日本語フィールド
著者：○Ishibashi Y, Haraguchi R, Aoki S, Oishi Y, Narita T題名：Effect of UV Irradiation of Pre-Gel Solutions on the Formation of Collagen Gel Tubes 発表情報：Gels 巻: 9 号: 6 ページ: 458キーワード：collagen; hollow structure; photo-cross-linking; pre-gel solution; ultraviolet light modification概要：Hollow collagen gels are promising materials for drug/cell delivery systems to promote tissue regeneration because they may be able to function as carriers for these types of loads. Controlling the cavity size and swelling suppression is essential to expand the applications and improve the usability of such gel-like systems. We investigated the effects of UV-treated collagen solutions as a pre-gel aqueous mixture on the formation and properties of the hollow collagen gels in terms of their preparation range limits, morphology, and swelling ratio. The UV treatment thickened the pre-gel solutions, which allowed hollowing at lower collagen concentrations. This treatment also prevents the over-swelling of the hollow collagen rods in PBS buffer solutions. The UV-treated collagen solutions provided a large lumen space in the prepared collagen hollow fiber rods with a limited swelling ratio, allowing vascular endothelial cells and ectodermal cells to be cultured separately in the outer and inner lumen. 抄録：英語フィールド
Author：○Ishibashi Y, Haraguchi R, Aoki S, Oishi Y, Narita TTitle：Effect of UV Irradiation of Pre-Gel Solutions on the Formation of Collagen Gel Tubes Announcement information:Gels Vol: 9 Issue: 6 Page: 458Keyword：collagen; hollow structure; photo-cross-linking; pre-gel solution; ultraviolet light modificationAn abstract：Hollow collagen gels are promising materials for drug/cell delivery systems to promote tissue regeneration because they may be able to function as carriers for these types of loads. Controlling the cavity size and swelling suppression is essential to expand the applications and improve the usability of such gel-like systems. We investigated the effects of UV-treated collagen solutions as a pre-gel aqueous mixture on the formation and properties of the hollow collagen gels in terms of their preparation range limits, morphology, and swelling ratio. The UV treatment thickened the pre-gel solutions, which allowed hollowing at lower collagen concentrations. This treatment also prevents the over-swelling of the hollow collagen rods in PBS buffer solutions. The UV-treated collagen solutions provided a large lumen space in the prepared collagen hollow fiber rods with a limited swelling ratio, allowing vascular endothelial cells and ectodermal cells to be cultured separately in the outer and inner lumen. 