日本語フィールド
著者：*Ippei Shimoshikiryo, Rie Ibusuki, Keiichi Shimatani, Daisaku Nishimoto, Toshiro Takezaki, Yuichiro Nishida, Chisato Shimanoe, Asahi Hishida, Takashi Tamura, Rieko Okada, Yoko Kubo, Etsuko Ozaki, Daisuke Matsui, Sadao Suzuki, Hiroko Nakagawa-Senda, Kiyonori Kuriki, Yoshikuni Kita, Naoyuki Takashima, Kokichi Arisawa, Hirokazu Uemura, Hiroaki Ikezaki, Norihiro Furusyo, Isao Oze, Yuriko N Koyanagi, Haruo Mikami, Yohko Nakamura, Mariko Naito, Kenji Wakai, J-MICC Study Group題名：Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction: A cross-sectional study from the Japan Multi-Institutional Collaborative Cohort Study発表情報：Alcohol 巻: 89 ページ: 129-138キーワード：概要：To investigate the association between alcohol intake pattern in amount and frequency and metabolic syndrome (Mets) components, we simulated the change in the prevalence of Mets components by intake reduction. In order to manage Mets, alcohol intake reduction with moderation of intake pattern is required. However, evidence investigating the comparative impact of alcohol intake reduction in amount and frequency for Mets components is limited. We conducted a large-scale cross-sectional study in the general Japanese population. The study subjects included 37,371 non-drinkers and current drinkers recruited in the Japan Multi-Institutional Collaborative Cohort Study. Odds ratios (ORs) for Mets components according to alcohol intake amount and frequency were estimated using multiple logistic regression model. The prevalence of Mets components was estimated after assumed alcohol intake reduction of (a) none, (b) 10 g/day (men) or 5 g/day (women), (c) 20 g/day (men) or 10 g/day (women), (d) less than 20 g/day (men) or 10 g/day (women) for moderate-to-heavy drinkers, (e) 1-2 times/week, and (f) 3-4 times/week. The ORs with alcohol intake amount and frequency increased on high blood pressure while decreased on dyslipidemia. A J-shaped association was observed between intake amount and Mets. The estimated prevalence (%) of high blood pressure and dyslipidemia in men were (a) 45.2, (b) 43.0, (c) 41.4, (d) 40.4, (e) 42.9, and (f) 42.0 and (a) 50.3, (b) 51.8, (c) 52.9, (d) 50.2, (e) 52.7, and (f) 53.4, respectively. The estimated prevalence of high blood pressure in women did not evidently decrease. Simulated alcohol intake reduction showed decreased prevalence for high blood pressure and increased prevalence for dyslipidemia in men after reduced intake amount and frequency. The largest decreased prevalence for high blood pressure was observed in men when all moderate-to-heavy drinkers reduced their alcohol intake amount to less than 20 g/day.抄録：英語フィールド
Author：*Ippei Shimoshikiryo, Rie Ibusuki, Keiichi Shimatani, Daisaku Nishimoto, Toshiro Takezaki, Yuichiro Nishida, Chisato Shimanoe, Asahi Hishida, Takashi Tamura, Rieko Okada, Yoko Kubo, Etsuko Ozaki, Daisuke Matsui, Sadao Suzuki, Hiroko Nakagawa-Senda, Kiyonori Kuriki, Yoshikuni Kita, Naoyuki Takashima, Kokichi Arisawa, Hirokazu Uemura, Hiroaki Ikezaki, Norihiro Furusyo, Isao Oze, Yuriko N Koyanagi, Haruo Mikami, Yohko Nakamura, Mariko Naito, Kenji Wakai, J-MICC Study GroupTitle：Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction: A cross-sectional study from the Japan Multi-Institutional Collaborative Cohort StudyAnnouncement information:Alcohol Vol: 89 Page: 129-138An abstract：To investigate the association between alcohol intake pattern in amount and frequency and metabolic syndrome (Mets) components, we simulated the change in the prevalence of Mets components by intake reduction. In order to manage Mets, alcohol intake reduction with moderation of intake pattern is required. However, evidence investigating the comparative impact of alcohol intake reduction in amount and frequency for Mets components is limited. We conducted a large-scale cross-sectional study in the general Japanese population. The study subjects included 37,371 non-drinkers and current drinkers recruited in the Japan Multi-Institutional Collaborative Cohort Study. Odds ratios (ORs) for Mets components according to alcohol intake amount and frequency were estimated using multiple logistic regression model. The prevalence of Mets components was estimated after assumed alcohol intake reduction of (a) none, (b) 10 g/day (men) or 5 g/day (women), (c) 20 g/day (men) or 10 g/day (women), (d) less than 20 g/day (men) or 10 g/day (women) for moderate-to-heavy drinkers, (e) 1-2 times/week, and (f) 3-4 times/week. The ORs with alcohol intake amount and frequency increased on high blood pressure while decreased on dyslipidemia. A J-shaped association was observed between intake amount and Mets. The estimated prevalence (%) of high blood pressure and dyslipidemia in men were (a) 45.2, (b) 43.0, (c) 41.4, (d) 40.4, (e) 42.9, and (f) 42.0 and (a) 50.3, (b) 51.8, (c) 52.9, (d) 50.2, (e) 52.7, and (f) 53.4, respectively. The estimated prevalence of high blood pressure in women did not evidently decrease. Simulated alcohol intake reduction showed decreased prevalence for high blood pressure and increased prevalence for dyslipidemia in men after reduced intake amount and frequency. The largest decreased prevalence for high blood pressure was observed in men when all moderate-to-heavy drinkers reduced their alcohol intake amount to less than 20 g/day.