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Association between habitual coffee consumption and skeletal muscle mass in middle-aged and older Japanese people

発表形態:
原著論文
主要業績:
主要業績
単著・共著:
共著
発表年月:
2021年10月
DOI:
10.1111/ggi.14264
会議属性:
指定なし
査読:
有り
リンク情報:

日本語フィールド

著者:
Chiharu Iwasaka, Yosuke Yamada, Yuichiro Nishida, Megumi Hara, Jun Yasukata, Nobuyuki Miyoshi, Chisato Shimanoe, Hinako Nanri, Takuma Furukawa, Kayoko Koga, Mikako Horita, Yasuki Higaki, Keitaro Tanaka
題名:
Association between habitual coffee consumption and skeletal muscle mass in middle-aged and older Japanese people
発表情報:
Geriatr Gerontol Int 巻: 21 号: 10 ページ: 950-958
キーワード:
概要:
Aims: Coffee consumption has been suggested, in animal studies, to inhibit the progression of sarcopenia, possibly through its anti-inflammatory effects; however, few studies have been carried out in humans. We aimed to examine whether coffee consumption was related to indicators of sarcopenia in a Japanese population, and whether the association was mediated by reduced inflammation. Methods: This study was a cross-sectional design. Participants were community residents (n = 6369) aged 45-74 years. We measured skeletal muscle mass index (SMI; kg/m2 ) by a bioelectrical impedance method, and grip strength with a Smedley-type dynamometer. Habitual coffee consumption was assessed by a self-administered questionnaire. Serum high-sensitivity C-reactive protein was measured as an inflammatory marker. The association between habitual coffee consumption and SMI or grip strength was analyzed with a linear regression model adjusted for covariates. Results: A significant positive association was found between coffee consumption and SMI (men: β = 0.023; Ptrend = 0.004, women: β = 0.011; Ptrend = 0.012). Further adjustment for high-sensitivity C-reactive protein did not materially alter the results (men: β = 0.023; Ptrend = 0.005, women: β = 0.009; Ptrend = 0.024). The relationship between coffee consumption and grip strength did not reach statistical significance; however, a positive trend was observed (men: β = 0.208; Ptrend = 0.085, women: β = 0.092; Ptrend = 0.167). Conclusions: We found that coffee consumption was positively associated with SMI independently of inflammation in middle-aged and older Japanese people. Reduced inflammation by coffee does not seem to be an important mediator, and further investigations are required to explore the mechanisms of this association. Geriatr Gerontol Int 2021
抄録:

英語フィールド

Author:
Chiharu Iwasaka, Yosuke Yamada, Yuichiro Nishida, Megumi Hara, Jun Yasukata, Nobuyuki Miyoshi, Chisato Shimanoe, Hinako Nanri, Takuma Furukawa, Kayoko Koga, Mikako Horita, Yasuki Higaki, Keitaro Tanaka
Title:
Association between habitual coffee consumption and skeletal muscle mass in middle-aged and older Japanese people
Announcement information:
Geriatr Gerontol Int Vol: 21 Issue: 10 Page: 950-958
An abstract:
Aims: Coffee consumption has been suggested, in animal studies, to inhibit the progression of sarcopenia, possibly through its anti-inflammatory effects; however, few studies have been carried out in humans. We aimed to examine whether coffee consumption was related to indicators of sarcopenia in a Japanese population, and whether the association was mediated by reduced inflammation. Methods: This study was a cross-sectional design. Participants were community residents (n = 6369) aged 45-74 years. We measured skeletal muscle mass index (SMI; kg/m2 ) by a bioelectrical impedance method, and grip strength with a Smedley-type dynamometer. Habitual coffee consumption was assessed by a self-administered questionnaire. Serum high-sensitivity C-reactive protein was measured as an inflammatory marker. The association between habitual coffee consumption and SMI or grip strength was analyzed with a linear regression model adjusted for covariates. Results: A significant positive association was found between coffee consumption and SMI (men: β = 0.023; Ptrend = 0.004, women: β = 0.011; Ptrend = 0.012). Further adjustment for high-sensitivity C-reactive protein did not materially alter the results (men: β = 0.023; Ptrend = 0.005, women: β = 0.009; Ptrend = 0.024). The relationship between coffee consumption and grip strength did not reach statistical significance; however, a positive trend was observed (men: β = 0.208; Ptrend = 0.085, women: β = 0.092; Ptrend = 0.167). Conclusions: We found that coffee consumption was positively associated with SMI independently of inflammation in middle-aged and older Japanese people. Reduced inflammation by coffee does not seem to be an important mediator, and further investigations are required to explore the mechanisms of this association. Geriatr Gerontol Int 2021


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