日本語フィールド
著者：Makita, Yoshimasa; Kawaguchi, Shin Ichi; Fujiwara, Shin Ichi題名：CHARACTERIZATION AND ANTITUMOR ACTIVITY OF FURAZANO[3,4-g]PTERIDINE-2,4(1H,3H)-DIONE発表情報：Heterocycles 巻: 104 号: 5 ページ: - キーワード：概要：Alloxazine derivatives exhibit a wide variety of properties imparted by their tautomerization to isoalloxazine and the presence of similar H-bonding to uracil. Herein, we characterized the structure and properties of furazano[3,4-g]pteridine-2,4(1H,3H)-dione (1) by X-ray crystal structure analysis and evaluated its antitumor activity. The IC50 value of 1 was 172 μM, as determined using HeLa cells.抄録：英語フィールド
Author：Makita, Yoshimasa; Kawaguchi, Shin Ichi; Fujiwara, Shin IchiTitle：CHARACTERIZATION AND ANTITUMOR ACTIVITY OF FURAZANO[3,4-g]PTERIDINE-2,4(1H,3H)-DIONEAnnouncement information:Heterocycles Vol: 104 Issue: 5 Page: - An abstract：Alloxazine derivatives exhibit a wide variety of properties imparted by their tautomerization to isoalloxazine and the presence of similar H-bonding to uracil. Herein, we characterized the structure and properties of furazano[3,4-g]pteridine-2,4(1H,3H)-dione (1) by X-ray crystal structure analysis and evaluated its antitumor activity. The IC50 value of 1 was 172 μM, as determined using HeLa cells.