami T, Aoki Y.
  
• Infectious disease during hospitalization is the major causative factor for prolonged hospitalization: multivariate analysis of diagnosis procedure combination (DPC) data of 20,876 cases in Japan.;　2016
  ANNOUNCEMENT INFO.;　J Clin Biochem Nutr., 59, 1, 49-52
  AUTHOR;　〇Fujii S, Hara M, Nonaka S, Ishikawa S, Aoki Y, Anzai K, Morita S, Fujimoto K, Mawatari M
  
• Clinical features of enterococcal bacteremia due to ampicillin-susceptible and ampicillin-resistant enterococci: An eight-year retrospective comparison study;　2015
  ANNOUNCEMENT INFO.;　J Infect Chemother., 21, 7, p.p.527-30
  AUTHOR;　Yohei Hamada, Hiroki Magarifuchi, Megumi Oho, Zenzo Nagasawa, Mami Fukuoka, Hiroki Yamakuchi, Toshiharu Urakami, Yosuke Aoki
  
• Enterococcal endocarditis complicated with ruptured infected-intracranial aneurysm: With pharmacokinetic-pharmacodynamic documentation in proof of the successful antimicrobial treatment;　2014
  ANNOUNCEMENT INFO.;　J Infect Chemother. , 20, 12, 810-3
  AUTHOR;　Urakami T, Hamada Y, i Magarihuchi H, Yamakuchi H, Aoki Y
  
• Application of Beta-lactam Therapeutic Drug Monitoring in Clinical Practice Using HPLC.;　2011
  ANNOUNCEMENT INFO.;　Journal of Bioanalysis and Biomedicine (doi: 10.4172/1948-593X. S3-011)
  AUTHOR;　Toshiharu Urakami, Yosuke Aoki, Mami Fukuoka, Hiroki Magarifuchi, Masaki Nagata, Znzo Nagasawa, Yukitaka Nakano, Hiroshi Fujito
  
• Nationwid surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2008:;　2011
  ANNOUNCEMENT INFO.;　J Infect Chemother　, 17, 4, 510-523
  AUTHOR;　Yoshihito Niki, et al 63 authora including Yosuke Aoki.
  
• Nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2007: general view of the pathogens' antibacterial susceptibility.;　2009
  ANNOUNCEMENT INFO.;　J Infect Chemother, 15, 156 - 167., 15, 156-167
  AUTHOR;　○Japanese Society for Chemotherapy (101 authors including Aoki Y, Nagasawa Z)
  
• Quantitative microarray-based DNA-DNA hybridization assay for measuring genetic distances among bacterial species and its application to the identification of family Enterobacteriaceae;　2005
  ANNOUNCEMENT INFO.;　 Microbiol. Immunol, 49
  AUTHOR;　Amamo A, 他10名
  
• Detection method of β-lactam antibiotic induced vancomycin-resistant MRSA and combined effects of antibiotics against MRSA;　2003/10
  ANNOUNCEMENT INFO.;　, 51, 10, 631-637
  AUTHOR;　
  
• Sensitivity of gram-positive cocci to antibacterial agents, with special reference to linezolid;　2003/09
  ANNOUNCEMENT INFO.;　, 51, 9, 574-578
  AUTHOR;　
  
• Dexamethazone accelerates catabolism of leukotriene C4 in bronchial epithelial cells.;　2003
  ANNOUNCEMENT INFO.;　Eur. Respir. J., 22, 35-42
  AUTHOR;　Zaitsu M, HamasakiM,Tsuji K, Matsuo M, Fujita I,Aoki Y,Ishii E,Kohashi O
  

Material, Commentary, Editorials, Research Report, A Comprehensive Journal Articles

• On-site Gram staining that increases a post-test probability of an ominous infection: a case of necrotizing fasciitis caused by Vibrio vulnificus: a case report ;　2023/01
  ANNOUNCEMENT INFO.;　J Med Case Rep, 17, 1, 9
  AUTHOR;　*Kannae M, Oka Y, Hamada Y, Urakami T, Aoki Y
  
