日本語フィールド
著者：○Hironobu Takedomi, Yasuhisa Sakata, Michito Tomonaga, Naomi Naruse, Takahiro Yukimoto, Takashi Akutagawa, Nanae Tsuruoka, Ryo Shimoda, Shinichi Kido, Motohiro Esaki題名：Collagenous Colitis Possibly Associated with Dipeptidyl Peptidase-4 Inhibitor発表情報：Intern Med 巻: 61 号: 18 ページ: 2731-2734キーワード：chronic diarrhea; collagenous colitis; dipeptidyl peptidase-4 inhibitor; endoscopic finding; microscopic colitis概要：A 60-year-old man with type 2 diabetes mellitus treated with a dipeptidyl peptidase-4 (DPP-4) inhibitor was referred to our hospital because of his refractory watery diarrhea. Ileocolonoscopy revealed increased capillary growth, fine granular mucosa, and longitudinal mucosal tears mainly in the left side of the colon. A bioptic examination revealed thickened subepithelial collagen bands, thus confirming the diagnosis of collagenous colitis. Systemic steroid therapy was initiated, but his symptoms recurred when tapering the steroid. However, withdrawal of the DPP-4 inhibitor was successful even after the cessation of steroid therapy. We therefore considered his collagenous colitis to have been caused by the DPP-4 inhibitor. 抄録：英語フィールド
Author：○Hironobu Takedomi, Yasuhisa Sakata, Michito Tomonaga, Naomi Naruse, Takahiro Yukimoto, Takashi Akutagawa, Nanae Tsuruoka, Ryo Shimoda, Shinichi Kido, Motohiro EsakiTitle：Collagenous Colitis Possibly Associated with Dipeptidyl Peptidase-4 InhibitorAnnouncement information:Intern Med Vol: 61 Issue: 18 Page: 2731-2734Keyword：chronic diarrhea; collagenous colitis; dipeptidyl peptidase-4 inhibitor; endoscopic finding; microscopic colitisAn abstract：A 60-year-old man with type 2 diabetes mellitus treated with a dipeptidyl peptidase-4 (DPP-4) inhibitor was referred to our hospital because of his refractory watery diarrhea. Ileocolonoscopy revealed increased capillary growth, fine granular mucosa, and longitudinal mucosal tears mainly in the left side of the colon. A bioptic examination revealed thickened subepithelial collagen bands, thus confirming the diagnosis of collagenous colitis. Systemic steroid therapy was initiated, but his symptoms recurred when tapering the steroid. However, withdrawal of the DPP-4 inhibitor was successful even after the cessation of steroid therapy. We therefore considered his collagenous colitis to have been caused by the DPP-4 inhibitor. 