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Estimating rotavirus vaccine effectiveness in Japan using a screening method

発表形態:
原著論文
主要業績:
主要業績
単著・共著:
共著
発表年月:
2016年05月
DOI:
10.1080/21645515.2015.1121337
会議属性:
指定なし
査読:
有り
リンク情報:

日本語フィールド

著者:
Araki K, Hara M, Sakanishi Y, Shimanoe C, Nishida Y, Matsuo M, Tanaka K
題名:
Estimating rotavirus vaccine effectiveness in Japan using a screening method
発表情報:
Human Vaccines and Immunotherapeutics 巻: 12 号: 5 ページ: 1244 - 1249
キーワード:
概要:
© 2016 The Author(s). Published with license by Taylor & Francis abstract: Rotavirus gastroenteritis is a highly contagious, acute viral disease that imposes a significant health burden worldwide. In Japan, rotavirus vaccines have been commercially available since 2011 for voluntary vaccination, but vaccine coverage and effectiveness have not been evaluated. In the absence of a vaccination registry in Japan, vaccination coverage in the general population was estimated according to the number of vaccines supplied by the manufacturer, the number of children who received financial support for vaccination, and the size of the target population. Patients with rotavirus gastroenteritis were identified by reviewing the medical records of all children who consulted 6 major hospitals in Saga Prefecture with gastroenteritis symptoms. Vaccination status among these patients was investigated by reviewing their medical records or interviewing their guardians by telephone. Vaccine effectiveness was determined using a screening method. Vaccination coverage increased with time, and it was 2-times higher in municipalities where the vaccination fee was supported. In the 2012/13 season, vaccination coverage in Saga Prefecture was 14.9% whereas the proportion of patients vaccinated was 5.1% among those with clinically diagnosed rotavirus gastroenteritis and 1.9% among those hospitalized for rotavirus gastroenteritis. Thus, vaccine effectiveness was estimated as 69.5% and 88.8%, respectively. This is the first study to evaluate rotavirus vaccination coverage and effectiveness in Japan since vaccination began.
抄録:

英語フィールド

Author:
Araki K, Hara M, Sakanishi Y, Shimanoe C, Nishida Y, Matsuo M, Tanaka K
Title:
Estimating rotavirus vaccine effectiveness in Japan using a screening method
Announcement information:
Human Vaccines and Immunotherapeutics Vol: 12 Issue: 5 Page: 1244 - 1249
An abstract:
© 2016 The Author(s). Published with license by Taylor & Francis abstract: Rotavirus gastroenteritis is a highly contagious, acute viral disease that imposes a significant health burden worldwide. In Japan, rotavirus vaccines have been commercially available since 2011 for voluntary vaccination, but vaccine coverage and effectiveness have not been evaluated. In the absence of a vaccination registry in Japan, vaccination coverage in the general population was estimated according to the number of vaccines supplied by the manufacturer, the number of children who received financial support for vaccination, and the size of the target population. Patients with rotavirus gastroenteritis were identified by reviewing the medical records of all children who consulted 6 major hospitals in Saga Prefecture with gastroenteritis symptoms. Vaccination status among these patients was investigated by reviewing their medical records or interviewing their guardians by telephone. Vaccine effectiveness was determined using a screening method. Vaccination coverage increased with time, and it was 2-times higher in municipalities where the vaccination fee was supported. In the 2012/13 season, vaccination coverage in Saga Prefecture was 14.9% whereas the proportion of patients vaccinated was 5.1% among those with clinically diagnosed rotavirus gastroenteritis and 1.9% among those hospitalized for rotavirus gastroenteritis. Thus, vaccine effectiveness was estimated as 69.5% and 88.8%, respectively. This is the first study to evaluate rotavirus vaccination coverage and effectiveness in Japan since vaccination began.


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