• Staphylococcus saprophyticus native valve endocarditis in a diabetic patient with neurogenic bladder: A case report;　2015
  ANNOUNCEMENT INFO.;　J Infect Chemother., 21, 9, p.p.695-9
  AUTHOR;　Hiroki Magarifuchi, Koji Kusaba,Hiroki Yamakuchi, Yohei Hamada, Toshiharu Urakami, Yosuke Aoki
  
• The importance of pharmacokinetic consultation of cefepime treatment for Pseudomonas aeruginosa bacteremia: a case report of severe thermal burn injury.;　2010
  ANNOUNCEMENT INFO.;　Journal of Infection and Chemotherapy　DOI 10.1007/s10156-010-0119-8
  AUTHOR;　Aoki Y, Urakami T, Magarifuchi H, Nagasawa Z,Nagata M, Fukuoka K.
  

General Lectures

• 9.How to improve real-world speaking ability within conference and clinical settings;　2022/07
  ANNOUNCEMENT INFO.;　The 25th JASMEE Academic Meeting, 2022, 7,16-17
  AUTHOR;　○Maiko Sakamoto Pomeroy, Yosuke Aoki
  
• COVID19 fundamentals : What determines how it spreads?;　2022/07
  ANNOUNCEMENT INFO.;　The 25th JASMEE Academic Meeting, 2022, 7,16-17
  AUTHOR;　Yosuke Aoki
  
• How to Manage Antimicrobial resistance (Co-chair);　2018
  ANNOUNCEMENT INFO.;　18th International Congress on Infectious Diseases, 2018/3/1 - 4
  AUTHOR;　Yosuke Aoki
  
• Ceftolozan /Tazobactam - Pneumonia;　2018
  ANNOUNCEMENT INFO.;　Global Gram-negative Anti-Infective Board (Zurich), 2018/9/21
  AUTHOR;　Yosuke Aoki
  
• Teaching and Learning Medicine in English;　2014
  ANNOUNCEMENT INFO.;　The 17th JASMEE Academic Meeting, 2014.7.19-20
  AUTHOR;　Aoki Y
  
• Quality improvements in clinical practice of community-acquired bacteremia with marked reduction in mortality, A-10-year experience;　2013
  ANNOUNCEMENT INFO.;　28th International Congress of Chemotherapy and Infection, 2013年6月5-8日
  AUTHOR;　Aoki Y, Hamada Y, Magarihuchi H, Urakami T
  
• A proposal for therapeutic drug monitoring (TDM)-guided therapy with beta-lactams.;　2013
  ANNOUNCEMENT INFO.;　28th International Congress of Chemotherapy and Infection, 2013年6月5-8日
  AUTHOR;　Urakami T, Hamada Y, Magarihuchi H, Yamakuchi H, Fukuoka M, Aoki Y.
  
• Aeromonas hydrophila菌血症を発症した肝硬変，糖尿病患者の一例;　2010/11
  ANNOUNCEMENT INFO.;　
  AUTHOR;　
  

Review Articles

• 市中肺炎;　2014
  ANNOUNCEMENT INFO.;　, 102, 213 - 222.
  AUTHOR;　
  
• Dissociation of pharmacokinetic-pharmacodynamic success and clinical failure of Tazobactam/ Piperacillin in Escherichia coli bacteremia: A Case Report;　2013
  ANNOUNCEMENT INFO.;　J Med Case, 4, 12, 820-824
  AUTHOR;　Magarifuchi H, Urakami T, Yamakuchi H, Hamada Y, Aoki Y.
  

Invited Lecture, Special Lecture

• Prudent Antimirobial Use in Critically Ill Infections;　2015
  ANNOUNCEMENT INFO.;　S Class Plus Symposium, 2015/5/9
  AUTHOR;　Yosuke Aoki
  
• Problem-based Learning: A Six-years’ experience in Saga Medical School (Invited lecture);　2006/01
  ANNOUNCEMENT INFO.;　
  AUTHOR;　Yosuke Aoki