日本語フィールド
著者:*井芹 有紀, 大山 隆, 高守 史子, 宮川 純子, 林 愛, 富樫 理子, 酒見 隆信, 梅村 創, 南 美和子, 市場 正良, 岩坂 剛題名:人間ドック受診者におけるHelicobacter pylori感染と健診データの関連性発表情報:人間ドック(Ningen Dock) 巻: 34 号: 5 ページ: 693-701キーワード:概要:目的:Helicobacter pylori(H.pylori)感染と人間ドック受診者の健診データとの関連を調べた。方法:2013年から2015年に高木病院予防医学センターで人間ドックを受診し、抗H.pylori抗体を検査した未除菌者(基礎疾患合併者を除く)1,816名(年齢51.5歳、男性53.4%)を対象とした。陰性907名(年齢50.1歳、男性52.1%)、陽性909名(年齢52.8歳、男性54.7%)であった。男性970名(年齢52.5歳、陽性率51.2%)、女性846名(年齢50.4歳、陽性率48.7%)であった。結果:年齢補正後重回帰分析で、H.pylori陰性と陽性で有意差を認めた項目は、WBC(p<0.001、β=243.84)、HDL-C(p=0.002、β=-2.17)、LDL-C(p=0.003、β=3.94)、血小板数(p=0.007、β=0.62)、Hb(p=0.024、β=-0.16)であった。男性でHb(p=0.003、β=-0.2)、女性でWBC(p<0.001、β=372.27)、HDL-C(p=0.002、β=-2.98)、Hb(p=0.014、β=-0.19)、血小板数(p=0.015、β=0.85)、LDL-C(p=0.028、β=4.23)に差を認めた。結論:H.pylori感染は血算や血清脂質と関連があり、女性の方が影響を受けやすいことが示された。抄録:英語フィールド
Author:*Yuki Izeri, Takashi Oyama, Ayako Takamori, Junko Miyakawa, Ai Hayashi, Riko Togashi, Takanobu Sakemi, Tsukuru Umemura, Miwako Minami, Masayoshi Ichiba, Tsuyoshi IwasakaTitle:Relationship between Helicobacter pylori Infection and Multiphasic Health Check-up DataAnnouncement information:Official Journal of Japan Society of Ningen Dock Vol: 34 Issue: 5 Page: 693-701An abstract:Objective: The aim of the present study was to examine the influence of Helicobacter pylori (H. pylori) infection on multiphasic health check-up data.
Methods: Among individuals who received a multiphasic health check-up at Takagi hospital, we included those who underwent a serum anti-H. pylori IgG test. Those who had received H. pylori eradication therapy and had comorbidities were excluded. There were a total of 1,816 subjects in the present study (H. pylori negative: 907, H. pylori positive 909), consisting of 970 men (positive, 51.2%), and 846 women (positive, 48.7%).
Results: Data were analyzed by the multiple regression technique after adjusting for age. A significant difference between H. pylori negative and positive was observed for the following factors: WBC (p < 0.001, β = 243.84), HDL-C (p = 0.002, β =–2.17), LDL-C (p = 0.003, β = 3.94), platelets (p = 0.007, β =0.62), Hb (p = 0.024, β = –0.16). In men, a significant difference between negative and positive was observed for Hb (p = 0.003, β = –0.2) and in women, there were significant differences for WBC (p < 0.001, β = 372.27), HDL-C (p = 0.002, β = –2.98), Hb (p = 0.014, β = –0.19), platelets (p = 0.015, β = 0.85), and LDL-C (p = 0.028, β = 4.23).
Conclusion: Blood cell counts and serum lipids were influenced by H. pylori infection, and the effect of H. pylori was more potent in women than in men.