日本語フィールド
著者：Mai Fujita, Kazuharu Kamachi, Masako Yokoo, Keisuke Kidoguchi, Kana Kusaba, Haruna Kizuka-Sano, Kyosuke Yamaguchi, Atsujiro Nishioka, Mariko Yoshimura, Yasushi Kubota, Toshihiko Ando, Kensuke Kojima, Shinya Kimura題名：Accelerated Phase of Atypical Chronic Myeloid Leukemia with Severe Disseminated Intravascular Coagulation at Initial Presentation発表情報：Intern Med 巻: 59 号: 12 ページ: 1549-1553キーワード：概要：Patients with myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) are often asymptomatic and thus can remain undiagnosed until they become symptomatic due to progression to the accelerated phase (AP) or transformation to acute leukemia (leukemic transformation; LT). We herein report the case of a previously healthy 38-year-old man who had hyperleukocytosis with dysplastic myeloid precursor cells and severe disseminated intravascular coagulation. Hematopoietic recovery with features of atypical chronic myeloid leukemia (aCML) after induction chemotherapy was a diagnostic clue. Although rare, this case highlights the limitation of the diagnostic approach for aCML with AP or LT at the initial presentation.抄録：英語フィールド
Author：Mai Fujita, Kazuharu Kamachi, Masako Yokoo, Keisuke Kidoguchi, Kana Kusaba, Haruna Kizuka-Sano, Kyosuke Yamaguchi, Atsujiro Nishioka, Mariko Yoshimura, Yasushi Kubota, Toshihiko Ando, Kensuke Kojima, Shinya KimuraTitle：Accelerated Phase of Atypical Chronic Myeloid Leukemia with Severe Disseminated Intravascular Coagulation at Initial PresentationAnnouncement information:Intern Med Vol: 59 Issue: 12 Page: 1549-1553An abstract：Patients with myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) are often asymptomatic and thus can remain undiagnosed until they become symptomatic due to progression to the accelerated phase (AP) or transformation to acute leukemia (leukemic transformation; LT). We herein report the case of a previously healthy 38-year-old man who had hyperleukocytosis with dysplastic myeloid precursor cells and severe disseminated intravascular coagulation. Hematopoietic recovery with features of atypical chronic myeloid leukemia (aCML) after induction chemotherapy was a diagnostic clue. Although rare, this case highlights the limitation of the diagnostic approach for aCML with AP or LT at the initial presentation.