日本語フィールド
著者：石田 知也, 峯崎 晃充, 嶋崎 絵里子, 山内 盛泰, 島津 倫太郎, 倉富 勇一郎題名：原著 浸潤能評価に基づく早期舌癌の頸部郭清方針に関する検討発表情報：頭頸部癌 巻: 47 号: 3 ページ: 295-302キーワード：早期舌癌, 浸潤能評価, YK分類, 後発頸部転移, 頸部郭清概要：初回治療として切除手術を施行し経過観察した45例の早期舌癌（pT1, 2N0，UICC第7版）について，第8版によるpT再分類とYK分類による浸潤能評価を行い，後発頸部転移と生存率との関連を検討した。pT1/2/3（第8版）は17/20/8例で，YK-1, 2/3/4C, 4Dは10/18/17例であった。pT1/2/3の後発転移率，5年疾患特異的生存率はそれぞれ29/45/63％，88/85/63％で，YK-1, 2/3/4C, 4Dでは10/39/65％，100/100/53％であり，pT分類よりもYK分類の方がより強く予後に関連していた。低?中等度浸潤性のYK-1-3型の腫瘍は後発転移後の頸部郭清で全例が制御されており，これらの腫瘍では経過観察の方針が妥当と思われた。YK-4C, 4Dの高度浸潤型では経過観察では予後は不良であり，切除後早期の頸部郭清追加などの治療強度の拡大が必要と思われた。 抄録：英語フィールド
Author：Tomoya Ishida, Akimichi Minesaki, Eriko Shimazaki, Moriyasu Yamauchi, Rintaro Shimazu, Yuichiro KuratomiTitle：Strategy of neck dissection for early tongue cancer based on tumor invasion potentialAnnouncement information:Toukeibu Gan Vol: 47 Issue: 3 Page: 295-302Keyword：Early tongue cancer, Invasion potential, Neck dissection, Late cervical metastasis, Survival rateAn abstract：pT re-classification according to the UICC, 8th edition and evaluation of tumor invasion potential by the Yamamoto-Kohama （YK） classification were performed for 45 patients with pT1, 2N0 oral tongue cancers （UICC, 7th edition） who had undergone surgical resection as initial treatment followed by observation. Association between the two factors and late cervical metastases and survival rates were analyzed. The number of patients with pT1/2/3 （UICC, 8th edition） and YK-1, 2/3/4C, 4D was 17/20/8 and 10/18/17, respectively. The late cervical metastasis rate and 5-year disease-specific survival rate for pT1/2/3 were 29/45/63％ and 88/85/63％, and for YK-1, 2/3/4C, 4D were 10/39/65％ and 100/100/53％, respectively. Tumor invasion potential was more strongly associated with prognosis than pT classification （8th edition）. All of the low to moderately invasive YK-1-3 tumors were controlled by neck dissection after the appearance of late cervical metastasis, and therefore, the observation strategy seems to be appropriate for these tumors. In contrast, the highly invasive YK-4C, 4D tumors presented poor control rates by the observation strategy, and therefore, might need more intensive treatments such as additional neck dissection following primary tumor resection before late cervical metastasis appears. 