日本語フィールド
著者:○Shun Fujimoto, Nanae Tsuruoka, Motohiro Esaki, Ayako Takamori, Yasuhisa Sakata, Ryo Shimoda, Takashi Akutagawa, Koichi Node, Keizo Anzai, Nobuyuki Sugisaki, Ryuichi Iwakiri, Kuniaki Takagi, Kohei Yamanouchi, Kazuma Fujimoto題名:Decline incidence in upper gastrointestinal bleeding in several recent years: data of the Japan claims database of 13 million accumulated patients 発表情報:J Clin Biochem Nutr 巻: 68 号: 1 ページ: 95-100キーワード:JMDC; antithrombotic; gastroesophageal reflux disease; peptic ulcer; proton pump inhibitor概要:This study was to examine the recent trends in upper gastrointestinal bleeding in Japan using a large-scale real-world database. The incidence of upper gastrointestinal bleeding was evaluated in the Japan Medical Data Center claims database of 13,019,713 patients aged 20 to 74 years with traceability for 3 months from 2009 to 2014. The incidence was compared with peptic ulcers and gastroesophageal reflux disease. The prescription of medications was also evaluated. The incidence of bleeding was 0.137%, 0.121%, 0.113%, 0.106%, 0.099%, and 0.105% during 2009 to 2014 with a time-dependent decline (p<0.001). Peptic ulcers (>10 times higher than the incidence of bleeding) decreased with time (p<0.001), whereas gastroesophageal reflux disease increased (p = 0.006). Upper gastrointestinal bleeding was higher in male patients and older patients (60-74 years old) (p<0.001 respectively). The prescription rate of antithrombotic medications and proton pump inhibitors increased from 2009 to 2014 (p<0.001 respectively). The incidence of upper gastrointestinal bleeding decreased from 2009 to 2014 in this relatively large-scale real-world database in Japan, concomitant with the decrease in peptic ulcers. The decreased incidence might have been due to changes in the disease structure and therapeutic strategies over time. 抄録:英語フィールド
Author:○Shun Fujimoto, Nanae Tsuruoka, Motohiro Esaki, Ayako Takamori, Yasuhisa Sakata, Ryo Shimoda, Takashi Akutagawa, Koichi Node, Keizo Anzai, Nobuyuki Sugisaki, Ryuichi Iwakiri, Kuniaki Takagi, Kohei Yamanouchi, Kazuma FujimotoTitle:Decline incidence in upper gastrointestinal bleeding in several recent years: data of the Japan claims database of 13 million accumulated patients Announcement information:J Clin Biochem Nutr Vol: 68 Issue: 1 Page: 95-100Keyword:JMDC; antithrombotic; gastroesophageal reflux disease; peptic ulcer; proton pump inhibitorAn abstract:This study was to examine the recent trends in upper gastrointestinal bleeding in Japan using a large-scale real-world database. The incidence of upper gastrointestinal bleeding was evaluated in the Japan Medical Data Center claims database of 13,019,713 patients aged 20 to 74 years with traceability for 3 months from 2009 to 2014. The incidence was compared with peptic ulcers and gastroesophageal reflux disease. The prescription of medications was also evaluated. The incidence of bleeding was 0.137%, 0.121%, 0.113%, 0.106%, 0.099%, and 0.105% during 2009 to 2014 with a time-dependent decline (p<0.001). Peptic ulcers (>10 times higher than the incidence of bleeding) decreased with time (p<0.001), whereas gastroesophageal reflux disease increased (p = 0.006). Upper gastrointestinal bleeding was higher in male patients and older patients (60-74 years old) (p<0.001 respectively). The prescription rate of antithrombotic medications and proton pump inhibitors increased from 2009 to 2014 (p<0.001 respectively). The incidence of upper gastrointestinal bleeding decreased from 2009 to 2014 in this relatively large-scale real-world database in Japan, concomitant with the decrease in peptic ulcers. The decreased incidence might have been due to changes in the disease structure and therapeutic strategies over time.