日本語フィールド
著者：Nonaka T, Nagaishi Y, Murata D, Hara H, Nakayama K題名：3D Printing in Nephrology発表情報：Innovations in Nephrology ページ: 141–156キーワード：Tissue engineering, Bio-3D printing, Kidney biofabrication, Kidney organoid, Urine excretion pathway
Decellularization, Kenzan method概要：Renal replacement therapy is currently limited to dialysis and renal transplantation, and the development of new technologies to regenerate kidney function is being pursued. Bioengineered tissue regeneration can now produce three-dimensional (3D) structures, and bio-3D printing technology, a revolutionary advancement, has given hope to creating cell-derived kidney tissue. Bioprinting the entire functional kidney has not been completed, but some studies have done so with a portion of the nephron. Embryonic stem cells or induced pluripotent stem cell-derived kidney organoids have been generated, which functionally mature after transplantation. Kidney decellularization induces the urine excretion pathway, and the Kenzan method is anticipated to develop regenerative kidney medicine. Although there are many challenges in producing kidneys, combining these methods is expected to create transplantable kidneys for humans in the future.抄録：英語フィールド
Author：Nonaka T, Nagaishi Y, Murata D, Hara H, Nakayama KTitle：3D Printing in NephrologyAnnouncement information:Innovations in Nephrology Page: 141–156Keyword：Tissue engineering, Bio-3D printing, Kidney biofabrication, Kidney organoid, Urine excretion pathway
Decellularization, Kenzan methodAn abstract：Renal replacement therapy is currently limited to dialysis and renal transplantation, and the development of new technologies to regenerate kidney function is being pursued. Bioengineered tissue regeneration can now produce three-dimensional (3D) structures, and bio-3D printing technology, a revolutionary advancement, has given hope to creating cell-derived kidney tissue. Bioprinting the entire functional kidney has not been completed, but some studies have done so with a portion of the nephron. Embryonic stem cells or induced pluripotent stem cell-derived kidney organoids have been generated, which functionally mature after transplantation. Kidney decellularization induces the urine excretion pathway, and the Kenzan method is anticipated to develop regenerative kidney medicine. Although there are many challenges in producing kidneys, combining these methods is expected to create transplantable kidneys for humans in the future.