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Early prophylaxis of central venous catheter-related thrombosis using 1% chlorhexidine gluconate and chlorhexidine-gel-impregnated dressings: a retrospective cohort study

発表形態:
原著論文
主要業績:
主要業績
単著・共著:
共著
発表年月:
2020年09月
DOI:
10.1038/s41598-020-72709-w
会議属性:
指定なし
査読:
有り
リンク情報:

日本語フィールド

著者:
○Yamashita T, Takamori A, Nakagawachi A, Tanigawa Y, Hamada Y, Aoki Y, Sakaguchi Y
題名:
Early prophylaxis of central venous catheter-related thrombosis using 1% chlorhexidine gluconate and chlorhexidine-gel-impregnated dressings: a retrospective cohort study
発表情報:
Sci Rep 巻: 10 号: 1 ページ: 15952
キーワード:
概要:
To determine the prophylactic effect of using combined 1% alcoholic chlorhexidine gluconate and chlorhexidine gel-impregnated dressings (CGCD) on catheter-related thrombosis (CRT) in critically ill patients. This retrospective cohort study was performed in an intensive care unit from November 2009 to August 2014. The CRT incidence diagnosed with ultrasound examination was compared between patients applying CGCD and combined 10% aqueous povidone-iodine and standard transparent dressings (PITD) after central venous catheter insertion into the internal jugular vein for ≥ 48 h. CRT was stratified into early (within 7 days) and late (days 8–14) thromboses. Multivariate analyses using logistic regression models clarified the relationships between early- and late-CRT risks and skin antiseptic and catheter site dressing combinations. CRT occurred in 74 of 134 patients (55%), including 52 with early CRT and 22 with late CRT. Patients receiving CGCD had a significantly lower incidence of early CRT than those receiving PITD (odds ratio = 0.18; 95% confidence interval = 0.07–0.45, p  < .001). No significant association was evident between using CGCD and late CRT (p  = .514). Compared to PITD, CGCD reduced the CRT risk over 7 days in critically ill patients.
抄録:

英語フィールド

Author:
○Yamashita T, Takamori A, Nakagawachi A, Tanigawa Y, Hamada Y, Aoki Y, Sakaguchi Y
Title:
Early prophylaxis of central venous catheter-related thrombosis using 1% chlorhexidine gluconate and chlorhexidine-gel-impregnated dressings: a retrospective cohort study
Announcement information:
Sci Rep Vol: 10 Issue: 1 Page: 15952
An abstract:
To determine the prophylactic effect of using combined 1% alcoholic chlorhexidine gluconate and chlorhexidine gel-impregnated dressings (CGCD) on catheter-related thrombosis (CRT) in critically ill patients. This retrospective cohort study was performed in an intensive care unit from November 2009 to August 2014. The CRT incidence diagnosed with ultrasound examination was compared between patients applying CGCD and combined 10% aqueous povidone-iodine and standard transparent dressings (PITD) after central venous catheter insertion into the internal jugular vein for ≥ 48 h. CRT was stratified into early (within 7 days) and late (days 8–14) thromboses. Multivariate analyses using logistic regression models clarified the relationships between early- and late-CRT risks and skin antiseptic and catheter site dressing combinations. CRT occurred in 74 of 134 patients (55%), including 52 with early CRT and 22 with late CRT. Patients receiving CGCD had a significantly lower incidence of early CRT than those receiving PITD (odds ratio = 0.18; 95% confidence interval = 0.07–0.45, p  < .001). No significant association was evident between using CGCD and late CRT (p  = .514). Compared to PITD, CGCD reduced the CRT risk over 7 days in critically ill patients.


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