日本語フィールド
著者:Yamaguchi, Kotaro; Kawaguchi, Shin ichi; Sonoda, Motohiro; Tanimori, Shinji; Ogawa, Akiya題名:Copper-catalyzed tandem reaction directed toward synthesis of 2,2-disubstituted quinazolinones from vinyl halides and 2-aminobenzamides発表情報:Tetrahedron Letters 巻: 58 号: 43 ページ: 40434047キーワード:概要:© 2017 Elsevier Ltd A copper-catalyzed tandem reaction with vinyl halides and 2-aminobenzamides has been developed. In this synthetic route, cross-coupling reaction of the amide moiety with vinyl halides initially progresses, followed by hydroamination, to provide 2,2-disubstituted quinazolinone derivatives. Moreover, the tandem reaction is used in a one-pot synthesis beginning with alkyne hydroiodination by PPh 3 , I 2 , and H 2 O.抄録:英語フィールド
Author:Yamaguchi, Kotaro; Kawaguchi, Shin ichi; Sonoda, Motohiro; Tanimori, Shinji; Ogawa, AkiyaTitle:Copper-catalyzed tandem reaction directed toward synthesis of 2,2-disubstituted quinazolinones from vinyl halides and 2-aminobenzamidesAnnouncement information:Tetrahedron Letters Vol: 58 Issue: 43 Page: 40434047An abstract:© 2017 Elsevier Ltd A copper-catalyzed tandem reaction with vinyl halides and 2-aminobenzamides has been developed. In this synthetic route, cross-coupling reaction of the amide moiety with vinyl halides initially progresses, followed by hydroamination, to provide 2,2-disubstituted quinazolinone derivatives. Moreover, the tandem reaction is used in a one-pot synthesis beginning with alkyne hydroiodination by PPh 3 , I 2 , and H 2 O.