日本語フィールド
著者：Higashimae, Shinya; Kurata, Daichi; Kawaguchi, Shin Ichi; Kodama, Shintaro; Sonoda, Motohiro; Nomoto, Akihiro; Ogawa, Akiya題名：Palladium-Catalyzed Cyanothiolation of Internal Alkynes Using Organic Disulfides and tert-Butyl Isocyanide発表情報：Journal of Organic Chemistry 巻: 83 号: 9 ページ: 5267 - 5273キーワード：概要：© 2018 American Chemical Society. Despite the availability of selective synthetic approaches to multifunctionalized substituted olefins, the cyanothiolation of internal alkynes has been much less explored. Herein, we show that nonactivated internal alkynes can be successfully cyanothiolated with diaryl disulfides and tert-butyl isocyanide in the presence of a Pd catalyst (e.g., Pd(PPh3)4) with the release of isobutene and arenethiol to afford β-thiolated alkenyl cyanides in yields of 34-89%.抄録：英語フィールド
Author：Higashimae, Shinya; Kurata, Daichi; Kawaguchi, Shin Ichi; Kodama, Shintaro; Sonoda, Motohiro; Nomoto, Akihiro; Ogawa, AkiyaTitle：Palladium-Catalyzed Cyanothiolation of Internal Alkynes Using Organic Disulfides and tert-Butyl IsocyanideAnnouncement information:Journal of Organic Chemistry Vol: 83 Issue: 9 Page: 5267 - 5273An abstract：© 2018 American Chemical Society. Despite the availability of selective synthetic approaches to multifunctionalized substituted olefins, the cyanothiolation of internal alkynes has been much less explored. Herein, we show that nonactivated internal alkynes can be successfully cyanothiolated with diaryl disulfides and tert-butyl isocyanide in the presence of a Pd catalyst (e.g., Pd(PPh3)4) with the release of isobutene and arenethiol to afford β-thiolated alkenyl cyanides in yields of 34-89%.