日本語フィールド
著者：J. Taira, M. Shibue, S. Osada, H. Kodama題名：Peptaibol Derived Helix-Kink Motif Facilitates Channel Forming of the Artificial α-Aminoisobutyric Acid Rich Helices発表情報：Int. J. Petp. Res. Ther. 巻: 16 ページ: 277-282キーワード：Aib, Helix-kink motif, Circular dichroism, Ion channel peptide, Peptaibol概要：抄録：Characteristic motifs have been identified in natural channel forming peptides though critical roles of such motifs are not well understood. In this paper, the helix-kink motif found in peptaibols was embedded into
the a-aminoisobutyric acid (Aib) rich template to explore its roles in peptide structure and ion channel functions. According to circular dichroism studies and single channel measurements, the motif reduced helical contents of peptide whereas ion channel forming was facilitated and conductance value was increased.英語フィールド
Author：J. Taira, M. Shibue, S. Osada, H. KodamaTitle：Peptaibol Derived Helix-Kink Motif Facilitates Channel Forming of the Artificial α-Aminoisobutyric Acid Rich HelicesAnnouncement information:Int. J. Petp. Res. Ther. Vol: 16 Page: 277-282Keyword：Aib, Helix-kink motif, Circular dichroism, Ion channel peptide, PeptaibolAn abstract：Characteristic motifs have been identified in natural channel forming peptides though critical roles of such motifs are not well understood. In this paper, the helix-kink motif found in peptaibols was embedded into
the a-aminoisobutyric acid (Aib) rich template to explore its roles in peptide structure and ion channel functions. According to circular dichroism studies and single channel measurements, the motif reduced helical contents of peptide whereas ion channel forming was facilitated and conductance value was increased.