日本語フィールド
著者：*Rachana Manandhar Shrestha, Tetsuya Mizoue, Norie Sawada, Keitaro Matsuo, Keiko Wada, Keitaro Tanaka, Yingsong Lin, Yumi Sugawara, Hidemi Takimoto, Takashi Kimura, Hidemi Ito, Tetsuhisa Kitamura, Ritsu Sakata, Shiori Tanaka, Manami Inoue, Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan題名：Adult height in relation to the risk of colorectal cancer among the Japanese population: an evaluation based on systematic review and meta-analysis 発表情報：Jpn J Clin Oncol 巻: 52 号: 4 ページ: 322-330キーワード：Japanese; colon cancer; colorectal cancer; height; meta-analysis; rectal cancer; systematic review概要：Objective: The association between adult-attained height and risk of colorectal cancer remains elusive among the Japanese population. We performed a systematic review and meta-analysis of epidemiological studies in Japan.
Methods: We systematically searched the MEDLINE (PubMed) and Ichushi databases and complemented it with manual search to identify eligible studies. We extracted relative risks or odds ratios from the selected studies and conducted meta-analysis to estimate the summary relative risk with 95% confidence interval. We made the final judgment based on a consensus of the research group members considering both epidemiological evidence and biological plausibility.
Results: This systematic review identified four cohort and one case-control studies among the Japanese. The meta-analysis of these five studies showed the summary relative risk of 1.21 (95% confidence interval: 1.07-1.35) of overall colorectal cancer for the highest vs. lowest categories of height. In the analysis by the cancer subsite, the association was significant for colon cancer with a summary relative risk of 1.26 (95% confidence interval: 1.10-1.45) but not for rectal cancer 1.05 (95% confidence interval: 0.71-1.54). In the analysis by sex, tall stature was associated with a significantly increased risk of overall colorectal cancer in both sexes; the summary relative risk was 1.21 (95% confidence interval: 1.04-1.41) in men and 1.20 (95% confidence interval: 1.00-1.44) in women, respectively.
Conclusions: The evidence to support that adult-attained height is associated with increased risk of colorectal cancer (colon cancer) among the Japanese population is 'probable'.抄録：英語フィールド
Author：*Rachana Manandhar Shrestha, Tetsuya Mizoue, Norie Sawada, Keitaro Matsuo, Keiko Wada, Keitaro Tanaka, Yingsong Lin, Yumi Sugawara, Hidemi Takimoto, Takashi Kimura, Hidemi Ito, Tetsuhisa Kitamura, Ritsu Sakata, Shiori Tanaka, Manami Inoue, Research Group for the Development and Evaluation of Cancer Prevention Strategies in JapanTitle：Adult height in relation to the risk of colorectal cancer among the Japanese population: an evaluation based on systematic review and meta-analysis Announcement information:Jpn J Clin Oncol Vol: 52 Issue: 4 Page: 322-330Keyword：Japanese; colon cancer; colorectal cancer; height; meta-analysis; rectal cancer; systematic reviewAn abstract：Objective: The association between adult-attained height and risk of colorectal cancer remains elusive among the Japanese population. We performed a systematic review and meta-analysis of epidemiological studies in Japan.
Methods: We systematically searched the MEDLINE (PubMed) and Ichushi databases and complemented it with manual search to identify eligible studies. We extracted relative risks or odds ratios from the selected studies and conducted meta-analysis to estimate the summary relative risk with 95% confidence interval. We made the final judgment based on a consensus of the research group members considering both epidemiological evidence and biological plausibility.
Results: This systematic review identified four cohort and one case-control studies among the Japanese. The meta-analysis of these five studies showed the summary relative risk of 1.21 (95% confidence interval: 1.07-1.35) of overall colorectal cancer for the highest vs. lowest categories of height. In the analysis by the cancer subsite, the association was significant for colon cancer with a summary relative risk of 1.26 (95% confidence interval: 1.10-1.45) but not for rectal cancer 1.05 (95% confidence interval: 0.71-1.54). In the analysis by sex, tall stature was associated with a significantly increased risk of overall colorectal cancer in both sexes; the summary relative risk was 1.21 (95% confidence interval: 1.04-1.41) in men and 1.20 (95% confidence interval: 1.00-1.44) in women, respectively.
Conclusions: The evidence to support that adult-attained height is associated with increased risk of colorectal cancer (colon cancer) among the Japanese population is 'probable'.