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Low-intensity cigarette smoking and mortality risks: a pooled analysis of prospective cohort studies in Japan

発表形態:
原著論文
主要業績:
主要業績
単著・共著:
共著
発表年月:
2022年08月
DOI:
10.1093/ije/dyab224
会議属性:
指定なし
査読:
有り
リンク情報:

日本語フィールド

著者:
*Maki Inoue-Choi, Neal D Freedman, Eiko Saito, Shiori Tanaka, Mayo Hirabayashi, Norie Sawada, Shoichiro Tsugane, Yoshiaki Usui, Hidemi Ito, Chaochen Wang, Akiko Tamakoshi, Taro Takeuchi, Yuri Kitamura, Mai Utada, Kotaro Ozasa, Yumi Sugawara, Ichiro Tsuji, Keiko Wada, Chisato Nagata, Taichi Shimazu, Tetsuya Mizoue, Keitaro Matsuo, Mariko Naito, Keitaro Tanaka, Kota Katanoda, Manami Inoue, Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
題名:
Low-intensity cigarette smoking and mortality risks: a pooled analysis of prospective cohort studies in Japan
発表情報:
Int J Epidemiol 巻: 51 号: 4 ページ: 1276-1290
キーワード:
Japan; Low-intensity smoking; cessation; cigarette; mortality; smoking; smoking-related death
概要:
Background: Increasing proportions of smokers in Japan smoke <10 cigarettes per day (CPD). Yet, the health risks of low-intensity smoking in Asia are poorly understood. Methods: We performed a pooled analysis of 410 294 adults from nine population-based prospective cohort studies participating in the Japan Cohort Consortium. Cigarette-use data were collected at each study baseline in 1983-1994. Study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause and cause-specific mortality were calculated using multivariable-adjusted Cox regression by CPD among current smokers and by age at cessation among former smokers, with never smokers as the referent group. Pooled HRs and CIs were computed using a random-effect model. Results: The smoking prevalence was 54.5% in men and 7.4% in women. About 15.5% of male and 50.4% of female current smokers smoked 1-10 CPD (low-intensity). Both male and female low-intensity smokers had higher all-cause mortality risks than never smokers. Risks were further higher with increasing CPD in a dose-response manner. HRs (95% CIs) were 1.27 (0.97-1.66), 1.45 (1.33-1.59) and 1.49 (1.38-1.62) for 1-2, 3-5 and 6-10 CPD, respectively, in men; 1.28 (1.01-1.62), 1.49 (1.34-1.66) and 1.68 (1.55-1.81) for 1-2, 3-5 and 6-10 CPD, respectively, in women. Similar associations were observed for smoking-related causes of death. Among former low-intensity smokers, younger age at cessation was associated with lower mortality risk. Conclusions: Smoking very low amounts was associated with increased mortality risks in Japan. All smokers should quit, even if they smoke very few CPD.
抄録:

英語フィールド

Author:
*Maki Inoue-Choi, Neal D Freedman, Eiko Saito, Shiori Tanaka, Mayo Hirabayashi, Norie Sawada, Shoichiro Tsugane, Yoshiaki Usui, Hidemi Ito, Chaochen Wang, Akiko Tamakoshi, Taro Takeuchi, Yuri Kitamura, Mai Utada, Kotaro Ozasa, Yumi Sugawara, Ichiro Tsuji, Keiko Wada, Chisato Nagata, Taichi Shimazu, Tetsuya Mizoue, Keitaro Matsuo, Mariko Naito, Keitaro Tanaka, Kota Katanoda, Manami Inoue, Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Title:
Low-intensity cigarette smoking and mortality risks: a pooled analysis of prospective cohort studies in Japan
Announcement information:
Int J Epidemiol Vol: 51 Issue: 4 Page: 1276-1290
Keyword:
Japan; Low-intensity smoking; cessation; cigarette; mortality; smoking; smoking-related death
An abstract:
Background: Increasing proportions of smokers in Japan smoke <10 cigarettes per day (CPD). Yet, the health risks of low-intensity smoking in Asia are poorly understood. Methods: We performed a pooled analysis of 410 294 adults from nine population-based prospective cohort studies participating in the Japan Cohort Consortium. Cigarette-use data were collected at each study baseline in 1983-1994. Study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause and cause-specific mortality were calculated using multivariable-adjusted Cox regression by CPD among current smokers and by age at cessation among former smokers, with never smokers as the referent group. Pooled HRs and CIs were computed using a random-effect model. Results: The smoking prevalence was 54.5% in men and 7.4% in women. About 15.5% of male and 50.4% of female current smokers smoked 1-10 CPD (low-intensity). Both male and female low-intensity smokers had higher all-cause mortality risks than never smokers. Risks were further higher with increasing CPD in a dose-response manner. HRs (95% CIs) were 1.27 (0.97-1.66), 1.45 (1.33-1.59) and 1.49 (1.38-1.62) for 1-2, 3-5 and 6-10 CPD, respectively, in men; 1.28 (1.01-1.62), 1.49 (1.34-1.66) and 1.68 (1.55-1.81) for 1-2, 3-5 and 6-10 CPD, respectively, in women. Similar associations were observed for smoking-related causes of death. Among former low-intensity smokers, younger age at cessation was associated with lower mortality risk. Conclusions: Smoking very low amounts was associated with increased mortality risks in Japan. All smokers should quit, even if they smoke very few CPD.


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